逆行腓肠神经营养血管皮瓣的临床应用体会

目的 研究逆行腓肠神经营养血管皮瓣修复小腿胫前区及足部创伤的临床效果.方法 我科2009年9月~2012年11月应用逆行腓肠神经营养血管皮瓣修复小腿胫前及足部软组织缺损19例,其中4例合并Ⅱ型糖尿病,3例合并慢性骨髓炎及窦道形成.皮肤缺损面积8 cm×5 cm～17 cm×11 cm.结果 本组17例术后皮瓣存活良好,伤口一期愈合.1例术后皮瓣因引流不充分出现积血致远端部分坏死,行二期皮片移植术后愈合;1例因皮瓣蒂部软组织挫伤致血供不良改行交腿皮瓣后愈合.结论 逆行腓肠神经营养血管皮瓣可切取范围较大,血供丰富,解剖容易,不易损伤大血管,蒂部旋转灵活,能修复的创面部位较多,皮瓣成活率高.     

腓肠神经营养血管蒂逆行岛状皮瓣的临床应用

目的:探讨应用腓肠神经营养血管蒂逆行岛状皮瓣修复小腿下端、踝周和足部皮肤软组织缺损的可靠性.方法:对18例小腿下端、踝周和足部皮肤软组织缺损病人选择腓肠神经营养血管蒂逆行岛状皮瓣修复,皮瓣最大17cm×11cm、最小6cm×5cm.结果:皮瓣Ⅰ期愈合15例,Ⅱ期愈合3例.随访6个月～2年,皮瓣质地、颜色良好.结论:腓肠神经营养血管蒂逆行岛状皮瓣血管蒂恒定,层次清晰,操作简单,皮瓣不牺牲主干血管,对小腿功能和外形影响小,皮瓣转移幅度大,是修复小腿中下段、踝周、足跟等软组织缺损的良好修复方式.     

腓肠神经营养血管蒂皮瓣交腿修复胫前及足部软组织缺损

目的探讨腓肠神经营养血管蒂皮瓣交腿修复胫前及足部软组织缺损的临床疗效。方法2004年1月～2007年12月,对11例胫前及足部外伤感染后软组织缺损坏死、骨外露彻底清创后,采用腓肠神经营养血管蒂皮瓣交腿修复,胫前软组织缺损6．0cm×5．0cm～16．0cm×8．0cm;足部软组织缺损4．0cm×3．0cm～14．0cm×6．8cm,皮瓣切取范围为5．6cmX4．5cm～18．0cm×10．0cm,蒂最长达18cm。结果术后10例皮瓣Ⅰ期愈合,1例Ⅱ期愈合。随访3个月～3年,质地良好,外观较满意。足背皮瓣中1例边缘坏死,1例老年患者出现下肢交腿压疮,浅部针眼感染2例。膝、踝关节功能受影响小,皮瓣感觉仅有少部分恢复。结论腓肠神经营养血管蒂皮瓣交腿是修复胫前及足部软组织缺损的有效方法。老年患者固定时间长容易引起关节僵硬,宜慎用,交腿后注意固定及防止压疮。     

顺行腓肠神经营养血管皮瓣修复小腿上段胫骨外露创面的临床应用

目的 探讨顺行腓肠神经营养血管皮瓣修复小腿上段胫骨外露创面的疗效.方法 回顾性分析2017年11月—2019年12月苏州大学附属第一医院烧伤整形外科收治小腿上段胫骨外露患者12例,男性9例,女性3例;年龄20～64岁,平均41.5岁;道路交通伤4例,机械伤3例,碾压伤2例,撕脱伤3例.创面面积5cm×4cm～9cm×3cm.合并胫骨骨折6例,创面均采用顺行腓肠神经营养血管皮瓣修复.结果 皮瓣全部成活10例,皮瓣切取面积6cm×5cm～19cm×7cm;皮瓣远端边缘部分坏死2例,经换药后愈合.术后随访2～8个月,平均4.5个月.皮瓣外形满意,痛觉、触觉恢复较满意.结论 顺行腓肠神经营养血管皮瓣修复小腿上段胫骨外露创面手术操作简单、不牺牲知名血管腓动脉,疗效满意,值得临床推广应用.     

