普外科手术后39例患者疼痛观察与护理

目的 观察心理护理在普外科术后对疼痛的干预.方法 将39例普外科手术患者随机分为对照组18例,给予单纯临床常规护理;观察组21例,给予临床常规护理配合围手术期的心理护理,72h后进行疼痛率比较.结果 观察组疼痛率为47.62%,明显低于对照组的66.67%..结论 心理护理对普外科手术后疼痛有积极的治疗作用,值得临床广泛应用.     

心理护理干预对抑郁症患者康复的影响

目的 观察心理护理干预对抑郁症患者康复的影响.方法 将86例抑郁症患者按入院的先后顺序随机分为两组,对照组给予常规的治疗护理.研究组在常规治疗护理外进行8周系统的护理干预.采用汉密顿抑郁量表(HAMD)进行评定.出院1年进行随访.结果 心理干预前两组(HAMD)评分无统计学差异(P＞0.05),护理干预8周末,研究组HAMD评分明显低于对照组,服药依从性明显高于对照组,具有非常显著的统计学意义(P＜0.01).1年后研究组复发率明显低于对照组.结论 住院期间对患者实施相应的心理护理干预可提高疗效及服药的依从性,降低复发率.     

普外科手术后39例患者疼痛观察与护理

目的观察心理护理在普外科术后对疼痛的干预。方法将39例普外科手术患者随机分为对照组18例,给予单纯临床常规护理;观察组21例,给予临床常规护理配合围手术期的心理护理,72h后进行疼痛率比较。结果观察组疼痛率为47.62%,明显低于对照组的66.67%.。结论心理护理对普外科手术后疼痛有积极的治疗作用,值得临床广泛应用。     

探讨临床护理路径在住院躁狂抑郁症患者健康教育中的实施

目的：探讨临床护理路径在住院躁狂抑郁症患者健康教育中的实施效果。方法选取我院2012年11月~2013年11月接收的56例躁狂抑郁症患者作为观察对象,随机将56例患者分为观察组和对照组各28例,对照组患者接受的是常规基础护理健康教育,观察组患者采取临床护理路径护理方式给患者进行健康教育。结果观察组患者的治疗有效率明显高于对照组患者,同时观察组患者在出院时候的躁狂和抑郁程度明显比对照组轻,比较有差异性,具有统计学意义。结论针对躁狂抑郁症患者在住院期间给予临床护理路径进行健康教育,能更有效的提高患者的治疗有效率,改善患者的临床症状,临床效果显著,值得在临床上应用和推广。     

探讨护理干预对急性上消化道出血患者的影响及效果分析

目的：探讨分析对急性上消化道出血患者采取全面心理护理干预的影响和效果。方法选取2012年3月~2013年12月于我院消化内科就诊的70例急性上消化道出血患者,根据随机化的原则分成观察组和对照组各35例,对照组采取消化内科常规护理,观察组在常规护理的基础上进行全面的心理护理干预,对比分析两组患者的临床护理效果。结果治疗后观察组患者抑郁及焦虑症状缓解率显著高于对照组(P<0.05),观察组治疗总有效率显著高于对照组(P<0.05)。结论对急性上消化道出血患者采取全面心理护理干预,能显著改善患者的负面情绪,提高临床治疗有效率,护理效果好,可推广于临床护理工作中。     

心理护理及语言沟通在临床精神科护理中的作用分析

目的 探讨心理护理及语言沟通技能在临床精神科护理中的作用。方法 选取2015年3月~2017年3月在本院精神科住院的100例患者,随机分为观察组和对照组,每组50例。对照组仅采取常规物理治疗,观察组在对照组基础上辅以心理护理和语言沟通,2年后对比两组患者性格改变发生率、行为异常发生率、言语异常发生率及病情发生率,并对两组患者病情发生率进行单因素方差分析。结果 观察组的性格改变发生率、行为异常发生率、言语异常发生率及病情复发率均低于对照组,差异有统计学意义（P＜0.05）。病情发生率经单因素方差分析可知,心理护理在临床精神科治疗中有显著疗效。结论 在临床精神科护理中运用心理护理和语言沟通技能,可以有效调节患者情绪,控制患者病情,从而促进其心理康复。     

