Impact of radiofrequency assisted hepatectomy for reduction of transfusion requirements

BACKGROUND: Liver parenchyma transection technique using heat coagulative necrosis induced by radiofrequency (RF) energy is evaluated in this series. METHODS: Between January 2000 and October 2004, 156 consecutive patients underwent liver resection with the RF-assisted technique. Data were collected prospectively to assess the outcome, including intraoperative blood loss, blood transfusion requirement, and morbidity and mortality rates. RESULTS: There were 30 major hepatectomies and 126 minor resections. While total operative time was 241 +/- 89 minutes, the actual resection time was 75 +/- 51 minutes. Intraoperative blood loss was 139 +/- 222 mL. Nine patients (5%) received blood transfusion, predominantly those receiving major hepatectomy (P = .006). Thirty-six patients (23%) developed postoperative complications, and the mortality rate was 3.2%. Mean hospital stay was 12 +/- 12 days. CONCLUSION: The RF-assisted technique is associated with minimal blood loss, a low blood transfusion requirement, and reduced mortality and morbidity rates and can be used for both minor and major liver resections.     

Bloodless liver resection using radiofrequency energy

BACKGROUND: Liver surgery carries the risk of intraoperative bleeding. In order to avoid bleeding, transection of the liver can be performed after coagulating the parenchyma by using monoplolar or bipolar radiofrequency energy. METHODS: 236 consecutive patients underwent liver resection with the radiofrequency-assisted technique using either a monopolar or a bipolar device. Data were collected prospectively to assess the outcome including, intraoperative blood loss, blood transfusion requirement, morbidity and mortality rates. RESULTS: There were 41 major hepatectomies and 195 minor resections. Overall mean intraoperative blood loss was 157 +/- 240 ml, while mean blood loss during liver transection was 90 +/- 105 ml. 10 patients (4%) received blood transfusion. 50 patients (21%) developed postoperative complications including 5 bile leaks (2%). The mortality rate was 2.1%. No patient was reoperated for postoperative haemorrhage or bile leak. The mean postoperative stay was 11 +/- 10 days. CONCLUSION: The radiofrequency-assisted liver resection technique offers hepatobiliary surgeons an additional method for performing liver resections with minimal blood loss, low transfusion requirement, and low morbidity and mortality rates.     

Surgical treatment of benign hepatic mass lesions

Benign hepatic mass lesions may require surgical treatment for symptomatic relief or prevention of hemorrhage. The most common benign hepatic mass lesions in the United States are hemangioma, focal nodular hyperplasia, hepatic adenoma, and congenital liver cyst. We report a series of liver resections performed for benign hepatic masses at our institution. All liver resections were performed with total inflow occlusion during the parenchymal transection time. None of our patients received perioperative blood products. No postoperative complications occurred, and the average length of hospital stay was 6 days. Surgeons performing hepatic resections for benign mass lesions should be able to complete these procedures with low operative blood loss and low operative morbidity.     

机器人肝切除术：附17例报告

目的：总结机器人手术系统在肝脏切除术应用中的临床经验。方法：对于2009年1月至2010年7月实施的17例机器人外科手术系统所行肝切除术的资料进行回顾性分析。结果：17例机器人肝脏手术病人中男∶女=8：9,平均年龄（55±16）（27～85）岁。包括原发性肝细胞癌3例;胆管细胞癌3例（BismuthⅢb型肝门部胆管癌1例,肝内胆管囊腺癌2例）;转移性肝癌3例;良性肝脏肿瘤4例（肝血管瘤3例,胆管囊腺瘤1例）;左肝内胆管结石4例。手术方式：规则性左半肝切除术2例,左肝外叶切除术5例,肝局部或楔形切除7例,亚肝段（s5a）切除术1例,联合其他机器人术式12例。机器人肝切除的平均手术时间为280 min,术中出血量为150 mL。术中发生大出血3例,其中2例（11.8%）为巨大肝血管瘤中转开腹切除。采用Pringle法肝切除4例,采用肝实质缝扎和超声刀离断肝实质交替法实施左肝外叶切除4例。机器人肝切除病例的平均住院时间为7（5～16）d。术后发生严重并发症2例（11.8%）：腹腔内出血1例,肺部感染1例,经保守治疗治愈,无胆漏等严重并发症和围手术期死亡。结论：机器人肝切除术安全、可行,疗效确切。探索适合机器人手术系统优势的肝切除止血方法等创新性技术将是今后机器人肝切除的重点之一。     

