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1.
Cataracts induced by atopic dermatitis rarely occur in adolescent and young adult patients suffering from this problem. Lenticular opacity is an important ocular complication in atopic dermatitis. Although the cause of atopic dermatitis and its ocular complications are unknown, cataracts have been observed to develop and progress during periods of exacerbation of the dermatitis. We report the case of a 16-year-old boy with atopic dermatitis who abruptly developed cataracts in both eyes while suffering from severe skin itching which began 2 months before the initial examination. His peroxidation test result was very high, and we postulate the retinal peroxidation might play a key role in cataractogenesis. Lens aspiration and intraocular artificial lens implantation were performed smoothly with restoration of visual acuity in both eyes.  相似文献   

2.
目的评价高度近视白内障摘除及人工晶体植入术的临床疗效 .方法对眼轴长 >2 6mm的 39例 (43只眼 )高度近视并发白内障患者 ,施行白内障摘除及人工晶体植入术 .结果平均随访 2 4个月 (12~ 48个月 ) ,眼轴2 6~ 2 8mm 2 5只眼 ,术后矫正视力 >0 5的 2 2只眼 ,占 88% ,眼轴长 >2 8mm 18只眼 ,术后矫正视力 >0 5的 4只眼 ,仅占 2 2 % .术后未见视网膜脱离、青光眼、角膜营养不良等并发症 .结论高度近视眼白内障行人工晶体植入术 ,安全可靠 ,手术并发症少 .视力差的主要原因为眼底病变 ,并随眼轴长增加而增加 .  相似文献   

3.
目的评价玻璃体切除联合白内障手术治疗增殖性糖尿病视网膜病变(proliferative diabetic retinopathy,PDR)的临床效果。方法回顾性分析了2005年7月至2009年12月在我院行玻璃体切除联合白内障手术的PDR患者48例(52眼),术后随访7个月以上,统计分析手术方式、术前、术后最终矫正视力、手术并发症等临床资料。结果硅油填充率随着糖尿病眼底病变发展而增加,VI期硅油填充率分别与IV期、V期相比差异显著,P〈0.01;随访期间,71.15%(37/52)术后视力提高,随着糖尿病眼底病变发展,术后视力提高率下降,IV、V、VI期术后视力提高率分别是100%、92.31%和62.16%,但各组间无显著差异,P〉0.05,其中视力0.1以上的眼数由术前的5眼(11.36%)增加到术后的33眼(75%),术后视力显著好于术前,P〈0.01;一次性视网膜复位成功率100%。1眼术后玻璃体再次出血,7眼发生后发性白内障,硅油填充组6眼术后早期发生高眼压,4眼在术后不同时期发生硅油乳化。结论玻璃体切除联合白内障手术治疗PDR是安全有效的,有利于早期恢复患者视力,避免再次白内障手术。  相似文献   

4.
Purpose: To evaluate the safety and efficacy of implantation of a capsular tension ring (CTR) and posterior chamber intraocular lens (PCIOL) after lens extraction in subluxated cataracts. Setting: Department of Ophthalmology,General Hospital of PLA, Beijing, China. Design: Prospective case series. Methods: We selected 36 eyes in 34 patients with zonular dialysis <150°. After emulsification and removal of the residual cortex, we inserted a CTR into the capsular bag to center the PCIOL. We measured preoperative and postoperative best corrected visual acuity (BCVA), centration of the CTR and IOL, and perioperative complications. Results: No capsule collapseor fluctuationof the anterior chamber occurred. Most eyes (63.89%) had nuclear sclerosis of ≥3+. A CTR was implanted into the capsular bag without extension of zonular dialysis. A traumatic subluxated cataract was the most common cause (20 of 36 [55.56%]). We found a subluxated cataract in 3 eyes (3 of 36 [8.33%]) with previous acute angle-closure glaucoma. Mean follow up was 20.3±2.4 months. Preoperatively, only 5 eyes (13.89%) had a BCVA of ≥20/40, compared with 30eyes at the last visit (83.33%, P<.001). Improved BCVA was achieved in 33 eyes (91.7%) in week 1, and visual acuity remained stable up to 1 year. The CTRs with PCIOL were well centered at 1 year. Conclusion: In patients with a subluxated hard cataract <120°, CTR implantation should be performed after lens extraction without extension of zonular dialysis and capsular destabilization. Maintaining anterior chamber depth and avoiding capsular bag collapse are critical.  相似文献   

