选择性子宫动脉栓塞治疗子宫肌瘤

目前临床上治疗子宫肌瘤多采用肌瘤摘除术、子宫切除术及激素治疗.鉴于外科手术的创伤大和激素治疗的不良反应,选择性子宫动脉栓塞治疗子宫肌瘤无疑为子宫肌瘤患者提供了一种新的选择.笔者对15例子宫肌瘤患者进行子宫动脉栓塞治疗,现将结果报告如下.     

选择性子宫动脉栓塞术治疗子宫肌瘤的临床研究

目的 研究经导管行选择性子官动脉栓塞术治疗子宫肌瘤。方法 选择27例子宫肌癯患者。采用Seldinger方法行双侧选择性子宫动脉插管。造影证实后经导管注入PVA栓塞颗粒。阻断肌瘤供血。结果，经造影证实。子宫肌瘤多由双侧子宫动脉供血。一侧为主。且血流丰富。行双侧子宫动脉栓塞后。肌瘤供血可完全墨薪。治疗后3个月、6个月随访，肿瘤体积明显缩小。月经量及月经周期恢复正常。贫血及压迫症状改善。结论 选择性子宫动脉栓塞术治疗子宫肌瘤是一种疗效显著的微创治疗新方法。     

选择性栓塞子宫动脉治疗子宫肌瘤的临床研究

目的：研究双侧子宫动脉栓塞治疗子宫肌瘤的临床疗效。方法：32例子宫肌瘤患者，采用Seldinger方法，股动脉穿刺分别人双侧子宫动脉，经导管注人真丝线段和明胶海绵颗粒，阻断其血供。结果：30例成功栓塞的患者，临床症状均好转；29例肌瘤和f宫体积明显缩小；18例月经量及月经周期恢复正常，疼痛明显改善；32例均无严重并发症发生。结论：子宫肌瘤栓塞其两侧供血子宫动脉创伤小、临床效果满意，此疗法可成为替代外科手术的首选方法。     

选择性子宫动脉栓塞治疗子宫肌瘤的临床研究

目的 观察选择性子宫动脉栓塞治疗子宫肌瘤的临床效果。方法 21例子宫肌瘤患者采用Seldinger‘s方法作选择性子宫动脉栓塞治疗，经股动脉穿刺，将导管插入子宫动脉，造影，再经导管注入真丝线段，栓塞子宫动脉。结果 造影发现子宫肌瘤血供丰富，部分肌瘤血供来自肌瘤侧子宫动脉，部分肌瘤双侧子宫动脉均参与供血。栓塞肌瘤供血侧或双侧子宫动脉后子宫肌瘤血供可完全阻断。定期随诊结果月经量及月经周期恢复正常，肌瘤和子宫体积明显缩小，临床有效率达95．24％。结论 选择性子宫动脉栓塞治疗子宫肌瘤是一种微创伤、临床效果好的新方法。     

选择性子宫动脉栓塞治疗子宫肌瘤

子宫肌瘤是女性生殖器官最常见的良性肿瘤。临床上多以手术治疗为主，我院从2000-2002年，对20例子宫肌瘤患者采用Seidinger’s方法经皮行动脉穿刺插管。造影后确认子宫动脉及肌瘤位置后，进行超选择性，药物栓塞治疗，肌瘤较治疗前明显缩小，临床效果显著。     

选择性子宫动脉栓塞治疗子宫肌瘤的临床研究

目的 :观察选择性子宫动脉栓塞术治疗子宫肌瘤的临床效果。方法 :对 5 4例子宫肌瘤患者采用经股动脉穿刺插管法 ,用PVA作为栓塞剂 ,进行选择性子宫动脉栓塞治疗。术前及术后定期B超下测量子宫及肌瘤大小 ,记录术后相关症状变化。结果 :插管栓塞成功率 10 0 %,B超随访 1个月～ 12个月 ,治疗 6个月后 ,肌瘤体积平均缩小 5 8 2 1%,治疗 12个月后 ,平均缩小 75 15 %,93%患者经量恢复正常或明显减少。结论 :选择性子宫动脉栓塞治疗子宫肌瘤是一种微创性、临床效果好的治疗方法。     

超选择性介入栓塞子宫动脉治疗子宫肌瘤

子宫肌瘤是女性生殖系统最常见的良性肿瘤,传统的治疗方法是药物保守治疗和手术切除.近年来探索了多种保存子宫的疗法,其中超选择性子宫动脉插管栓塞法是较多使用的一种方法,具有微创、安全、可靠的优点.我科自2000年2月～2003年8月采用经皮股动脉穿刺超选择性栓塞双侧子宫动脉治疗16例子宫肌瘤患者,现报告如下.     

