COMPARATIVE OBSERVATION ON EFFECT OF ELECTRIC ACUPUNCTURE OF NEIGUAN (P 6) AT CHEN TIME VERSUS XU TIME ON LEFT VENTRICULAR FUNCTION IN PATIENTS WITH CORONARY HEART DISEASE

Paired experimental design was adopted in this experiment for comparative observation on effect of electric acupuncture (EA) of Neiguan (P 6) at Chen Time (7 a.m. to 9 a.m.) versus Xu Time (7 p.m. to 9 a.m.) on left ventricular function in patients with coronary heart dis-ease (CHD). The results show that EA performed at Chen Time could improve the left ventricular function of CHD patients as indicated by shortening of PEPI and decrease of PEPI/LVETI ratio; on the contrary, EA performed at Xu Time prolonged PEPI and raised PEPI/LVETI ratio in CHD patients, suggesting impairment of left ventricular function.     

PRELIMINARY INVESTIGATION ON THE EFFECT OF ACUPUNCTURE OF NEIGUAN(P.6)AND SHAOFU(H.8)ON CARDIAC FUNCTION OF IDIOPATHIC CARDIOMYOPATHY

An investigation on acupuncture of Neiguanand Shaofu was carried out in 12 normal indi-viduals(N),24 cases of hypertrophic obstructivecardiomyopathy(HOCM)and 16 cases of con-gestive cardiomyopathy(CCM).Acupuncture ofthe point was performed over both arms.Afterthe patient felt the needling sensation,a directcurrent of 120 times/minute frequency was con-nected to the needles for 2 minutes,after whichthe needles were retained in place for 15 minutes.Echocardiogram,apex cardiogram,and systolictime interval(STI)were recorded before andafter the acupuncture.Pulmonary capillaryweuge pressure(PCWP)was measured in 2patients.After puncturing Neiguan there was 1)aslight increase of left ventricular outflow tract(LVOT)diameter in N,a significant decrease inHOCM and a significant increase in CCM;2)stroke volume(SV)and cardiac output(CO)were increased in N and CCM,decreased inHOCM;3)the Dd and Ds(internal diameter ofleft ventricle during diastole and during systole)were slightly decreased in N and CCM,increasedin HOCM;4)the LVPWs and LVPWd wereslightly increased in N,HOCM and CCM;5)theSTI was slightly shortened in N and CCM,notchanged in HOCM;6)the PCWP was decreasedin CCM,increased in HOCM.Acupuncture of Shaofu resulted in no changeof LVOT diameter in N,a slight increase inCCM,and a marked increase in HOCM.SV andCO were decreased slightly in N and markedlydecreased in CCM;they were markedly increas-ed in HOCM.The LVPWd and LVPWs weredecreased in N,CCM and HOCM.There was aslight prolongation of STI in N,HOCM andCCM. The authors concluded that acupuncture ofNeiguan could increase cardiac contraction andbe beneficial in heart failure due to CCM orother causes,but could worsen cardiac functionin HOCM.Acupuncture of Shaofu could decreasecardiac contraction and benefit patients withHOCM,but harm heart failure patients withCCM.     

Journal of Medical Science Yanbian University(2005 Vol.28) INDEX OF SUBJECTS

Aacids 187administration,topical 77alcohol,ethyl 259aminophenols 183aminotransferases 31anastomosis,surgical 121anesthesia 207angina,unstable 131angiography 124ankle injuries 133anoxia 26,110,253,257anthraquinones 116anticonvulsants 38antisepsis 36apoptosis 1assaying 266astragalus 87astrocytoma 286autopsy 278Bbeverages 102biological activity 161biopsy 53bladder 64blepharoptosis 287blood glucose 268bloodloss,surgical 143blood pressure 45,190,268blood vessels 121bone defect 13bone screws 59bone t…     

SURGICAL TREATMENT OF INTRACRANICAL ANEURYSMS (A REPORT OF 55 CASES)

<正> Fifty-five patients with intracranial cerebral aneurysmswere directly operated on. Surgical management of this disease, characteristics of intracranial aneurysms, and technical key points in treatment of aneurysms are discussed.     

