激光倾角仪在CT引导下经皮纵隔穿刺活检中的应用北大核心CSCD

目的探讨激光倾角仪引导进针角度装置在CT引导下经皮纵隔穿刺活检中的应用价值。方法选择2017年4月至2022年4月湖北省肿瘤医院放射科CT引导下经皮纵隔穿刺活检患者100例,其中采用激光倾角仪引导下穿刺患者50例,采用常规穿刺患者50例。对比两组一次穿刺靶灶成功率、CT扫描次数、进针时间及穿刺并发症、穿刺病理阳性率。结果激光倾角仪组一次穿刺达靶灶率为74%(37/50),常规穿刺组为42%(21/50),差异有统计学意义(χ^(2)=10.509,P=0.01)。激光倾角仪组CT扫描次数为(3.42±2.05)次,常规穿刺组为(5.42±3.37)次,差异有统计学意义(t=8.502,P=0.004)。激光倾角仪组进针时间为(8.67±3.12)s,常规穿刺组为(12.08±4.70)s,差异有统计学意义(t=10.120,P=0.002)。激光倾角仪组出现并发症12例(24%),常规穿刺组出现并发症22例(44%),差异有统计学意义(χ^(2)=4.456,P=0.035)。激光倾角仪组病理阳性率为94%(47/50),常规穿刺组为92%(46/50),差异无统计学意义(χ^(2)=0.154,P=0.695)。结论激光倾角仪引导进针角度装置联合CT引导下经皮纵隔穿刺活检术可使穿刺更加精准和安全,值得临床推广应用。     

三维立体MSCT精确引导穿刺定位架在肺内肿块活检中的临床应用

目的探讨三维立体MSCT精确引导穿刺定位架在肺内肿块活检中的临床价值。方法随机抽取经皮肺穿刺病例70例并平均分为研究组(R组)与对照组(C组),两组病例内直径≤5cm病变再分为肿块组(RM组、CM组),直径5cm病变分为巨块组(RG组、CG组);研究组使用三维立体MSCT精确引导穿刺定位架引导穿刺,对照组应用传统定位栅栏CT引导穿刺,分别比较肿块组、巨块组病例的平均定位扫描次数、一次穿刺成功率、穿刺组织学符合率及并发症发生率。结果 RM组、CM组的平均定位扫描次数(不含CT定位相扫描)、一次穿刺成功率、穿刺组织学符合率分别为1.5次/2.4次(P0.05)、90.4%/63.2%(P0.05)、98.6%/90.1%(P0.05);RG组、CG组则分别为1.1次/1.5次(P0.05)、100%/93.7%(P0.05)、100%/95.1%(P0.05)。研究组与对照组发生轻微气胸分别为2例/6例(P0.05),严重气胸分别为0例/2例(P0.05),肺内轻微出血分别为1例/5例(P0.05),对照组1例出现较大肺内血肿。结论三维立体全身MSCT精确引导穿刺定位架安全性高、定位准确、一次穿刺成功率高、并发症少,尤其对于较小肿块穿刺更具优势,值得在临床工作中推广。     

CT引导下中心静脉导管置管引流心包积液的临床分析

目的 探讨CT引导下应用中心静脉导管置管引流心包积液的临床可行性、操作安全性、具体穿刺方法及相关注意事项.方法 对114例心包积液患者随机分为CT引导组(A组),超声体表定位组(B组),比较两组平均穿刺成功时间、平均穿刺次数、穿刺成功率及并发症的发生率.结果 A组第1针穿刺成功率为96.6％,B组为78.6％,P＜0.05,在穿刺成功率上两组差异有统计学意义.总并发症发生率A组为3.4％,B组为16.1％.并发症的发生两组相比差异有统计学意义.结论 在CT引导下进行中心静脉导管置管引流心包积液,成功率高、不良反应少、引流彻底、方便注药.操作安全有效,值得在临床推广应用.     