无水乙醇选择性子宫动脉栓塞治疗子宫肌瘤的护理

子宫肌瘤是女性常见性、多发性妇科疾病,经皮选择性子宫动脉栓塞治疗可直接阻断肌瘤的供血和雌激素对子宫肌瘤受体的作用,使瘤体发生缺血和缺少激素的刺激而缩小,正常子宫则可通过盆腔其它侧支血供,如卵巢动脉和阴道宫颈上动脉等获得营养不致坏死.既避免了剖腹手术,又保留了子宫和卵巢的正常生理功能.我院自0999-04～2002-04用无水乙醇栓塞治疗46例子营肌瘤患者,现报如下:     

选择性栓塞子宫动脉治疗子宫肌瘤的临床研究

目的研究双侧子宫动脉栓塞治疗子宫肌瘤的临床疗效.方法 32 例子宫肌瘤患者,采用 Seldinger 方法,股动脉穿刺分别入双侧子宫动脉,经导管注入真丝线段和明胶海绵颗粒,阻断其血供.结果30 例成功栓塞的患者,临床症状均好转;29 例肌瘤和子宫体积明显缩小;18 例月经量及月经周期恢复正常,疼痛明显改善;32例均无严重并发症发生.结论子宫肌瘤栓塞其两侧供血子宫动脉创伤小、临床效果满意,此疗法可成为替代外科手术的首选方法.     

聚乙烯醇超选择性栓塞子宫动脉治疗子宫肌瘤

【目的】探讨聚乙烯醇超选择性栓塞子宫动脉治疗子宫肌瘤的临床疗效。【方法】收集22例子宫动脉栓塞术治疗肌瘤的患者，观察临床表现。【结果】①患者子宫体积均数、肌瘤体积均数在栓塞术前后变化有统计学的差异（P〈0．05）。②栓塞术前后患者双侧卵巢体积变化无显著统计学差异（P〉0．05）。③患者月经量在栓塞术前后变化有统计学差异（P〈0．05）。【结论】①本疗法能有效地缩小子宫和肌瘤的体积；改善月经过多等临床症状。②本疗法对近期卵巢体积影响不大。③本疗法近期疗效良好，远期效果有待进一步的研究。④本疗法有一定的副作用和并发症，应加以重视。     

选择性子宫动脉栓塞治疗症状性子宫肌瘤

目的:评价选择性子宫动脉栓塞 (U AE)治疗症状性子宫肌瘤 (SUF)的临床疗效。方法:12例 SUF患者行双侧子宫肌瘤供血动脉的栓塞治疗 ,栓塞剂为聚乙烯醇微球颗粒 (PVA)。结果:栓塞成功率 10 0 % ,无严重并发症发生。随访 3～ 2 4个月 ,B超示术后 6个月肌瘤平均缩小 4 5 % ,1例肌瘤消失 ,均伴有月经量的明显减少。 结论 :U AE是治疗 SU F的安全方法 ,近期疗效肯定。     

子宫动脉栓塞治疗子宫肌瘤的临床疗效分析

目的 分析平阳霉素混合乳剂加明胶海绵在子宫动脉栓塞治疗症状性子宫肌瘤的疗效.方法 对50例符合筛选条件的症状性子宫肌瘤患者在数字减影技术指导下,采用平阳霉素及明胶海绵颗粒栓塞双侧子宫动脉,观察手术后症状缓解情况、子宫肌瘤缩小程度.结果 50例行栓塞治疗患者,除5例患者子宫肌瘤为多发,5个月后症状有明显缓解,其余45例临...     

