前纵隔病变的CT引导经皮切割针穿刺--非经胸骨的活检

目的：探讨非经胸骨的前纵隔病灶切割针穿刺的方法、技术、临床价值及其并发症。资料与方法：回顾性分析1992－2001年间共对39例前纵隔病变行CT引导下的非经胸骨的经皮穿刺。所用穿刺针为16、18、19和20G自动芯状活检枪。所有病例同时行细胞学和组织学检查，并分析其准确性和并发症。结果：35例得到病理诊断。包括淋巴瘤6例，转移性肿瘤5例（腺癌2例，鳞癌2例，低分化癌1例），恶性肿瘤（未能分型）5例，胸腺瘤4例，腺癌、鳞癌、胸内甲状腺、结核、结节病各2例，恶性畸胎瘤、内胚窦瘤、小圆细胞瘤、Castleman‘s病、纵隔血肿各1例。失败4例，原因为切割组织太少（2例），肿瘤液化坏死（1例）和抽吸物为血液（1例）。随后确诊为淋巴瘤3例，另1例颈部活检为转移性低分化癌，系假阴性。并发症包括皮下血肿3例，纵隔血肿2例，纵隔气肿2例。准确率为89．7％（35／39），假阴性率为10．3％（4／39），总的并发症发生率为17．9％（7／39）。结论：CT引导下非经胸骨的经皮前纵隔穿刺适用于前纵隔各个部位的病灶，是一种较经胸骨活检更简便和安全的定性诊断方法。     

CT引导下经皮穿刺活检诊断胸部疾病的临床应用价值

目的:探讨CT引导下经皮穿刺活检诊断胸部病变的临床应用价值。材料和方法:用Chiba穿刺针在CT引导下对52例胸部病变进行穿刺活检。结果:52例均穿刺成功,出现气胸5例,局部出血和咯血2例,胸部并发症发生率13.5%,诊断准确率88.5%。结论:CT引导下经皮穿刺活检对胸部病变的诊断准确性高,并发症较少,具有重要临床应用价值。     

CT引导下经皮穿刺活检诊断颈部病变

目的 评价CT引导下的颈部病灶经皮穿刺活检的临床应用价值.方法 在CT引导下对15例颈部病灶经皮穿刺活检.结果 CT证实15例穿刺活检针均在病灶内,穿刺成功,全部取得病理结果,其中13例与临床诊断相一致.结论 CT引导下经皮穿刺活检颈部病变是安全、准确、微创的介入诊断技术.     

CT导引下的纵隔病变穿刺活检

目的探讨CT导引纵隔病变穿刺活检技术及其临床意义。方法35例纵隔病变在CT导引下行穿刺活检。结果35例纵隔病变穿刺活检病灶成功率100%。诊断准确率94.2%(33/35),其中恶性病变诊断准确率100%(21/21),良性病变为85.7%(11/14)。并发气胸3例(8.6%),纵隔出血1例(2.9%)。结论CT导引下穿刺活检术对于纵隔病变诊断的正确率高,对纵隔病变的诊治具有很大的帮助。     

CT引导下经皮椎体病变穿刺活检的临床研究

目的评价CT引导下经皮椎体病变穿刺活检的成功率、诊断正确性及临床应用价值。方法85例椎体病变患者经皮穿刺活检,病变位于颈椎3例,胸椎26例,腰椎37例和骶椎19例。影像学上表现57例为溶骨性病变,19例成骨性病变,9例溶骨性与成骨性病变共存。穿刺标本行细胞学及组织学检查。临床怀疑感染性病变时行细菌学检查。对穿刺标本进行诊断的正确性分析。结果CT证实85例穿刺活检针均位于病灶内,81例取得病变组织,活检成功率95%。活检标本包括29例骨组织标本,5例软组织标本,47例骨组织与软组织混合标本,4例未取得标本;病理结果包括44例转移瘤,17例原发性骨肿瘤,18例感染性病变,2例正常椎体组织。79例诊断正确,诊断正确性97.5%。结论CT引导下经皮椎体病变穿刺活检是对椎体病变作出正确诊断的重要手段,为临床提供了可靠的组织学依据,且穿刺部位正确、三维定向好、损伤小,可以作为诊断不明确的溶骨性及溶骨与成骨混合性椎体病变拟行椎体成形术术前常规。     

