正畸治疗对儿童龋病活跃性影响

目的：通过对直丝弓固定矫治的17例恒牙列儿童在正畸治疗前及正畸治疗过程中龋病活跃性的检测，了解固定矫治对儿童龋病活跃性的影响。方法：采用菌斑内细菌计数、菌斑耐酸性及产酸性实验，利用SPSS统计软件进行方差分析，并分别将治疗过程中1、3和6个月的结果与治疗前进行比较。结果：治疗过程中1、3和6个月，正畸儿童口腔内总细菌数、链球菌数量、变形链球菌数，菌斑的产酸及耐酸能力均有提高。结论：戴用固定矫治器会引起正畸儿童龋病活跃性增加，而这三种方法能够较准确地检测正畸患者龋病活跃性的改变。     

两种正畸酸蚀粘接法对儿童致龋活跃性的影响

目的:通过比较传统酸蚀后粘接与自酸蚀粘接正畸固定矫治器后龋活跃性的变化,了解矫治过程中不同酸蚀粘接法与龋活跃性的关系及其诱龋活跃性的差异.方法:随机选择30例11～14岁正畸儿童,安装方丝弓固定矫正器,左侧上下牙列采用传统酸蚀粘接法,右侧牙列采用自酸蚀粘接法,通过CAT龋病活跃性检测法比较正畸前及正畸后1周、1个月、3个月和6个月的龋病活跃性度数.结果:矫治前龋活跃性度数与矫治后3个月和6个月具有显著性差异(p＜0.05);与矫治后1周和1个月无显著性差异(p＞0.05).结论:两种粘接法致龋活跃性明显不同,传统法致龋活跃性高于自酸蚀法.     

儿童固定矫治中龋病活跃性变化的观察

目的　观察儿童固定矫治中龋病活跃性的变化。方法　以龋病活跃性检测法对进行方丝弓固定矫正器治疗的 30例恒牙列儿童 ,分别在戴用固定矫正器之前 ,戴固定矫正器后 1周 ,1、3和6个月时 ,检测龋病活跃性度数。结果　矫治前龋病活跃性度数与矫治后 1、3、6个月的差异均有显著性 ;矫治后 1周龋病活跃性度数与矫治后 3、6个月差异亦有显著性。结论　戴用固定矫正器的儿童龋病活跃性度数增加 ,龋病敏感度增强     

正畸与正常儿童龋活性比较

目的 :本实验通过检测 61名 12～ 16岁正畸与正常儿童的龋活性 ,以了解固定矫治与龋活性的关系。方法 :行变形链球菌计数、乳酸杆菌计数、细菌产酸能力测定和唾液缓冲能力测定 ,用t检验进行统计。结果 :正常儿童组口腔内变链菌和乳杆菌数目明显少于正畸儿童组 ;而唾液 pH值和缓冲能力及细菌产酸能力 ,两组间无显著性差异 (P >0 .0 5 )。结论 :结果提示正畸儿童对龋病的易感性增加     

固定正畸儿童口腔健康状况调查

目的:了解固定正畸儿童口腔健康状况.方法:随机选择57例11～15岁错颌畸形儿童,于矫治过程中进行菌斑指数、牙龈指数和龋病检查.结果:接受固定正畸治疗的儿童菌斑指数、牙龈指数显著增高;正畸过程中患者的龋患率变化不明显.结论:接受固定正畸治疗的儿童牙周组织健康受到影响.     

正畸与正常儿童龋活性比较

目的：本实验通过检测61名12－16岁正畸与正常儿童的龋活性，以了解固定矫治与龋活性的关系。方法：行变形链球菌计数，乳酸杆菌计数，细菌产酸能力测定和唾液缓冲能力测定，用t检验进行统计。结果：正常儿童组口腔内变链菌和乳杆菌数目明显少于正畸儿童组；而唾液pH值和缓冲能力及细菌产酸能力，两组间无显著性差异（P＞0．05）。结论：结果提示正畸儿童对龋病的易感性增加。     

固定正畸儿童的牙周状况分析

目的：探讨固定正畸对儿童牙周健康的影响。方法：随机选择20例11～15岁错合畸形儿童，分别于矫治前和矫治6个月对其进行临床牙周指标检查和龈下细菌的检测。结果：接受固定正畸治疗的儿童菌斑指数、牙龈指数、牙龈探诊出血、探诊深度显著增高，龈下菌群发生变化，G^-杆菌比例显著增加，G^ 细菌比例下降。结论：接受固定矫治的儿童牙周组织的健康受到影响，应加强口腔卫生宣教，减少牙龈炎的发生和发展。     

