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1.
目的 :探讨应用 Am platzer蘑菇伞器治疗小儿动脉导管未闭 ( PDA)的临床疗效及价值。方法 :本组共 68例 ,年龄 8个月~ 12岁 (平均 6.4岁 ) ,体重 6.5~ 3 0 (平均 18.2 ) kg,PDA直径为 3~ 8mm ,术中行右心导管检查取血 ,测压 ,术后 5~ 15 m in行降主动脉造影 ,测肺动脉压 ,主动脉压。术后 1月 ,3月 ,6月分别行 X线及超声心动图检查 ,了解有无残余分流及封堵器位置。结果 :本组 68例均应用 Am platzer PDA磨菇伞器治疗 ,成功率 10 0 % ,疗效满意 ,无并发症 ,术后 3 d行超声心动图检查显示无 1例分流。结论 :应用 Amplatzer蘑菇伞器治疗 PDA创伤小 ,操作简单 ,使用广泛 ,成功率高 ,临床疗效满意 相似文献
2.
目的 评价Amplatzer封堵器介入治疗动脉导管未闭(PDA)的临床疗效。方法 对10例管型PDA患儿用Amplatzer PDA封堵器进行堵闭,2例窗型PDA用Amplatzer房间隔双伞封堵器堵闭。在透视下经6F输送器置入封堵器,术后10分钟,行右心导管检查及主动脉弓降部造影,术后24小时、1、3个月分别行彩色多普勒超声心动图、血常规及肝肾功能检查,评价治疗效果。结果 本组技术成功率为100%,患儿心脏双期连续性杂音均消失,术后10分钟主动脉弓降部造影显示少量残余分流2例,均为窗型PDA。术后24小时超声心动图示上述2例仍有微量分流。术后24小时、1、3个月行彩色多普勒超声心动图检查,均未发现残余分流、PDA再通及封堵器移位,血常规及肝肾功能检查均正常。2例有分流的患儿术后均出现急性溶血,经积极内科治疗后好转。其余10例无并发症发生。结论 应用Amplatzer封堵器介入治疗PDA安全有效,近中期疗效满意,远期疗效尚待进一步观察。对窗型PDA可试用Amplatzer房间隔封堵器堵闭。对术后发生急性溶血者可采用内科治疗。 相似文献
3.
目的 :应用 Am platzer封堵器经导管治疗动脉导管未闭 (PDA)开胸术后再通并对其疗效进行评价。方法 :全组10例 ,年龄 11± 8(4~ 32 )岁。PDA最窄处直径为 4± 4(2~ 13) mm。封堵后 10 m in行侧位降主动脉造影 ,术后 1d及 1月行超声心动图检查 ,观察有无残余分流及 PDA再通。结果 :9例 PDA采用 Am platzer PDA封堵器治疗 ,1例采用 Amplatzer房间隔缺损封堵器治疗。术后 10 m in降主动脉造影显示 ,3例存在微量~少量残余分流 ,7例封堵完全无残余分流。术后 2 4h、术后 1月超声心动图均未见残余分流及再通。结论 :应用 Amplatzer封堵器治疗动脉导管未闭外科术后再通是一种安全有效的介入方法。 相似文献
4.
目的 :应用 Amplatzer封堵器经导管治疗直径≥ 8mm的大型动脉导管未闭 (PDA)并对其疗效进行评价。方法 :全组 5 0例 ,年龄 2 6 .4± 2 3.2 (4.0~ 6 0 .0 )岁。 PDA最窄处直径为 10 .2± 2 .3(8.0~ 15 .0 ) mm。封堵 10 m in后行侧位降主动脉造影 ,术后 1d及 1月行超声心动图检查 ,观察有无残余分流及 PDA再通。结果 :47例 PDA采用Amplatzer PDA封堵器治疗 ,2例采用 Amplatzer ASD封堵器治疗 ,1例 PDA伴有阻力性肺动脉高压未行介入治疗。术后 10 min降主动脉造影显示 ,19例存在微~少量残余分流 ,30例封堵完全无残余分流。术后 2 4h、术后 1月超声心动图未见残余分流及再通。结论 :应用 Am platzer封堵器治疗直径≥ 8mm的大型动脉导管未闭是一种安全有效的介入方法。 相似文献
5.