INDEX OF SUBJECTS Journal of Medical Science Yanbian University(2003 Vol.26)

Aabortion ,habitual　 46abortion ,induced　 44acquiredimmunodeficiencysyndrome　10 8acuteperiod　 63administration ,inhalation　 48adult　 13 3agefactors　 63 ,183aged　 2 85aging　 18alcoholdrinking　 199alopecia　 2 95amoeba　 168analgesia　 48anatomy　 2 3anesthesia　 41anesthesia ,general　 3 9angiography　 189angiotensins　 79anoxia　 2 97anti arrhythmiaagents　 2 66antibodies ,monoclonal　 86antibodyspecificity　 86antidotes　 2 48antilipemicagents　 2 51arrhythmia　 2 66arteries　 79asph…     

INFLUENCE OF “SHUGANJIEYU” (舒肝解郁) HERBS ON CHOLERETIC FUNCTION IN ANESTHETIZED RATS

Experimental results of the choleretic ef-fect and influence on bile constituents of“Shuganjieyu (舒肝解郁)” herbs are reported.The evidence was that of the nine individuallytested herbs given 10 gm/kg via the duodenum,Lignum Aquilariae Resinatum,PericarpiumCitri Reticulatae Viride,Rhizoma Cyperi andPericarpium Citri Reticulatae markedly in-creased hepatic bile flow,for 3-4 hrs or longer.Radix Bupleuri,Fructus Aurantii and RadixCurcumae were also choleretic,though thesewere not so dramatically so.Compared withthe control,Fructus Aurantii and PericarpiumCitri Reticulatae Viride markedly and correspon-dingly elevated the cholic acid content and solidscomponent of bile.Bilirubin excretion increasedafter administration of Radix Aucklandiae.Two hrs after administering Fructus MeliaeToosendan the biliary lecithin level dropped toless than the control,though the drop was notstatistically significant.It is possible that“Shuganjieyu” exerts therapeutic action partlythrough choleresis,and that the so-calledGanyu (肝郁)symptoms mentioned in ancientChinese medical literature represent thepathologic processes of biliary excretion distur-bance.The pharmacological actions of “Shugan-jieyu” herbs as discussed may make the herbsbeneficial in enhancing liver function,prevent-ing cholesterol stone formation,diminishing in-trahepatic cholestatic jaundice risk,promotingabsorption of fat-soluble substances in the gut,and preventing steatorrhea.     

INDEX FOR THE,STANDARD NOMENCLATURE OF ZHENJIU(ACUPUNCTURE AND MOXIBUSTION)POINTS IN ALPHABETIC ORDER

The Chinese pinyin(phonetic alphabet)as formulated and widely used is very important inChinese cultural life.The phonetic system provides a more universal means for spelling names ofpersons,places,books and scientific terms.It is especially valuable in the making of indices.Chinese pinyin for point names in acupuncture has been used for more than 25 years,the first ac-upuncture text using the system for point names having been published in China early in 1959.Further,in the past decade and more,the pinyin has been used for Chinese point names in cer-tain acupuncture textbooks and journals in other countries,among them Austria,Canada,England,France,West Germany,India,Italy and Sri Lanka.Now,Chinese pinyin for point names hasbeen standardized on an international scale.     

β-FIBRINOGEN PROMOTER -455 G/A(HaeIII)POLYMORPHISM PREDICTION OF PLASMA FIBRINOGEN BUT NOT OF ISCHEMIC CEREBROVASCULAR DISEASE

ANelevatedplasmafibrinogenlevelisariskfactorforcardiovasculardiseaseincidenceandmortality.12β-fi-brinogengenepolymorphismsinfluenceplasmafibr-Ainogenlevels.3SurveysgenerallybutnotuniformlyindicatedadultswiththeAalleleforthe-455G/ApolymorphismHaeⅢhaveincreasedfibrinogenlevels.4-7Somestudiesobservedassociationof-455Aallelewithelevatedplasmafibrinogenwaspredomin-antinsmokers89butotherstudiesalsofoundthisas-sociationtoonlybeobservedincurrentnonsmokers.10TheassociationbetweenpresenceoftheAalle…     

