Aneurysmal bone cyst of the temporal bone

Aneurysmal bone cyst (ABC) of the temporal bone is rare. The nature of the underlying disorder that converted into the ABC might, however, be difficult to ascertain on imaging as well as on histopathology. The unusual CT and MRI findings in a case of ABC of the temporal bone are presented. This had transdural intracerebral spread with a large component of solid enhancing matrix but no peripheral calcific rim. The patient was an adult of 45 years with a history of headache for more than 1 year.     

Aneurysmal bone cyst of the temporal bone

Summary Aneurysmal bone cysts occurring within the calvarium are uncommon. The following case report describes the radiological and pathological findings of a temporal bone aneurysmal bone cyst with intra- and extracranial manifestations. The pertinent literature is reviewed.     

Aneurysmal bone cyst of the ethmoid bone

Aneurysmal bone cysts is a benign, slow growing expansile lesion usually found in long bones or vertebrae. Only 5 cases of ABC of the ethmoid bone have been reported in the literature. Plain radiographs are not specific. CT and MRI are very useful to depict the extent of the lesion and demonstrate the presence of blood-fluid levels, which is a characteristic finding of ABC. We present one atypical case of ABC of the ethmoid bone in a 15-year-old female characterised by its extensive involvement and its rare location.     

Aneurysmal bone cyst of the temporal bone

Aneurysmal bone cysts are benign fibrosseous lesions of the bone that are rarely detected in the temporal bone. Seventeen cases of aneurysmal bone cysts with histological confirmation involving the temporal bone were reported in the literature. We report a case of left temporal aneurysmal bone cyst in a 52-year-old male with the clinical findings of periauricular painful swelling, decreased hearing, and facial paralysis. A magnetic resonance image of the patient showed a well-circumscribed multi-loculated expansile lesion of the left temporal bone during the first admission to the hospital. The lesion recurred 1 year after the subtotal resection with a more solid appearance. In addition, we review the literature for these rare lesions.     

Aneurysmal bone cyst of the frontal bone

BACKGROUND: Aneurysmal bone cyst (ABC) is a benign, expansive, osteolytic lesion that mainly occurs in young people, and involves the skull bones only exceptionally. The origin of ABC is controversial: secondary reactive bone lesion, or primary disease that represents an independent nosological entity. Blunt head trauma was suggested as a possible etiological factor. CASE REPORT: A case of a 19-year-old man with primary ABC of the right frontal bone was reported. The lesion was totally excised through frontal craniotomy, and the skull bone defect primarily reconstructed with an acrilate cranioplasty. Five years after the surgery, the patient was without signs of local recurrence. CONCLUSION: Clinical and neuroradiological presentation of the skull ABC was not specific. Pathohistology confirmed the diagnosis. Total excision was the treatment of choice.     

异种脱蛋白骨修复山羊长骨大段缺损的成骨观察

目的 评估改良法制备异种脱蛋白骨(deproteinzated bone,DPB)作为组织工程支架材料修复大动物大段长骨缺损的能力,为异种DPB的临床应用提供实验依据.方法 山羊24只,在每只山羊右侧胫骨中下段截除胫骨总长度20%形成节段性骨缺损,按分组情况植入不同材料.A组为单纯异种DPB,B组为自体骨,C组为异种DPB+自体骨髓间充质干细胞(BMSCs)+重组人骨形态发生蛋白2(rhBMP2),均采用半环槽式外固定器固定.术后4～24周每隔4周进行X线及术后24周取新生骨进行双能X线(DEXA)、组织学、生物力学检测,评价骨缺损修复效果. 结果 术后4～24周,在同一时相点,X线Lane-Sandhu法评分B组》C组》A组,并且术后24周新骨的骨密度、骨矿含量、组织学和生物力学检测经统计学分析,C组与B组比较,差异无统计学意义(P>0.05). 结论 改良法制备的异种DBP复合自体BMSCs和rhBMP2修复山羊胫骨大段缺损成骨能力与自体骨相当,可以作为组织工程支架材料试用于临床.     

脱蛋白牛松质骨复合自体红骨随移植治疗骨缺损

骨缺损修复是骨科领域当前研究的重要课题,自体骨移植效果虽好,但来源有限,且增加供骨区损伤,而异体骨移植产生排斥反应等.长期以来,国内外学者一直对骨移植材料进行了大量的研究,以寻找自体骨的替代物.我们从1996-04～1999-06,试用脱蛋白牛松质骨加自体红骨髓复合植骨32例,取得满意效果,现介绍如下.     

术中富集骨髓细胞构建组织工程骨成骨能力的研究

目的 观察术中富集骨髓干细胞构建的组织工程骨在山羊脊柱横突间融合的成骨效果,为组织工程骨探索一种新型的构建方法.方法 将多聚左旋赖氨酸(poly-L-lysine,PLL)修饰于山羊脱钙骨基质(demineralized bone matrix,DBM)制备成基质材料(PLL-DBM);以山羊横突间隙为植骨模型,观察PIL-DBM富集骨髓细胞构建的组织工程骨(Ⅰ A组)的成骨能力;对照组为自体髂骨组(Ⅰ B组)、DBM富集骨髓组(Ⅱ C组)、空白DBM组(Ⅱ D组).于术后第16周取融合段标本行X线片、三维CT及CT值检测和生物力学检测,对比分析、评价其成骨能力.结果 X线表现:ⅠA组、Ⅰ B组融合范围基本相同,明显较ⅡC组宽,Ⅱ D组基本无融合.三维CT:Ⅰ A组的CT值为(696.76±102.75)HU,ⅠB组的CT值为(766.03±69.24)HU,二者差异无统计学意义(P>0.05),均明显较ⅡC组高(P<0.05),Ⅱ C组CT值较ⅡD组高(P<0.01).生物力学性能:Ⅱ A、Ⅰ B两组最大载荷、抗弯强度比较差异均无统计学意义(P>0.05),ⅠA组较Ⅱ C组高(P<0.01,0.05),Ⅰ B组较ⅡC组高(P<0.01),ⅡC组较ⅡD组高(P<0.01). 结论 PLL-DBM术中富集骨髓干细胞快速构建的组织工程骨是一种理想的组织工程骨,其成骨能力与自体髂骨相当.     