5.
Phacoemulsification and implantation of a foldable intraocular lens for cataract is almost a routine procedure in ophthalmic practice. Late postoperative opacification of hydrophilic acrylic (hydrogel) intraocular lenses (IOLs) has been reported, but the appearance differs from our findings. We report clinical, pathologic, ultrastructural, and spectroscopic analyses of foldable hydrogel IOLs undergoing late opacification resulting in visual disturbances. This retrospective study comprised 486 patients (550 eyes) who had implantation of a foldable hydrogel posterior IOL. Three cases (three eyes) had been found to have opacification of the IOLs. The three lenses were exchanged because of significant visual disturbances, and were examined using light microscopy, scanning electron microscopy and energy dispersion X-ray (EDX) spectroscopy. Incisional biopsies of the capsular membrane in contact with the opacified IOL were performed in one patient. The mean interval between implantation of the hydrogel IOLs and the diagnosis of opacification was 35.3 months (range, 34-36 months). All three of the cases had quiet anterior chamber. No obvious posterior capsular opacification were found. The best corrected visual acuity of the three cases who had exchanged IOLs were all 20/25 or better. Microscopic analysis revealed multiple, fine, granular structures both on the surface and matrix of the opacified IOLs. EDX analysis showed the presence of calcium and phosphorous were within the granular structures. Histological examination of capsular membrane did not reveal any evidence of calcium salts or special pathological exchanges. Further studies should be undertaken to determine the incidence and possible mechanisms of this phenomenon.  相似文献   

6.
目的 探讨对白内障病人实施小切口非超声乳化摘除联合人工晶体植入术的临床疗效.方法 对50例(55眼)白内障病人实施小切口非超声乳化白内障摘除联合人工晶体植入术,观察病人术前、术后视力变化.结果 在术后3日、1周及1个月时病人裸眼或矫正视力≥0.5者分别占70.91%(39/55)、81.82% (45/55)、89.09% (49/55).6例病人视力低于0.5为视网膜病变者.术后未见巩膜隧道切口渗漏现象,外切口在1周内覆盖结膜上皮,无悬韧带断裂与后囊破裂,瞳孔均呈现出圆形或近圆形.结论 该治疗方法具有创伤小、手术安全、疗效确切、视力恢复速度快,不良反应少.可作为治疗白内障的微创手术推广应用.  相似文献   

7.
To report a patient who presented with epithelial ingrowth caused by viral keratoconjunctivitis 3 months after LASIK surgery. A 41-year-old man presented with decreased visual acuity in the right eye, which had developed about 3 weeks before. He had undergone LASIK surgery 3 months prior without complications. Two months after the surgery, he was treated for viral conjunctivitis. During the treatment period, filamentary keratitis developed, and a therapeutic bandage contact lens was applied for 2 weeks. Upon presentation, examination revealed a corrected visual acuity of 20/100 and irregular epithelial sheets under the edematous flap. The flap was lifted, and the in-grown epithelium was removed. The flap was repositioned with double continuous 10-0 nylon sutures. Post-operatively, the patient developed a mild diffuse lamellar keratitis that resolved rapidly with topical corticosteroid treatment. At 2 months, the corrected visual acuity was 20/20 without interface opacities. As the patient showed no complications prior to viral conjunctivitis, we suspect that the viral infection caused edema of the corneal flap, which caused epithelial ingrowth under the flap. Patients who have viral conjunctivitis after LASIK surgery should be examined carefully and managed with consideration of flap complications.  相似文献   

8.
Thetrendofthemorderncataractsurgeryis:smalincision,phacomulsfication,IOLimplantedinthecapsulebag〔1,2〕.BesidesthefoldableIOLs〔...  相似文献   

