共查询到20条相似文献,搜索用时 31 毫秒
1.
ObjectiveToinvestigatethemechanismofcytokineregulationinatopybyanalyzingtheefectsofthreemajorcytokines,IL4,IL12andIFNγonin... 相似文献
2.
Inhibition of mesangial cell proliferation by antisense oligodeoxynucleotide targeting preproendothelin-1 mRNA in vitro 总被引:2,自引:0,他引:2
Objective Toinvestigatetheeffectsofendothelin1(ET1)onmesangialcellproliferationinvitroMethods Antisenseoligodeoxynucleotide(AsODN)anditscontrolsequences,sense(SeODN)andmismatch(MisODN)oligodeoxynucleotides,targetingpreproendothelin1(ppET1)mRN… 相似文献
3.
白细胞介素2(IL2)的作用有赖于与IL2受体(IL2R)的相互作用,细胞膜结合的IL2R,可释放到血液中成为可溶性形式(sIL2R),现将42例急性白血病sIL2R检测结果报告如下。材料与方法1观察对象本组42例,男性29例,女性13... 相似文献
4.
ObjectiveTostudythescheduledependentreversionofcisdiamminedichloroplatinum(CDDP)resistanceby5fluorouracil(5Fu)inaCDDPresi... 相似文献
5.
Effect of WT1 gene expression on cell growth and proliferation in myeloid leukemia cell lines 总被引:1,自引:0,他引:1
Wilms’tumor(WT1)geneisatumorsupressorgeneidentifiedinWilms’tumorpatientsItislocatedonchromosome11p131 ThelengthofWT1geneisabout50KbThereare2splicingexonsoutofits10exons:exon5(spliceⅠ)andexon9(spliceⅡ)Thepresenceoftwoalternativesplicesresultsinfo… 相似文献
6.
目的:探讨几种肝病患者外周血可溶性白细胞介素2受体(sIL2R)水平状态及其临床意义。方法:采用双抗体夹心ELISA法检测慢性乙型肝炎、肝硬化和原发性肝癌患者(共70例)与健康人(22例)的外周血sIL2R水平,并比较原发性肝癌(15例)手术前后sIL2R水平的变化。结果:与对照组相比,慢性乙型肝炎、肝硬化和原发性肝癌患者的sIL2R水平明显增高;肝癌术后sIL2R水平明显下降;sIL2R水平与肝癌临床分期相关。结论:进一步证实血清sIL2R水平可间接反映几种肝病的细胞免疫功能状态。 相似文献
7.
InChina,manytraditionalherbalremedieshaveshowneffectivenessintreatingsuperficialburns1 Onemechanismbywhichtheseagentsworkhasbeensuggestedtobetheirantiinflammatoryandimmunomodulatoryeffects2 BurnHealingLiquid(BHL)isoneoftheseherbalmixturesItisanaq… 相似文献
8.
TheC→TsubstitutionatthepositionofIVS2nt.654(IVS2654C→T,β654),amutationcausingdefectinRNAsplicing,isoneofthemostcommonβtha... 相似文献
9.
Epstein-Barr virus infection in nasopharyngeal lymphoid hyperplasia 总被引:10,自引:0,他引:10
Objective TodetectwhetherEpsteinBarrvirus(EBV)harborsinnasopharyngeallymphoidhyperplasia(NPLH)whichisfrequentlytobeseeninGuangzhou,ahighincidenceareaofnasopharyngealcarcinoma(NPC),andtoexploretherelationbetweenNPLHanddevelopmentofNPCMethods Twenty… 相似文献
10.
ObjectiveTofurtherinvestigatetheefectsofultraviolet(UV)iradiatedurocanicacid(UCA)onTlymphocytes,theefectsofcisUCAonTlymphoc... 相似文献
11.
Relationship between angiotensinogen gene M235T variant with diabetic nephropathy in Chinese NIDDM 总被引:4,自引:0,他引:4
Objective Toinvestigatewhetherangiotensinogen(AGT)geneM235Tvariantisassociatedwithnoninsulindependentdiabetesmellituswithoutnephropathy(DN-),anddiabeticnephropathy(DN+)inChinesenoninsulindependentdiabetesmellitus(NIDDM)Methods ThesubjectsinDN+gr… 相似文献
12.