Giant-cell tumor of bone and aneurysmal bone cyst

A correlated histologic and radiographic study of nine giant-cell tumors, six aneurysmal bone cysts, and one combined lesion is presented. Clinical findings and plain radiographic appearances were found to overlap. Angiographically, the giant-cell tumors were richly vascularized, with a marked intratumoral contrast uptake, occasional irregular tumor vessles, a prominent peritumoral arterial net-work, and early draining veins. Microscopic examination revealed fine, capillary-like and somewhat larger, angulated, sinusoid vessels, and occasional small, bloodfilled cysts within the tumor. Conspicuous arteries, veins, and capillaries surrounded the tumor. The aneurysmal bone cysts at angiography were predominantly avascular in the interior, surrounded by a thin hyperemic zone in the peritumoral tissue, with sometimes early filling of veins. Microscopically, the aneurysmal bone cysts showed large, anastomosing, bloodfilled vascular channels, and a moderate number of capillaries within the solid, fibrous areas and the granulation tissue. It is concluded that angiography, particularly with a subtraction technique, may be a valuable diagnostic method in the pre-operative differentiation of giant-cell tumors from aneurysmal bone cysts.     

Solid aneurysmal bone cyst with pathologic bone fracture

Presented at the 17th Annual Meeting of the International Skeletal Society in Salzburg, Austria, September 1990     

Radionuclide bone image in growing and stable bone island

A normal radionuclide bone image can facilitate distinction between a bone island and significant pathologic processes, especially an osteoblastic metastasis. This distinction becomes more crucial when growth is detected in an isolated sclerotic bone lesion or if a relatively large sclerotic lesion is detected de novo in patients with a known neoplasm. This report presents three patients with isolated bone islands: two with interval growth, the other with a relatively large stable lesion; all showing a normal radionuclide bone image.     

选择性雌激素受体调节剂雷诺昔酚对去势后大鼠骨密度及股骨生物力学的影响

目的：观察选择性雌激素受体调节剂（SERM）雷诺昔酚（raloxifene）对去势后大鼠骨密度及股骨生物力学的影响。方法：将5月龄未经产雌性二级SD大鼠24只，随机分为3组，每组8只：A组为假手术（SHAM）组；B组为去势（VOX）组；C组为去势＋雷诺昔酚（V0x＋RAL）组。C组大鼠术后第7d开始给药。术后16w处死各组大鼠，对各组大鼠骨密度（BMD）、骨生物力学指标进行检测，并进行骨组织形态学观察。结果：（1）去势组与对照组比较，去势组股骨近端、股骨干、腰椎BMD明显降低（P．〈0．01）；雷诺昔酚治疗组各部位BMD高于去势组（P〈0．05），但没有恢复到SHAM组水平（P〈0．05）；（2）与Sham组比较，去势组大鼠骨的股骨最大载荷、桡度、最大应力、弹性模量均明显下降（P〈0．05），雷诺昔酚治疗组上述指标高于去势组（P〈0．05），接近对照组水平。结论：去势后16w大鼠松质骨、皮质骨骨量、骨组织形态计量学及生物力学指标均明显下降。雷诺昔酚治疗后大鼠松质骨，皮质骨密度得到较好维持，雷诺昔酚对骨组织形态计量学及生物力学状况有显著改善作用，可减少和抑制骨质疏松性骨折的发生。     

Bone scan appearances following biopsy of bone and bone marrow

The influence of sternal marrow aspiration, iliac crest marrow aspiration, and iliac crest bone biopsy on bone scan appearances was examined. Eighteen patients were scanned a mean of 9.9 days after sternal marrow aspiration with a Salah needle (diameter 1.2 mm). Only one patient had an abnormality at the biopsy site. Bone scans obtained in 9 patients a mean of 10 days after iliac crest trephine marrow biopsy with a Jamshidi needle (diameter 3.5 mm) showed no abnormality at the biopsy site. In 18 patients with metabolic bone disease who had undergone iliac crest bone biopsy with an 8-mm needle, a scan abnormality due to the biopsy was usually present when the interval between the biopsy and the scan was 5 days to 2 months. Patients who were scanned within 3 days of iliac crest bone biopsy or more than 2 months after biopsy had normal scan appearance at the biopsy site.     

Polyphosphate bone scanning of non-malignant bone disease in children.

The advent of 99mTechnetium phosphate bone scanning radiopharmaceuticals has opened new methods of investigation of pediatric bone diseases. In axial skeleton pain, suspected osteomyelitis, evaluation of vascular integrity and suspected but undetected fractures, the bone scan has proved to be a highly complementary study to the radiologic examination.