9.
刘姣  赵敏 《中国组织工程研究》2012,16(38):7211-7215
背景:有关人工晶体植入眼与正常眼对比敏感度视力的比较还少见报道。 目的:比较人工晶体植入眼与正常眼不同对比敏感度下的视功能。 方法:实验组选择白内障超声乳化摘除并植入人工晶体且随访资料完整的病例25例(41眼),对照组选择年龄、性别与实验组相匹配的正常人18例(31眼)。在最佳远校正状态下采用多功能电子视力测量仪测试两组亮暗环境下不同对比敏感度(100%,25%,10%,5%)视标的LogMAR视力。 结果与结论:①亮背景:随着对比敏感度的下降,两组视功能均逐渐下降。在100%,25%,10%对比敏感度下,两组LogMAR视力均无差异(P > 0.05),在5%对比度下,实验组LogMAR视力低于对照组(P < 0.05)。②暗背景:随着对比敏感度的下降,两组视功能均逐渐下降。在100%,25%对比度下,两组LogMAR视力无差异(P > 0.05),在10%和5%对比敏感度下,实验组LogMAR视力低于对照组(P < 0.05,P < 0.01)。③同一对比敏感度时,亮暗背景下两组视力无差异。表明无论亮暗环境在低对比敏感度下人工晶体眼的视力均低于正常眼,且对比敏感度越低差异越明显;环境亮度对视力的影响较对比敏感度低。  相似文献   

10.
赵向阳  李卫平刘辉 《医学信息》2005,18(10):1345-1347
目的 评价小光斑飞点扫描式准分子激光系统用于准分子激光原位角膜磨镶术治疗远视的有效性、预测性和安全性。方法 采用Keracor217z准分子激光机对27例48眼远视患者(+1.50-+6.00D),行准分子激光角膜原位磨镶术,术后随访6个月。结果 术后6个月时,最佳矫正视力与术前相比,未见视力下降超过1行以上者,91.6%的患者裸眼视力达到0.5以上,100%的患者裸眼近视力达到0.5以上,术中术后无严重并发症。结论 小光斑飞点扫描式准分子激光系统治疗远视的临床效果较好,大大减少了手术并发症的发生率。  相似文献   

11.
BACKGROUND: More than 250 cases of allergic contact dermatitis due to propolis have been described. A few of these occurred in beekeepers. OBJECTIVE: To describe a case of psoriasiform dermatitis caused by propolis in a beekeeper who thought that his lesions were related to honeybee stings. METHODS: A 45-year-old beekeeper experienced hand dermatitis for the past 5 years. He believed that the lesions occurred and worsened when he was stung by honeybees. He was prescribed topical corticosteroids several times, but because he was stung frequently, the drugs never helped control the lesions. In the past few years, he frequently had contact with propolis during honey collection, but he denied the role of propolis because he was wearing gloves while handling the beehives. For diagnostic evaluation, skin biopsy, skin prick tests (SPTs), identification of specific IgE antibodies, and atopic patch tests were performed. RESULTS: Skin biopsy showed psoriasiform contact dermatitis. Results of SPTs to honeybee and serum specific IgE for Apis mellifera remained negative. Results of the atopic patch test performed using A mellifera SPT material were also negative in the first 20 minutes and on the second and third days. However, propolis showed a positive erythematopapular reaction on day 2. The patient never again worked as a beekeeper, and neither did he, as far as he knew, use any medical or cosmetic products that contained propolis. His hand lesions improved almost completely. CONCLUSION: Dermatitis due to propolis should never be disregarded in beekeepers, and every effort should be put forth to make a correct diagnosis and to convince the patients of the cause.  相似文献   

12.
PurposeTo analyze long-term visual outcomes and complications of the implantation of a scleralfixated posterior chamber intraocular lens (PC-IOL) in patients with the lack of adequate capsular support, and to verify if the procedure can be performed with 9-0 polypropylene sutures.MethodsThe study was designed as a long-term retrospective analysis. Patients after the implantation of a scleralfixated PC-IOL were evaluated for the best corrected visual acuity (BCVA), intraocular pressure and occurrence of postoperative complications.ResultsThe analysis included 29 eyes from 28 patients. Indications for the IOL implantation included ocular trauma (89.7%) and previous complicated cataract surgery (10.3%). A postoperative improvement of BCVA was observed in 25 eyes (86.2%). Mean follow-up time was 63.9 months (range 50–83 months). During this time, six patients (21.4%) were diagnosed with glaucoma (21.4%), and retinal detachment was found in one eye (3.4%). A total of six suture breakages were recorded in four eyes from four patients (13.8%); one breakage was precipitated by a trauma, and another five, involving three eyes from three patients, were spontaneous. Mean time to the spontaneous suture breakage was 40.8 months.ConclusionsScleral fixation of the PC-IOL provides satisfactory visual outcomes. However, this procedure is associated with a considerable risk of postoperative complications. The incidence of postoperative suture breakage in our series was similar as in previous studies in which the PC-IOL was fixated with 10-0 polypropylene suture. A superiority of 9-0 polypropylene suture needs to be verified in larger series of consecutive patients.  相似文献   

