Effect of primary posterior continuous curvilinear capsulorhexis on clinical performance of ACR6D SE single-piece hydrophilic acrylic intraocular lenses

PURPOSE: To evaluate the effects of a primary posterior continuous curvilinear capsulorhexis (PCCC) on the clinical performance of a single-piece hydrophilic acrylic intraocular lens (IOL) with haptic angulation. SETTING: Department of Ophthalmology, Medical University of Vienna, Vienna, Austria. METHODS: A prospective study of 52 patients with bilateral age-related cataract was conducted. Patients had standard cataract surgery with implantation of the same IOL in both eyes. Randomly, a PCCC was created in 1 eye and the posterior capsule was left intact in the fellow eye. Assessed parameters were visual axis opacification (VAO) in eyes with a PCCC or regeneratory posterior capsule opacification (PCO) in eyes without PCCC (scale 0 to 10) in the central (3.0 mm eccentricity), intermediate (3.0 to 4.5 mm eccentricity), and peripheral (>4.5 mm eccentricity [capsulorhexis edge]) areas; neodymium:YAG (Nd:YAG) laser capsulotomy or laser polishing of ongrowing lens epithelium; anterior capsule opacification (ACO); best corrected visual acuity (BCVA); and contrast sensitivity. RESULTS: Thirty patients completed the 2(1/2)-year follow-up. Visual axis opacification was significantly lower in the central region in the PCCC group (mean 0.5 +/- 0.7 [SD]) than PCO in the central region of the non-PCCC group (mean 1.1 +/- 1.1) (P = .02). Forty percent in the non-PCCC group had an Nd:YAG laser capsulotomy during the follow-up period; none in the PCCC group had laser polishing. There were no significant differences in ACO, SE, BCVA, or contrast sensitivity. There was no additional gain in BCVA or contrast sensitivity in eyes with a PCCC compared with eyes without a PCCC when VAO and PCO were low. CONCLUSION: A PCCC significantly reduced PCO formation within the central 3.0 mm eccentricity as well as the need for Nd:YAG laser capsulotomy in eyes with a single-piece hydrophilic acrylic IOL with angulated haptics.     

Comparison of posterior capsule opacification rates between hydrophilic and hydrophobic single-piece acrylic intraocular lenses

PURPOSE: To determine the effect of intraocular lens (IOL) material on the development of posterior capsule opacification (PCO) at 1 year. SETTING: Department of Ophthalmology, St. Thomas' Hospital, London, United Kingdom. METHODS: One hundred six eyes of 53 patients with bilateral cataract and no other ocular comorbidity were prospectively randomized to receive a hydrophobic acrylic or hydrophilic acrylic single-piece IOL in the first eye to have surgery. The alternate IOL was implanted in the fellow eye 4 to 6 weeks later. All surgery was performed by a single surgeon. Postoperative follow-up was 1 day, 1 and 6 months, and 1 year. At each visit, the best corrected high- and low-contrast visual acuities were assessed and a high-intensity digital retroillumination photograph was taken. Posterior capsule opacification was assessed from the digital images by a single operator using a dedicated software program and calculated as the percentage area of opacified capsule. RESULTS: One year postoperatively, the median percentage area of PCO was 50.3% in the hydrophilic IOL group and 4.9% in the hydrophobic IOL group (P<.001). The difference in PCO was not accounted for by loss of contact between the capsulorhexis and IOL surface. Further analysis showed that lens epithelial cells tended to invade the posterior capsule at the haptic-optic junction. This was more marked in the hydrophilic IOL group. CONCLUSIONS: The rate of PCO was significantly higher with the hydrophilic IOL. However, the results cannot be attributed to the IOL material alone as they show the importance of both IOL material and design.     

Comparison of sulcus implantation of single-piece hydrophilic foldable acrylic and polymethylmethacrylate intraocular lenses in eyes with posterior capsule tear during phacoemulsification surgery

