Coolant oil dermatitis due to ethylenediamine

Two outbreaks of hand dermatitis in light engineering works are reported. In both cases a number of workers shown to be allergic to soluble coolant oils were found to be allergic to ethylenediamine, which had either been incorporated into the oil or had been added to it later.     

Contact dermatitis from ethylenediamine

This study of seven patients with an allergic contact dermititis from ethylenediamine has shown that sensitisation to topical antihistamines and disodium ethylenediamine tetra-acetate is not inevitable in a allergic contact dermatitis from ethylenediamine.     

Ethylenediamine contact dermatitis

A retrospective study of 50 patients with ethylenediamine allergy revealed that 2 topical products containing ethylenediamine as a stabiliser are the main sources of sensitization in Italy. Some of these patients cross-reacted to piperazine and diethylenetriamine, but none to ethylenediamine tetracetic acid.     

T cell lymphomatoid contact dermatitis: a challenging case and review of the literature

Lymphomatoid contact dermatitis is a pseudolymphoma with clinical and histological features of allergic contact dermatitis and cutaneous T cell lymphoma. Incorrect diagnosis may lead to unnecessary testing, unnecessary treatment, or patient harm. The objective of this study is to present a case to demonstrate the diagnostic challenge and overlap between allergic contact dermatitis and cutaneous T cell lymphoma in a patient with lymphomatoid contact dermatitis caused by methylchoroisothiazolinone/methylisothiazolinone and paraben mix, and to review the existing literature in order to summarize the demographics, clinical features, allergens and treatments reported for lymphomatoid contact dermatitis. A search of major scientific databases was conducted for English‐language articles reporting cases of lymphomatoid contact dermatitis or additional synonymous search headings. Nineteen articles with a total of 23 patients were analysed. Lymphomatoid contact dermatitis was more common in men, with an average age of 58.5 years. Fourteen unique allergens were identified and confirmed by patch testing. However, no single test or study was diagnostic of lymphomatoid contact dermatitis. Allergen avoidance was the most useful management tool, but selected patients required topical or systemic immunosuppression. In conclusion, without specific diagnostic features, evaluation for lymphomatoid contact dermatitis should include a thorough history and examination, patch testing, and biopsy with immunohistochemistry and clonality studies.     

Lymphomatoid contact dermatitis *

Five elderly patients with recurrent and progressive erythematous patchy dermatitis had temporary flares of generalized erythema and associated positive patch tests. The histopathologic findings were of a distinct pattern of lymphocytic dermal reticulosis and chronic epithelial response. We believe this represents a potential pre-Sézary state that can he recognized by the course and the histologic pattern.