新型冠状病毒肺炎疫情期间眼科手术安全性及防控对策

目的:探讨新型冠状病毒肺炎疫情期间开展眼科手术的安全性,并提出相关防控对策。方法:收集2020年1月25日至2020年2月28日新型冠状病毒肺炎疫情期间,在天津医科大学总医院眼科接受手术治疗者11例(12眼)的资料。其中眼球破裂,角膜穿孔伤,角膜穿孔伤合并外伤性白内障,眼内异物各1例(1眼),泪小管断裂2例(2眼),孔源性视网膜脱离4例(4眼),青光眼1例(2眼)。所有患者进行体温监测和流行病学调查。按照国家疫情防控要求和医院的应急管理流程,制订了眼科诊疗流程,所有患者均严格按照此流程进行管理,围手术期严格监测体温、呼吸道等全身情况。结果:11名患者就诊前行体温监测、流行病学调查、临床及影像学检查均正常,并请感染科专家会诊排除新型冠状病毒肺炎。所有患者均为眼外伤和急性眼病,包括急诊手术6眼,限期手术6眼,严格遵照眼科诊疗流程进行手术治疗,术后恢复良好,均未出现严重手术并发症。住院及随访期间患者、家属及医护人员均未发生新型冠状病毒肺炎。结论:新型冠状病毒肺炎疫情期间严格筛查患者,严格按照疫情期间防控工作流程要求,眼科手术是安全可行的。     

眼科门诊应对新型冠状病毒肺炎的管理实践

简述眼科门诊在新型冠状病毒肺炎疫情期间的管理措施。从预约就诊、预检分诊、分区管理、眼外伤等急症患者就诊处置和健康宣教方面进行门诊防控管理,同时加强医务人员防护,设备清洁消毒。希望为眼科医务工作者在新型冠状病毒肺炎疫情期,避免医患之间及患者与患者之间交叉感染提供新思路、新方法。     

新型冠状病毒肺炎疫情期间眼科急诊及手术的防控策略

新型冠状病毒(SARS-CoV-2)感染的肺炎,新型冠状病毒肺炎(COVID-19)已被中国列为按照甲类传染病管理的乙类传染病,由医院相关性传播导致的COVID-19并不少见,给临床医护人员和住院患者造成严重威胁。本文介绍眼科医生应掌握COVID-19的流行病学特点和临床表现,眼科医生如何应对眼科急诊患者,围绕眼科急诊及手术的感染防控要点和加强具体防控措施,为战疫在一线的眼科医护感染防控提供参考。     

新型冠状病毒肺炎疫情下眼科急诊感染防控管理的体会

目的总结新型冠状病毒肺炎(COVID-19)疫情下专科医院眼科急诊有效的感染防控措施。方法 2020年1月24日起从人员管理(包括医务人员和患者)、科室硬件环境、眼科器械消毒、病毒管理上报制度等方面着手,对新型冠状病毒(2019-nCoV)感染途径进行严格把控。结果共接诊1 936例眼科急诊患者(比去年同期增长21.7%),完成急诊工作的同时,所有医护人员在疫情期间无因工作原因导致2019-nCoV感染。结论思想重视、措施到位、严格把控,能够有效防范眼科医护人员感染2019-nCoV。     

