Long-term clinical and economic outcomes associated with angiotensin II receptor blocker use in hypertensive patients

Abstract

Objective:

To examine clinical and economic outcomes associated with angiotensin II receptor blockers (ARB).     

Management of neuropathic pain after surgical and non-surgical trauma with lidocaine 5% patches: study of 40 consecutive cases

Abstract

Objective:

To determine the efficacy of lidocaine 5% patches in patients with PNCCP.     

Utilization of duloxetine and celecoxib in osteoarthritis patients

Abstract

Objectives:

To describe utilization patterns of duloxetine and celecoxib and subsequent opioid use among patients with osteoarthritis.     

Factors associated with warfarin discontinuation,including bleeding patterns,in atrial fibrillation patients

Abstract

Objective:

To determine risk factors for both warfarin discontinuation and bleeding in patients with atrial fibrillation (AF).     

Patient and physician perceptions of treatment of moderate-to-severe chronic pain with oral opioids

Abstract

Objective:

To study physician and patient perceptions of moderate-to-severe chronic pain and its management with oral opioids.     

Characterizing and understanding body weight patterns in patients treated with pregabalin

Abstract

Objective:

We examined patterns of weight change among patients treated with pregabalin for up to 1 year.     

Hypoglycemia in patients with type 2 diabetes from India and Malaysia treated with sitagliptin or a sulfonylurea during Ramadan: a randomized,pragmatic study

Abstract

Objective:

To compare the incidence of symptomatic hypoglycemia between sitagliptin and sulfonylurea in Muslim patients with type 2 diabetes who fasted during Ramadan.     

Safety,tolerability, pharmacokinetics and pharmacodynamics of albiglutide,a long-acting GLP-1-receptor agonist,in Japanese subjects with type 2 diabetes mellitus

Abstract

Objective:

To investigate safety, pharmacokinetics and pharmacodynamics of albiglutide in Japanese subjects with type 2 diabetes mellitus.     

Medication dosing patterns associated with duloxetine and pregabalin among patients with fibromyalgia

Abstract

Objective:

To examine medication dosing patterns of duloxetine and pregabalin among patients with fibromyalgia.     

A 25-week,open-label trial investigating rivastigmine transdermal patches with concomitant memantine in mild-to-moderate Alzheimer’s disease: a post hoc analysis

Abstract

Objective:

To investigate the tolerability and efficacy of the rivastigmine transdermal patch in patients with mild-to-moderate Alzheimer’s disease receiving concomitant memantine.     

Effect of fesoterodine 4 mg on bladder diary and patient-reported outcomes during the first week of treatment in subjects with overactive bladder

Abstract

Objective:

To assess the onset of efficacy of fesoterodine 4?mg versus placebo in subjects with overactive bladder (OAB) symptoms     

Urinary flow and urinary symptoms in elderly males exposed to either escitalopram or duloxetine

Abstract

Objective:

To profile the effects of escitalopram with duloxetine on urinary flow rate and symptoms in elderly males aged 55–75 years.     

Economic burden of psoriasis compared to the general population and stratified by disease severity

Abstract

Objective:

To evaluate health care utilization and costs for patients with psoriasis vs. the general population and by psoriasis severity.     

Efficacy,safety, and pharmacokinetics of ambrisentan in Japanese adults with pulmonary arterial hypertension

Abstract

Objective:

To investigate the efficacy, safety, and pharmacokinetics of ambrisentan in Japanese adults with pulmonary arterial hypertension (PAH).     

Retrospective analysis of variation in heavy menstrual bleeding treatments by age and underlying cause

Abstract

Objective:

To describe treatment patterns associated with heavy menstrual bleeding (HMB) in US practice.     

Aripiprazole in patients with bipolar mania and beyond: an update of practical guidance

Abstract

Background:

Aripiprazole is an atypical antipsychotic with a pharmacological and clinical profile distinct from other atypical antipsychotics.     

Safety and efficacy of maintenance infliximab therapy for moderate-to-severe Crohn’s disease in children: REACH open-label extension

Abstract

Objective:

Assess long-term effects of maintenance infliximab therapy in children with moderately-to-severely active Crohn’s disease.     

Assessment of safety,tolerability and effectiveness of adjunctive aripiprazole to lithium/valproate in bipolar mania: a 46-week,open-label extension following a 6-week double-blind study

Abstract

Objective:

This study evaluated the long-term tolerability and effectiveness of aripiprazole adjunctive to lithium or valproate in partial responders with bipolar mania.     

Proof of concept study: does fenofibrate have a role in sleep apnoea syndrome?

Abstract

Objective:

To investigate the effect of fenofibrate on sleep apnoea indices.     

Advantages and challenges of oestrogen-free hormonal contraception

Abstract

Background:

Not all women tolerate hormonal contraceptives containing oestrogens.