13.
背景:传统深板层角膜移植治疗圆锥角膜后弹力层穿孔率较高。 目的:观察改良深板层角膜移植治疗圆锥角膜后屈光状态的长期改变及相关因素分析。 方法:采用改良深板层角膜移植法治疗46例(51眼)圆锥角膜患者,记录移植前后裸眼视力和最佳矫正视力;移植前按平均角膜曲率大小分为两组,平均角膜曲率≥60 m-1组与<60 m-1组,观察移植后24个月的等效球镜、散光、角膜曲率,并分析眼轴与术后屈光状态的相关性。 结果与结论:与移植前比较,移植后1,6,12,18,24个月的裸眼视力及最佳矫正视力均有显著提高(P < 0.01或P < 0.05),移植后6个月内视力是显著提高的,6~18个月视力虽有一定的提高,但基本是处于稳定的趋势,18~24个月视力显著提高,显示随 着移植后时间的延长,视力逐渐提高并趋于稳定,说明改良深板层角膜移植后长期疗效佳。两组移植后的等效球镜、移植后散光、平均角膜曲率均较移植前明显改善,但两组间差异均无显著性意义(P > 0.05),眼轴与移植后的等效球镜、裸眼视力、角膜散光有一定的负相关性。说明改良深板层角膜移植后等效球镜向近视方向移动,角膜散光逐渐减小,平均角膜曲率逐渐增大。移植前角膜曲率差异对改良深板层角膜移植后屈光状态无明显影响。眼轴与术后屈光状态有一定的相关性。  相似文献   

14.
目的通过双切口行白内障超声乳化联合小梁切除术治疗青光眼和白内障,观察患者手术前后视力、眼压改变及术后并发症情况。方法选取我院自2010年1月至2013年12月青光眼合并白内障患者60例(78眼),将双切口行白内障超声乳化联合小梁切除病例32例(40眼)作为观察组,另外28例(38眼)行白内障超声乳化手术作为对照组,观察2组患者手术前后视力、眼压及前房情况,并随访3~6个月。结果 2组患者手术后视力均有明显提高,眼压有明显改善,但观察组更显著,P0.05,差异有统计学意义。观察组患者前房出现不同的炎症反应,有2例发生前房渗出,对照组前房炎症反应稍轻;2组患者无前房出血、浅前房、脉络膜脱离等发生。结论采用双切口行青光眼白内障联合手术后视力恢复好,眼压控制满意;虽然术后前房反应稍重,但用药后很快缓解,减少了患者多次手术的痛苦及经济负担,但要严格选择病例。  相似文献   

15.
Two schizophrenic patients who had been taking medication for a long period presented with visual disturbance of 6-month duration. Slit-lamp examination revealed fine, discrete, and brownish deposits on the posterior cornea. In addition, bilateral star-shaped anterior subcapsular lens opacities, which were dense, dust-like granular deposits, were noted. Although we strongly suspected that the patient might have taken one of the drugs of the phenothiazine family, we were unable to obtain a history of medications other than haloperidol and risperidone, which were taken for 3 yr. We performed a drug profiling test using urine samples and detected methotrimeprazine. The patient underwent surgery for anterior subcapsular lens opacities. Visual acuity improved in both eyes, but the corneal deposits remained. We report an unusual case of methotrimeprazine-induced corneal deposits and cataract in a patient with psychosis, identified by using the urine drug profiling test.  相似文献   