目的 :应用 Amplatzer封堵器经导管治疗动脉导管未闭 (PDA)术后随访。方法 :全组 16 9例。PDA最窄处直径为 4 .7± 3.8(2 .0~ 13.0 ) mm。封堵后 10 min行降主动脉造影 ,术后 2 4 h及 1,3,6月 ,1年行超声心动图检查随访。结果 :16 6例 PDA采用 Amplatzer PDA封堵器治疗 ,3例采用 Am platzer房间隔缺损封堵器治疗。 1例 PDA术中证实伴有阻力性肺动脉高压未行介入治疗。术后 10 m in降主动脉造影示 ,5 4例存在微~少量残余分流 ,114例封堵完全无残余分流。术后 2 4 h13例存在微~少量残余分流 ,余超声心动图未见残余分流及再通。 1例封堵术后 10h并发溶血 ,4 8h后行外科 PDA缝合术。术后 1月超声心动图检查 5例存在少量残余分流 ,术后 3月 4例存在少量残余分流 ,6月及 1年 3例存在少量残余分流 ,最后行 PFM弹簧圈治疗未再见残余分流。无并发症发生。结论 :应用 Am platzer封堵器治疗 PDA是一种安全有效的介入方法 相似文献
6.
应用Amplatzer封堵器经导管治疗动脉导管未闭并发重度肺动脉高压的疗效评价 总被引:6,自引:0,他引:6
目的 :应用 Amplatzer封堵器经导管治疗动脉导管未闭 (PDA)并发重度肺动脉高压 (SPH) ,并对其疗效进行评价。方法 :全组 15例 ,年龄 2 5± 2 2 (5~ 54)岁。PDA最窄处直径为 11± 4(8~ 18) mm。 PDA 8例采用 AmplatzerPDA封堵器治疗 ,7例采用 Amplatzer房间隔缺损封堵器治疗。封堵后 3 0 min行侧位降主动脉造影 ,术后 1d及 1月行超声心动图检查 ,观察有无残余分流及 PDA再通。结果 :14例 (93 ) %封堵后 3 0 min至 1h肺动脉收缩压由 90~ 150 (10 6± 2 7) mm Hg降至 45~ 110 (65± 2 1) mm Hg,肺动脉平均压由 60~ 10 5(82± 2 1) mm Hg降至 2 6~ 65(50± 19) mm Hg。 1例封堵后 3 0 min至 1h肺动脉收缩压无下降 ,反而有轻度上升 ,考虑为阻力性重度肺动脉高压 ,撤出封堵器。 6例主动脉压力有不同程度增高。术后 3 0 min降主动脉造影示 ,5例存在微至少量残余分流 ,10例封堵完全无残余分流。在术后 2 4h2例仍存在微至少量残余分流 ,其中 1例并发溶血 ,48h后行外科 PDA缝合术。其余病例术后 1月超声心动图检查未见残余分流及再通。结论 :应用 Amplatzer封堵器治疗 PDA并发 SPH是一种安全有效的介入方法 相似文献
7.
目的 应用彩色多普勒超声心动图(CDFI)比较经导管五种方法堵闭小儿动脉导管未闭(PDA)的疗效。方法 1989年3月-1999年7月,超声心动图分别观察采用海绵塞(Porstman)、双面伞堵闭器(Rashkind0、纽扣式补片(Sideris)、弹簧圈闭(Coil)和蘑菇伞堵闭塞(Amplatzer)堵闭282例PDA患儿术前、术后1天、3个月、6个在动脉水平有无分流、心脏大小变化、闭器的位置及其血流动力学的改变。结果 5组患儿术后1天左室舒张末径(LVDD)和左房径(LA)明显缩小(P<0.001),6个月基本恢复正常;术后1天残余分流17%、3个月下降至6.4%。6个月无进一步下降。结论 Amplatzer和Coil闭法分别闭对小于或等于8.1mm和2.5mm的PDA远期疗效确切,已基本能替3代手术结扎的方法,值得在临床推广。 相似文献
8.