新型冠状病毒肺炎疫情期间急诊眼外伤疾病谱特点及流行病学分析

目的 分析新型冠状病毒肺炎疫情期间眼科急诊眼外伤疾病谱变化趋势及流行病学特点。设计 回顾性比较性病例系列。研究对象 以2020年1月23日至3月31日北京同仁医院眼科急诊就诊的1209例眼外伤患者作为研究组,以2019年同期就诊的2444例眼外伤患者作为对照组。方法 通过医院信息系统调取数据,登记并整理患者的年龄、性别、就诊时间、眼外伤类别、致伤部位、就诊数量等情况,对眼外伤急诊疾病谱变化及流行病学特点进行分析。主要指标 年龄、性别、就诊时间、急诊诊断、患者数量。结果 疫情期间眼科急诊患者总数5978例,眼外伤患者1209例,占20.2%;2019年同期眼科急诊患者总数12776例,眼外伤患者2444例,占19.1%（χ2=3.111,P=0.078）。研究组男性患者835例（69.1%）,对照组男性患者1743例（71.3%）（χ2=1.976,P=0.160）。研究组患者年龄37.0（26.5,52.0）岁,对照组患者年龄35.0（22.0,50.0）岁（U=1369248.50,P＜0.001）。两组间各年龄组的就诊患者均以青年组（18~44岁）占比最高（研究组561例,46.4%;对照组1090例,44.6%）（χ2=1.062,P=0.303）;未成年组（0~17岁）患者就诊例数及比例的差异有统计学意义（研究组199例,16.5%;对照组548例,22.4%）（χ2=17.854,P＜0.001）。疫情期间非机械性眼外伤患者例数增多,其中电光性眼炎患者较去年同期明显增多（研究组141例,81.0%;对照组53例,46.9%）（χ2=36.437,P＜0.001）。机械性眼外伤患者较去年同期明显下降（研究组1035例,85.6%;对照组2331例,95.4%）（χ2=106.619,P＜0.001）。机械性眼外伤最常累及眼睑（研究组599例,57.9%;对照组1351例,58.0%）（χ2=0.002,P=0.964）;研究组的结膜损伤较对照组增多（研究组213例,20.6%;对照组336例,14.4%）（χ2=19.959,P＜0.001）;葡萄膜损伤较去年同期减少（研究组39例,3.8%;对照组131例,5.6%）（χ2=5.125,P=0.024）;开放性眼外伤所占比例的差异无统计学意义（研究组101例,9.8%;对照组193例,8.3%）（χ2=1.966,P=0.161）。结论 新型冠状病毒肺炎疫情期间眼科急诊总量及眼外伤急诊量明显下降。男性、青年、未成年人仍是急诊眼外伤的高发人群,未成年人发病率较去年同期下降。电光性眼炎患者明显增多,机械性眼外伤患者明显下降。     

新型冠状病毒肺炎疫情下眼科诊疗工作的风险及防护分析

目前,眼科医务工作者在做好新型冠状病毒肺炎抗疫工作的同时,还要完成好眼科疾病的诊治工作。为了有助于大家更加高效安全地完成各项工作,本文特对新型冠状病毒肺炎疫情下眼科诊疗工作的风险及防护进行分析,并提出建议供参考。     

新型冠状病毒感染防控中眼科医务工作者的防护建议

在眼病诊疗过程中与患者近距离接触,存在着新型冠状病毒交叉感染的风险。本文简介新型冠状病毒感染的特点与鉴别,从眼科医护人员个人防护、眼科门诊防控管理、眼科病房防控管理以及眼科器械清洁消毒等方面提出建议及意见,希望对眼科医务工作者在新型冠状病毒感染防控中有所帮助。     

第二十六届全国眼外伤学术会议暨整合眼外科技术研讨会延期通知

尊敬的各位参会代表和参展企业:鉴于目前新型冠状病毒肺炎疫情防控需要,综合诸多方面的情况,经学会讨论,原定于2020年5月21日至23日在郑州市召开的第二十六届全国眼外伤学术会议暨整合眼外科技术研讨会(COTS2020)将推迟至2020年7月9日至11日举行。     

新型冠状病毒肺炎疫情期间眼外伤流行病学特点分析

目的：分析新型冠状病毒肺炎疫情期间眼外伤入院者疾病谱变化趋势及流行病学特点。

方法：回顾性病例分析。收集郑州大学第一附属医院眼科入院治疗的眼外伤者876例905眼,其中对照组(2019-01/06)545例565眼,研究组(2020-01/06)331例340眼。比较两组患者年龄、性别、受伤地点、受伤原因、居住地、受伤类型等信息。

结果：研究组眼外伤住院人数较对照组减少39.3%,对照组和研究组年龄均呈双峰样分布,分别为0～10岁(20.55%,21.45%)和41～50岁(17.98%,19.03%)占比最高,两组年龄分布无差异(P=0.907)。对照组和研究组均以男性为主,占比80.37%,83.69%(P=0.219)。研究组居家受伤比例(28.40%)高于对照组(11.38%)(P<0.001)。研究组机械性眼外伤占比(98.19%)高于对照组(95.60%)(P=0.041),开放性眼外伤占比(85.54%)高于对照组(76.58%)(P=0.001),无光感者占比(18.86%)高于对照组(9.53%)(P<0.001)。