PURPOSE: To compare the results of sulcus implantation of acrylic and poly(methylmethacrylate) (PMMA) intraocular lens (IOL) in eyes with posterior capsule tear during phacoemulsification surgery. METHODS: In all eyes a posterior capsule tear developed during phacoemulsification surgery and an IOL to the ciliary sulcus was implanted primarily. A total of 89 eyes of 88 patients received hydrophilic foldable acrylic IOL (acrylic group). A total of 72 eyes of 72 patients received PMMA IOL (PMMA group). The mean age was 67.1 years and 68.1 years and postoperative follow-up period was 19.2 months and 17.9 months in acrylic and PMMA groups, respectively. RESULTS: Temporary corneal edema appeared in 33 eyes and 26 eyes, elevation of intraocular pressure in 17 eyes and 12 eyes, anterior chamber inflammatory reaction in 5 eyes and 5 eyes, clinical cystoid macular edema in 7 eyes and 12 eyes, and decentered IOL in 4 eyes and 3 eyes in acrylic and PMMA groups, respectively. Late postoperative endophthalmitis developed in two eyes of the PMMA group. Rhegmatogenous retinal detachment developed in one eye in each group. Final best-corrected visual acuities were 5/10 and above in 73 eyes (82.02%) in the acrylic group and 5/10 and above in 42 eyes (58.33%) in the PMMA group. Postoperative final induced astigmatism was 0.5+/-0.5 D (SD) in the acrylic group and 1.11+/-0.65 D (SD) in the PMMA group (p=0.0001) (independent samples t-test). CONCLUSIONS: Increased astigmatism is more frequently seen in the PMMA group. The implantation of foldable acrylic IOL in the sulcus after posterior capsule tear maintains the advantages of small incision surgery.     

白内障术中后囊破裂的Ⅰ期后房型人工晶状体植入术

目的评价白内障囊外摘出术中后囊破裂行前段玻璃体切割联合Ⅰ期后房型人工晶状体植入的手术效果。方法对１４８０例白内障囊外摘出联合后房型人工晶状体植入术中４９例后囊破裂,行前段玻璃体切割联合Ⅰ期后房型人工晶状体植入的手术技巧、术后并发症和术后视力等进行分析。结果手术后囊破裂率为３．３％,７０％患者人工晶状体植入囊袋内,３０％患者为睫状沟,８９．９％患者出院时裸眼视力≥０．５。结论白内障囊外摘出术中后囊破裂,行前段玻璃体切割联合Ⅰ期后房型人工晶状体植入是安全有效的。     

1140眼后囊膜连续环形撕囊术的临床体会

目的总结1140眼Ⅰ期后囊膜连续环形撕囊术的临床经验。方法884例1140眼行白内障超声乳化吸除或白内障囊外摘除联合人工晶状体植入同时进行后囊膜连续环形撕囊术。其中白内障超声乳化吸除术861眼,白内障囊外摘除术279眼。随访1m-91m。结果视力在1.0以上者309眼占27.1%,0.5-0.9者586眼占51.4%,0.1-0.4者225眼占19.7%,0.1以下者2O眼占1.8%。新生膜52眼,发生率4.6%。行新生膜切开术9眼,切开率0.8%。手术主要并发症有玻璃体内脱出。结论Ⅰ期后囊膜连续环形撕囊术是降低白内障手术后后囊膜混浊的一种简便、安全、有效的方法。因其可能的并发症和对操作的较高要求,临床应用须谨慎。     

儿童白内障摘除人工晶状体植入术联合连续环形撕后囊术

目的 评价儿童性白内障摘除人工晶状体植入联合连续环行撕后缀的临床疗效。方法 通过对25例(35眼)儿童性向内障摘除人工晶状体植入联合连续环行撕后囊术,观察后发障等并发症的发生率及视力情况。结果 发现本组儿童性白内障术后脱盲率为 90％,脱残率为 67％,后囊再次混浊 2眼(撕囊口玻璃体增殖)为 6％。结论 儿童性白内障摘除人工晶状体植入联合连续环行撕后囊术,可以有效地防止后发性白内障的发生,保持视轴清亮,绝大部分的患儿术后视力显著提高。     

儿童白内障Ⅰ期后囊连续环形撕囊临床观察

目的：探讨Ⅰ期后囊连续环形撕囊对儿童后发障的预防作用。方法：对42例（48只眼）在植入人工晶状体前施行Ⅰ期后囊连续环形撕囊，术后随访2个月至2年。结果：术后矫正视力≥0．5者有21只眼，占48．3％，随访期间有40只眼（83．3％）保持中央视轴区透明或基本透明。术后未发现严重并发症。结论：儿童白内障摘除联合人工晶状体植入术中施行Ⅰ期后囊连续环形撕囊，安全有效，在一定程度上可减少后囊混浊的发生。     

Comparison of posterior capsular opacification in heparin-surface-modified hydrophilic acrylic and hydrophobic acrylic intraocular lenses