动脉导管未闭(PDA)是指主动脉和肺动脉之间的一种先天性的异常通道,多位于主动脉狭部和左肺动脉根部之间,是最常见的先天性心脏病之一,约占先天性心脏病的9%-12%,男女比例为1:3。目前临床应用的PDA介入封堵治疗方法常用的为Amplatzer法和弹簧栓子法两种,其中以Amplatzer应用较多。经导管Amplatzer蘑菇伞封堵术技术成功率为98%,与其他PDA封堵技术相比,具有疗效确切、操作简便等优点,可用于较大直径的PDA,且残余分流率低。 相似文献
9.
目的总结应用新型成角蘑菇伞治疗小儿动脉导管未闭(PDA)的经验,并对其疗效进行初步分析。方法全组共15(男5,女10)例,年龄5.5个月~8岁(2.8±2.5岁),3岁以内婴幼儿12例,体质量6~30kg。PDA最小内径2~12(5.9±3.1)mm,术前均有肺动脉高压,平均肺动脉压为34~65mmHg。选用新型封堵伞直径6~20(12.9±4.2)mm。结果15例均获得成功。重复主动脉造影,无主动脉腔内狭窄和变形,无明显造影剂分流后释放封堵器。术后12例即刻无分流,3例有少量残余分流,术后24h超声心动图示分流消失,肺动脉压术后均有下降。结论应用新型成角蘑菇伞治疗小儿特殊类型PDA适应证范围广,成功率高,治疗效果好。 相似文献
10.
关于婴幼儿动脉导管未闭介入治疗的临床研究 总被引:1,自引:0,他引:1
目的:探讨Amplatzer法介入封堵治疗婴幼儿动脉导管未闭(PDA)的经验,治疗意义,操作技术及安全性。方法:回顾性分析32例婴幼儿PDA患儿资料,患儿年龄≤3岁,平均(13±5.5)月,体重(10.3±4.2)kg;做右心导管,实行封堵术,术后24h,1、3、6、12月复查超声心动图。结果:32例患儿中29例(90.6%)封堵成功,PDA最窄处直径(4.2±2.1)mm。失败者2例为PDA封堵器主动脉侧过大,导致降主动脉局部狭窄、迂曲变形而放弃封堵,1例封堵术后封堵器周围大量残余分流,行外科手术治疗。并发症包括术后残余分流、股动脉搏动减弱及伤口出血等。结论:在严格选择适应证的条件下,介入封堵婴幼儿动脉导管未闭较为安全,可行。 相似文献
11.
Fernández Ruiz A del Cerro Marín MJ Rubio Vidal D Castro Gussoni MC Moreno Granados F 《Revista espa?ola de cardiología》2002,55(10):1057-1062
INTRODUCTION AND OBJECTIVES: Transcatheter closure of patent ductus arteriosus is a well-established procedure. The aim of this study was to assess the initial and mid-term results of the treatment of PDA with the Amplatzer duct occluder. PATIENTS AND METHODS: From October 1999 to December 2001, 30 children underwent transcatheter closure of persistent ductus arteriosus at a mean SD age of 5 4.02 years (range: 3 months to 14 years) and weight of 20.3 10.3 kg (range: 4.5-45 kg). Infants under 10 kg weight made up 46% of total patients. A lateral view aortogram was made to determine the morphology of the ductus and select the size of the device. Occlusion was achieved using the anterograde venous approach. Follow-up evaluations were made with chest X-ray and echocardiogram at 24 hours and 1, 4 and 12 months after implantation. RESULTS: Twenty-eight patients (93.3%) immediately achieved complete occlusion, and on color Doppler examination the closure rate was 100% within 24 hours of implantation. There was no device embolization. In the follow-up, a 19-month-old patient developed a 20 mmHg gradient across the aortic arch. CONCLUSIONS: Patent ductus arteriosus can be easily occluded with the Amplatz Duct Occluder, which is effective and particularly useful in infants and children with relatively large PDA. Further experience and long-term follow-up are still needed to assess the safety of this device in smaller children. 相似文献
12.