外科手术患者的心理护理体会

目的探讨心理护理对外科手术患者的临床效果。方法选取2012年10月~2013年10月来自我院接受治疗的外科手术患者160例,将其随机分为对照组和观察组各80例,对照组患者采用常规的护理方法,观察组缓则采用心理护理方法,观察对比和分析两组患者的临床疗效和患者及家属对护理人员的满意度。结果两组患者经过治疗和护理后,症状均有所改善,对照组患者治疗的总有效率为75.00%,观察组患者治疗的总有效率为97.50%,对照组患者和家属对护理人员的满意度为75.00%,观察组患者和家属对护理人员的满意度为95.00%,两组相比较,差异显著,有统计学意义(<0.05)。结论对外科手术患者进行心理护理可以提高临床效率,值得临床推广及运用。     

综合护理干预对促进抑郁症患者康复的临床效果分析

目的 探究综合护理干预对促进抑郁症患者康复的临床效果。方法 选取我院2016年1月～2017年1月收治的80例抑郁症患者进行研究。随机分为观察组和对照组,每组40例,对照组采用常规护理,观察组采用综合护理干预,对两组患者护理进行对比分析。结果 观察组患者的HRSD评分、生活质量评分以及护理满意度优于对照组,两组差异存在统计学意义（P＜0.05）。结论 综合护理干预对促进抑郁症患者康复的临床效果显著,值得在临床推广及应用。     

家庭护理干预对抑郁症患者家属心理状况的影响

目的探讨抑郁症患者家属的心理状况及护理干预方法。方法将80例抑郁症出院患者随机分为观察组（40例）和对照组（40例）,均配对选择患者一名与其生活关系密切的家属。两组患者均接受常规治疗及护理,观察组家属接受家庭护理干预,1次/周,共8周。于入组前及第8周末分别采用SCL-90及自行设计的个人心理压力和对患者病态行为的应对能力测量表进行评定。结果干预后观察组患者家属SCL-90评分中躯体化、抑郁、焦虑等因子分显著低于对照组（P均〈0.01）,且心理压力及应对能力明显提高。结论家庭护理干预对抑郁症患者家属的躯体化、焦虑和抑郁有显著的缓解作用,值得推广应用。     

精神分裂症恢复期应用团体生物反馈疗法及心理护理的效果

目的:探究精神分裂症恢复期应用团体生物反馈疗法及心理护理的效果.方法:选择2020年7月至2021年3月宿州市第二人民医院接诊的120例精神分裂症患者,按照随机数表法分为观察组与对照组,每组60例.对照组进行常规的护理内容,观察组给予团体生物反馈疗法联合心理护理治疗,两组患者均持续治疗8周.比较两组患者治疗8周后的临床...     

Improved bronchodilation with levalbuterol compared with racemic albuterol in patients with asthma

Background: Racemic albuterol is an equal mixture of (R)-albuterol (levalbuterol), which is responsible for the bronchodilator effect, and (S)-albuterol, which provides no benefit and may be detrimental. Objective: We sought to compare 2 doses of a single enantiomer, levalbuterol (0.63 mg and 1.25 mg), and equivalent amounts of levalbuterol administered as racemic albuterol with placebo in patients with moderate-to-severe asthma. Methods: This was a randomized, double-blind, parallel-group trial. Three hundred sixty-two patients 12 years of age or older were treated with study drug administered by means of nebulization 3 times daily for 28 days. The primary endpoint was peak change in FEV₁ after 4 weeks. Results: The change in peak FEV₁ response to the first dose in the combined levalbuterol group was significantly greater compared with the combined racemic albuterol group (0.92 and 0.82 L, respectively; P = .03), with similar but nonsignificant results after 4 weeks (0.84 and 0.74 L, respectively). Improvement in FEV₁ was similar for levalbuterol 0.63 mg and racemic albuterol 2.5 mg and greatest for levalbuterol 1.25 mg. Racemic albuterol 1.25 mg demonstrated the weakest bronchodilator effect, particularly after chronic dosing. The greatest increase in FEV₁ was seen after levalbuterol 1.25 mg, especially in subjects with severe asthma. All active treatments were well tolerated, and β-adrenergic side effects after administration of levalbuterol 0.63 mg were reduced relative to levalbuterol 1.25 mg or racemic albuterol 2.5 mg. At week 4, the predose FEV₁ value was greatest in patients who received levalbuterol or placebo when compared with those who received racemic albuterol. The difference was more evident and was statistically significant in patients who were not receiving inhaled corticosteroids. Conclusion: Levalbuterol appears to provide a better therapeutic index than the standard dose of racemic albuterol. These results support the concept that (S)-albuterol may have detrimental effects on pulmonary function. (J Allergy Clin Immunol 1998;102:943-52.)     