结论：新型冠状病毒肺炎疫情期间,眼外伤住院患者显著减少,机械性眼外伤是主要眼外伤类型,在流行病暴发期间,仍应加强眼外伤的防护意识。     

眼科门诊医护人员对于新型冠状病毒肺炎的防护对策 △

目的 探讨在新型冠状病毒肺炎(COVID-19)疫情期间,眼科门诊医护人员的防控对策。方法 采用调查问卷的方法收集2020年1月1~24日、1月27日~2月2日、2月25日~3月25日眼科门诊就诊患者及医护人员的情况,包括患者的体温、流行病学史、疫区或外来人员接触史、目前症状(发热、咳嗽、乏力、眼红、分泌物等)以及近期接触人员的接触史等。同时制订COVID-19防控应急预案,进行医护人员眼部及全身防护,眼科器械清洁消毒制度。结果 COVID-19疫情初发期间(1月1~24日)我院眼科门诊接诊6 564例患者,每天共16名医护人员接诊患者;疫情高峰期间(1月27日~2月2日)共接诊262例患者,每天共8名医护人员参与接诊;疫情后期(2月25日~3月25日)共接诊4 503例患者,每天共16名医护人员参与接诊。通过进行医护人员眼部及全身防护、眼科器械清洁消毒等措施,截止目前眼科门诊未发现患者及医护人员感染病例。结论 COVID-19疫情期间,加大筛查力度,完善眼科门诊检查仪器设施消毒制度,保障了医护人员的安全。     

COVID-19 infection with keratitis as the first clinical manifestation

AIM: To report a case which keratitis is the first clinical manifestation of COVID-19 that occurred 3d earlier than the common COVID-19 symptoms. METHODS: Regular slit lamp examination, corneal scraping test, and chest computed tomography (CT) were performed for patients with COVID-19 infection. The ophthalmologic treatment included ganciclovir eye drop (50 mg/mL, 6 times/d). The treatment for diarrhea included Guifu Lizhong pills (TID). The antiviral therapy consisted of oseltamivir (75 mg capsule Q12H); therapy preventing bacterial infection consisted of azithromycin (250 mg tablet QD) and moxifloxacin (0.4 g tablet Q12H); and therapy for cough relief and fever prevention consisted of Chinese herbal decoction. RESULTS: A 35-year-old male suddenly suffered pain, photophobia, and tears in his right eye for one day without systemic COVID-19 symptoms. Patient was diagnosed with keratitis, which was seemingly different from common keratitis. Ganciclovir eye drop was initiated. The corneal scraping test for COVID-19 was positive. The chest CT images were abnormal confirming the diagnosis of COVID-19 infection. The antiviral and antibacterial therapies were initiated. Chinese herbal therapy was used for cough relief and fever prevention. After roughly two weeks, patient recovered from COVID-19. CONCLUSION: A new type of keratitis, atypical keratitis, is a clinical manifestation of COVID-19, and this clinical manifestation could appear 3d earlier than fever and cough. The earlier a COVID-19 clinical manifestation is identified, the earlier can a patient be directed to stay at home, and significantly fewer people would be infected.     

Impact of COVID-19 pandemic and national lockdown on ocular trauma at a tertiary eye care institute

Purpose:To evaluate the impact of the COVID-19 pandemic and the national lockdown on the demographic and clinical profile of patients presenting with ocular trauma.Methods:In this retrospective, hospital-based, comparative analysis, patients presenting to the emergency department with ocular trauma in the following COVID-19 period (March 25, 2020 to July 31, 2020) were compared with patients in the pre-COVID-19 period (March 25, 2019 to July 31, 2019).Results:Overall, 242 patients (COVID-19 period: 71 and pre-COVID-19 period: 171) presented with ocular trauma. The mean age of the patients in COVID-19 and pre-COVID-19 periods were 26.7 ± 17.3 and 34.1 ± 20.3 years, respectively (P = 0.008). A majority of patients (68.6%) in both groups were from the rural background. Home-related injuries were common in the COVID-19 period (78.8%) as compared to pre-COVID-19 period (36.4%) (P < 0.0001). Iron particles (29.5%) were the common inflicting agents in the COVID-19 period while it was plant leaves (25.5%) in the pre-COVID-19 period. The most common ocular diagnosis was open globe injury (40.8%) in the COVID-19 period and microbial keratitis (47.9%) in the pre-COVID-19 period. Surgical intervention was required in 46.4% of patients in the COVID-19 period and 32.1% of patients in the pre-COVID-19 period (P = 0.034).Conclusion:During the COVID-19 period, there was a significant decline in the number of patients presenting with ocular trauma. In this period, a majority of patients sustained ocular trauma in home-settings. About half the patients required surgical intervention which was most commonly rendered in the form of primary wound repair.     