为观察香菇多糖脂质体(LiposomescontainingLentinan,LipLNT)与低剂量IL2协同体内扩增,激活腹腔巨噬细胞(Peritonealmacrophage,PM)杀瘤活性。体内诱导Balb/c小鼠2d后,收集计数腹腔渗出细胞(Peritonealexudatecels,PEC)及PM,监测PM细胞毒及TNF活性,并于香菇多糖(Lentian,LNT)进行了比较。结果:LipLNT,LNT与IL2联合可协同使PEC体内大量扩增,PM细胞毒活性及TNF分泌显著增加,其中LipLNT较LNT最小有效剂量减小5倍,最适剂量减少4倍,而PM杀瘤活性提高30%,且以靶向扩增PM为主,达72%。结论:LipLNT较LNT生物活性显著提高,LipLNT与小剂量IL2联合使PM、PEC体内大量增殖,PM杀瘤活性增强并促进TNF生成。 相似文献
13.
Objective Toinvestigatethefeasibilityofourselfmadeinferiorvenacave(IVC)stentMethods Selfexpanding,stainlesssteel,ZshapedstentsweredeployedintheIVCof14dogsTheywererandomlydividedintofourgroups,fourdogsinthefirstthreegroups,and2inthefourthgroup.IVC… 相似文献
14.
Objective Tostudytheinteractionbetweenoncogenemdm2andwp53inhumanglandularlungcancercelllineGLC82.MethodsBylipofectaminemediatedDNAtransfection,wp53andmdm2weretransfectedseparatelyorcotransfectedintoGLC82cellsviaretrovivalvectorpDORneo,acarriero… 相似文献
15.
肺癌患者围手术期血清sIL-2R的检测 总被引:1,自引:0,他引:1
应用ELISA双抗夹心法检测了30例正常健康人及40例肺癌患者围手术期血清sIL2R的水平。结果显示:肺癌组术前血清sIL2R水平显著高于正常对照组(P<001);手术切除后血清sIL2R水平明显下降(P<005);肺癌细胞分型与血清sIL2R水平无关(P>005)。提示血清sIL2R水平检测对肺癌的诊断及病情变化、疗效观察有一定价值。 相似文献
16.
Treatment of early giant retinal tears with domestic perfluorodecalin and perfluoropropane 总被引:4,自引:0,他引:4
ObjectiveToexplorethemethodsoflenssparing(withoutlensectomy),nonsiliconeoiltamponadeandnoscleralbucklingfortreatmentofearly... 相似文献
17.
Effects of Kupffer cells stimulated by triglyceride and very low-density lipoprotein on proliferation of rat hepatic stellate cells 总被引:4,自引:1,他引:3
ObjectiveTostudytheefectsoftriglyceride,verylowdensitylipoprotein(VLDL),andKupfercelconditionedmedium(KCCM)derivedfromtrigl... 相似文献
18.
血液透析患者细胞因子变化及茶色素的免疫调节作用 总被引:4,自引:0,他引:4
应用ESISA方法和白细胞介素6(IL6)依赖细胞株的MTT法对血液透析患者血清IL8、sIL2R和IL6水平进行检测,同时观察用中药茶色素治疗前、后上述指标的变化。结果证实,血液透析患者IL8水平增高(P<005)、sIL2R水平显著高于正常人(P<0001),而IL6与正常人比较无显著差异(P>005)。用茶色素治疗后,IL8和sIL2R水平下降,且IL8接近正常人水平。这说明血液透析患者存在免疫功能低下,茶色素有调节免疫作用 相似文献
19.
Dietary L-arginine attenuates expression of vascular cell adhesion molecule-1 in the aortae of hypercholesterolemic rats 总被引:3,自引:0,他引:3
ObjectiveTodeterminewhethertheantiatherogenicefectofLarginineisduetoaninhibitionofvascularceladhesionmolecule1(VCAM1)expre... 相似文献
20.
Blocking effect of puerarin on calcium channel in isolated guinea pig ventricular myocytes 总被引:10,自引:0,他引:10
Objective ToidentifywhetherPuerarin(Puer)hasblockingeffectsonLtypecalciumchannelMethods WeusedwholecellrecordingofpatchclamptechniquestoanalysecalciumchannelcurrentinventricularmyocytesisolatedfromLangendorffguineapigheartsbycollagenaseResults I… 相似文献