Laparoscopic Liver Resection

More than 3,000 laparoscopic liver resections (LLR) are performed worldwide for benign disease, malignancy, and living donor hepatectomy. Minimally invasive hepatic resection approaches include pure laparoscopic, hand-assisted laparoscopic, and a laparoscopic-assisted open “hybrid” approach, where the operation is started laparoscopically to mobilize the liver and begin the dissection, followed by a small laparotomy for completion of the parenchymal transection. Surgeons should have an advanced understanding of hepatic anatomy, extensive experience in open liver surgery, and technical skill to control major vascular and biliary structures laparoscopically before embarking on LLR. Although there is no absolute size criterion, smaller, peripheral lesions (<5 cm) that lie far from major vessels and anticipated transection planes are most amenable to LLR. Although the majority of reported LLR are non-anatomic resections or segmentectomies, several surgical groups are now performing laparoscopic major hepatic resections with excellent safety profiles. Patient benefits from LLR include less operative blood loss, less postoperative pain and narcotic requirement, and a shorter length of hospital stay, with comparable postoperative morbidity and mortality to open liver resection. Comparison studies between LLR and open resection have revealed no differences in width of resection margins for malignant lesions or overall survival after resection for hepatocellular cancer or colorectal cancer liver metastases. Advantages of LLR for HCC in particular include avoidance of collateral vessel ligation, decreased postoperative hepatic insufficiency, and fewer postoperative adhesions, all of which are features that enhance subsequent liver transplantation.     

Safety of donor right hepatectomy without abdominal drainage: a prospective evaluation in 100 consecutive liver donors.

Although the role of routine abdominal drainage after liver resection for tumors has been questioned, abdominal drainage after donor right hepatectomy for live donor liver transplantation (LDLT) has been a routine practice in most transplant centers. The present study aimed to evaluate the safety of the procedure without abdominal drainage. A prospective study was performed on 100 consecutive liver donors who underwent right hepatectomy for LDLT from July 2000 to September 2003. Biliary anatomy was carefully studied with intraoperative cholangiography using fluoroscopy. The middle hepatic vein was included in the graft in all except 1 patient. Parenchymal transection was performed using an ultrasonic dissector. The right hepatic duct was transected at the hilum and the stump was closed with 6-O polydioxanone continuous suture. Absence of bile leakage was confirmed with methylene blue solution instilled through the cystic duct stump. The abdomen was closed after careful hemostasis without drainage in all donors. The median age of the donors was 36 years (range 18-56 years). Median operative blood loss and operating time were 350 mL (range 42-1,400 mL) and 7.5 hours (range 5.2-10.7 hours), respectively. None of the donors required any blood or blood product transfusion. There was no operative mortality. The median postoperative hospital stay was 8 days (range 5-30 days). Postoperative morbidity occurred in 19 patients (19%), most of which were minor complications. No donor experienced bile leakage, intraabdominal bleeding, or collection. None required surgical, radiologic, or endoscopic intervention for postoperative complications, except for 1 donor who developed late biliary stricture that required endoscopic dilatation. All donors were well with a median follow-up of 32 months (range 11-50 months). In conclusion, with detailed study of the biliary anatomy and meticulous surgical technique, donor right hepatectomy can be safely performed without abdominal drainage. Abdominal drainage is not a mandatory procedure after donor hepatectomy in LDLT.     

Usefulness and Application of the Liver Hanging Maneuver for Anatomical Liver Resections

BACKGROUND: To achieve complete anatomic hepatectomy, hepatic transection by an anterior approach is useful. The liver hanging maneuver is a useful procedure for transection of adequate cut plane in anatomical liver resections and may reduce intraoperative bleeding and transection time. METHODS: We examined the records of 71 patients who underwent anatomic hepatic resection with (n = 24, between 2001 and September 2007) or without liver hanging maneuver (LHM) (n = 47, between 2000 and 2003). Groups were historically compared in terms of patient demographics, preoperative hepatic function, surgical records, and outcome. LHM was conducted according to the Belghiti's original method. RESULTS: LHM could be performed not only in hemihepatectomy but also in right and left trisectionectomy. Demographics and preoperative hepatic function tests were not significantly different between the LHM and non-LHM groups. Although intraoperative bleeding, blood transfusion, and operating time were not significantly different between groups, the time required for liver parenchymal transection was significantly shorter in the LHM group (36.5 +/- 9.9 vs. 48.1 +/- 12.7 min, P = 0.004). Postoperative liver function, morbidity, and mortality were not significantly different between the groups. In other hepatectomy with cut plane along the right hepatic vein, the transection time tended to be shorter in the LHM group (n = 5, 32.4 +/- 6.1 min) than in the non-LHM group (n = 5, 44.4 +/- 8.3 min), albeit insignificantly (P = 0.06). CONCLUSION: LHM can reduce the transection time at the cut plane in hepatic resections. Our results emphasized the advantages and usefulness of LHM in anatomical liver resections.     