Comparison of ocular trauma between normalized and the COVID-19 epidemic periods in China: a multi-center cross-sectional study

AIM: To compare the feature of ocular trauma between normalized period and the COVID-19 epidemic period in China, and to provide a profile for eye injuries in special times in future. METHODS: This is a multi-center cross-sectional study with 30 participated hospitals involving the China Ocular Trauma Society members. All hospitalized cases who visited the Ophthalmology Department in participated hospitals with eye injuries during the normalized period (2019) and the COVID-19 epidemic period (2020) were included in this study. Demographic characteristic of cases, date of injury, sites and types of injury were collected. RESULTS: This study involved 13 525 (61 cases with both eyes) injured cases. There were 7269 (53.74%) eye-injured cases and 6256 (46.26%) eye-injured cases in 2019 and 2020 separately. Compared with 2019, the incidence of ocular trauma in retirees, housewives and unemployed increased with year-on-year of 4.96%, 102.67%, and 11.64% among all occupations. In 2020, the incidence of eye injuries decreased in all injury sites except for an increase in home (30.29% year-on-year). The incidence of mechanical eye injuries decreased, while that of non-mechanical eye injuries (chemical/thermal/radiation) increased (47.45% year-on-year). There were 255 (3.51%, 255/7269) and 376 (6.01%, 376/6256) non-mechanical injured cases in 2019 and 2020 (Pearson Chi2=47.33, P<0.001) separately. CONCLUSION: During the COVID-19 epidemic period, the total cases of ocular trauma decrease but the proportion of non-mechanical ocular trauma increase. Penetrating is still the highest proportion among all types of mechanical ocular trauma. From a preventive point of view, protection for retired persons, housewives and unemployed persons should be improved during public health events period.     

新型冠状病毒肺炎的眼部表现

新型冠状病毒肺炎(coronavirus disease 2019,COVID-19,新冠肺炎)是由新型冠状病毒(novel coronavirus,SARS-CoV-2,新冠病毒)引起的一种具有高度传染性的疾病,目前在世界各地广泛流行,并引起全球性恐慌。研究表明,新冠病毒可以通过眼部黏膜传播,因此眼科医务人员更容易受到感染。新冠肺炎患者眼部表现主要累及结膜、角膜、巩膜、前房、瞳孔、视网膜、视神经和视皮层、眼外肌及其颅神经支配、眼眶和泪器系统等。病毒性结膜炎是新冠肺炎患者最常见的眼部表现。新冠肺炎流行期间,为了眼科医务人员免受感染,安全地开展临床工作,本文依据近年来相关文献报道总结了新冠肺炎的眼部表现,主要包括流行病学、病理生理、临床表现等方面。     

四川乐山市人民医院738例住院眼外伤分析

目的 分析5年间住院眼外伤患者的相关因素。方法 回顾性统计5年间住院眼外伤患者资料。分别逐年比较分析眼外伤所占比例、性别、年龄、眼别、外伤后就诊时间、外伤类型、致伤物、并发症、治疗前后视力等情况。结果 5年来住院眼外伤738例（764只眼）占眼科住院总人数的6．45％,眼外伤所占比例逐年降低。男女之比为4．31：1,左右眼比例相近,受伤年龄段主要为41～60岁,其次为19～40岁。外伤后就诊时间在1d以内者占62．74％。主要致伤物为钝器,其次为锐器及爆炸物。主要外伤类型：眼挫伤占38．64％,角巩膜穿孔伤占17．17％,角膜穿孔伤占11．87％。以前房积血、晶状体脱位、继发性青光眼、外伤性白内障和玻璃体积血为主要并发症。治疗前盲目占68．97％,治疗后盲目占45．15％。眼球摘除61眼,占7．98％。结论 建议加强眼外伤预防知识宣传,做好预防工作,及时有效救治,提高眼外伤一期和二期诊治水平,以降低致盲率。