Purpose  To compare posterior capsular opacification (PCO) in a heparin-surface-modified (HSM) hydrophilic acrylic intraocular lens (IOL) and a hydrophobic acrylic IOL. Methods  Seventy-eight patients with simple cataract were randomized to receive either the BioVue 3 HSM hydrophilic acrylic IOL (Ophthalmic Innovations International, Ontario, CA, USA) (n = 38) or the Sensar AR40e hydrophobic acrylic IOL (AMO, Santa Ana, CA, USA) (n = 40). Another 99 patients with complicated cataract received either the BioVue 3 (n = 49) or the Sensar AR40e IOL (n = 50). Twelve months after surgery, POCOman software was used to analyze digital retroillumination photographs of the PCO. Results  In the simple cataract group, the respective PCO areas, expressed as a percentage and PCO severity scores at 12 months were 6.12% and 0.081 in the BioVue 3 group and 5.91% and 0.075 in the Sensar AR40e group. There was no statistically significant difference in the PCO area or the PCO severity score between the two IOLs (P = 0.631, P = 0.495, respectively). In the complicated cataract group, the respective PCO areas and PCO severity scores were 35.80% and 0.181 in the BioVue 3 group and 27.17% and 0.110 in the Sensar AR40e group. There was no statistically significant difference between the two IOLs (P = 0.147, P = 0.162). Conclusion  There was no difference in the degree or severity of PCO between the HSM hydrophilic acrylic IOL and the hydrophobic acrylic IOL groups.     

儿童自内障Ⅰ期后囊连续环形撕囊的临床分析

目的探讨儿童白内障Ⅰ期后囊连续环形撕囊的应用价值。方法127例179眼儿童白内障进行连续环形撕囊术，术后随访2个月～2a。结果术后除42例57眼（占31．8％）不合作未能测视力外，其余矫正视力≥0．5者69眼（39．1％）。随访期间160眼（89．4％）中央视轴区保持透明，未发现严重并发症。结论Ⅰ期后囊连续环形撕囊是预防儿童白内障术后后囊膜混浊的可行方法。[眼科新进展2006；26（3）：208—209]     

儿童白内障I期后囊连续环形撕囊的临床分析

目的探讨儿童白内障I期后囊连续环形撕囊的应用价值。方法127例179眼儿童白内障进行连续环形撕囊术,术后随访2个月~2a。结果术后除42例57眼(占31·8%)不合作未能测视力外,其余矫正视力≥0.5者69眼(39·1%)。随访期间160眼(89.4%)中央视轴区保持透明,未发现严重并发症。结论I期后囊连续环形撕囊是预防儿童白内障术后后囊膜混浊的可行方法。     

Incidence of posterior capsule opacification in eyes with and without posterior chamber intraocular lenses

The incidence of posterior capsule opacification after extracapsular cataract extraction was significantly lower in eyes implanted with posterior chamber intraocular lenses than in nonimplanted eyes. The number of loops fixated in the bag was significantly smaller in the eyes that became opacified than in those that did not. These findings suggest that the posterior chamber lens suppresses the two processes that lead to opacification: the development of a ring-shaped opacity at the site of contact between the anterior capsule rim and the posterior capsule and the migration of lens epithelial cells toward the center of the capsule. These suppressive effects were greater when the posterior chamber lens was fixated in the bag.     

后囊连续环形撕囊治疗超声乳化术中后囊破裂的疗效观察

目的：：观察白内障超声乳化术中出现后囊破裂行后囊连续环形撕囊( PCCC)的临床效果。方法：对2013-03/10的38例38眼年龄相关性白内障患者行白内障超声乳化,术中出现后囊破裂的患者行后囊连续环形撕囊联合人工晶状体植入术;同期随机选择50例50眼年龄相关性白内障患者行白内障超声乳化联合人工晶状体植入术作为对照组,比较两组患者术后视力及其术后并发症情况,随访3 mo。结果：两组患者术后第1d视力、角膜水肿差异有统计学意义(P<0.05),术后3mo视力及角膜水肿差异无统计学意义(P>0.05);术后第1d眼压升高差异无统计学意义(P>0.05),术后3mo瞳孔及黄斑囊样水肿、视网膜脱离差异无统计学意义。结论：对于超声乳化术中发生后囊破裂的患者术中及时使用后囊连续环形撕除,能减少术后并发症发生,有效提高白内障术后效果。