共查询到20条相似文献,搜索用时 0 毫秒
1.
Do recombinant human erythropoietin and iron supplementation increase the risk of retinopathy of prematurity? 总被引:3,自引:0,他引:3
Romagnoli C Zecca E Gallini F Girlando P Zuppa AA 《European journal of pediatrics》2000,159(8):627-628
Comparing a group of infants treated with recombinant erythropoietin and iron supplementation to a group of control infants, no difference was observed concerning the transfusion need. The incidence of retinopathy of prematurity was significantly higher in the treated group. These data need to be confirmed in randomized controlled studies. 相似文献
2.
Mactier H Galloway P Hamilton R Weaver L 《The Journal of pediatrics》2005,146(6):846-7; author reply 847-8
3.
Indian Journal of Pediatrics - 相似文献
4.
5.
6.
Raman K. Marwaha Nikhil Tandon Neha Agarwal Seema Puri Rashmi Agarwal Satveer Singh Kalaivani Mani 《Indian pediatrics》2010,47(9):761-769
Objective
To determine the efficacy of supplementation with oral vitamin D3 (cholecalciferol) on bone mineral biochemical parameters of school-going girls. 相似文献7.
8.
9.
《Archives de pédiatrie》2020,27(8):490-496
Iron deficiency and iron deficiency anemia are public health issues recognised by the World Health Organisation, especially in sub-Saharan Africa. In some countries on this continent, the prevalence of anemia exceeds 60% in the pediatric population. Iron supplementation could prevent around one third of anemia cases in children in Africa and could decrease morbidity and mortality. A number of factors are behind this anemia, including iron deficiency caused by an inadequate diet, pica and geophagia, as well as chronic inflammation (malaria, digestive and urinary parasites, etc.). Ferritin is a good indicator of the body's iron stores, but it is not a specific reflection, with both inflammation and infection causing an increase. Ferritin could be interpreted according to C-reactive protein (CRP) or alpha-1 glycoprotein (AGP), or by adjusting the ferritin threshold to 30 μg/L. The treatment of malaria and digestive or urinary worms, the correction of factors that stimulate inflammation, the fight against geophagia, as well as more hygienic living conditions, are all prerequisites for overcoming iron deficiency. A number of campaigns using iron supplements have proven to be effective, especially in schools, to fight against iron deficiency and malnutrition. Biofortification is an innovative and promising cultivation technique that increases the content of bioavailable iron in local produce such as beans. It will become a lever in the fight against iron deficiency. 相似文献
10.
OBJECTIVE: To survey the attitudes and practices among level III neonatal intensive care units in the United States regarding vitamin A supplementation for extremely-low-birth-weight (ELBW; birth weight < or =1000 g) infants.Study design A pretested questionnaire regarding vitamin A supplementation was distributed to all (n=102) neonatal-perinatal training program directors (TPD) and 105 randomly selected directors of level III neonatal intensive care units (nontraining program directors, NTPD). RESULTS: Ninety-nine percent of TPD and 94% of NTPD responded. In a minority of programs (20% TPD, 13% NTPD), >90% of eligible extremely-low-birth-weight neonates are supplemented with vitamin A, whereas in most programs (69% TPD, 82% NTPD), routine supplementation is not practiced. Most centers (91% TPD, 81% NTPD) supplementing vitamin A use a dose of 5000 IU IM 3 times per week for 4 weeks. The most common reason that TPD give for not supplementing vitamin A is the perceived small benefit, whereas the most common reason for NTPD is that they consider the intervention unproven. CONCLUSIONS: These findings indicate inconsistency in practicing evidence-based medicine in neonatal practice, where therapies are often administered on the basis of weaker evidence of safety and benefit than supports vitamin A supplementation. Educational interventions may be required to endorse the benefits and safety of vitamin A supplementation. 相似文献
11.
India currently has an infant mortality rate (IMR) of 73 and aims to reach 60 per 1000 live births by 2000 A.D. The “at risk”
approach which has been traditionally used for Maternal and Child Health services could help to reduce costs. The main objective
of the study was to identity socio-demographic “risk factors” at family level for underfive deaths and assess the validity
and efficiency of a risk index scale for this purpose. A computerised database on about 71,000 individuals in 28 villages
in Ballabgarh Block exists since 1987. All the underfive deaths in the study area during the period 1991–95 were compared
with age and sex matched controls on socio-demographic variables. All variables which were found significant at 10% level
were taken in for logistic regression. The variables found significant were used to construct a ten point scale. This scaling
system was applied to all the families with an underfive child during the two year period 1996–97. Validity and efficiency
of this approach was calculated. A total of 849 cases and their age and sex matched controls were studied. The variables which
were significantly associated with risk of underfive deaths were: not received measles vaccine (2.19; 1.58–3.04), history
of sibling death (2.03; 1.19–3.45), maternal illiteracy (1.86; 1.23–2.81), never used a contraceptive (1.59; 1.17–2.14), having
more than 4 children (1.46; 1.04–2.05). About 40% of houses were labelled as high risk. The sensitivity and specificity were
around 60%. The improvement in efficiency by the risk approach was 33%. Risk approach is helpful in identifying families who
are at greater risk of having underfive deaths. It results in a modest increase in the efficiency of services. 相似文献
12.