CT引导下肠道占位病变穿刺活检的临床应用北大核心CSCD

目的 探讨CT引导下经皮穿刺活检对肠道占位病变肠镜活检的补充诊断价值。方法 回顾性分析2015年1月至2021年5月陆军军医大学第一附属医院行CT引导下穿刺活检的35例患者的临床资料。收集患者基本信息,病灶所在位置,比较经皮穿刺活检与肠镜活检的取材成功率、诊断准确率、以及并发症的发生情况。结果 35例患者共有36处病灶,病灶位于十二指肠1处,空肠1处,回盲部3处,结肠16处,直肠15处。CT引导下经皮穿刺活检取材成功率为100%(36/36),肠镜活检成功率为55.6%(20/36),差异有统计学意义(P<0.05);CT引导穿刺活检诊断准确率为95%(19/20),肠镜活检准确率为50%(10/20),差异有统计学意义(P<0.05)。CT引导穿刺术后随访未见明显穿刺相关并发症。结论 CT引导下肠道占位病变经皮穿刺活检是一种安全、可行、有效的方法,可作为肠道占位病变标本活检的补充手段。     

CT引导下经皮经胃胰头占位病灶的活检

目的 探讨CT引导下经皮经胃胰头占位病灶穿刺活检术的方法和诊断意义.方法 对我院收治的10例胰头占位患者,在CT引导下行经皮经胃胰头占位穿刺活检术,对病例资料进行回顾性分析.结果 均穿刺成功,取得满意的病理组织.10例中,病理检查结果提示8例为胰腺癌,2例为硬化性胰腺炎,对后期治疗提供了极大的帮助.其中8例出现穿刺点疼痛,3例出现术后血淀粉酶升高,1例发生胰腺穿刺点出血约200 ml,经过止痛、生长抑素抑制胰腺分泌、止血后好转.无胃瘘、肠瘘、胰漏、胃出血、针道转移等发生.结论 CT引导下经皮经胃胰头占位活检术是一种安全、可行的诊断方法.     

CT引导下经皮肺穿刺活检对周围型肺部病变的诊断价值

目的探讨CT引导下经皮肺穿刺活检对周围型肺部病变的诊断价值及其安全性。方法对58例周围型肺部病变的患者,在CT引导下行经皮肺穿刺活检。结果 58例患者中穿刺标本经组织病理学检查确诊病例48例,确诊率为82.8%,其中恶性肿瘤32例,良性病变16例。术后出现有症状并发症7例,其中咯血2例,气胸4例,高热伴脓胸1例,总发生率为12.1%。结论 CT引导下经皮肺穿刺活检定位准确,成功率高,安全可靠,在周围型肺部病变诊断中具有较高的应用价值。     

CT引导下经皮肺穿刺活检经验总结

目的：探讨CT导引下经皮肺穿刺活检的技术方法和影响诊断准确性的因素，防范并发症的心得。方法：回顾性分析36例肺内病变CT引导下经皮肺穿刺活检的技术方法，就如何提高穿刺准确性及影响诊断准确率的因素、防范并发症的心得进行讨论。结果：36例中，穿刺成功率100％，活检诊断准确率为30／36（83％）。3例发生轻度气胸。结论：CT引导下经皮肺穿刺活检术是安全的，可有效提高肺内病变的诊断准确性。但操作医生熟练的技术方法非常重要，并可以减少并发症的发生。     

激光倾角仪在CT引导下经皮纵隔穿刺活检中的应用北大核心CSCD

目的探讨激光倾角仪引导进针角度装置在CT引导下经皮纵隔穿刺活检中的应用价值。方法选择2017年4月至2022年4月湖北省肿瘤医院放射科CT引导下经皮纵隔穿刺活检患者100例,其中采用激光倾角仪引导下穿刺患者50例,采用常规穿刺患者50例。对比两组一次穿刺靶灶成功率、CT扫描次数、进针时间及穿刺并发症、穿刺病理阳性率。结果激光倾角仪组一次穿刺达靶灶率为74%(37/50),常规穿刺组为42%(21/50),差异有统计学意义(χ^(2)=10.509,P=0.01)。激光倾角仪组CT扫描次数为(3.42±2.05)次,常规穿刺组为(5.42±3.37)次,差异有统计学意义(t=8.502,P=0.004)。激光倾角仪组进针时间为(8.67±3.12)s,常规穿刺组为(12.08±4.70)s,差异有统计学意义(t=10.120,P=0.002)。激光倾角仪组出现并发症12例(24%),常规穿刺组出现并发症22例(44%),差异有统计学意义(χ^(2)=4.456,P=0.035)。激光倾角仪组病理阳性率为94%(47/50),常规穿刺组为92%(46/50),差异无统计学意义(χ^(2)=0.154,P=0.695)。结论激光倾角仪引导进针角度装置联合CT引导下经皮纵隔穿刺活检术可使穿刺更加精准和安全,值得临床推广应用。     

