湿润烧伤膏预防乳腺癌术后皮瓣坏死122例临床分析

目的：评估湿润烧伤膏预防乳腺癌术后切口皮瓣坏死等并发症的疗效。方法：在122例乳腺癌病人中有64例病人术后立即在切口边缘应用涂有湿润烧伤膏（MEBO）的无菌纱布外敷,加压包扎;另有58例病人术后仅常规加压包扎治疗,对比观察住院期间手术切缘皮瓣缺血坏死及感染表现。结果：64例乳腺癌病人术后切口2例皮瓣坏死;常规处理病人有10例出现不同程度的皮瓣坏死。结论：在乳腺癌术后切口边缘应用MEBO,可有效预防术后皮瓣坏死等并发症。     

Hyperbaric oxygen treatment for carbon monoxide poisoning in pregnancy: a case report.

Carbon monoxide (CO) poisoning is one of the most common forms of poisoning in the United States. When CO poisoning occurs in the pregnant patient, it is extremely toxic to the mother and fetus in terms of central nervous system disorders and delayed central nervous system sequelae. Controversy exists in treating the pregnant patient with hyperbaric oxygen (HBO) because of the unknown effects of high partial pressures of oxygen on the fetus. HBO therapy is beneficial in CO poisoning because of its effect of first increasing oxygen concentration and causing a shift in the oxygen dissociation curve from the left to the right. Second, by causing a diminished CO interaction with cytochrome oxidase, HBO allows mitochondria to use oxygen more effectively. Third, HBO may reduce lipid peroxidation which may be responsible for neurological deterioration and delayed central nervous system sequelae. Fourth, decreased CO influence through HBO may reduce changes in the myocardium as a result of CO poisoning, if cardiovascular disease is already present. A case study of successful HBO therapy used during pregnancy is presented and effects of CO on the fetus are discussed.     

湿润烧伤膏治疗乳腺癌术后皮瓣坏死的临床体会

目的：探讨湿润烧伤膏治疗乳腺癌术后皮瓣坏死的临床疗效。方法：乳腺癌术后皮瓣坏死范围确定后，剪去坏死皮瓣，创面应用湿润暴露疗法。结果：23例患经湿润烧伤膏治疗后全部治愈，疗程最短2周，最长6周。结论：湿润烧伤膏具有抗感染、改善微循环、清除坏死组织、促进创面愈合等作用。     

高压氧综合治疗海绵窦综合征一例

海绵窦综合征是由各种蝶鞍旁损害累及海绵窦所致,肿瘤、颈动脉瘤、颈动脉-海绵窦瘘和炎症是海绵窦综合征的主要病因.2007年9月我中心收治1例由外院误诊并给予手术治疗的海绵窦综合征患者.现报告如下.     

Hyperbaric oxygen for a thalassaemic leg ulcer

A thalassaemic ulcer in a male Greek Cypriot patient, resistant to standard medical treatment, was treated using hyperbaric oxygen in a recompression chamber. The patient breathed 100% oxygen by face mask whilst the chamber was compressed with air to a pressure of 2.5 atmospheres absolute. The ulcer became fully epithelialised within three weeks of starting treatment.     

湿润烧伤膏治疗大面积过敏性皮肤坏死一例

患儿，女，6个月，因臀部、双下肢过敏性皮肤、软组织坏死20天，于2003年3月10日入院。患儿曾于2003年2月18日因发热在当地诊所就诊，给予口服“安乃近片”等药物后，臀部及双下肢出现紫瘢，诊断为“皮肤药物过敏”，给予静脉补液、抗过敏等措施治疗，10天后臀部、双下肢     

Hyperbaric treatment of arterial CO2 embolism occuring after laparoscopic surgery: a case report.

Arterial carbon dioxide (CO2) embolism is a serious and sometimes fatal iatrogenic medical condition encountered in surgery. A thirty-five year old Caucasian female developed a CO2 embolism during a laparoscopic appendectomy. After initial resuscitation and completion of the surgery, she was treated with hyperbaric oxygen (HBO2) to help reduce the size of large CO2 bubbles that had migrated into her left ventricle during surgery. The HBO2 protocol was 2.8 atmospheres for 90 minutes, which resolved the problem with no adverse effects.     

高压氧综合治疗拔牙术后并发纵隔气性坏疽、脓胸一例

临床资料:患者,男性,40岁.2003年2月27日于当地卫生所拔除左上颌第三磨牙,术后第2天拔牙创面疼痛明显,逐渐出现左面颊部肿胀及张口受限,于2003年3月4日人我院口腔科.     

高压氧在四肢创伤治疗中的应用

对四肢多发创伤、骨折、神经损伤、软组织广泛挫伤实施高压氧治疗,应用显示结果良好,认为高压氧综合治疗可提高创伤的疗效.     