16.
We report the successful removal of a retrobulbar foreign body using a transcranial approach in a 63-year-old patient with a penetrating injury to the left eye. Initial ocular examination revealed a corneoscleral laceration, hyphema, a traumatic cataract, and vitreous hemorrhage. Visual acuity consisted only of the perception of hand motion. Computed tomography demonstrated an orbital foreign body in the retrobulbar area. Emergency corneoscleral suturing, phacoemulsification of the cataract, and vitrectomy with posterior vitreous detachment were performed. Fifteen days after the emergency operation, we successfully removed the orbital foreign body using a transcranial approach, although the foreign body was very close to the optic nerve. On fundus examination 6 months later, a white, fibrous lesion was seen inferior to the optic disc, and the corrected visual acuity was 20/30. These positive results may be due to the complete vitrectomy at the correct time performed by a retina specialist and the minimal pressure on the eyeball while removing the foreign body, which resulted from the use of a transcranial approach.  相似文献   

17.
文题释义: 超声乳化:是指在超声波能量作用下,使2种(或2种以上)不相溶液体混合均匀形成分散物系,其中一种液体均匀分布在另一液体之中而形成乳状液的工艺过程。 眼内压:指眼球内的眼内液的压力,因此仅能用流体压力计测定。 背景:白内障伴青光眼患者经超声乳化联合小梁切除治疗后,血脂比和胰岛素敏感性与其眼内压、视力和角膜内皮细胞等疗效相关指标均相关,可能用于其疗效的辅助评估。白细胞介素是机体内炎症反应的主要参与者和调解者,且参与了白内障的病理学过程。 目的:试验将从炎性因子角度,进一步观察白内障伴青光眼患者术后炎性因子白细胞介素10、白细胞介素2及白细胞介素10水平变化,分析胰岛素敏感性与角膜内皮细胞密度的相关性,以了解其是否可用于疗效评估。 方法:此项目设计为前瞻性、单中心、开放性、自身对照研究。拟纳入来自中国云南省,昆明医科大学第一附属医院眼科的白内障伴青光眼患者160例,年龄35-65岁,均进行超声乳化联合小梁切除治疗,随访时间为术后5 d及术后1,3个月。试验资料收集和招募对象时间为2019-12-30/2020-12-30,结果分析时间为2021-05-01/30,试验完成时间为2021-06-30。试验经昆明医科大学第一附属医院医学伦理委员会批准(审批时间:2013-12-15,审批号:20131215085)。研究符合世界医学会制定的《赫尔辛基宣言》的要求,患者均签署知情同意书。试验已在中国临床试验注册中心注册(注册号:ChiCTR1900025837),注册时间:2019-09-10,方案版本号1.0。 结果与结论:试验的主要结局指标为术后3个月反映炎性反应情况的血清白细胞介素2水平变化;次要结局指标为术前、术后5 d及1个月血清白细胞介素2水平,术前、术后5 d及术后1,3个月血清白细胞介素1β、白细胞介素10、C-反应蛋白、肿瘤坏死因子α水平、最佳矫正视力、内皮细胞密度、平均细胞面积、面积变异系数、胰岛素敏感指数及眼内压变化,术后5 d及术后1,3个月的不良反应发生率变化。课题组已于2014年1月至2017年6月完成了80例(95眼)白内障伴青光眼患者以此方法干预的小样本试验,结果显示,超声乳化联合小梁切除术治疗后最佳矫正视力明显改善,内皮细胞密度,眼内压及白细胞介素白细胞介素1β、白细胞介素2、白细胞介素10、C-反应蛋白及肿瘤坏死因子α水平明显降低(P < 0.05),而平均细胞面积和面积变异系数及胰岛素敏感指数明显升高(P < 0.05),所有患者在治疗过程中均无明显不良反应。试验期望验证,超声乳化联合小梁切除对白内障伴青光眼有良好治疗效果,且其作用与调节胰岛素敏感指数、角膜内皮细胞和炎症因子有关。 ORCID: 0000-0001-8388-5374(赵剑峰) 中国组织工程研究杂志出版内容重点:组织构建;骨细胞;软骨细胞;细胞培养;成纤维细胞;血管内皮细胞;骨质疏松;组织工程  相似文献   