CT-guided biopsy of pelvic masses

CT-guided fine-needle puncture (FNP) was carried out in 74 patients with pelvic masses and resulted in a correct diagnosis in 36/45 patients (80%) with malignant disease. FNP was true-positive in 66.7% and false-negative in 20%. In benign and inflammatory pelvic space-occupying lesions, FNP confirmed the suspected CT diagnosis in all cases by cytology and bacteriology. CT-guided puncture should always be used complementary to CT when a mass of unclear etiology is present.     

CT引导经皮肺穿刺活检术对肺门肿块的诊断价值

目的 研究CT引导经皮肺穿刺活检术对肺门肿块的诊断价值.方法 76例纤维支气管镜检查失败或没有明确病理结果的肺门肿块患者行CT引导经皮肺穿刺活检术.结果活检阳性率为100％.结果 获鳞癌32例,小细胞癌13例,腺癌27例,大细胞癌3例,淋巴瘤1例.其中58例行EGFR突变位点检测,突变率为46.6％(27/58).结论 CT引导经皮肺穿刺活检术对肺门肿块诊断阳性率高,可提供可靠的病理诊断指导临床治疗.     

CT-guided transthoracic needle biopsy

CT-guided biopsy of pulmonary and mediastinal lesions is safe and effective. It is most valuable in those cases in which fluoroscopic guidance is not possible due to resolution or anatomic consideration. CT guidance permits puncture of lesions as small as 0.5 cm, typically not seen fluoroscopically. Sensitivity of biopsy in malignant lung lesions in our series of 83 cases was 92%. Pneumothorax is the most frequent complication (10–60%) and requires chest tube insertion in 5–15% of patients.     

CT-guided core-needle biopsy in the diagnosis of mediastinal lymphoma

The advent of radiologic guidance techniques for percutaneous biopsy has changed the approach to the routine diagnosis of mediastinal lymphoma. The aim of the present study was to evaluate the diagnostic accuracy of CT-guided percutaneous core-needle biopsy (PCNB) in the clinical management of patients with mediastinal lymphoma. The results of 49 CT-guided PCNB of mediastinal lymphoma performed under local anesthesia in 42 ambulatory patients were analyzed. A positive diagnosis of lymphoma was obtained in 30 of 42 patients, with an overall success rate of 71.5 %. The technique was equally successful in the diagnosis of Hodgkin's and non-Hodgkin's lymphoma. There were no major complications. Percutaneous CT-guided CNB of mediastinal lymphoma is a quick, safe, accurate, and efficient alternative to open biopsy in the evaluation of mediastinal lymphoma, mainly at presentation. It should become the preferred initial diagnostic procedure for obtaining histologic samples in patients with suspected mediastinal lymphoma. Received: 28 January 1999; Revised: 21 May 1999; Accepted: 15 October 1999     

CT-guided percutaneous transthoracic biopsy in the diagnosis of mediastinal masses: evaluation of 73 procedures

PURPOSE: This study was performed to evaluate the factors affecting the diagnostic accuracy and rate of complications of CT-guided percutaneous transthoracic needle biopsy of mediastinal masses. MATERIALS AND METHODS: We reviewed 73 consecutive mediastinal biopsies in 70 patients. Final diagnoses were based on a retrospective analysis of surgical outcomes, results of repeat biopsies or findings of imaging and clinical follow-up lasting at least 4 months. Benign and malignant biopsy findings were compared with the final outcomes to determine the diagnostic accuracy of the method. Finally, we analysed the complications. RESULTS: CT-guided percutaneous transthoracic needle biopsy provided adequate samples in 61/73 cases, with a total sample rate of 83.6%. Of these 61 biopsies, 51 yielded a correct diagnosis with specific histological typing, mainly in the case of thymoma and metastasis. Lymphomas were less reliably diagnosed. The overall sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy values were 83.6%, 100%, 100%, 35.3% and 83.6%, respectively. Pneumothorax was the most common complication (5.5%). CONCLUSIONS: CT-guided percutaneous transthoracic needle biopsy is an easy, reliable and safe procedure that obviates the need for exploratory surgery in medically treatable or unresectable cases. It should be the first invasive procedure in the diagnostic workup of mediastinal masses.     