MSCT模拟三维立体定位在经皮肺穿刺活检术导航中的应用价值

目的:探讨MSCT模拟三维立体定位技术在经皮肺穿刺活检术导航中的临床应用价值。方法:选择112例胸部局限性肿块患者,随机分为实验组和对照组各56例,实验组采用MSCT三维立体定位与三维导航仪穿刺,对照组采用常规横断面内CT引导穿刺活检,比较2组一次性穿刺成功率、并发症发生率和活检诊断正确率。结果:一次性穿刺成功率实验组73.21%(41/56),对照组41.07%(23/56),2组比较差异有统计学意义(χ2=11.812,P0.05);并发症发生率实验组16.07%(9/56),对照组33.93%(19/56),2组比较差异有统计学意义(χ2=4.762,P0.05);病理确诊率实验组94.64%(53/56),对照组82.14%(46/56),2组比较差异有统计学意义(χ2=4.264,P0.05)。结论 :MSCT模拟三维立体定位,实现了术前穿刺路径的计算机模拟与三维定位,穿刺准确度与确诊率显著提高,并发症明显减少,为术中三维数据导航提供了可靠依据,具有较高的临床应用价值。     

CT三维数字化导航穿刺技术在经皮肺穿刺活检中的应用

目的 探讨CT三维数字化导航穿刺技术在肺局限性病变活检中的临床应用价值.方法 将2013年1月-2015年6月收治的212例需穿刺活检的肺部占位患者,按随机化原则分为对照组和研究组,研究组106例患者采用三维立体定位与三维导航穿刺仪活检;对照组106例患者采用CT横断面引导下常规穿刺针活检;统计分析两组的一次性穿刺成功率,并发症发生率,手术时间,诊断正确率.结果 病灶体积≤3 cm×3 cm×3 cm的患者中研究组一次穿刺成功率69.8％(37/53),对照组一次穿刺成功率22.7％(12/53)(=21.8,P＜0.01),差异有统计学意义;研究组并发症发生率18.9％(10/53),对照组并发症发生率48.9％(26/53) (x2=6.01,P＜0.05),差异有统计学意义;研究组诊断正确率96.2％(51/53),对照组诊断正确率81.1％(43/53),(x2=11.84,P＜0.05)两组比较差异有统计学意义.病灶体积＞3 cm×3 cm×3 cm的患者中研究组诊断正确率94.3％ (50/53),对照组诊断正确率79.2％ (42/53),(x2=5.27,P＜0.05)两组比较差异有统计学意义.研究组患者穿刺时间(11.6±2.8) min,对照组患者穿刺时间(22.2±6.3) min(t=-1 1.698,P＜0.01),差异有统计学意义.结论 CT三维数字化导航穿刺技术显著提高了肺部病变活检的一次穿刺成功率和诊断正确率,是一种简便、准确、安全的数字化穿刺导航新方法.     

新型专用定位弹簧圈与传统微弹簧圈定位肺小结节的对比研究

【摘要】 目的 研究新型专用定位弹簧圈与传统微弹簧圈在肺小结节胸腔镜术前定位中的临床价值。 方法 回顾性分析2018年4月至2018年12月行胸腔镜下肺组织切除术的48例肺小结节患者的临床资料,23例患者行新型专用弹簧圈术前定位,25例患者行传统微弹簧圈术前定位。记录分析患者穿刺次数、定位成功率、定位时间及CT扫描次数,统计术后并发症及术后病理结果等数据;分析比较两组定位方式统计学差异性。 结果 新型专用定位弹簧圈定位成功23例,成功率100%,传统微弹簧圈胸腔镜术前定位成功24例,成功率96.0%。两组成功率差异无统计学意义（P=0.332）;新型定位弹簧圈与传统弹簧圈定位并发症发生率差异有统计学意义（P＜0.05）;新型定位弹簧圈与传统弹簧圈差异有统计学意义（P＜0.05）定位CT扫描次数及定位时间差异有统计学意义（P＜0.05）;新型定位弹簧圈与传统弹簧圈定位穿刺次数无明显统计学差异（P＞0.05）。结论 新型专用定位弹簧圈定位相比传统微弹簧圈定位穿刺损伤更小、操作简单快捷、定位可靠不易脱落,值得临床推广。     