Infectious diseases and immunological markers associated with patients with non-Hodgkin lymphoma treated with rituximab

Background: The use of rituximab (RTX) is increasing, even in developing countries. It has become the first-line therapy or adjuvant to chemotherapy (CHOP; cyclophosphamide, hydroxydaunorubicin, oncovin and prednisone) for various diseases, including B cell lymphoma and autoimmune diseases.

Aim: We describe the infectious diseases and immunological markers associated with RTX treatment of patients with non-Hodgkin lymphoma (NHL).

Methods: Serum immunoglobulins were determined before and after intravenous immunoglobulin (IVIg) administration. Pneumo-23IgG-specific anti-pneumococcal antibodies were evaluated before and after vaccination. Immunophenotyping and lymphocyte proliferation were determined in the course of the treatment.

Results: Seven patients were followed and median age was 56.0?±?5.0?years (range, 41.9–71.6?years). At baseline, the mean level of IgG was 333.7?±?40.8?and IgM 40.9?±?11.3?mg/dL, respectively; immunoglobulin A and E (IgA and IgE) were under the limit of detection. Two patients had reduced or absent B cells and T cell subsets were at normal levels in five patients. All patients failed to mount an efficient post-vaccination immune response against hepatitis B virus, tetanus, diphtheria and against the 23-valent pneumococcal polysaccharide vaccine. During RTX/CHOP treatment, human-IgG-immunoglobulin (IVIg) therapy was introduced in six patients after recurrent infections, including community-acquired pneumonia (85.7%), chronic sinusitis (85.7%) and gastroenteritis (42.9%).

Conclusion: Poor response against pneumococcal vaccines increases the susceptibility of respiratory diseases in these patients. In patients with NHL treated with RTX, the benefits achieved with IVIg replacement for the control of recurrent infectious diseases is of paramount importance. Clinicians dealing with monoclonal antibodies against cancer therapy, especially RTX, should be aware of the increasing risks for symptomatic induced hypogammaglobulinemia and respiratory infections.     

Satellite RNA associated with bamboo mosaic potexvirus shares similarity with satellites associated with sobemoviruses

Summary A putative nonstructural protein encoded by a satellite RNA associated with bamboo mosaic potexvirus shares 46% identity with the capsid protein of satellite virus of panicum mosaic sobemovirus. The sequence similarity among satellite plant viruses which have no apparent relationship implies a common origin.     

拉米夫定与泛昔洛韦联合治疗乙型肝炎病毒慢性感染的临床研究

目的 观察拉米夫定与泛昔洛韦联合治疗乙型肝炎病毒(HBV)慢性感染的临床疗效。方法 慢性乙型肝炎患者90例。设联合治疗组28例，单用拉米夫定组30例，单用泛昔洛韦组32例。联合治疗组给予口服拉米夫定0．1g／d(PO)，泛昔洛韦1．5g／d(PO)，24周。拉米夫定、泛昔洛韦单用组剂量及疗程分别同联合治疗组。结果 3组均无明显副反应，丙氨酸转氨酶(ALT)复常率无差异。3组HBV DNA阴转率分别为89．3％、66．7％、40．6％，差异有显著性。乙型肝炎表面抗原(HBeAg)阴转率分别为28．6％、23．3％、21．9％，差异无显著性。结论 拉米夫定与泛昔洛韦联合用药安全、耐受性好，临床显示联合治疗对HBV DNA的抑制作用显著优于单用药。     

Gynecomastia with marked cellular atypia associated with chemotherapy

Gynecomastia is a common benign male breast disease, which may exhibit mild cellular atypia in cytology specimens. However, marked cytologic atypia can be seen in gynecomastia superimposed by chemotherapy. The case described in this report demonstrated severe cytologic atypia of gynecomastia mimicking carcinoma in a patient treated with chemotherapy for acute leukemia. A distinct cytologic feature helpful in avoiding the diagnostic error is described, namely, atypical cells admixed with bland ductal cells and appearing at a different plane. The importance of applying strict diagnostic criteria in breast cytology and clinical correlation is also emphasized.     

Intervention with epinephrine in hypotension associated with mastocytosis

The occurrence of the episodes of vasodilatory hypotension can be a life-threatening manifestation of systemic mastocytosis. This article describes the reversal by epinephrine of episodes of severe hypotension in two hospitalized patients with mastocytosis. Recognition of the efficacy of epinephrine in hypotension associated with mastocytosis can be important when other methods fail to restore hemodynamic stability.