β-FIBRINOGEN PROMOTER-455 G/A (HaeⅢ) POLYMORPHISM PREDICTION OF PLASMA FIBRINOGEN BUT NOT OF ISCHEMIC CEREBROVASCULAR DISEASE

Objective The-455 G/A (HaeⅢ) polymorphism of β-fibrinogen gene influences levels of plasma fibrinogen. We further investigated whether it influences the risk of ischemic cerebrovascular disease. Methods We accumulated 134 acute ischemic cerebrovascular disease (ICVD) cases and compared their -455 G/A status with a control group (n = 166). The β-fibrinogen gene -455 G/A polymorphism was analyzed for all subjects by PCR-RFLP with the restrictive enzyme HaeⅢ. Results Plasma fibrinogen was higher in AA homozygous participants (341 mg/dL) than in participants carrying the G allele: GA (290 mg/dL), GG (298 mg/dL) in the control group. Plasma fibrinogen was also higher in AA homozygous patients (353 mg/dL) than in cases carrying the G allele: GA (287mg/dL), GG (302 mg/dL) in the ICVD group. However, there was no significant association between β-fibrinogen gene -455 G/A polymorphism and ICVD group. Conclusions Although a small effect cannot be excluded, β-fibrinogen gene -455 G/A polymorphism is an independent predictor of plasma fibrinogen, but not of ischemic cerebrovascular disease.     

XIAO Pei-Gen(肖培根)──A World Wide Famous Ethnopharmacologist

ＸＩＡＯ　Ｐｅｉ－Ｇｅｎ（肖培根）──Ａ　Ｗｏｒｌｄ　Ｗｉｄｅ　Ｆａｍｏｕｓ　ＥｔｈｎｏｐｈａｒｍａｃｏｌｏｇｉｓｔＰｒｏｆｅｓｓｏｒＸＩＡＯＰｅｉ－ｇｅｎｉｓｔｈｅｆｏｕｎｄｅｒａｎｄｒｅｓｅａｒｃｈｌｅａｄｅｒｏｎＣｈｉｎｅｓｅｍｅｄｉｃｉｎａｌ...     

IMMUNOSUPPRESSIVE TREATMENT OF CHILDHOOD APLASTIC ANEMIA WITH ANTITHYMOCYTE GLOBULIN (ATG) AND CYCLOSPORIN A (CSA)

This paper described the therapeutic efficacy of immunosuppressive (IS) treatment agents (ATG and CSA) and androgens in the treatment of childhood aplastic anemia (AA). The results showed that the overall curative rate was 52.4% in the ATG therapy group (21 cases) and 58.3% in the CSA therapy group (12 cases) respectively. The effective rate of all patients (SAA and CAA) was 58.1% in the IS group (18/31) and 40.4% in the androgens group (42/104), P>0.05. But, in the childhood patients with SAA, the clinical effective rate was 68.4% in the IS group and 7.9% in the androgens group, P<0.01. The laboratory tests revealed that the majority of the AA patients displalyed abnormal immunological states: inversed CD4/ CD8 ratio and increased IL-2 activity. These abnormal immunological states could be normalized in several patients when clinical response was abtained following IS therapy with ATG and CSA.     

PBLT AND THE CONCERNED PROBLEMS (WITH A REPORT OF 48 CASES)

1　Ｐａｔｉｅｎｔｓａｎｄｍｅｔｈｏｄｓ1.1　ＣｌｉｎｉｃａｌｄａｔａＦｏｒｔｙ -ｅｉｇｈｔｃａｓｅｓｏｆｅｎｄ -ｓｔａｇｅｌｉｖｅｒｄｉｓｅａｓｅｓｗｅｒｅｈｏｓｐｉｔａｌｉｚｅｄｆｒｏｍＳｅｐｔｅｍｂｅｒ ,1995ｔｏＤｅｃｅｍ ｂｅｒ ,2 0 0 0ｉｎｏｕｒｈｏｓｐｉｔａｌ,ｗｉｔｈａｇｅｓｆｒｏｍ 9- 6 2 ｙｅａｒｓｏｌｄ ,ｉｎｃｌｕｄｉｎｇ 4 3ｍａｌｅｓａｎｄ 2ｆｅｍａｌｅｓ ,3ａｍｏｎｇｗｈｉｃｈｈａｄｌｉｖｅｒｒｅｔｒａｎｓｐｌａｎｔａｔｉｏｎ .Ｔａｂ .1　ＩｎｄｉｃａｔｉｏｎｏｆｔｈｅＰＢＬＴＷ…     