超声引导周围型肺病变穿刺活检的临床应用

目的:探讨超声引导下周围型肺病变穿刺活检技术及临床应用价值。方法:选用16～18G切割式半自动穿刺活检针,在超声引导下对35例需明确诊断的周围型肺病变患者行超声引导下经皮穿刺活检术。结果:35例患者均穿刺成功,成功率100%;34例确诊,活检确诊率97.1%。结论:超声引导下周围型肺病变穿刺活检具有定位准确、操作简便、安全性好、并发症少及重复性强等优点,为疑难性周围型肺病变明确诊断的首选方法。     

骨骼破坏性病变CT引导下经皮穿刺活检方法比较与应用

目的比较骨骼破坏性病变在CT导引下经皮穿刺不同活检方法的临床应用。方法经X线和MR发现的89例骨骼破坏性病变,在CT导引下采用不同的穿刺方法：①穿刺负压抽吸法;②18～20G半自动活检切割针取样法;③11～13G骨钻 半自动活检切割取样法。对组织样本分别进行常规病理和免疫组织化学检查。结果75例获得完整病理学标本或培养出结核杆菌,穿刺准确率84．3％(75／89),假阴性率15．7％(14／89),未出现假阳性。骨钻 活检切割法准确率高于其他方法,3种穿刺方法准确率无显著性差异。结论①CT导引穿刺活检对骨骼破坏性病变诊断有很大帮助;②根据病灶类型合理选择穿刺方法可提高准确率。     

Diagnostic value of CT-guided biopsy of indeterminate renal masses

AIM: To evaluate the role of percutaneous core biopsies in the diagnosis of renal masses that could not be classified as benign or malignant based upon imaging alone. MATERIALS AND METHODS: We retrospectively analysed core biopsies of indeterminate renal masses of 23 patients who were referred to us for computed tomography (CT)-guided biopsy from 1996-2001. Follow-up ranged from 1-5 years. Analysis was based on indications for biopsy, size and characteristics of the lesion and accuracy of biopsy results. RESULTS: There was one technical failure in 22 patients included in the analysis. Fifteen core biopsies revealed malignancies that were confirmed either clinically or surgically. Seven were benign, one of which was false-negative. The sensitivity was 93%, specificity 100%, positive predictive value 100% and negative predictive value 75%. The results in tumours <==3 cm were similar to those in larger lesions. CONCLUSIONS: We recommend the use of core biopsy as a diagnostic tool for indeterminate renal masses, regardless of mass size. Renal core biopsy can influence the management of lesions: primary renal lesions are resected, while treatment for metastatic disease is tailored to the primary tumour. Tumours with benign biopsy results should be re-evaluated and either referred for resection of the mass or followed up closely with clinical observation and of imaging studies.     

CT导向经皮穿刺椎体活检术在椎体病变中的诊断价值

目的探讨CT导向下经皮穿刺椎体活检技术及其对椎体病变定性诊断的价值。资料与方法62例椎体病变患者,男45例,女17例,单椎体病变38例,两椎体病变14例,多椎体病变10例。其中颈椎2例,胸椎28例,腰椎25例,骶尾椎7例。颈椎病变患者取仰卧位,胸、腰、骶椎病变患者取俯卧位。在CT横断扫描导向下,对病变部位穿刺活检,穿刺标本送病理学检查。结果62例患者均穿刺成功,52例(80.8%)成功取得病理组织并得到明确的病理结果,6例未取得病理组织,3例病理诊断不明确,1例不相符。行免疫组织化学检查10例,得到了明确的组织学诊断,4例恶性病变因细胞组织太少仍不能明确组织学特征。结论CT引导下椎体穿刺活检术,具有微创、安全、取材准确、可靠、方便等优点,是脊柱病变活检的理想方法,可以为临床提供可靠的组织学依据。