Assessing achievement and maintenance of glycemic control by patients initiating basal insulin

Abstract

Objective:

Describe characteristics of diabetic patients who initiated basal insulin and assess their glycemic control.     

An observational study to validate the Satisfaction Measure of the Injection of Growth Hormone Therapy (SMIGHTy) questionnaire

Abstract

Objective:

The objective of this study was to psychometrically evaluate a tool to measure adult caregivers’ level of satisfaction with the delivery device used to administer injections of recombinant human growth hormone (rhGH) to a child – the Satisfaction Measure of the Injection of Growth Hormone Therapy (SMIGHTy ) questionnaire.     

Evaluation of treatment continuation with alosetron by IBS-D severity criteria

Abstract

Objectives:

This article evaluates the characteristics and treatment patterns of female patients with severe diarrhea-predominant irritable bowel syndrome (IBS-D) who were treated with alosetron under a risk management program.     

Generic substitution: additional challenge for adherence in hypertensive patients?

Abstract

Objective:

This study aims to investigate whether, and in what way, generic substitution affects drug adherence in hypertensive patients.     

An evaluation of patient and physician satisfaction with controlled-release oxybutynin 15 mg as a one-step daily dose in elderly and non-elderly patients with overactive bladder: results of the STOP study

Abstract

Objective:

Evaluate patient and physician satisfaction with a novel formulation of a once-daily controlled-release (CR) oxybutynin (Uromax ) 15-mg tablet as both the initial and maintenance dose in elderly and non-elderly patients with overactive bladder (OAB).     

Development of the Asthma Treatment Satisfaction Measure

Abstract

Objective:

Study aims were to develop and assess the measurement properties of a four-part treatment satisfaction measure for patients with asthma. The Asthma Treatment Satisfaction Measure (ATSM) incorporates specific attributes representing patient expectations, treatment preferences, self-reported treatment outcomes, and overall treatment satisfaction. This paper describes patients’ ability to detect change in their satisfaction with asthma therapies using the ATSM.     

A systematic review of adherence,treatment satisfaction and costs,in fixed-dose combination regimens in type 2 diabetes

Abstract

Objective:

Oral antidiabetics have comparable safety and efficacy when used as fixed-dose combination therapies (FDCT) or loose-pill combination therapies (LPCT) for patients with T2DM. To evaluate alternative outcomes to safety and efficacy with FDCT, a systematic review of literature was conducted.     

Accuracy and preference assessment of prefilled insulin pen versus vial and syringe with diabetes patients,caregivers, and healthcare professionals

Abstract

Objectives:

The primary objective of this study was to investigate the dosing accuracy of the new prefilled FlexTouch insulin pen (FT) in comparison to conventional vial and syringe (V&S) when used by patients (Pts), caregivers (CG) and healthcare professionals (HCPs).     

Assessment of new application system in Portuguese patients with relapsing-remitting multiple sclerosis

Abstract

Objective:

To evaluate the satisfaction level of multiple sclerosis (MS) patients treated with interferon beta-1b (IFNβ-1b, Betaferon*) using a newly developed application system compared to their currently used application system.     

Worry vs. knowledge about treatment-associated hypoglycaemia and weight gain in type 2 diabetic patients on metformin and/or sulphonylurea

Abstract

Background and aims:

Hypoglycaemia and body weight gain are side effects of certain glucose-lowering drugs, e.g. sulphonylurea (SU) compounds. Type 2 diabetes mellitus (T2DM) is often treated with multiple oral antidiabetic drugs complicating patient insight into drug safety and side effects. We aimed to elucidate the extent of patient worry about hypoglycaemia and body weight gain contra their knowledge about these two phenomena being actual side effects of SU.     

Patient perceptions associated with the 5% lidocaine medicated plaster in daily practice

Abstract

Objective:

To evaluate patients’ perceptions of 5% lidocaine medicated plaster for treatment of chronic neuropathic pain in daily clinical practice.     

Willingness to pay for health improvements associated with anti-diabetes treatments for people with type 2 diabetes

Abstract

Objectives:

This study aimed to investigate the most important consequences of diabetes medication, as measured by the patients’ willingness to pay (WTP).     

Menorrhagia Impact Questionnaire: assessing the influence of heavy menstrual bleeding on quality of life

Abstract

Objective:

Menorrhagia, or heavy menstrual bleeding (HMB), has a negative impact on women’s quality of life (QOL). The objective was to develop, validate, and assess the performance of a disease-specific patient-reported outcome (PRO) measurement instrument for HMB (the Menorrhagia Impact Questionnaire [MIQ]).     

Management of patients with transient ischemic attack: insight from real-life clinical practice in Europe and the United States

Abstract

Objective:

Transient ischemic attack (TIA) is a serious condition which should be considered on the same spectrum as other conditions involving brain ischemia. Efficient management of these patients is therefore critical. The aim of this research was to gain insights into ‘real-world’ global trends of the current management approaches for patients with suspected and diagnosed TIA, and highlight the unmet need and areas of improvement to ensure effective management of this patient group.     

Tadalafil therapy and health-related quality of life in pulmonary arterial hypertension

Abstract

Background:

Pulmonary arterial hypertension (PAH) is a rare, progressive lung disorder that impairs performance of daily activities and quality of life (QoL), leading to right heart failure and death. Treatment options include prostanoids, endothelin antagonists, and phosphodiesterase type 5 inhibitors (e.g., tadalafil). Currently there is no cure for PAH, but tadalafil has improved exercise capacity in these patients.     

Clinical assessment of the accuracy of blood glucose measurement devices

Abstract

Objectives:

Blood glucose meters for patient self-measurement need to comply with the accuracy standards of the ISO 15197 guideline. We investigated the accuracy of the two new blood glucose meters BG*Star and iBG*Star (Sanofi-Aventis) in comparison to four other competitive devices (Accu-Chek Aviva, Roche Diagnostics; FreeStyle Freedom Lite, Abbott Medisense; Contour, Bayer; OneTouch Ultra 2, Lifescan) at different blood glucose ranges in a clinical setting with healthy subjects and patients with type 1 and type 2 diabetes. BGStar and iBGStar are employ dynamic electrochemistry, which is supposed to result in highly accurate results.     

Management of neuropathic pain after surgical and non-surgical trauma with lidocaine 5% patches: study of 40 consecutive cases

Abstract

Objective:

To determine the efficacy of lidocaine 5% patches in patients with PNCCP.     

Evaluation of eye drop administration technique in patients with glaucoma or ocular hypertension

Abstract

Objective:

To evaluate eye drop administration by patients at multiple visits in the setting of a randomized controlled trial.     

Aripiprazole in patients with bipolar mania and beyond: an update of practical guidance

Abstract

Background:

Aripiprazole is an atypical antipsychotic with a pharmacological and clinical profile distinct from other atypical antipsychotics.     

Proof of concept study: does fenofibrate have a role in sleep apnoea syndrome?

Abstract

Objective:

To investigate the effect of fenofibrate on sleep apnoea indices.