Long-term safety and efficacy of aliskiren and valsartan combination with or without the addition of HCT in patients with hypertension

Abstract

Objective:

To assess the long-term safety and antihypertensive efficacy of aliskiren/valsartan 300/320?mg combination.     

Economic burden and quality of life of vulvodynia in the United States

Abstract

Objective:

To explore the economic burden and quality of life of vulvodynia in the United States.     

The use of the Asthma Control Test in general practice and its correlation with asthma control according to the GINA guidelines

Abstract

Background:

The GINA guidelines have redefined the primary goal of asthma treatment as achieving optimum control.     

Long-term treatment of osteoporosis in postmenopausal women: a review from the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) and the International Osteoporosis Foundation (IOF)

Abstract

Introduction:

Postmenopausal osteoporosis is a chronic disease requiring treatment that balances long-term fracture efficacy against risk.     

Efficacy and safety of celecoxib versus diclofenac and omeprazole in elderly arthritis patients: a subgroup analysis of the CONDOR trial

Abstract

Objective:

To compare the safety and efficacy of celecoxib versus diclofenac slow release (SR) plus omeprazole in elderly arthritis patients.     

Reasons for discontinuation and continuation of antipsychotics in the treatment of schizophrenia from patient and clinician perspectives

Abstract

Objective:

To identify reasons for discontinuation and continuation of antipsychotic medications in the treatment of schizophrenia from the patients’ and their clinicians’ perspectives.     

Economic burden of psoriasis compared to the general population and stratified by disease severity

Abstract

Objective:

To evaluate health care utilization and costs for patients with psoriasis vs. the general population and by psoriasis severity.     

Colesevelam in the treatment of hypercholesterolemia and hyperglycemia: a retrospective analysis from an ambulatory care medical network

Abstract

Objective:

To examine outcomes associated with colesevelam treatment among patients with hypercholesterolemia in real-world clinical practice.     

Complexities in the pharmacologic management of osteoarthritis pain

Abstract

Objective:

To discuss challenges in the pharmacologic management of osteoarthritis (OA) pain.     

Consensus guidelines for the use of bowel preparation prior to colonic diagnostic procedures: colonoscopy and small bowel video capsule endoscopy

Abstract

Background:

Adequate bowel preparation prior to colonic diagnostic procedures is essential to ensure adequate visualisation.     

Advantages and challenges of oestrogen-free hormonal contraception

Abstract

Background:

Not all women tolerate hormonal contraceptives containing oestrogens.     

Effect of ticagrelor on the pharmacokinetics of ethinyl oestradiol and levonorgestrel in healthy volunteers

Abstract

Background:

Cytochrome P450 3 A is involved in ticagrelor and ethinyl oestradiol/levonorgestrel metabolism; so a potential drug–drug interaction may occur.     

Subcutaneous specific immunotherapy for seasonal allergic rhinitis: a review of treatment practices in the US and Europe

Abstract

Background:

Subcutaneous specific immunotherapy (SCIT) is claimed to be successful both in the US and Europe, yet treatment methodology differs.     

Lacosamide as adjunctive therapy for partial-onset epileptic seizures: a review of the clinical and economic literature

Abstract

Objective:

This article provides a short but comprehensive pharmacotherapeutic update of adjunctive therapy with lacosamide for partial-onset seizures in adult patients.     

Comparison of the dipeptidyl peptidase-4 inhibitor vildagliptin and the sulphonylurea gliclazide in combination with metformin,in Muslim patients with type 2 diabetes mellitus fasting during Ramadan: results of the VECTOR study

Abstract

Objective:

To compare the incidence of hypoglycaemic events (HEs) in a real-world setting in Muslim patients with type 2 diabetes mellitus fasting during Ramadan.     

Presentation of atrial fibrillation and its management by cardiologists in the ambulatory and hospital setting: MOVE cross-sectional study

Abstract

Objective:

The aim of the study was to collect comprehensive data on atrial fibrillation (AF) in ambulatory and hospital-based management in Germany.     

The effect of udenafil on the hemodynamics of healthy male volunteers administered tamsulosin

Abstract

Objective:

The purpose of this study is to evaluate the hemodynamic interactions between udenafil and tamsulosin.     

Association between hypoglycemia and inpatient mortality and length of hospital stay in hospitalized,insulin-treated patients

Abstract

Objective:

To assess the impact of hypoglycemia on clinical outcomes among hospitalized, insulin-treated patients.     

Acute back pain: benefits and risks of current treatments

Abstract

Objective:

To review the efficacy and safety of current treatments for acute low back pain.     

Non-clinical pharmacology,pharmacokinetics, and safety findings for the antihistamine bepotastine besilate

Abstract

Scope:

The purpose of this review is to examine published non-clinical literature on the antihistamine bepotastine besilate, including pharmacokinetic and pharmacologic properties.