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1.
Gorenstein C Rennó J Vieira Filho AH Gianfaldoni A Gonçalves MA Halbe HW Fernandes CE Demétrio FN 《Archives of women's mental health》2011,14(5):367-373
This study aimed to evaluate the effect of estrogen replacement therapy on verbal cognitive performance of middle-aged postmenopausal
women. Middle-aged (40 to 59 years) hysterectomized, oligosymptomatic women receiving 0.625 mg/day of conjugated equine estrogens
(N = 27) or placebo (N = 32) in a double-blind parallel group design were compared according to their performance on a verbal memory battery before
and after six 28-day cycles of treatment. Both groups had similar age and educational level. The estrogen group performed
better on digit span-forward and on the recall of the easy stimuli on the verbal-paired associates test regardless of age,
education, physical symptoms, number of years of menopause, or blood estradiol levels. However, the small magnitude of difference
in the effect on attentional span suggests that the estrogen-related improvement is unlikely to be of clinical relevance.
Estrogen replacement therapy did not improve verbal memory in middle-aged, hysterectomized, postmenopausal, asymptomatic women. 相似文献
2.
The aim of this study was to explore the role of affect management in postpartum relapse to smoking. Between January and October
2005, 65 women who smoked prior to pregnancy but not during the last month of pregnancy were recruited from Brigham and Women’s
Hospital in Boston, MA, and followed for 24 weeks. Surveys administered at baseline, 2, 6, 12, and 24 weeks postpartum assessed
smoking status and symptoms of depression (Beck Depression Inventory, BDI) and anxiety (Beck Anxiety Inventory, BAI). Qualitative
interviews were conducted when women relapsed or achieved an elevated BDI or BAI score. Elevated BDI or BAI scores did not
predict relapse, suggesting that symptoms that make women vulnerable to relapse may not be fully captured by these instruments.
Women described feelings of anger or frustration as part of the relapse experience. Women with elevated BDI or BAI scores
who did not relapse were more likely to normalize their mood symptoms as part of the postpartum experience and described more
adaptive and active coping strategies. Interventions designed to prevent postpartum relapse to smoking may need to target
a broader range of negative affect and mood management strategies to increase the likelihood of efficacy. 相似文献
3.
Improvement of postmenopausal depressive and anxiety symptoms after treatment with isoflavones derived from red clover extracts 总被引:1,自引:0,他引:1
Markus Lipovac Peter Chedraui Christine Gruenhut Ana Gocan Maria Stammler Martin Imhof 《Maturitas》2010
Objective
To evaluate the effect of isoflavones derived from red clover extracts (MF11RCE) over anxiety and depressive symptoms among postmenopausal women.Methods
One hundred and nine postmenopausal women aged 40 or more were randomly assigned to receive two daily capsules of MF11RCE (80 mg red clover isoflavones, Group A) or placebo of equal appearance (Group B) for a 90-day period. After a washout period of 7 days, medication was crossed over and taken for 90 days more. Anxiety and depressive symptoms were measured at baseline, 90 and 187 days with the Hospital Anxiety and Depression Scale (HADS) and Zung's Self Rating Depression Scale (SDS).Results
After receiving the MF11RCE compound the total HADS (anxiety and depression subscale scores also) and the total SDS scores decreased significantly. This effect was equivalent to a 76.9% reduction in the total HADS score (76% for anxiety and 78.3% for depression) and an 80.6% reduction in the total SDS score. After placebo, total HADS (anxiety and depression subscale also) and total SDS scores also decreased significantly in comparison to baseline but only equivalent to an average 21.7% decline.Conclusion
Red clover derived isoflavones (MF11RCE) were effective in reducing depressive and anxiety symptoms among postmenopausal women. 相似文献4.
OBJECTIVES: Hypoestrogenism occurring in association with the menopause may result in the development of vasomotor symptoms and it may also have a detrimental effect on psychological well being and quality of life (QOL). The aims of this study were to measure menopausal symptoms, mood and QOL in postmenopausal Chinese women and to assess the effect of different doses of oestrogen on these outcome indicators. METHODS: A prospective, randomized, placebo-controlled study of the effect of 1 and 2 mg oestradiol on menopausal symptoms, anxiety and depressive symptoms, and QOL in 152 postmenopausal women over a 12 month study period. Menopausal symptoms were measured using a modified Kupperman's scale. Anxiety and depressive symptoms and QOL were measured using the Hospital Anxiety and Depression Scales and a modification of the World Health Organization Quality of Life questionnaire, respectively. RESULTS: Baseline scoring of vasomotor symptoms in our population was low whilst QOL scoring was relatively high. Over 12 months, after adjustment for differences in baseline scoring, there was a significant reduction in menopausal symptom scores in the 2 mg oestradiol group compared with placebo but not in the 1 mg group. There were no statistically significant changes in levels of anxiety and depression or QOL in either the 1 or the 2 mg group compared with placebo. CONCLUSIONS: These results suggest that relatively few Chinese women will be expected to benefit from hormone replacement in terms of either QOL or mood. In addition, the overall benefit of treatment for vasomotor symptoms will be less for a given number of Chinese women than for Caucasians. Therefore, when considering the reasons for prescribing hormone replacement therapy in this population, protection against osteoporosis will for most women be the prime consideration. 相似文献
5.