彩超引导与体表解剖标志定位在中心静脉置管术中的应用效果比较

目的 比较彩色多普勒超声引导与体表解剖标志定位在中心静脉置管术中的应用效果.方法 将240例行中心静脉置管术的患者根据入院先后顺序分为彩超引导组(n=120例)和体表标志定位组(n=120例),比较2组患者1次穿刺成功率、2次穿刺成功率、3次穿刺成功率、穿刺失败率、总成功率、穿刺所需时间,血气胸、血肿、静脉血栓、局部感染、导管误置等并发症发生率.结果 2组患者2次穿刺成功率、3次穿刺成功率、穿刺失败率及总成功率比较差异无统计学意义(P>0.05);但彩超引导组1次穿刺成功率(91.7%)明显高于体表标志定位组(79.2%)(P<0.05),穿刺所需时间明显短于体表标志定位组(P<0.05),彩超引导组血气胸、血肿、静脉血栓、局部感染、导管误置等并发症发生率(1.7%)明显低于体表标志定位组(11.7%)(P<0.05).结论 彩色多普勒超声引导下行中心静脉置管术可明显提高1次穿刺成功率,缩短穿刺时间,减少并发症.     

锥形束CT引导同轴穿刺在胸部肿瘤活检中的应用

目的 探讨锥形束CT的穿刺导航功能在胸部肿瘤活检中的应用价值。方法 2019年7月至12月四川省肿瘤医院行胸部肿瘤穿刺活检术(percutaneous transthoracic needle biopsy, PTNB)患者139例。比较锥形束CT的穿刺导航功能引导同轴针穿刺针与常规CT引导非同轴穿刺针在PTNB中的有效性和安全性,分析不同引导穿刺方式与病灶大小、病灶深度和手术耗时之间关系。结果 常规CT组平均耗时19.08 min,锥形束CT组平均耗时14.36 min,差异有统计学意义(t=-6.034,P<0.05)。活检时患者俯卧位平均耗时15.75 min,仰卧位平均耗时16.94 min,侧卧位平均耗时18.22 min,特殊体位平均耗时20.84 min,差异无统计学意义(P>0.05)。病灶位于不同肺段穿刺耗时比较,差异无统计学意义(P>0.05)。两组患者病灶大小、病灶深度和病灶位置比较,差异均无统计学意义(t=-1.621、-0.402、χ²=24.222,P=0.107、0.687、0.114)。穿刺次数与并发症的发生率相关...     

MSCT三维数字化导航气管隆突下间隙病变穿刺活检的研究

目的 探讨MSCT三维数字化导航技术在气管隆突下间隙病变穿刺活检中的临床应用价值.方法 将收治的82例需穿刺活检的气管隆突下间隙病变患者,随机分为对照组和研究组进行前瞻性研究,研究组41例患者采用MSCT三维数字化导航穿刺技术活检;对照组41例患者采用CT横断面引导下常规穿刺针活检;观察2组的一次性穿刺成功率,并发症发生率,手术时间,诊断正确率.结果 研究组一次性穿刺成功率87.80%(36/41),对照组一次性穿刺成功率60.97%(24/41)(χ2=8.945,P=0.005<0.05),差异有显著性意义.研究组并发症发生率14.63%(6/41),对照组并发症发生率41.45%(17/41)(χ2=7.31,P=0.007<0.05),差异有显著性意义.研究组穿刺时间(11.64±2.76) min,对照组穿刺时间(22.22±6.31) min(t=-11.70,P=-10.59<0.05),差异有显著性意义.研究组穿刺确诊率97.56%(40/41),对照组穿刺确诊率80.49%(33/41),2组比较差异有显著性意义(χ2=6.116,P=0.029 <0.05).结论 MSCT三维数字化导航技术显著提高了气管隆突下间隙病变穿刺活检的一次性穿刺成功率与穿刺精确度,降低了并发症发生率,具有较高的准确性与安全性.     