18.
目的探讨LASIK手术治疗儿童屈光参差的疗效。方法通过回顾性分析30例屈光参差患儿实施LASIK手术前与手术后不同时间视力、屈光度、眼轴、双眼视觉、VEP等视功能参数的变化,了解LASIK手术的疗效。结果近视组手术后裸眼视力有明显提高(P〈0.05),达到了术前最佳矫正视力;屈光度完全矫正;术后三级视功能明显改善。远视组手术后屈光度与三级视功能均有显著改善(P〈0.01),而裸眼视力与矫正视力,视觉诱发电位均无明显改善(P〉0.05)。两组手术前后眼轴无明显增长(P〉0.05)。结论LASIK手术矫治儿童屈光参差,能降低高屈光度眼的屈光力、缩小双眼屈光度的差别,利于双眼融像。  相似文献   

19.
BACKGROUND: Atopic dermatitis often has an allergic component, and immunotherapy may therefore prove beneficial. OBJECTIVE: To assess the effect of sublingual immunotherapy (SLIT) in children with atopic dermatitis. METHODS: Children age 5 to 16 years with atopic dermatitis (Scoring Atopic Dermatitis [SCORAD] > 7) and sensitization to dust mites alone, without food allergy or chronic asthma, were enrolled in a randomized, double-blind, placebo-controlled study and stratified according to disease severity. SLIT or placebo was given for 18 months in addition to standard therapy. SCORAD, visual analog scale, and rescue medication consumption were recorded at 3-month intervals. RESULTS: Fifty-six children were enrolled, and 28 were allocated to SLIT. Forty-eight completed the study, with 2 dropouts in the active and 6 in the placebo group. The difference from baseline in the SCORAD was significant (P = .025) between the 2 groups starting from month 9. Similarly, there was a significant reduction in the use of medications only in the active group. A trend toward significance was seen for the visual analog score only in the active group versus baseline (P = .07). A significant difference in the considered parameters was found only in patients with a mild-moderate disease, whereas severe patients had only a marginal benefit. SLIT had to be discontinued in 2 patients because of exacerbation of dermatitis. CONCLUSION: Sublingual immunotherapy to dust mite improves mild-moderate atopic dermatitis. CLINICAL IMPLICATIONS: Sublingual immunotherapy may represent an additional therapeutic tool for the treatment of extrinsic atopic dermatitis in properly selected children.  相似文献   

20.
This is a review of the major publications from the Nigeria national blindness survey in order to highlight major findings and challenges of eye care in Nigeria. The review summarizes methodology and key findings. Survey publications on methodology, prevalence and causes of visual impairment and outcome of cataract surgery were retrieved, reviewed and relevant data extracted, reported and discussed. The study was the largest and more detailed eye survey in Nigeria (15,375 people 40 years and older recruited). Participants had detailed eye examination including visual acuity, autorefractokeratometry, A- scan biometry, visual field and basic eye examination. Cause(s) of visual impairment in each eye using WHO algorithm was determined among participants with vision < 6/12. Some of the participants also had qualitative questions on barriers to uptake of services, quality of life and visual function. Major highlights of the results as contained in the publications include a high prevalence of blindness with 4.2% (95% CI: 3.8-4.6%;),of the study population having blindness (using presenting vision (PVA)) even with best correction the prevalence was 3.4% (95% CI: 3.0-3.8%. The prevalence of SVI using PVA was 1.5% (95% CI: 1.3-1.7%).and with best correction 0.8% (95% CI: 0.7-1.0%). Blindness varied by age groups, sex, literacy level and geopolitical zone. Furthermore, 84% of blindness was due to avoidable causes with cataract responsible for 43% of blindness, glaucoma 16.7%, uncorrected aphakia 8.4% and corneal opacity 7.9%. Of the total 538 eyes that had cataract surgery procedures, 42.7% had couching and the remaining had cataract surgery, but only 41.4% of cataract operated eyes had IOL surgery. Outcome of cataract surgery was good at presentation for only 30.8% of eyes (84 eyes) which improved to 56.8% with correction. The possible remedy for the high burden of needless blindness and harmful eye health practices in Nigeria are discussed.  相似文献   

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