浅析正畸托槽脱落原因

在口腔固定矫治中 ,正畸托槽的脱落给正畸医师增加了额外的椅旁操作时间 ,增加患者复诊次数 ,延长了正畸治疗的疗程甚至影响治疗效果。本文作者对 2 0 0 0～ 2 0 0 3年我院正畸固定矫治患者在治疗期间托槽脱落的情况进行了临床观察和分析 ,现介绍如下。1　临床资料选自我院正畸科 2 0 0 0～ 2 0 0 3年固定矫治病例 65人 ,共粘结托槽 115 2个 ,其中方丝托槽 10 3 4个 ,BEGG细丝托槽 118个。男性患者 2 6例 ,女性患者 3 9例 ,年龄最小为 8岁 ,最大为3 3岁。 2种托槽均选用津京釉质粘结剂 ,直接粘结技术。2　结　果表 1　不同种类托槽脱落率…     

奥丽汀健齿露对龋病活跃性的影响

目的 通过检测龋病活跃性的变化,了解奥丽汀健齿露(主要成分为鸡卵黄抗体-IgY)的被动免疫防龋效果。方法 将72名3-4岁健康幼儿随机分为2组:使用奥丽汀健齿露组和使用安慰剂组。健齿露组每日晚上睡前喷服,连服2个月为1疗程。安慰剂组同法进行。实验前、后各进行1次变形链球菌菌落的测定(Dentocult SM)、乳酸杆菌计数(Dentocult LB)和变形链球菌产酸能力的测定(Cariostat,CAT)3种龋病活跃性的检测,观察龋病活跃性的变化情况。结果 健齿露组自身实验前、后龋病活跃性的减弱差异有显著性(P<0.01);与安慰剂组比较,实验后龋病活跃性的差异有显著性(P<0.01)。结论奥丽汀健齿露能有效降低机体的龋病活跃性,在预防龋病的发生、发展中能起到一定的作用;对幼儿为一种操作简便、见效快捷的防龋新方法。     

预防措施对正畸儿童龋活性的影响

目的 检测预防措施在畸儿童龋病的影响。方法 对３１名正畸儿童采取适当龋病预防措施后,观察其龋蚀活性变化。结果 采取预防措施后无新龋发生,唾液变链菌有显著性下降。结论对正畸儿童采取龋病预防措施可有效防治龋病。     

Oral cancer: molecular technologies for risk assessment and diagnosis

Purpose: The effective biomarkers related to diagnosis, metastasis, drug resistance and irradiation sensitivity of oral cancers will help the pathologist and oncologist to determine the molecular taxonomy diagnosis and design the individualization treatment for the patients with oral cancers.     

柠檬精油对牙周致病菌抑制作用及其安全性初步研究

目的:探讨柠檬精油对牙周致病菌的体外抗菌活性及对细胞增殖的影响。方法:采用微量液体稀释法测定柠檬精油对Pg、Fn、Aa、Pi的最小抑菌浓度(minimal inhibitory concentration,MIC)及最小杀菌浓度(minimum bactericidal concentration,MBC);以较低浓度的MIC为标准稀释LEO作为实验组,采用MTT法测定柠檬精油对HUVECs的毒性作用,明确抑菌浓度下LEO的安全性。结果:柠檬精油对牙周主要致病菌均有抑菌作用,Pg、Fn、Aa、Pi的MIC分别是9.0 g/L、4.5 g/L、4.5 g/L、9.0 g/L,Aa、Fn的 MBC是9.0 g/L,Pg、Pi的MBC未测得。1/2MIC、1/20MIC浓度的LEO能够抑制人脐静脉内皮细胞的生长,而低于1/200MIC浓度的LEO则对人脐静脉内皮细胞的生长没有影响,其中1/200MIC浓度的LEO作用明显优于0.02%的CHX。结论:体外环境中,柠檬精油对牙周致病菌Pg、Fn、Aa、Pi具有抗菌活性,低浓度应用对机体相对安全。     

Stimulated whole saliva components in children with Down syndrome

The authors report on the components of stimulated whole saliva from children with Down syndrome—including pH, flow rate, sialic acid and protein concentrations, and amylase and peroxidase activity. Saliva samples were collected from 35 children aged 6–10 years. Of the participants, 17 had Down syndrome and 18 did not. To stimulate saliva production, the children chewed a piece of parafilm for 10 minutes before the sample was collected. Soon after collecting the saliva sample, the authors measured pH using a portable pH-meter. Sialic acid levels were determined with a thiobarbituric acid assay. Protein content was determined with Folin's phenol reagent. Amylase was assayed and the authors measured the maltose produced by the breakdown of starch and peroxidase using ortho-dianisidine.
No statistically significant difference was observed in levels of sialic acid (free and total) between the two groups. Protein concentration was about 36% higher in the group with Down syndrome. However, the salivary flow rate, pH, and amylase and peroxidase activities were lower among the children with Down syndrome.     

Computer-assisted planning for maxillofacial prosthodontic rehabilitation

Computerized tomography (CT) planning and the use of CT derived surgical templates for implant placement have shown promise for restoring function within months after surgical reconstruction of acquired post-oncologic defects.     