低剂量CT扫描在肺部穿刺活检术中的应用价值

目的:讨论低剂量CT扫描在胸部穿刺活检术中应用的可行性及局限性.方法:回顾分析了2009年8月至2010年9月在16排CT引导下行胸部穿刺活检术患者共80例,其中常规剂量扫描A组(200mA,重建层厚2.0mm,螺距16mm/rot)和低剂量扫描B组(10mA,重建层厚2.0mm,螺距23mm/rot)的患者各40例,比较两组穿刺CT扫描剂量、图像质量和穿刺结果成功率以及并发症之间的关系.结果:常规剂量扫描组CT吸收剂量加权指数CTDIw和平均剂量长度乘积DLP分别为(23.64± 2.41) mGy和(172.37-± 17.63)mGy·cm,穿刺成功率为90％;低剂量扫描组CT吸收剂量加权指数CTDIw和平均剂量长度乘积DLP分别为(1.22±0.12)mGy和(8.56±0.88)mGy·cm,穿刺成功率为85％.两组的辐射剂量差异有统计学意义(P＜0.01),而穿刺成功率差异无统计学意义(P＞0.05),图像质量分级均能满足穿刺活检的需要,均未发现严重并发症.结论:采用低剂量CT扫描引导胸部穿刺活检是一种值得推荐的技术,可以大大降低辐射剂量.     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.     

Prevalence and severity of hip and groin pain in sub‐elite male football: a cross‐sectional cohort study of 695 players

The purpose of this study was twofold: (a) to investigate the prevalence of hip and groin pain in sub‐elite male adult football in Denmark and (b) to explore the association between prevalence and duration of hip and groin pain in the previous season with the Copenhagen Hip and Groin Outcome Score (HAGOS) in the beginning of the new season. In total 695 respondents from 40 teams (Division 1–4) were included. Players completed in the beginning of the new season (July–Sept 2011) a self‐reported paper questionnaire on hip and/or groin pain during the previous season and HAGOS. In total 49% (95% CI: 45–52%) reported hip and/or groin pain during the previous season. Of these, 31% (95% CI: 26–36%) reported pain for >6 weeks. Players with the longest duration of pain during the previous season had the lowest HAGOS scores, when assessed at the beginning of the new season, P < 0.001. This study documents that half of sub‐elite male adult football players report pain in the hip and/or groin during a football season. The football players with the longest duration of pain in previous season displayed the lowest HAGOS scores in the beginning of the new season.     

Bronchial stump fistula :treatment with covered retrievable hinged metallic stents-preliminary clinical experience

Objective To evaluate the preliminaily clinical efficacy and retrievability of a retrievable hinged covered metallic stent in the treatment of the bronchial stump fistula （BSF）. Methods Between April 2003 and March 2005, 8 patients with bronchial stump fistula after pneumonectomy or lobectomy were treated with two types （A and B） of retrievable hinged covered metallic stents. Type A stent was placed in 6 patients and type B in 2 under fluoroscopic guidance. The stent was removed with a retrieval set when BSF was healed or complications occurred. Results Stent placement in the bronchial tree was technically successful in all patients, without procedure-related complications. Immediate closure of the BSF was achieved in all patients after the procedure. Stents were removed from all patients but one. Removal of the stents was difficult in two patients due to tissue hyperplasia. Patients were followed up for 6 - 21 months. Placement of the stents remained stable in all patients except one due to severe cough. Permanent closure of BSF was achieved in 7 （87.5%） of 8 patients. Conclusion Use of a retrievable hinged covered expandable metallic stent is a simple, safe, and effective procedure for closure of the BSF. Retrieval of the stent seems to be feasible. （J Intervent Radiol, 2007, 16： 253-257）