Lung resection for cancer in patients with coronary arterial disease: analysis of short-term results.

OBJECTIVE: Patients with lung cancer may present concomitant coronary arterial disease. Feasibility of lung resection is dependent on the severity of the cardiac impairment since it can increase operative morbidity and mortality. The aim of this study was to analyze the results of lung resection in patients with coronary arterial disease in terms of operative complications and hospital stay. METHODS: Between January 1993 and March 2001, 50 patients with coronary arterial disease underwent lung resection for cancer at our department. Nineteen patients with a curable left-main or multiple-vessel disease first underwent surgical (six patients) or transluminal (13 patients) myocardial revascularization. Twenty-two of the 31 patients who did not require myocardial revascularization presented a medium-high cardiac risk. Univariate analysis determined the impact of coronary disease on operative complications and hospital stay. RESULTS: Surgery consisted in 40 lobectomies, three pneumonectomies and seven wedge resections. The overall mortality and morbidity rates were 4% and 28%, respectively. Ten patients (22%) experienced postoperative cardiac complications such as arrhythmia and there was one intraoperative death, three suffered secretion retention and one patient died as a consequence of a stroke. Occurrence of postoperative complications was influenced by age (P=0.02) and the presence of medium-high cardiac risk (P=0.03). Hospital stay was longer for patients who did not have prior myocardial revascularization (11.7+/-4 vs. 8.1+/-3 days) and underwent more extensive pulmonary resection (10.6+/-5 vs. 7.4+/-2 days). CONCLUSIONS: Lung resection in patients with coronary arterial disease is justified in selected cases. Previous myocardial revascularization and limited resections can decrease operative complications and hospital stay. Careful preoperative evaluation can identify patients who might benefit from myocardial revascularization prior to surgery.     

Early outcomes of 100 patients with laparoscopic resection for rectal neoplasm

Background Laparoscopic resection has been shown to be a feasible option in patients with colorectal diseases. However, there have been only a few studies on laparoscopic resection for rectal neoplasm. This report aimed to evaluate the early outcomes of patients treated by laparoscopic rectal resection for neoplasm. Methods From May 2000 to April 2003, 100 patients underwent laparoscopic resection for rectal neoplasm with mesorectal excision. Data on the patients' demographics, operative details, and outcomes were collected prospectively. In those with successful laparoscopic resection, comparison was made between patients with predominantly intracorporeal surgery (ICS) and those with anterior resection performed with extracorporeal rectal transection and anastomosis following intracor-poreal bowel mobilization and vessel ligation (IECS). Results Sixty-six men and 34 women (median age, 69 years; range, 40–85) were included. Operations included 91 anterior resections, eight abdominoperineal resections, and one Hartmann's procedure. Conversion was required in 15 patients and no conversion was needed in patients treated by laparoscopic abdomino-perineal resection. One patient died 30 days after surgery because of liver failure. Postoperative complications occurred in 31 patients. Among them, three had anastomotic leakage and all of them could be treated conservatively. Reoperation was required in one patient with intestinal obstruction. Patients with conversion were found to have significantly more blood loss, longer time to resume diet, a longer hospital stay, and a higher morbidity rate when compared to those with successful laparoscopic surgery. Among those with successful laparoscopic procedures, no difference was observed between patients with ICS (n=57) and those with IECS (n=28), except that a shorter incision and less blood loss were found in patients in the former group. Conclusions Laparoscopic rectal resection with mesorectal dissection is feasible. The operating mortality and reoperation rates were low. Conversion was associated with an increased morbidity rate, leading to a longer hospital stay. Laparoscopically assisted anterior resection with rectal transection by a transverse stapler through the abdominal incision produced similar results when compared to a procedure that was predominantly intracorporeally performed     