The Amplatzer duct occluder: experience in 209 patients 总被引:56,自引:0,他引:56
Bilkis AA Alwi M Hasri S Haifa AL Geetha K Rehman MA Hasanah I 《Journal of the American College of Cardiology》2001,37(1):258-261
OBJECTIVES: The aim of the study was to assess the safety and efficacy of the Amplatzer ductal occluder (ADO) in transcatheter occlusion of patent ductus arteriosus (PDA). BACKGROUND: Transcatheter closure of small to moderate sized PDAs is an established procedure. The ADO is a self-expandable device with a number of salutary features, notably its retrievability, ease of delivery via small 5F to 7F catheters and a range of sizes suitable even for the larger PDAs. METHODS: Between November 1997 and August 1999, the ADO was successfully implanted in 205 of 209 patients with PDA. The inclusion criteria for this device occlusion method were patients with clinical and echocardiographic features of moderate to large PDA, weighing > or =3.5 kg as well as asymptomatic adolescents and adults with PDA measuring > or =5.0 mm on two-dimensional (2D) echocardiogram. Occlusion was achieved via the antegrade venous approach. Follow-up evaluations were performed with 2D echocardiogram, color-flow mapping and Doppler measurement of the descending aorta and left pulmonary artery velocity at 24 h and 1, 3, 6 and 12 months after implantation. RESULTS: Two hundred and five patients had successful PDA occlusion using this device. The patients were between two months and 50 years (median 1.9) and weighed between 3.4 kg and 63.2 (median 8.4). Infants made up 26% of the total patients. The PDA measured from 1.8 to 12.5 mm (mean 4.9) at the narrowest diameter. Forty-four percent of patients achieved immediate complete occlusion. On color Doppler the closure rates at 24 h and 1 month after implant were 66% and 97%, respectively. At 6 and 12 months all except one patient attained complete occlusion. Device embolization occurred in three patients; in two this was spontaneous, and in the other it was due to catheter manipulation during postimplant hemodynamic measurement. Mild aortic narrowing was seen in an infant. CONCLUSIONS: Patent ductus arteriosus occlusion using ADO is safe and efficacious. It is particularly useful in symptomatic infants and small children with relatively large PDA. Embolization can be minimized by selection of appropriate sized devices, and caution should be exercised in infants <5 kg. 相似文献
13.
BACKGROUND: Surgical closure of patent ductus arteriosus in adult patients may be problematic. Transcatheter closure of patent ductus arteriosus is an established procedure. Recently, transcatheter closure of patent ductus arteriosus using the Amplatzer duct occluder has been shown to be safe and efficacious. We present our experience with this device in adults. METHODS AND RESULTS: Between January 2000 and January 2002,41 adult patients (31 females and 10 males) with a patent ductus arteriosus were referred for closure with the Amplatzer duct occluder. The median age was 35.6 years (range 18-70.7 years) and the median weight was 65.8 kg (range 32.7-164.5 kg). Of these 41 patients, 37 underwent attempted closure of the patent ductus arteriosus using the Amplatzer duct occluder. The device was successfully deployed in all patients except 1. Complete angiographic closure was seen Immediately after device deployment in 29 out of 36 patients (81%). Complete echocardiographic closure was demonstrated within 24 hours post-procedure in 34 out of 36 patients (94%), and at 6-month follow-up in 35 out of 36 patients (97%). No complications related to device implantation occurred in any patient. CONCLUSIONS: Closure of patent ductus arteriosus using the Amplatzer duct occluder is safe and effective in adults. 相似文献
14.