子宫动脉栓塞术治疗子宫肌瘤的疗效观察

目的探讨子宫动脉栓塞术（UAE）治疗子宫肌瘤的临床疗效。方法对81例经B超、临床诊断的子宫肌瘤患者,以Seldinger’s技术超选择插管至双侧子宫动脉上行支,经DSA证实后,即施行UAE,栓塞剂选择平阳霉素乳剂（PLE）＋明胶海绵颗粒（GS）,分别于术后3、6、12个月进行彩超复查,观察疗效。结果 UAE后91.4%（74/81）病例临床症状缓解,92.6%（75/81）患者月经恢复正常。术后3、6、12个月复查,肌瘤缩小率分别为35%、55%、75%。结论子宫动脉栓塞术能有效地缩小肌瘤体积,并明显改善临床症状,是一种疗效显著的微创技术,对子宫肌瘤的治疗具有重要的临床应用价值。     

Dextran uterine artery embolization to treat fibroids

Objectives To analyze the technical aspects of uterine artery embolization with dextran mic rospheres and to evaluate the effectiveness of this technique as the primary tre atment of uterine fibroids in a series of 38 patients. Methods Thirty- eight volunteers (age range, 24-48 years; mean, 37. 2 years) with sympto ms caused by uterine fibroids (menorrhagia, mass- related symptoms, and pelvic p ain) were randomly included in this study. The fibroids were single in 32 patie nts and multiple in 6 patients. According to the tumor location, subserous fibr oids were found in 4 patients and interstitial or submucosal fibroids in 34. Tu mor size was from 2 to 10. 9 cm in diameter. We performed embolization with a s ingle Headhunter catheter using the right- femoral artery approach, injection of dextran microspheres (225-450 μm), and an absorbable gelatin sponge. Follow- up included clinical and sonographic examinations at one- month intervals for 6 months. Results Embolization was successfully performed in all patients. Post- procedural pain control was good in 35 (92%) patients. In most patients, symptoms were improved at 3 months (36/38, 95%). Clinical failure of the treatment occurred in only 2 patients (2/38, 5%). Progressive reduction in leiomyoma size was revealed duri ng sonographic follow- up, and the reduction rate at the sixth month after embol ization was 68%. The tumor had vanished in five submucosal fibroid patients. H istopathological tests showed that the tumor was degenerative as fibrosis and hy alinosis. Conclusions Uterine artery embolization with dextran microspheres is a micro- invasive metho d for the treatment of uterine fibroids. It is clinically effective in most pat ients and induces a progressive reduction in the size of fibroids. Based on thi s study, we believe that this new technique is much more suitable for submucosal fibroids with massive menorrhagia.     

子宫动脉栓塞术治疗子宫肌瘤的临床应用效果

目的:分析子宫动脉栓塞术对子宫肌瘤的疗效。方法:选择21例子宫肌瘤患者,行双侧子宫动脉栓塞进行治疗,分别记录患者的月经周期、经期、经量及瘤体变化。结果:治疗后经期时间和经量明显下降(P<0.01),E2和T的含量差异无统计学意义(P>0.05),治疗后瘤体明显缩小(P<0.01)。结论:子宫动脉栓塞术是一种有效治疗子宫肌瘤的方法,安全可靠,值得推广。     

选择性子宫动脉栓塞治疗症状性子宫肌瘤的疗效分析

目的:探讨子宫动脉栓塞治疗子宫肌瘤的临床疗效和副反应。方法:对48例症状性子宫肌瘤患者进行选择性子宫动脉栓塞治疗,随访12～18月,观察术后症状(月经量,月经期,血红蛋白)缓解情况、子宫及瘤体缩小程度和副反应。结果:显效28例(58.3%),有效14例(29.2%),无效6例(12.5%)。子宫平均缩小率为(40.8±15.6)%,肌瘤平均缩小率为(58.9±16.8)%。所有患者月经恢复正常,月经量减少及月经期缩短,血红蛋白升至正常范围,术后无严重并发症发生。结论:选择子宫动脉栓塞术治疗子宫肌瘤安全、有效、创伤小,值得推广应用。     