射频凝血器在肝切除术中的应用价值

目的：探讨射频凝血器在肝切除术中临床疗效和应用价值。
　　方法：回顾性分析2011年7月—2013年7月行肝切除手术108例患者的临床资料,其中41例行射频凝血器断肝（观察组）,67例应用传统钳夹法断肝（对照组）,比较两组的临床效果。
　　结果：与对照组比较,观察组手术时间、术中出血量、输血患者比例及肝门阻断比例均少于对照组;术后转氨酶和胆红素上升数值、腹腔引流量及住院时间均低于对照组,差异均有统计学意义（均P<0.05）。两组间术后并发症发生率及总住院费用差异无统计学意义（均P>0.05）。
　　结论：应用射频凝血器可有效减少出血,降低对肝脏损害,缩短住院时间,且不明显增加住院费用,在肝切除中有应用价值。     

手助腹腔镜肝癌切除23例

目的探讨手助腹腔镜肝癌切除的可行性和安全性。方法对病变位于肝脏外周部位(Ⅱ~Ⅵ段)的23例病人,肝细胞癌20例,肝内胆管细胞癌2例,肝囊腺癌1例。采用手助腹腔镜行肝切除术。结果23例手助腹腔镜肝切除均获得成功,规则性肝叶(段)切除17例,肝不规则切除6例,平均手术时间为105 m in,平均出血量187 m l,术后无严重并发症发生,术后平均住院日为9.5 d。结论手助腹腔镜肝切除是安全可行的,缩短手术时间,减少出血的微创手术方式。     

复发性肝癌的腹腔镜再切除

目的探讨腹腔镜肝切除术(LH)治疗复发性肝癌的安全性及可行性。方法 2003年8月至2008年5月,同一手术组完成大约500例肝癌切除手术,其中LH120例。500例患者中,约有100例复发,我们仔细选择6例病例进行了腹腔镜复发性肝癌再切除术,手术适应证评估指标包括肿瘤位置、大小、转移范围、血管侵犯与否以及肝功能状况等。手术方式包括4例局部切除及2例解剖性左外叶切除。对病例资料进行回顾性分析。结果 6例手术均取得成功,无严重术中及术后并发症发生。平均手术时间为(140.8±35.7)min,平均出血量为(283.3±256.3)ml,术后平均住院日为(5.7±1.6)d。结论对于严格选择的病例,LH是治疗复发性肝细胞癌的一种安全有效的方法,具有创伤小、恢复快的优点。     

Glisson蒂横断法在腹腔镜左肝段切除术中的应用

目的:探讨应用Glisson蒂横断法行腹腔镜左肝段切除术的可行性及技术要点。方法:回顾分析2015年1月至2016年10月为14例患者行腹腔镜下Glisson蒂横断法左肝段切除术的临床资料。观察手术时间、术中出血量、住院时间、术后并发症、近期及远期疗效等指标。结果:14例患者均成功施行腹腔镜下Glisson蒂横断法左肝段切除术,无一例中转开腹,其中肝左外叶切除5例、左半肝切除4例,Ⅱ、Ⅲ段肝切除各2例,Ⅳ段肝切除1例。手术时间100~240 min,平均(140.6±89.3)min;术中出血量150~300 ml,平均(200.5±95.7)ml;住院5~10 d,平均(7.8±2.4)d;无手术并发症发生,随访早期无肿瘤复发与转移。结论:腹腔镜下Glisson蒂横断法左肝段切除术的优势在于迅速、精确的到达Glisson蒂左肝段分支,适于左半肝、左外叶及Ⅱ、Ⅲ、Ⅳ段的肝肿瘤,手术安全、可行,可在很大程度上简化腹腔镜肝段切除术。     