腓肠神经营养血管皮瓣与小腿内外侧皮瓣修复足踝部创面对比研究

目的 比较足踝部创面修复术中使用腓肠神经营养血管皮瓣与小腿内外侧皮瓣的效果.方法 足踝部创伤30例,缺损范围3 cm×6 cm～30 cm×15 cm,随机分为腓肠神经营养血管皮瓣修复组(A组)和小腿内外侧皮瓣修复组(B组),每组各15例,所有供区直接缝合或植皮封闭.结果 患者均获随访,随访时间3～6个月,A组无并发症,皮瓣质地优良,外观功能满意,修复创面最大30 cm×15 cm,供区创面封闭好;B组5例远端1/3坏死,植皮后愈合,修复创面最大18 cm×10 cm,3例供区创面植皮成活差,5例修复足背创面的皮瓣张力大,瘢痕重.结论 腓肠神经营养血管皮瓣修复足踝创面效果优于小腿内外侧皮瓣.     

逆行腓肠神经营养血管筋膜皮瓣临床应用体会

目的总结逆行腓肠神经营养血管筋膜皮瓣临床应用经验。方法回顾2003年至2007年临床应用的10例逆行腓肠神经营养血管筋膜皮瓣修复小腿下部组织缺损的临床资料。结果10例皮瓣安全存活,皮瓣切取最大面积可达25cm×12cm,最小面积4cm×4cm,可修复小腿、内外踝部、足跟部、足背部创面。手术方法安全性大,效果优良。结论逆行腓肠神经营养血管筋膜皮瓣,手术设计、操作简便,易于切取,不牺牲小腿主要动脉,不吻合血管,且皮瓣成活率高。     

逆行腓肠神经营养血管皮瓣修复踝区Ⅳ度烧伤创面(附14例报告)

目的 探讨应用逆行腓肠神经营养血管皮瓣修复踝区Ⅳ度烧伤创面的临床效果.方法 应用远端蒂逆行腓肠神经营养血管皮瓣修复踝区Ⅳ度烧伤创面14例,创面范围5cm×4cm～12cm×6cm,皮瓣大小6cm×5cm～14cm×7cm,皮瓣最大旋转180°.自体中厚皮移植覆盖供瓣区及蒂部创面.观察皮瓣成活及腓肠神经分布区皮肤感觉情况.结果 14例皮瓣全部成活,1例术后早期出现轻度静脉淤血,抬高患肢后缓解.13例移植皮瓣Ⅰ期愈合,1例缝合口少部分裂开,经换药治疗17d愈合.供皮区及供瓣区均Ⅰ期愈合.所有患者术后短期内均有腓肠神经分布区感觉缺失.随访3～48个月,皮瓣质地柔软,修复区外形满意,不影响功能,腓肠神经分布区皮肤感觉恢复,无痛性神经瘤发生.结论 逆行腓肠神经营养血管皮瓣血供可靠、损伤小,是修复踝部Ⅳ度烧伤创面的理想方法.     

腓肠神经营养血管皮瓣修复小腿及足踝部软组织缺损

目的：观察腓肠神经营养血管皮瓣转位修复小腿及足踝部软组织缺损的效果。方法：设计带筋膜蒂的腓肠神经营养血管皮瓣，逆行转位修复小腿及足踝部软组织缺损15例，观察皮瓣成活情况及治疗效果。结果：本组15例中2例皮瓣部分坏死，其余全部一次成活。结论：腓肠神经营养血管皮瓣创伤小，手术简单，血供可靠，是修复小腿及足踝部软组织缺损的理想皮瓣。     

超长腓肠神经营养血管皮瓣的临床应用

目的探讨延迟转移超长腓肠神经营养血管皮瓣的临床应用效果。方法对5例伴有肌腱、骨质等深部重要组织外露的创伤患者行超长腓肠神经营养血管皮瓣转移治疗,皮瓣切取前2周,在腘窝平面下小腿后侧上1/3做延迟倒"U"形切口,深达深筋膜深层,原位缝合,2周后常规切取皮瓣转移至患处,观察皮瓣成活情况及创面愈合效果。结果5例患者皮瓣全部成活;随访3个月~1年,5例患者的皮肤质地及外形均恢复较好。结论采用超长腓肠神经营养血管皮瓣延迟转移修复小腿上端及足踝部软组织缺损,增加了皮瓣长度,扩大了皮瓣修复范围,且切取简便,供血可靠,效果良好。     

逆行第一趾背皮神经营养血管皮瓣修复足趾端皮肤缺损及骨外露

目的:探讨逆行第一趾背皮神经营养血管皮瓣修复足第一趾远端软组织缺损及骨外露的治疗方法。方法:一期或二期应用逆行第一趾背皮神经营养血管皮瓣修复足第一趾远端软组织缺损及骨外露,切取皮瓣最大面积为4.0cm×3.0cm,临床应用6例。结果:除1例发生边缘坏死外,其余全部成活,术后随访5个月～25个月,皮瓣质地满意,患足功能稳定。结论:使用逆行第一趾背皮神经营养血管皮瓣修复足远端软组织缺损及骨外露,手术简便,疗程短,效果满意。     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.