Koch A Hofbeck M Buheitel G Gerling S Rauch R Singer H 《Zeitschrift für Kardiologie》2001,90(2):120-126
This report describes our results with transcatheter closure of patent ductus arteriosus between March 1993 and May 2000 including our early experience with the Amplatzer duct occluder. One hundred and sixty-six consecutive procedures were performed in 160 patients. The mean age was 6.8 years (range 0.8 to 26.2), mean weight 24.3 kg (range 7.7 to 84.0). Single or multiple coils were implanted successfully in 114 cases, a Rashind double umbrella in 35 patients, and an Amplatzer duct occluder in 16 patients. After failure to implant coils in one patient, a second attempt with a Rashkind double umbrella was successful. Complete closure of the patent ductus arteriosus was achieved in a total of 148 patients (92.5%), mean fluoroscopy time was 13.7 min (range 3.1 to 126 min). In 144 patients (90.0%), occlusion without residual shunting was achieved by the first interventional approach. Angiography showed immediate closure in 44%, echocardiography within 48 h revealed complete closure in additional 28%. In a further 18%, a residual shunt disappeared spontaneously in the following months. In five patients a second procedure was performed to terminate residual shunting after placement of a Rashkind occluder system by coils. In three patients, the residual shunt resolved. In 12 patients (7.5%) echocardiography showed a residual shunt 2-1259 days after interventional approach. Occlusion rates of the different devices were 83% for the Rashkind occluder, 92% for detachable coils, and 100% for the Amplatzer duct occluder. Coil embolisation into the pulmonary artery occurred in two patients, interventional removal was successful in one of them. There were no further complications. According to our experience interventional occlusion of patent ductus arteriosus is highly effective and associated with a low complication rate. Transcatheter closure using the Amplatzer duct occluder seems to be safe and effective also in small children with a body weight of 8 kg and a large ductus diameter. Compared to the total group of patients, the occlusion rate of the Amplatzer duct occluder was significantly higher (p = 0.005), and of the Rashkind occluder system significantly lower (p = 0.026). Therefore, we recommend the use of detachable coils in patients with small ductus (diameter < or = 2 mm) and the Amplatzer duct occluder in those with a larger ductus. Transcatheter closure of the patent ductus arteriosus according to this regimen should achieve occlusion rates above 95%. 相似文献
15.
Alexander J Javois Tarek S Husayni David Thoele Andrew H Van Bergen 《Catheterization and cardiovascular interventions》2006,67(3):485-489
We report a 12-month old patient who presented for murmur evaluation after percutaneous closure of type C patent ductus arteriosus (PDA) using a 10 mm Amplatzer Vascular Plug (AGA Medical Corporation, Golden Valley, MN) at an outside institution. Echocardiography revealed a large left-to-right shunt through the implanted device, inadvertently stenting the PDA instead of closing it. The patient underwent repeat catheterization with successful coil implantation within the Amplatzer Vascular Plug, completely eliminating the large residual ductal shunt. Although challenging, this case illustrates the technique of implanting coils within this occlusion device. This case also illustrates that occlusion of type C PDA utilizing the Amplatzer Vascular Plug may not only result in incomplete occlusion but also create a potentially worse clinical situation in which the PDA is stretched larger and stented open. Without consideration of simultaneous coil implantation within this device, use of the Amplatzer Vascular Plug might be contraindicated in type C PDA, because there may be no way to ensure successful closure by the Vascular Plug alone. 相似文献
16.