Making liver transection even safer: a novel use of microwave technology

Hepatic surgery has evolved significantly in the past decade. The current article describes the largest series of patients in United States undergoing liver resective therapy with the use of microwave technology for liver precoagulation. Glisson's capsule was incised after securing inflow and outflow control. Two antennae, 2 cm apart, connected to a 915-MHz generator, were inserted 5 cm into liver parenchyma at a 130° angle. Once the parenchyma was firm and changed its color to gray, the antennae were advanced along the line of transection. The parenchyma was divided with electrocautery. Intra- and postoperative data were analyzed. Thirty-five patients (24 men) underwent liver resections. Diseases treated were colorectal metastases (n = 9), hepatic adenoma (n = 3), gallbladder cancer (n = 3), hepatocellular carcinoma (n = 4), neuroendocrine tumor (n = 2), cholangiocarcinoma (n = 5), hemangioma (n = 2), focal nodular hyperplasia (n = 2), metastatic gastrointestinal stromal tumor (n = 1), hydatid cyst (n = 1), hepatoid carcinoma (n = 1), hepatolithiasis (n = 1), and suspected metastatic breast cancer (n = 1). Resections done were right hepatectomy (n = 19), segmental resection (n = 5), left hepatectomy (n = 4), extended right hepatectomy (n = 4), Segment IVb and Segment V resections during radical cholecystectomy (n = 2), and left lateral sectionectomy (n = 1). Median operative time for major resection was 188 and 251 minutes for minor resection. There was one postoperative mortality. Bile leak needing stenting occurred in one patient. Median blood loss for major resection was 500 mL and 265 mL for minor resection. Intraoperative transfusion was required in nine major and one minor resections. Other complications were ileus in four, deep vein thrombosis in two, intra-abdominal abscess in one, and cardiac events in two patients. Liver precoagulation with microwave technology is a novel and efficient technique with minimal morbidity and mortality for liver transection.     

Morbidity of major hepatic resections: a 100-case prospective study.

OBJECTIVE: To assess the morbidity and its main risk factors after major hepatic resection. DESIGN: Retrospective study of prospectively collected data. SETTING: University hospital, France. SUBJECTS: 100 consecutive patients who underwent major hepatic resections, 1989-95. INTERVENTIONS: Major hepatic resection, defined as resection involving 3 or more segments according to Couinaud's classification, in all cases. MAIN OUTCOME MEASUREs: All complications that affected outcome or prolonged hospital stay. Risk factors identified by univariate and multivariate analysis. RESULTS: 45 patients developed at least 1 complication and 7 died. The most common complications were: pleural effusion (n = 21), hepatic failure (n = 12), and ascites (n = 9). Univariate analysis showed that the following variables were significantly related to the morbidity: age >55 years, American Society of Anesthesiologists (ASA) grade II or more, bilirubin >80 micromol/L, alkaline phosphatase activity more than double the reference range, malignant tumours, abnormal liver parenchyma, simultaneous surgical procedures, operative time >4 hours, and perioperative blood transfusion > or =600 ml. The extent of resection did not correlate with postoperative complications. Multivariate analysis showed that volume of blood transfusion > or =600 ml and simultaneous surgical procedures were the most important independent risk factors for complicated outcome. CONCLUSIONS: The morbidity associated with major hepatic resections remains high, and the main determinants of outcome are intraoperative surgeon-related factors.     

Intra-operative Blood Loss Predicts Complications After a Second Hepatectomy for Malignant Neoplasms

Objective We investigated the risk of morbidity after repeat resections for liver recurrence of hepatocellular carcinoma or for colorectal liver metastases. Background Data Although repeat hepatectomy for recurrences of hepatocellular carcinoma or for colorectal cancer liver metastases is well known only to carry risks similar to those seen for an initial liver resection, the safety of such a procedure is questionable because, typically, only a few liver tumors are thought suitable for repeat hepatectomy. Methods Clinicopathology data were available for 412 hepatectomy patients (hepatocellular carcinoma in 226, colorectal liver metastases in 186). Risk factors for postoperative complications were analyzed retrospectively among the 57 patients undergoing a repeat hepatectomy. Results Using multivariate analysis, intraoperative blood loss (relative risk, 9.61; P = 0.02) affected the occurrence of postoperative complications after a second hepatectomy. In patients who lost more than 1.29 l blood intraoperatively at the second hepatectomy, a major hepatectomy (P < 0.05) by means of an anatomical type of resection (P < 0.01) was more often performed than in the patients with 1.29 l or less of blood loss. Conclusions The major independent risk factor associated with complications after a second hepatectomy for liver recurrence was intraoperative blood loss. The extent of liver resection, especially in an anatomical manner, directly influences the amount of blood loss.     