子宫动脉栓塞治疗子宫肌瘤的疗效及其影响因素分析

目的 探讨子宫动脉栓塞术(UAE)对子宫肌瘤的治疗效果,并对影响疗效的因素进行分析。方法 对36例症状性子宫肌瘤患者,经超选择性插管双侧子宫动脉内注入PVA颗粒栓塞治疗,术后3、6、12个月随访复查,观察患者临床症状改善和子宫肌瘤体积变化情况。结果 UAE术后患者子宫出血症状改善最为明显,栓塞后3、6、12个月肌瘤体积平均缩小分别为50．5％,56．3％,61.8％。肌壁间和黏膜下肌瘤的临床症状改善和体积缩小较浆膜下肌瘤明显。结论 双侧子宫动脉栓塞治疗子宫肌瘤是一种安全有效的新方法;其疗效与栓塞术后肌瘤血管的重新构建,肌瘤类型,血供状态,子宫动脉单双侧栓塞等多种因素有关。     

Effect of selective uterine artery embolization on symptomatic uterine fibroids

Objective： To evaluate the outcomes of selective uterine artery embolization （SUAE） in treatment of symptomatic uterine fibroids using Color Doppler ultrasonography （CDUS）. Methods： As the procedure SUAE for fibroids, prospective data of the initial 65 consecutive women treated from March 2007 to September 2009 were collected. The follow-up period from 1 week to 30 months, using questionnaires, we investigated the fibroid-related physical and psychological symptoms, and the cumulative rates of symptom control, gynecologic interventions, and complications. The volumes of uterine and uterine fibroids were calculated by CDUS pre- and post-SUAE for 6 months. And we tested the levels of internal hormone including FSH, LH and E2 before and after SUAE for 3, 6 months. Results： SUAE was performed successfully in all patients. There was no peri-operative morbidity in all procedures. Compared with pre-SUAE volumes of uterine [（322± 12） cm^3] and uterine fibroids [（125±46） cm^3], their volumes in post-SUAE were （144±72） cm^3 and （51 a：l 1） cm^3 （P〈0.01）, and reduction rate was 58% and 61%, respectively. At 3, 6 months after SUAE, levels of FSH, LH, and E2 were not decreased than that of in pre-SUAE （P〉0.05）. After SUAE for 24 months, the fibroids related physical and psychological symptoms such as bleeding, pain and quality of life were significantly improved （P〈0.01）. 90.8% （59/65） women had resolution of symptoms and no significant post-procedural symptoms. Parts of patients discharge necrotic fibroids. 86% （34/40） complications were minor, requiring no therapy. 9.2% （6/65） had significant post-procedural symptoms, requiring therapy in hospital or out-patient department. Conclusion： SUAE contributes to a long-term significant improvement of all investigated uterine fibroid-related symptoms and markedly improves women＇s health-related quality of life. SUAE that no impair on changes of internal hormone, under suitable conditions, represents an attractive alternative to hysterectomy for the treatment of symptomatic fibroids and is a minimally invasive, new method of good clinical prognosis. CDUS is an effective to investigate the outcome of SUAE.     

子宫动脉栓塞术治疗育龄期子宫肌瘤的疗效观察

目的评估子宫动脉栓塞术（UAE）治疗育龄期子宫肌瘤的疗效。方法选择61例育龄期子宫肌瘤患者,以Seldinger＇s技术超选择插管至双侧子宫动脉上行支,DSA证实后,行UAE,栓塞剂选择平阳霉素乳剂（PLE）＋明胶海绵颗粒（GS）。术后3个月、6个月、12个月随访,观察临床症状及肌瘤体积改变,对疗效进行评估。结果 UAE后全部患者如月经过多、压迫症状、腹痛等临床表现明显改善。术后3个月、6个月、12个月复查,肌瘤缩小率分别为35%、55%、75%。结论对于育龄期子宫肌瘤患者,子宫动脉栓塞术能有效地缩小肌瘤体积,并明显改善临床症状,可部分代替子宫切除术,具有重要临床价值。