Advantages and challenges of oestrogen-free hormonal contraception

Abstract

Background:

Not all women tolerate hormonal contraceptives containing oestrogens.     

Utilization of duloxetine and celecoxib in osteoarthritis patients

Abstract

Objectives:

To describe utilization patterns of duloxetine and celecoxib and subsequent opioid use among patients with osteoarthritis.     

Long-term safety and efficacy of aliskiren and valsartan combination with or without the addition of HCT in patients with hypertension

Abstract

Objective:

To assess the long-term safety and antihypertensive efficacy of aliskiren/valsartan 300/320?mg combination.     

Association between hypoglycemia and inpatient mortality and length of hospital stay in hospitalized,insulin-treated patients

Abstract

Objective:

To assess the impact of hypoglycemia on clinical outcomes among hospitalized, insulin-treated patients.     

Acute back pain: benefits and risks of current treatments

Abstract

Objective:

To review the efficacy and safety of current treatments for acute low back pain.     

Comparative efficacy and acceptability of pharmacotherapeutic agents for anxiety disorders in children and adolescents: a mixed treatment comparison meta-analysis

Abstract

Objective:

to compare efficacy and acceptability of different pharmacotherapeutic agents for treating anxiety disorders in children and adolescents     

Patient and physician perceptions of treatment of moderate-to-severe chronic pain with oral opioids

Abstract

Objective:

To study physician and patient perceptions of moderate-to-severe chronic pain and its management with oral opioids.     

Assessing achievement and maintenance of glycemic control by patients initiating basal insulin

Abstract

Objective:

Describe characteristics of diabetic patients who initiated basal insulin and assess their glycemic control.     

Incidence and risk of denosumab-related hypocalcemia in cancer patients: a systematic review and pooled analysis of randomized controlled studies

Abstract

Purpose:

The aim of this study is to evaluate the frequency and relative risk of hypocalcemia in cancer patients receiving denosumab.     

Impact of asthma controller medications on medical and economic resource utilization in adult asthma patients

Abstract

Objective:

To compare asthma-related resource utilization, adherence and costs among adults prescribed asthma controller regimens.     

A pooled analysis of exenatide use and risk of acute pancreatitis

Abstract

Objective:

To estimate the association between exenatide BID use and acute pancreatitis across two claims-based studies.     

Management of neuropathic pain after surgical and non-surgical trauma with lidocaine 5% patches: study of 40 consecutive cases

Abstract

Objective:

To determine the efficacy of lidocaine 5% patches in patients with PNCCP.     

Efficacy and safety of celecoxib versus diclofenac and omeprazole in elderly arthritis patients: a subgroup analysis of the CONDOR trial

Abstract

Objective:

To compare the safety and efficacy of celecoxib versus diclofenac slow release (SR) plus omeprazole in elderly arthritis patients.     

Relationship between background cancer pain,breakthrough pain,and analgesic treatment: a preliminary study for a better interpretation of epidemiological and clinical studies

Abstract

Background:

The different operational definitions of breakthrough cancer pain (BTcP) has generated unclear epidemiological data.     

Long-term safety,tolerability, and efficacy of fesoterodine treatment in men and women with overactive bladder symptoms

Abstract

Objective:

To evaluate long-term safety, tolerability, and efficacy of fesoterodine for men and women with overactive bladder (OAB) symptoms.     

Short- and long-term efficacy and safety of duloxetine in women with predominant stress urinary incontinence

Abstract

Objective:

To evaluate short- and long-term safety and efficacy of duloxetine in women with predominant stress urinary incontinence (SUI).     

Efficacy,safety, and pharmacokinetics of ambrisentan in Japanese adults with pulmonary arterial hypertension

Abstract

Objective:

To investigate the efficacy, safety, and pharmacokinetics of ambrisentan in Japanese adults with pulmonary arterial hypertension (PAH).     

Economic burden and quality of life of vulvodynia in the United States

Abstract

Objective:

To explore the economic burden and quality of life of vulvodynia in the United States.     

Colesevelam in the treatment of hypercholesterolemia and hyperglycemia: a retrospective analysis from an ambulatory care medical network

Abstract

Objective:

To examine outcomes associated with colesevelam treatment among patients with hypercholesterolemia in real-world clinical practice.     

Reasons for discontinuation and continuation of antipsychotics in the treatment of schizophrenia from patient and clinician perspectives

Abstract

Objective:

To identify reasons for discontinuation and continuation of antipsychotic medications in the treatment of schizophrenia from the patients’ and their clinicians’ perspectives.