Mood effect of raloxifene in postmenopausal women 总被引:4,自引:0,他引:4
OBJECTIVE: Some experimental and observational data suggest a role of estrogen in depression. Raloxifene is a selective estrogen receptor modulator (SERM) approved for the prevention and treatment of postmenopausal osteoporosis. Its influence on mood in postmenopausal women has not been fully established. Thus, we investigated the effect of raloxifene on mood. METHODS: In a randomized double-blind osteoporosis prevention study, the action of raloxifene on mood was assessed in a subgroup of non-depressed postmenopausal women (mean age: 58.9 years) receiving raloxifene 60 mg/day (n=18) or placebo (n=18). The Hamilton Depression Rating Scale (HDRS) was applied to evaluate mood 3 and 12 months following treatment. RESULTS: Baseline HDRS scores were not different among treatment groups. Overall scores decreased from baseline at 3 and 12 months in the raloxifene group (P相似文献
6.
Knekt P Lindfors O Härkänen T Välikoski M Virtala E Laaksonen MA Marttunen M Kaipainen M Renlund C;Helsinki Psychotherapy Study Group 《Psychological medicine》2008,38(5):689-703
BACKGROUND: Insufficient evidence exists for a viable choice between long- and short-term psychotherapies in the treatment of psychiatric disorders. The present trial compares the effectiveness of one long-term therapy and two short-term therapies in the treatment of mood and anxiety disorders. METHOD: In the Helsinki Psychotherapy Study, 326 out-patients with mood (84.7%) or anxiety disorder (43.6%) were randomly assigned to three treatment groups (long-term psychodynamic psychotherapy, short-term psychodynamic psychotherapy, and solution-focused therapy) and were followed up for 3 years from start of treatment. Primary outcome measures were depressive symptoms measured by self-report Beck Depression Inventory (BDI) and observer-rated Hamilton Depression Rating Scale (HAMD), and anxiety symptoms measured by self-report Symptom Check List Anxiety Scale (SCL-90-Anx) and observer-rated Hamilton Anxiety Rating Scale (HAMA). RESULTS: A statistically significant reduction of symptoms was noted for BDI (51%), HAMD (36%), SCL-90-Anx (41%) and HAMA (38%) during the 3-year follow-up. Short-term psychodynamic psychotherapy was more effective than long-term psychodynamic psychotherapy during the first year, showing 15-27% lower scores for the four outcome measures. During the second year of follow-up no significant differences were found between the short-term and long-term therapies, and after 3 years of follow-up long-term psychodynamic psychotherapy was more effective with 14-37% lower scores for the outcome variables. No statistically significant differences were found in the effectiveness of the short-term therapies. CONCLUSIONS: Short-term therapies produce benefits more quickly than long-term psychodynamic psychotherapy but in the long run long-term psychodynamic psychotherapy is superior to short-term therapies. However, more research is needed to determine which patients should be given long-term psychotherapy for the treatment of mood or anxiety disorders. 相似文献
7.
Hannah Woolhouse Stephanie Brown Ann Krastev Susan Perlen Jane Gunn 《Archives of women's mental health》2009,12(2):75-83
Access to treatment for postnatal anxiety and depression is dependant on women seeking help for psychological symptoms. The
aim of this paper was to investigate what women themselves say about seeking help for emotional difficulties after childbirth.
The Maternal Health Study is a prospective pregnancy cohort study investigating the physical and psychological health of 1,507
nulliparous women during pregnancy and after birth. One thousand, three hundred eighty-five women completed a computer-assisted
telephone interview at 9 months postpartum; 8.5% of women reported intense anxiety or panic attacks occasionally or often,
and 9.5% reported depressed mood, between 6 and 9 months postpartum. Of those experiencing anxiety symptoms alone 44.4% had
spoken to a health professional, compared with 65.5% of women experiencing depressive symptoms alone (RR = 0.68, 95% CI—0.5
to 0.9). Measures of anxiety and depressive symptoms at 9 months postpartum were not validated against diagnostic criteria.