牙髓再生的研究现状

目前,根管治疗术在临床上已得到了广泛的应用并成功的保存了患牙,但其仍有许多术后并发症。随着组织工程技术在口腔领域的应用,构建一种组织工程化牙髓进行牙髓-牙本质复合体的再生治疗成为可能。近年来国内外已有很多关于牙髓再生的研究,并且已经取得了一定成果。本文将对目前国内外牙髓再生的研究进展现状作一综述。     

Effect of Pingyangmycin on human venous malformation endothelial cells

Purpose: Venous malformations are common vascular anomalies with a propensity of the head and neck. Intralesional injection of Pingyangmycin (PYM, bleomycin A5 hydrochloride) is a widely used sclerotherapy method for the treatment of venous malformation.     

拔牙位点保存用复合温敏凝胶的构建及体外表征

目的:制备多壁碳纳米管/羟基磷灰石/壳聚糖复合温敏凝胶,探讨其作为拔牙位点保存材料的理化性能。方法:采用原位沉积方法制备多壁碳纳米管/羟基磷灰石(MWNT/ HA简称HAC)复合无机材料,将其分散至壳聚糖温敏凝胶中,制备壳聚糖/多壁碳纳米管/羟基磷灰石(CS /MWNT/HA简称CS/HAC)复合温敏凝胶,以成胶时间、孔径、孔隙率、机械强度及降解性能为指标优化配方设计,并表征复合温敏凝胶的微观形貌及理化性能。结果:以10 g/L的HAC作为补强成分加入到壳聚糖溶液中,能够在不影响成胶并保证一定孔隙率(84%)的前提下,提高材料的机械性能(抗压强度0.441 MPa),所获复合温敏凝胶具有适宜的临床操作时间(12 min),并具有可控的降解速率。结论:负载HAC的复合温敏凝胶具有良好的成型性,并具有较好的机械性能,在拔牙位点保存领域具有良好的应用前景。     

Oropharyngeal dysphagia in amyotrophic lateral sclerosis alters quality of life

Dysphagia is one of the most important complications encountered in amyotrophic lateral sclerosis (ALS). Our aim was to determine whether oropharyngeal dysphagia impacted the quality of life (QoL) of patients with ALS. Thirty consecutive patients were recruited (31–82 years, 18 men). Swallowing function was evaluated using a standardised videofluoroscopic barium swallow. All the patients completed a specific questionnaire on quality of life in dysphagia (SWAL‐QoL) immediately after the videofluoroscopy. The results of dysphagia outcome severity scale separated 14 patients with oropharyngeal dysphagia and 16 with normal swallowing function. There was no difference in the average age, weight and body mass index of the two groups (dysphagic patients: 68 ± 11 kg versus non‐dysphagic patients: 69 ± 14 kg). Most of the dysphagic patients had a bulbar affection based on their Norris scores which determine the importance of cranial nerves illness (20 ± 8), significantly lower than those of the non‐dysphagic patients (35 ± 5) (P < 0·0001). There was no difference in the neurological peripheral symptoms evaluated by Amyotrophic Lateral Sclerosis Functional Rating Scale scores (dysphagic patients: 26 ± 7 versus non‐dysphagic patients: 27 ± 8) (ns). The swallowing quality of life questionnaire revealed that the dysphagic patients had significant burden (P < 0·001). They were affected by the necessity to applied a food selection (P < 0·01), by the increase in eating duration (P < 0·05) and described a decrease in eating desire (P < 0·05). They complained of fear regarding the risk of dysphagia (P < 0·05). They also described difficulties with oral communication (P < 0·001). All of those complained about dysphagia which impacted directly mental health (P < 0·05) and social life (P < 0·05). In conclusion, oropharyngeal dysphagia is a common symptom accompanying ALS, which alters the patient's QoL, especially social health.     

替牙期骨性Ⅲ类错牙合患者颞下颌关节特征的锥形束CT研究

目的:采用锥形束CT(CBCT)研究替牙期骨性Ⅲ类错牙合患者颞下颌关节的影像学特征,探讨Ⅲ类功能状态下,颞下颌关节的生长、改建机制。方法:从就诊于昆明医科大学附属口腔医院正畸科的患者中选取符合纳入标准的替牙期骨性Ⅲ类错牙合患者及骨性Ⅰ类错牙合患者各20名,使用NNT viewer 5.3图像处理软件进行三维重建及线距和角度的测量,并进行统计学分析。结果:替牙期骨性Ⅲ类错牙合患者组和替牙期骨性Ⅰ类错牙合患者组对比结果为:矢状面双侧关节前间隙偏小、双侧关节上间隙偏小、双侧关节结节斜度偏小;冠状面双侧关节内间隙偏小,双侧关节上间隙偏小,双侧关节外间隙偏小,右侧髁状突角度偏小;横截面右侧髁状突前后径偏小。结论:替牙期骨性Ⅲ类错牙合患者颞下颌关节发育不充分,呈现髁状突,关节窝深度,关节结节斜度;冠状面关节内、外间隙均较小的特征。骨性Ⅲ类错牙合患者髁状突在关节窝中处于前置近关节窝顶位置。骨性Ⅲ类错牙合患者颞下颌关节影像学特征与其功能状态相适应。