Recurrence in autogenous myocutaneous flap reconstruction after mastectomy for primary breast cancer: US diagnosis

PURPOSE: To assess the value of ultrasonography (US) and US-guided fine-needle aspiration biopsy (FNAB) in the detection and diagnosis of recurrent cancer in breasts reconstructed with autogenous myocutaneous flaps after mastectomy for primary breast cancer and to describe the US appearances of recurrence in the reconstructed breast. MATERIALS AND METHODS: Between July 1994 and March 2001, US of the reconstructed breast was performed in 20 women with autogenous myocutaneous flap reconstruction. US findings were correlated with clinical and mammographic findings. US-guided FNAB of 25 (64%) of the 39 recurrent cancers depicted at US was performed. RESULTS: Twenty-one (54%) of the 39 recurrent cancers depicted at US were clinically occult. Mammography performed in 12 of the 20 patients with reconstructed breasts depicted 14 (56%) of the 25 recurrent cancers that were detected at US in these patients. US-guided FNAB helped to establish a definitive diagnosis of recurrent breast carcinoma in 24 (96%) of the 25 tumor specimens sampled. CONCLUSION: US and US-guided FNAB are valuable for the assessment of both palpable and clinically occult recurrent breast cancers in autogenous myocutaneous flap breast reconstructions.     

Hyperbaric oxygen treatment time for cyclophosphamide induced cystitis in rats.

The aim of this study was to evaluate the prophylactic potential of hyperbaric oxygenation treatment and the timing of hyperbaric oxygen (HBO2) therapy for cyclophosphamide-(CYP) induced cystitis in rats. Forty male Sprague-Dawley rats were divided into 5 groups. Four groups received a single dose of CYP (100 mg/kg.) intraperitoneally (i.p.) at the same time (group 1 served as the control). Group 2 received CYP only; group 3 received HBO2 treatment (2.8 atmospheres absolute, 90 minutes, twice daily) before and the day after CYP. Group 4 received HBO2 before and on the day of CYP administration. Group 5 received HBO2 on the day of and the day after CYP. CYP injection resulted in severe cystitis. Prophylactic HBO2 treatment did not prevent the severe cystitis. After CYP injection, however, HBO2 treatment attenuated CYP-induced hemorrhagic cystitis in rats. Hyperbaric oxygen has a beneficial effect on repairing and healing bladder damage, though it does not function to prevent CYP-induced hemorrhagic cystitis.     

Hyperbaric oxygen therapy and optic neuritis: case report and literature review

A history of optic neuritis has long been considered a relative contraindication to hyperbaric oxygen therapy. However, the published medical literature regarding the use of hyperbaric oxygen therapy in patients with previous optic neuritis is very limited, and patients who might benefit from hyperbaric oxygen therapy may be denied its benefit without adequate consideration of the risk-benefit ratio. We present a case report of a patient with a history of optic neuritis who underwent comprehensive ophthalmologic evaluation before and after 40 treatments with hyperbaric oxygen therapy, with no detectable ophthalmologic deficit.     

MRI appearance of tumor recurrence in myocutaneous flap reconstruction after mastectomy

OBJECTIVE: The purpose of this perspective is to describe the role of breast MRI in the detection of local tumor recurrence in myocutaneous flap reconstructions and in the evaluation of extent of disease. CONCLUSION: Recognizing the MRI appearance of tumor recurrence in breast myocutaneous flap reconstructions is important for early detection of recurrence and in the evaluation of extent of disease to guide clinical management. Bilateral breast MRI for high-risk cancer screening of the native breast is a unique opportunity to detect recurrence in the reconstructed breast before it is clinically apparent. We describe a range of MRI appearances of breast cancer recurrence in patients with myocutaneous flap reconstructions.     

高压氧对迟发性放射损伤的作用

放射疗法是一种对肿瘤和周围正常组织均有显著作用的物理疗法,在放疗的同时,不可避免地会损伤正常组织导致放射损伤,特别是迟发性放射损伤,这将严重影响患者的生存质量。随着时间的推移迟发性放射损伤会发展得更加严重,甚至致死,因此限制了临床治疗时的放射剂量,目前这一问题并未得到解决。笔者主要就高压氧治疗对迟发性放射损伤的影响作一综述。     

Hyperbaric oxygen for delayed radiation injuries.

Hyperbaric oxygen has shown consistent benefit in treating patients with delayed radiation injury. It has also had success in preventing radiation injury in some instances. Additional study in identifying patients at risk for injury and delivering hyperbaric oxygen with prophylactic intent to prevent these injuries appears to be promising. Additional approaches to applying hyperbaric oxygen as a radiosensitizer also deserve further study. No convincing evidence exists to support concerns that hyperbaric oxygen enhances or stimulates malignant growth.