DETECTION OF LEUKEMIA INHIBITORY FACTOR (LIF) BY A ENZYME-LINKED IMMUNOSORBENT ASSAY

LIF is a cytokine with leiotropic activities. In order to understand better the physiological and patho-physiological role of LIF. we have developed a simple and specific enzyme-linked immunosorbent assay (ELISAI for detecting LIF in human plasma and serum and in tissue culture media. A monoclonal ami-LIF antibody 8B11 (IgGl) produced in our laboratory was coated onto microtiter plates. After block-     

AURICULOACUPUNCTURE THERAPY——A TRADITIONAL CHINESE METHOD OF TREATMENT(Continued)

CHRONIC CONSTIPATIONTREATED WITHAURICULOACUPUNCTUREChronic constipation is caused mainlyby irregular toilet habits or sluggishintestinal peristalsis,resulting in prolongedretention of feces which become dehydratedand hard and not excreted for days.Some-times the feces may not be very dry,but thedefecation muscles are too weak for the     

ANEURYSM OF SINUS OF VALSALVA DISSECTING INTO THE INTERVENTRICULAR SEPTUM – ECHOCARDIOGRAPHIC DIAGNOSIS (A Case Report)

Aneurysm of sinus of Valsalva dissecting into interventricular septum is a rare entity. We report one such case who was incidentally diagnosed by echocardiography to have this abnormality during evaluation of a clinically suspected isolated aortic regurgitation.KEY WORDS: Aneurysm – dissecting – sinus of Valsalva, Echocardiography     

THE BENEFICIAL EFFECTS OF CYCLOVIROBUXINE D(CVED)IN CORONARY HEART DISEASE A DOUBLE BUND ANALYSIS OF 110 CASES

Cyclovirobuxine D is an alkaloid extractedfrom Buxus microphylla Sieb.et Zucc.var sini-ca Rehd.et Wils.in Chinese the herb Huang-yang.In 1981,198 cases of coronary heart disease(CHD)were treated with this drug with satis-factory results.In 1982,another 110 cases of CHD treatedwith Cyclovirobuxine D or placebo were studi-ed using the randomized double blind method.The results were as follows:The effectiveness rate of cyclovirobuxineD for angina pectoris was 80.9%(P<0.05),ECGimprovement 65.5%(P<9.01)and cardiac func-tion improvement 57.4%(P<0.01),while withplacebo these percentages were 59.6,25.9 and20.8 respectively.There was significant dif-ference between the treated and the placebogroups.After cyclovirobuxine D treatment thestroke volume increased markedly from 66.90to 75.59 ml/beat,PEP/LVET and SFW/RFW andN-S_2/C-S_2,ratios decreased while cardiac indexshowed no obvious change.These indices werethe same in the placebo group except for theincreased SFW/RFW ratio.This shows thatcyelovirobuxine D is effective in treating CHDpatients.     

A New Drug Delivery System──Ciprofloxacine/TricalciumPhosphate Delivery Capsule (CTDC) and Its In Vitro DrugRelease Pattern

Drugdeliverysystem(DDS)isanewmethodofmedicationdevelopedinrecenttwodecadeswiththeavailabilityofmanynewbiomaterialsthathavegoodbiocompatibility,fromwhichdrugcanbedelivereddirectlytothedesiredsitesustainedlyatmuchhigherconcentrationsthancanbeachievedbyconventionalroutes.AmplescientificevidencesintheuseofDDS,suchasantibioticimpregnatedpolymethylmethacrylate(PMMA),antibioticloadedporoushydroxyapatite(PHA)andantibioticloadedpolyglycolicacid/polylacticacid(PGA/PLA)copolymerforthetreatmentofmy…