Anxiety is a common experience in the perinatal period. More research is needed into this area to determine what levels of
anxiety are ‘normal’ and acceptable to women during this period. Public health campaigns may have been more effective in encouraging
women to seek help for depression than anxiety. 相似文献
8.
OBJECTIVE: To compare the effects of (i) continuous low dosage C-19 progestin (dl-norgestrel, NG) plus cyclical conjugated estrogen (CEE) versus (ii) continuous low dosage C-21 progestin [medroxyprogesterone acetate (MPA)] plus CEE on postmenopausal vaginal bleeding, mood and somatic, psychosomatic and psychological symptoms. METHODS: Nine hypercholesterolemic postmenopausal women with intact uteri were randomly assigned in a prospective, double-blind, two-period cross-over study of CEE (25/28 days) plus either (i) NG, (0.05 mg/day) or (ii) MPA (2.5 mg/day) for 1 year and after an appropriate wash-out period were switched to the alternative regimen for another year. Four hysterectomized control subjects received the CEE only. RESULTS: Administration of CEE + MPA versus CEE + NG resulted in a significantly higher percent of cycles which were free of vaginal bleeding (97 vs 85%), spotting (92 vs 79%) and either spotting or bleeding (92 vs 76%, P < 0.01). All three regimens significantly reduced the overall combined scores for postmenopausal somatic, psychosomatic and psychological symptoms (P < 0.05). CONCLUSIONS: Vaginal bleeding and/or spotting were significantly less frequent with CEE + MPA versus CEE + NG. However, each of the three hormonal regimens improved mood and significantly reduced postmenopausal symptoms in comparison to untreated control values. 相似文献
9.
This study investigated the association between psychosocial stress and outcome of in-vitro fertilization and gamete intra-Fallopian transfer treatment. Ninety women, enrolled for treatment at a private infertility clinic, completed two self-administered psychometric tests (Bi-polar Profile of Mood States, POMS; and State-Trait Anxiety Inventory, STAI) and a questionnaire to ascertain demographic and lifestyle characteristics before the start of treatment. Approximately 12 months later an outcome measure was determined for each participant in terms of whether she was pregnant or not pregnant and the number of treatment cycles undertaken to achieve clinical pregnancy. The women's scores on the psychological tests were similar to published normative scores. On univariate analysis, history of a previous pregnancy was positively related to the probability of pregnancy and full-time employment, a more 'hostile' mood state and higher trait anxiety were associated with a lower cumulative pregnancy rate. A Cox multiple regression model found previous pregnancy history, trait anxiety, and the POMS agreeable-hostile and elated-depressed scales to be the most important lifestyle and stress variables predictive of pregnancy. The results emphasize the importance of psychosocial stress in treatment outcome but indicate that the relationships are complex. Further studies are required to validate whether these findings can be generalized to other populations. 相似文献
10.
The objective of this study was to determine the effectivenessof ovarian suppression by a GnRH agonist analogue in 32 womenwith prospectively confirmed severe premenstrual tension. Thedesign was a randomized, double-blind study comparing goserelin3.6 mg with placebo, both given as a monthly s.c. injectionfor 3 months. Self-assessment was by daily visual analogue scales(VAS) for anxiety and depression, daily quantitative symptomrating for breast discomfort, swelling, irritability, tension,depression and by monthly Hospital Anxiety and Depression (HAD)scales. Of the 16 women in each group, 15 completed active and12 completed placebo therapy. Median symptom scores for wholecycles showed a significant reduction of breast discomfort andswelling during active treatment, with no significant improvementin psychological symptoms. Analysis by cycle phase showed thatfor individual subjects, pre-treatment differences in VAS scoresfor anxiety and depression were abolished in a significantlygreater proportion of actively treated cycles. Within-groupcomparisons showed a marked placebo effect and, comparing thetwo groups, differences reached significance only during treatmentcycle 1 and the first post-treatment cycle for anxiety withno significant differences for depression. It was concludedthat while suppression of ovarian activity with a gonadotrophin-releasinghormone analogue dampens down cyclical mood swings, it has amore marked effect on the physical components of the premenstrualsyndrome. Results reconfirm the positive role of placebo inthe management of this condition. 相似文献
11.