Iron deficiency anemia (IDA) causes growth and developmental retardation in infants. Iron supplementation from the 4th month of age may prevent IDA, but side effects of oral iron supplementation limit its usage. The aim of this study was to investigate the effect of maternal iron supplementation on the iron status of mothers and their exclusively breast-fed infants. In a prospective, placebo-controlled, double-blinded randomized study, healthy mothers (Hb > or = 11 g/dl) and their 10-20-day-old healthy term infants who were admitted to Hacettepe University for neonatal screening were enrolled. The mothers who were intending to exclusively breast-feed at least up to four months were included. Iron supplementation (n = 82, 80 mg elementary iron) and placebo (n = 86) were given to the mothers randomly for four months. The anthropometrical measurements of infants were recorded monthly. Of all, 69 mothers and their infants in the iron group and 63 in the placebo group completed the study. At the end of the study period, blood samples (complete blood count, serum iron, iron binding capacity and serum ferritin) were drawn from the mothers and their infants. After adjustment for baseline hemoglobin value, the mean levels of hemoglobin, serum iron and ferritin were similar in the two groups at the end of the study; however, serum iron binding capacity was significantly lower in the iron group than in the placebo group. Giving maternal iron supplementation during the first four months of the lactation period had no effect on the serum iron and ferritin levels of mothers and infants. This could be due to the relatively short duration of the follow-up period. A longer follow-up period is recommended to detect the effect of the maternal iron supplementation during lactation. 相似文献
13.
14.
15.
Greenwood S Abdel-Latif ME Bajuk B Lui K;NSW ACT Neonatal Intensive Care Units Audit Group 《Journal of paediatrics and child health》2012,48(7):588-595
Aim: The aim of this article was to evaluate the Revised Clinical Risk Index for Babies' (CRIB‐II) severity of illness score as a predictor of moderate to severe functional disability (FD) in very premature infants. Methods: Population study of infants born <29 weeks' gestation cared for in all Neonatal Intensive Care Unit in New South Wales and the Australian Capital Territory between 1998 and 2003. FD at 2–3 years corrected age was defined as developmental delay (quotient < 2 standard deviation), non‐ambulatory cerebral palsy (needing aids to walk), blindness (acuity <6/60 in better eye) or deafness (hearing aids). Sensitivity and specificity of CRIB‐II scores to predict FD were performed by receiver operating characteristic curve analysis. Results: Of study population of 2210, 480 (21.7%) died before hospital discharge. Among 1328 infants assessed, 217 (16.3%) had FD, 109 (8.2%) developmental delay, 75 (5.6%) cerebral palsy and 54 (4.1%) blindness or deafness. CRIB‐II performed significantly better than gestation or birthweight (BW) alone in predicting mortality (area under the curve (AUC) ± standard error 0.83 ± 0.01, vs. 0.78 ± 0.01 and 0.76 ± 0.01, respectively). CRIB‐II scores were significantly higher in FD than non‐FD children (11.9 ± 2.9 vs. 10.1 ± 2.6), but the AUC for CRIB‐II (0.68 ± 0.02) did not significantly differ from that of gestation (0.65 ± 0.02) and BW (0.65 ± 0.02). Conclusion: CRIB‐II improved prediction of mortality but did not perform better than gestational age or BW in predicting FD. We would caution clinicians against using the infant's condition at admission to predict long‐term outcome. 相似文献
16.
Jane A. Batchelor 《Infant Observation》2013,16(2):101-102
Edited by Jane A. Batchelor The Children's Society 1999 ISBN 1-899783-253 Reviewed by Dr. Priti Pate1 相似文献
17.
Erman Atas Ferhan Karademır Atilla Ersen Cihan Meral Secil Aydınoz Selami Suleymanoglu Mustafa Gultepe İsmail Gocmen 《European journal of pediatrics》2013,172(8):1039-1042
The daily supplementation of vitamin D is mandatory for infants. However, there are still conflicting opinions about the exact daily dose. Thus, we aimed to evaluate a daily supplementation dose of 200 IU is sufficient and compared the supplementation doses of 200 and 400 IU per day. One hundred and sixty-nine infants were randomly assigned to two groups (group1, 200 IU/day; group 2, 400 IU/day) and there were 75 infants in group 1 and 64 were in group 2 with a total number of 139. The median levels of 25-hydroxyvitamin D3 were significantly increased in group 2 at the age of 4 months (group 1, 39.60 mcg/L; group 2, 56.55 mcg/L; p?<?0.0001). We clearly demonstrated that at the age of 4 months, none of the infants on the group 2 had a serum level of 25-hydroxyvitamin D3 less than 30 mcg/L. However, 21.3 % of the infants in group 1 had a level below 30 mcg/L. Thus, in order to avoid vitamin D deficiency and rickets, we recommend supplementation dose of vitamin D at 400 IU/day as a safe and effective dose. 相似文献
18.
19.
20.
Sudha Chaudhari Mangalmurti Bhalerao Anjali Chitale Bharati Patil Anand Pandit Mahendra Hoge 《Indian pediatrics》2010,47(11):931-935