Correlates of alcohol use in adults with ADHD and comorbid alcohol use disorders: exploratory analysis of a placebo-controlled trial of atomoxetine

Abstract

Background:

Attention-deficit/hyperactivity disorder (ADHD) and substance use disorder are often comorbid in adults. The effects of ADHD treatment on comorbid alcohol use disorder have not been extensively studied.     

Treatment stabilization in children and adolescents with attention-deficit/hyperactivity disorder: data from the Netherlands

Abstract

Objective:

To evaluate the number of patients reaching stable treatment with a stimulant (methylphenidate or dexamphetamine) or non-stimulant (atomoxetine) attention-deficit/hyperactivity disorder (ADHD) medication approved for use in the Netherlands, and the time to treatment stabilization among children and adolescents aged 6–17 years.     

Attention deficit hyperactivity disorder in the European adult population: prevalence,disease awareness,and treatment guidelines

Abstract

Background:

Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological disorder with childhood onset and persistence into adolescence and adulthood.     

Long-term treatment outcomes with lisdexamfetamine dimesylate for adults with attention-deficit/hyperactivity disorder stratified by baseline severity

Abstract

Objective:

To examine the impact of baseline severity on lisdexamfetamine dimesylate (LDX) efficacy in a long-term study of adults with attention-deficit/hyperactivity disorder (ADHD).     

Effects of atomoxetine on self-reported high-risk behaviors and health-related quality of life in adolescents with ADHD

Abstract

Objective:

This study measured the effects of atomoxetine HCl on high-risk behaviors and health-related quality of life in adolescents with attention-deficit/hyperactivity disorder (ADHD), using a subgroup analysis of data from a previous clinical trial.     

HRQL and medication satisfaction in children with ADHD treated with the methylphenidate transdermal system

Abstract

Objective:

To evaluate the impact of methylphenidate transdermal system (MTS) on health-related quality of life (HRQL) and medication satisfaction in children with attention-deficit/hyperactivity disorder (ADHD) as well as to identify potential moderators of HRQL and medication satisfaction.     

Retrospective analysis of variation in heavy menstrual bleeding treatments by age and underlying cause

Abstract

Objective:

To describe treatment patterns associated with heavy menstrual bleeding (HMB) in US practice.     

Taxane-based mono- or combination therapy for managing metastatic breast cancer (MBC) in routine practice: a multinational prospective observational study

Abstract

Objectives:

Taxanes are standard for first-line chemotherapy of metastatic breast cancer (MBC), but indications for single-agent versus combination treatment remain controversial. This non-interventional study in 12 different countries explored treatment patterns and progression-free survival (PFS) in routine practice.     

Evaluation of treatment continuation with alosetron by IBS-D severity criteria

Abstract

Objectives:

This article evaluates the characteristics and treatment patterns of female patients with severe diarrhea-predominant irritable bowel syndrome (IBS-D) who were treated with alosetron under a risk management program.     

Patterns of treatment with chemotherapy and monoclonal antibodies for metastatic colorectal cancer in Western Europe

Abstract

Background and objectives:

Treatment outcomes improved in metastatic colorectal cancer (mCRC) due to the introduction of new chemotherapies and monoclonal antibodies. This study describes current patterns of pharmacological treatment for mCRC in clinical practice in four European countries.     

Relationship between physician specialty and allopurinol prescribing patterns: a study of patients with gout in managed care settings

Abstract

Objective:

Allopurinol is used to lower serum uric acid (sUA) levels in gout patients. The objective of this study was to investigate the influence of physician specialty on allopurinol treatment patterns and sUA control.     

Glycemic control and the first use of oral antidiabetic agents among patients with type 2 diabetes mellitus

Abstract

Objective:

Examine how patients diagnosed with type 2 diabetes mellitus (T2DM) are treated with oral antidiabetic (OAD) agents and the relationship between treatment patterns and glycemic control.     

Variation in the use of biologics in the management of rheumatoid arthritis across the UK

Abstract

Objectives:

Treatment options for rheumatoid arthritis (RA) include conventional synthetic disease-modifying antirheumatic drugs (sDMARDs) and newer biologic DMARDs (biologics). This study describes treatment patterns, adherence to guidance and outcomes at hospital/regional level in the UK.     

First-year treatment costs among new initiators of topical prostaglandin analog identified from November 2007 through April 2008

Abstract

Objective:

Ocular surface disease (OSD) is a common side effect of ophthalmic medications containing the preservative benzalkonium chloride (BAK). Little is known whether and how glaucoma treatment patterns and annual costs vary based on the presence of BAK. The objective of this analysis was to estimate first-year treatment costs among new initiators of topical prostaglandin analogs in a managed care population.     

Characterizing and understanding body weight patterns in patients treated with pregabalin

Abstract

Objective:

We examined patterns of weight change among patients treated with pregabalin for up to 1 year.     

Dosing patterns of three tumor necrosis factor blockers among patients with rheumatoid arthritis in a large United States managed care population

Abstract

Objective:

To describe dosing patterns of etanercept, adalimumab, and infliximab in rheumatoid arthritis (RA) patients in US managed care.     

Medication dosing patterns associated with duloxetine and pregabalin among patients with fibromyalgia

Abstract

Objective:

To examine medication dosing patterns of duloxetine and pregabalin among patients with fibromyalgia.     

Utilization of duloxetine and celecoxib in osteoarthritis patients

Abstract

Objectives:

To describe utilization patterns of duloxetine and celecoxib and subsequent opioid use among patients with osteoarthritis.     

Real-world use patterns of olanzapine long-acting injection in the United States: comparison to the recommended dosing strategy

Abstract

Objective:

Recommended doses for olanzapine long-acting injection (olanzapine LAI) are 150?mg/2 weeks, 210?mg/2 weeks, 300?mg/2 or 4 weeks, and 405?mg/4 weeks. This analysis evaluated the dosing and interval patterns to compare the actual dosing patterns with the recommended dosing strategy.     

Subcutaneous specific immunotherapy for seasonal allergic rhinitis: a review of treatment practices in the US and Europe

Abstract

Background:

Subcutaneous specific immunotherapy (SCIT) is claimed to be successful both in the US and Europe, yet treatment methodology differs.