Long-term treatment outcomes with lisdexamfetamine dimesylate for adults with attention-deficit/hyperactivity disorder stratified by baseline severity

Abstract

Objective:

To examine the impact of baseline severity on lisdexamfetamine dimesylate (LDX) efficacy in a long-term study of adults with attention-deficit/hyperactivity disorder (ADHD).     

HRQL and medication satisfaction in children with ADHD treated with the methylphenidate transdermal system

Abstract

Objective:

To evaluate the impact of methylphenidate transdermal system (MTS) on health-related quality of life (HRQL) and medication satisfaction in children with attention-deficit/hyperactivity disorder (ADHD) as well as to identify potential moderators of HRQL and medication satisfaction.     

Effects of atomoxetine on self-reported high-risk behaviors and health-related quality of life in adolescents with ADHD

Abstract

Objective:

This study measured the effects of atomoxetine HCl on high-risk behaviors and health-related quality of life in adolescents with attention-deficit/hyperactivity disorder (ADHD), using a subgroup analysis of data from a previous clinical trial.     

Differences in rates of hypoglycemia and health care costs in patients treated with insulin aspart in pens versus vials

Abstract

Objectives:

To study whether initiation of insulin aspart therapy with a pen vs. a vial/syringe has an impact on the risk of subsequent hypoglycemic episodes and health care costs.     

Correlates of alcohol use in adults with ADHD and comorbid alcohol use disorders: exploratory analysis of a placebo-controlled trial of atomoxetine

Abstract

Background:

Attention-deficit/hyperactivity disorder (ADHD) and substance use disorder are often comorbid in adults. The effects of ADHD treatment on comorbid alcohol use disorder have not been extensively studied.     

Intranasal ketorolac for acute postoperative pain

Abstract

Background:

Efficacy and tolerability of intranasal ketorolac (SPRIX®) was assessed in abdominal surgery patients.     

Efficacy and safety of biphasic insulin aspart 70/30 in type 2 diabetes patients of different race or ethnicity (INITIATEplus trial)

Abstract

Objective:

To determine if self-titration using biphasic insulin aspart 70/30 (BIAsp 30) had a different impact on efficacy and safety across different racial/ethnic subgroups.     

Superiority of fluticasone propionate/formoterol fumarate versus fluticasone propionate alone in patients with moderate-to-severe asthma: a randomised controlled trial

Abstract

Objective:

To demonstrate the efficacy and safety of fluticasone propionate/formoterol fumarate (flutiform) in a pressurised metered-dose inhaler (pMDI) compared to two formulations of the fluticasone propionate component (Skyepharma fluticasone [SKP FP] or Flovent, GlaxoSmithKline [GSK FP]) in adults and adolescents with moderate-to-severe asthma.     

Medication dosing patterns associated with duloxetine and pregabalin among patients with fibromyalgia

Abstract

Objective:

To examine medication dosing patterns of duloxetine and pregabalin among patients with fibromyalgia.     

Long-term safety and efficacy of aliskiren and valsartan combination with or without the addition of HCT in patients with hypertension

Abstract

Objective:

To assess the long-term safety and antihypertensive efficacy of aliskiren/valsartan 300/320?mg combination.     

Attention deficit hyperactivity disorder in the European adult population: prevalence,disease awareness,and treatment guidelines

Abstract

Background:

Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological disorder with childhood onset and persistence into adolescence and adulthood.     

Prevention of episodic migraine with topiramate: a prospective 24-week,open-label,flexible-dose clinical trial with optional 24 weeks follow-up in a community setting

Abstract

Objective:

To explore efficacy and safety outcomes of topiramate for episodic migraine prevention in community practice.     

Work productivity loss in patients with dry eye disease: an online survey

Abstract

Objective:

To assess the impact of dry eye disease (DED) on productivity.     

Hypoglycemia in patients with type 2 diabetes from India and Malaysia treated with sitagliptin or a sulfonylurea during Ramadan: a randomized,pragmatic study

Abstract

Objective:

To compare the incidence of symptomatic hypoglycemia between sitagliptin and sulfonylurea in Muslim patients with type 2 diabetes who fasted during Ramadan.     

Characterizing and understanding body weight patterns in patients treated with pregabalin

Abstract

Objective:

We examined patterns of weight change among patients treated with pregabalin for up to 1 year.     

Smoking influences response to inhaled corticosteroids in patients with asthma: a meta-analysis

Abstract

Objective:

To determine the effects of smoking on efficacy of inhaled corticosteroids in asthmatics.     

The prevalence of chronic pain with an analysis of countries with a Human Development Index less than 0.9: a systematic review without meta-analysis

Abstract

Background:

To date, there are no systematic reviews of epidemiological studies of chronic pain in the developing world.     

Willingness to pay for health improvements associated with anti-diabetes treatments for people with type 2 diabetes

Abstract

Objectives:

This study aimed to investigate the most important consequences of diabetes medication, as measured by the patients’ willingness to pay (WTP).     

Long-term clinical and economic outcomes associated with angiotensin II receptor blocker use in hypertensive patients

Abstract

Objective:

To examine clinical and economic outcomes associated with angiotensin II receptor blockers (ARB).     

Factors associated with warfarin discontinuation,including bleeding patterns,in atrial fibrillation patients

Abstract

Objective:

To determine risk factors for both warfarin discontinuation and bleeding in patients with atrial fibrillation (AF).