Transcatheter closure of moderate to large patent ductus arteriosus with the Amplatzer duct occluder. 总被引:2,自引:0,他引:2
Jou-Kou Wang Mei-Hwan Wu Juey-Jen Hwang Fu-Tein Chiang Ming-Tai Lin Hung-Chi Lue 《Catheterization and cardiovascular interventions》2007,69(4):572-578
OBJECTIVES: To investigate the acute and follow-up results of transcatheter closure of moderate to large patent ductus arteriosus (PDA) with the Amplatzer duct occluder. METHODS: Between April 2000 and June 2005, 237 patients underwent attempted transcatheter closure of PDA, of whom Amplatzer duct occluder was used in 68 patients with moderate-to-large-sized PDA (45 females, with ages ranging from 56 days to 75 years, median 3.3 years). Moderate to large PDA is defined as ductus diameter > or =2.5 mm (> or =3 mm in early phase of this study) in infants and young children, or > or =4 mm in adolescents and adults. The size of device selected was generally at least 1-2 mm larger than ductus diameter. RESULTS: The ductus diameter ranged from 2.5 to 8.5 mm (4.1 +/- 1.3 mm). Amplatzer duct occluder was successfully deployed in 66 out of 68 patients. The size of device deployed ranged from 4 to 12 mm (6.3 +/- 1.6 mm). The causes of failure in the 2 patients included calcification of ductus resulting, in failure in advancing a sheath to descending aorta in 1 and kinking of a Cook sheath in the other. Distal embolization of the device occurred several hours later in one. After the device was retrieved percutaneously, the patient was sent to surgery. No other significant complications occurred. In the 3-month follow-up, complete occlusion was achieved in all patients. No patient had left pulmonary artery stenosis. CONCLUSIONS: Transcatheter closure of moderate-to-large-sized ductus with Amplatzer ductus occluder is effective and safe. 相似文献
17.
Comparison and results of transcatheter closure of patent ductus arteriosus using the swivel-disk device versus plug occluder in children 总被引:1,自引:0,他引:1
Thanopoulos BV Tzannos KA Eleptherakis N Stefanadis C 《The American journal of cardiology》2008,102(4):486-490
The transcatheter closure of certain types of patent ductus arteriosus (PDA) remains a challenge. The investigators report initial clinical experience with 25 patients who underwent PDA occlusion with the use of a swivel-disk device (SDD) or a plug occluder (PO). The patients were divided into 2 groups: in the SDD group, 12 patients aged 1 to 2 years with type A PDA underwent attempted closure using the SDD, a modified Amplatzer duct occluder with a very low profile retention disk that can adapt itself at different PDA insertion angles. The mean PDA diameter was 4.8 +/- 1.5 mm (range 3.8 to 8). In the PO group, 13 patients aged 0.5 to 3 years with type C, D, or E PDA underwent attempted occlusion with the PO, a tubular occluder made of Nitinol wire mesh. The mean PDA diameter was 4.2 +/- 3.5 mm (range 1.2 to 9). The 2 occluders are filled with Dacron patches. The mean device diameters were 6.5 +/- 1.2 and 6.8 +/- 2.2 mm (range 4 to 11) in the SDD and PO groups, respectively. Complete angiographic closure was seen in 24 of 25 patients. The deployment of 4 5-PDA5 coils abolished a residual shunt associated with hemolysis in a 5-month-old patient with a large type C PDA after the implantation of an 11-mm PO. No other complications were observed. In conclusion, the SDD and the PO are promising additions to the armamentarium for PDA closure. 相似文献
18.
Transcatheter closure of patent ductus arteriosus with the Amplatzer duct occluder: short-term follow-up 总被引:1,自引:0,他引:1
Sandhu SK King TD Troutman WB Hixon RL Kiel EA Bourgeois KV 《The Journal of invasive cardiology》2001,13(4):298-302
BACKGROUND: Transcatheter closure of the patent ductus arteriosus is a well established procedure. The objective of this study was to assess the effectiveness and the safety of the Amplatzer duct occluder. METHODS AND RESULTS: Occlusion of the patent ductus arteriosus was attempted in 23 patients. The median weight was 11.7 Kg (range, 5 kg - 42.4 kg) with a mean ductus diameter of 3.7 mm (range, 1.6 - 7.2 mm). The immediate closure rate was 86% with a closure rate of 100% at 6 months, 1 year and 2 years following device placement. There was one device embolization that occurred immediately following device placement. No patient had aortic narrowing or pulmonary artery stenosis following the procedure. CONCLUSIONS: The Amplatzer duct occluder is safe and effective in the closure of a patent ductus arteriosus up to 7.2 mm in diameter. Selecting a device at least 12 mm larger than the minimal ductal diameter can minimize embolization. 相似文献