Calcifying odontogenic cyst with complex odontoma

A calcifying odontogenic cyst associated with a complex odontoma is described. The presence of reduced enamel epithelium showing extensive proliferation accompanied by dentinoid and enameloid formation, and the morphologic connection of the lining epithelium of the cyst with the enamel epithelium, indicate that the possible origin of the cyst is the enamel epithelium of the odontoma.     

Calcifying odontogenic cyst associated with odontoma: report of two cases

The calcifying odontogenic cyst (COC) is a nonneoplastic lesion whose possible association with other odontogenic lesions such as odontoma has been considered improbable by some authors. This paper reports two cases of true odontoma found concurrently with the COC.     

Calcifying odontogenic cyst: case report and review of literature

A case of calcifying odontogenic cyst is presented. An analysis of the previously reported cases indicates the variable clinical, radiographic and histopathologic features of the lesion.     

Erupted complex odontoma: a case report and literature review

A case involving a 17-year-old girl with a large erupted odontoma associated with a deeply impacted mandibular molar is reported. The molar, which previously had been displaced to the border of the mandible, erupted successfully three years after surgical removal of the odontoma. A review of the literature presents guidelines for treating similar cases.     

Glandular odontogenic cyst: A case report and literature review

In 1992, the World Health Organization (WHO) named glandular odontogenic cyst (GOC) as an independent pathologic entity and classified it as a developmental odontogenic epithelial cyst.^1,2 The WHO defined this lesion as “a cyst arising in the tooth-bearing areas of the jaws and characterized by an epithelial lining with cuboidal or columnar cells both at the surface and lining crypts or cyst-like spaces within the thickness of the epithelium.”¹GOCs occur over a wide age range in both sexes and in either jaw, and have the propensity to recur and to become large. Radiographically, the GOC appears as an intrabony, unilocular or multilocular, sometimes honeycomblike, well-defined radiolucent lesion. Histologically, the lining epithelium may be partly squamous, without distinctive features.¹ However, in many areas, the stratified epithelium has a surface layer of eosinophilic cuboidal or columnar cells, often forming irregular papillary projections.¹ A variable number of ciliated and mucus-producing cells may also be interspersed in the surface layer.¹ Within the thickness of the epithelium there may be crypts and glandular or cystlike spaces lined by cells similar to those seen in the epithelial surface.¹ Pools of mucous material within the intraepithelial spaces and within the main cyst cavity are a prominent feature. Plaquelike and whirlpoollike epithelial thickenings also may be present.¹ The fibrous capsule is usually free of inflammatory cells.¹ Multicystic or botryoid varieties also occur.¹ Because this lesion has been characterized only recently, and only a few cases have been reported in the literature,^3–8 its biologic nature is uncertain.^1,2 However, the aggressive behavior and the recurrent tendencies of this lesion have been suggested,^1,2 even in the limited number of reported cases.^3–8We report a case of GOC that exhibited histologic features suggesting the aggressive and somewhat neoplastic nature of this lesion. Furthermore, the clinicopathologic features of 17 cases reported in the literature^3–8 are reviewed, and the differential diagnosis of this rare lesion, especially from central low-grade mucoepidermoid carcinoma (MEC), as well as its treatment, are also discussed.     

Glandular odontogenic cyst: case report and review of the literature.

Glandular odontogenic cyst (GOC) is a rare developmental cyst of the jaws. It is included in the World Health Organization (WHO) histologic typing of odontogenic tumors under the terms glandular odontogenic cyst or sialo-odontogenic cyst. The most common site of occurrence is the anterior mandible, and it occurs mostly in middle-aged people. A predilection for men is observed. Clinical findings are not specific, and an asymptomatic swelling is frequently observed. A unilocular or multilocular, well-defined radiolucency is usually seen. The microscopic features of GOC, particularly the morphology of the epithelium, strongly suggest an origin from the remains of dental lamina. GOC has an unpredictable and potentially aggressive nature, which may indicate a high tendency of recurrence. The treatment of choice is still controversial, varying from a curettage to local block excision. A long-term follow-up should be carried out. The aim of this article is to report a case of glandular odontogenic cyst that recurred four times and to emphasize the importance of long-term follow-up. The origin, epidemiology, clinical and radiographic aspects, and treatment of the GOC are also discussed.     

Calcifying epithelial odontogenic tumor with intracranial extension: report of a case and review of the literature

The calcifying epithelial odontogenic tumor (CEOT) is a rare benign neoplasm, possibly of stratum intermedium origin and occurring predominantly in the mandible of adults. The treatment varies, depending on its size, location, and histology. A case of an advanced CEOT arising in the maxilla with intracranial extension is reported. The report is supplemented by a review of the literature.     

Extraosseous calcifying odontogenic cyst: report of case and review of literature

A case report of an extraosseous calcifying odontogenic cyst (COC) that appeared clinically to be a reactive lesion is presented. Review of the 28 previously published extraosseous COC cases and the current case report showed a mean age of 45.2 years at the time of diagnosis. No predilection for either gender or the maxilla or mandible was ascertained. A majority (51.9%) of cases occurred between the canines and none was posterior to the first molar. Because recurrences of an extraosseous COC have not been reported, the recommended treatment for an extraosseous COC is conservative surgical excision.     

Calcifying epithelial odontogenic tumour associated with dentigerous cyst

A case of calcifying epithelial odontogenic tumour is described. Provisional diagnosis based on the radiographical and clinical observations was that of a dentigerous cyst. Microscopical examination revealed features similar to that of CEOT in addition to the epithelial cyst lining.     

Calcifying odontogenic cyst with ameloblastic fibroma: report of three cases

Although it is a rare event, odontogenic tumors such as ameloblastoma, ameloblastic fibroma (AF), ameloblastic fibro-odontoma, and odontoma have been reported associated with calcifying odontogenic cyst (COC). There are only four cases of COC with AF cited in the English literature. However, three of these four cases were either included in a review of a series of cases or reported as an abstract, and limited clinical and histological information was provided. We present three additional cases of COC with AF and discuss the management for this combined lesion. Because COC is known for its histologic diversity and variable clinical behavior, and the clinical significance of an association of COC with AF is still unknown, we think it is valuable to report COC with AF with detailed clinical and pathological documentation.