完全腹腔镜肝部分切除术临床体会

目的总结20例完全腹腔镜肝切除术手术经验,阐述其技术要点和效果。方法回顾性分析2011年4月至2013年11月间我院20例完全腹腔镜肝切除术患者的临床资料。其中肝左叶部分切除15例,肝右叶部分切除5例。术前应用肝功能Child分级、ICGR15评估肝储备功能及cT三维成像评估肝肿瘤周围血管情况,术中根据肝脏病灶部位选择手术径路,应用超声刀、钛夹、LigaSure、Endo—GIA等多种断肝方法行完全腹腔镜肝部分切除。结果20例患者均成功施行完全腹腔镜下肝部分切除术,手术时间105—215min,出血量50～500ml,术中未出现严重并发症,术后均顺利恢复,术后平均住院日为7．5d。除2例原发性肝癌患者分别于术后随访5个月、12个月发现肿瘤复发外,其余原发性肝癌患者尚未见复发,良性病变患者无症状再发。结论术前进行肝功能及影像学评估、术中选择合适的手术入路及灵活应用各种断肝器械是成功施行完全腹腔镜肝部分切除术的保证。     

A prospective evaluation of ultrasonic dissector plus harmonic scalpel in liver resection

Several techniques have been described for safe dissection of the liver parenchyma. The aim of this study was to evaluate the feasibility and effectiveness of combining two different electronic devices, the ultrasonic dissector and the harmonic scalpel, during hepatic resection. One hundred consecutive patients who underwent liver resection between January and December 2004 were enclosed in the study. Patients requiring concomitant colic resection or biliary-enteric anastomosis were excluded from the study. Operative variables (type of procedure, operating time, Pringle time, blood losses, transfusions, and histological tumor exposure at the transection surface), hospital stay, and complications were recorded. The extent of hepatic resection was a minor resection in 31 and major in 69 cases. Median blood loss was 500 mL (range, 100-2000 mL) and the Pringle maneuver was used in 58 patients. Median operative time was 367 minutes (range, 150-660 minutes). Hepatic resection was performed in 32 cirrhotic livers. Surgical complications included one postoperative hemorrhage and two bile leaks. The overall morbidity and mortality rate was 14 and 1 per cent, respectively. In conclusion, the combined use of these electronic devices allows liver resection to be safely performed, even in cirrhotic patients, with the advantage of reducing surgical complications. A prospective randomized trial is needed to clarify the clinical benefits of liver resections performed combining these two devices.     

Major hepatic resection. A 25-year experience.

Major hepatic resections were performed on 138 patients for a variety of conditions. There was one intraoperative death. Including this patient, there were 15 deaths within 30 days of the operation (operative mortality 10.9%). Important postoperative complications were intra-abdominal sepsis (17%), biliary leak (11%), hepatic failure (8%), and hemorrhage (6%). The results of 30 resections for the benign lesions, liver cell adenoma, focal nodular hyperplasia, hemangioma, and cystadenoma showed no operative mortality and low morbidity. Of 26 patients with hepatocellular carcinoma, seven died within a month of operation. The cumulative survival of the 26 at five years was 38%, and of the 19 who survived the procedure, 51%. Poor survival followed resections for cholangiocarcinoma and "mixed tumors." The five-year cumulative survival of 22 patients who had colorectal metastases excised was 31%. Apart from a patient with carcinoid, prolonged survival was rare after resection of other secondaries and after en bloc resections for tumors directly invading the liver. Hepatic resection was of value in the management of some patients with hepatic trauma, Caroli's disease, liver cysts, and intrahepatic stones.     

腹腔镜肝癌切除术中应用射频凝血器断肝的价值

目的:评价腹腔镜肝癌切除术中应用射频凝血器断肝的临床效果。方法:回顾性分析2011年7月—2015年12月行完全腹腔镜肝癌切除手术45例患者的临床资料,根据断肝器械不同将患者分为观察组(20例,射频凝血器断肝)和对照组(25例,超声刀断肝),比较两组相关临床指标。结果:观察组与对照组比较,手术时间无统计学差异(P0.05);术中出血量[(325.00±111.80)m L vs.(628.00±119.09)m L)]、输血患者比例(3/20vs.11/25)、术后24 h腹腔引流量[(110.00±57.95)m L vs.(334.40±209.56)m L]均明显降低(均P0.05);术后肝功能指标、住院时间、并发症发生率及住院费用均无统计学差异(均P0.05);术后总生存率(75.0%vs.72.0%)差异无统计学意义(P0.05),但无瘤生存率(75.0%vs.36.0%)明显升高(P0.05)。结论:在腹腔镜肝癌手术中,应用射频凝血器断肝可有效减少出血,减少术后并发症,提高无瘤生存率,近期效果优于术中使用超声刀者。