Caroline Lilliecreutz Ann Josefsson Gunilla Sydsjö 《Archives of women's mental health》2010,13(3):259-265
Around 7% of pregnant women suffer from blood- and injection phobia. The aim was to investigate if cognitive behavior group
therapy (CBT) is effective in treating pregnant women’s blood- and injection phobia. Thirty pregnant women with blood- and
injection phobia according to DSM-IV took part in an open treatment intervention. A two-session cognitive behavior group therapy
was conducted. As controls, 46 pregnant women with untreated blood- and injection phobia and 70 healthy pregnant women were
used. Repeated measures ANOVA were performed. The scores for the CBT treatment group on the “Injection Phobia Scale-Anxiety”
were reduced both after each treatment session and postpartum (p < 0.001). Anxiety and depressive symptoms were also reduced (p < 0.001). Cognitive-behavior group therapy for pregnant women with blood- and injection phobia is effective and stable up
to at least 3 months postpartum. It seems also to reduce anxiety and depressive symptoms during pregnancy. 相似文献
12.
Fusun Terzioglu Rukiye Turk Cigdem Yucel Serdar Dilbaz Ozgur Cinar Bensu Karahalil 《African health sciences》2016,16(2):441-450
ObjectiveThe aim of this study was to determine the effect of anxiety and depression scores of couples who underwent Assisted Reproductive Techniques (ART) on pregnancy outcomes.MethodThis study was conducted as a prospective and comparative study with 217 couples. The study data was collected by using a semi-structured questionnaire and the Turkish version of the State-Trait Anxiety Inventory (STAI), and Beck Depression Inventory (BDI). The questionnaire, STAI and BDI were applied to couples who initiated ART treatment. Couples'' state anxiety scores were re-evaluated after embryo transfer (ET).ResultsA significant relationship was found between the depression score of women and pregnancy outcome (p < 0.05). It was determined that anxiety scores for both men and women were higher before the ART procedure, but their anxiety scores decreased after ET (p < 0.05). Spouses of women with a negative pregnancy outcome had higher trait and state anxiety mean scores (p > 0.05) and lower depression scores (p <0.05) than spouses of women with a positive pregnancy outcome.ConclusionStudy results indicated that the anxiety and depression scores of couples who had achieved a positive pregnancy result were lower than for couples with a negative result. The results of this study will contribute to the health professionals especially to the nurses who spend the most time with couples in providing consulting services and supporting psychological status of couples during ART process in Turkey. 相似文献
13.
Nicole M. A. King Jennifer Chambers Kieran O’Donnell Samantha R. Jayaweera Catherine Williamson Vivette A. Glover 《Archives of women's mental health》2010,13(4):339-345
Anxiety and depression during pregnancy increase the risk for an adverse pregnancy outcome and neurodevelopmental problems
in the child. The aim of this study was to investigate anxiety and depression in women with a medical disorder of pregnancy
compared with control antenatal women, and any association with saliva cortisol. One hundred and twenty pregnant women (60
with a known medical disorder and 60 without, mean gestation 32 weeks) completed five self-rating questionnaires (Spielberger
State and Trait Anxiety, Edinburgh Postnatal Depression Scale (EPDS), the Adult Wellbeing Scale and a Life Events Questionnaire).
Diurnal saliva samples were obtained from 39 women with a medical disorder and 50 controls for cortisol analysis. The medical
disorders group were significantly more anxious and depressed than the controls (mean (SD)) state anxiety 40.0 (11.5) vs.
31.6 (8.8), p = 0.00; trait anxiety 39.4 (9.5) vs. 35.2 (9.2), p = 0.02; adult wellbeing 15.9 (7.5) vs. 12.3 (7.5) p = 0.01; and EPDS 9.6 (5.4) vs. 5.9 (4.8), p = 0.00). There was no difference in the life events scores between the groups. The subgroup of women suffering from hyperemesis
gravidarum had particularly high EPDS scores, (16.2 (3), n = 5, p = 0.00) compared with controls. There were no significant differences in the cortisol levels between the groups. Some women
with a medical disorder during pregnancy showed considerably elevated levels of anxiety and depression. Health professionals
need to be aware that these women need extra psychological support. 相似文献
14.
Treatment of climacteric complaints with ORG OD 14: A comparative study with oestradiol valerate and placebo 总被引:1,自引:0,他引:1
Org OD 14 (7,17-17-hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one) is a steroid possessing mixed hormonal activity, which in earlier studies has been shown to alleviate climacteric complaints and to prevent post-menopausal osteoporosis without affecting the endometrium. The effects of Org OD 14 on climacteric complaints were compared with those of oestradiol valerate (E2V) and placebo in a randomized, double-blind, cross-over study in 20 women who had been oophorectomized and hysterectomized 3–6 yr earlier as part of their treatment for cervical cancer. Each patient was treated orally for a total period of 18 wk, comprising 6 wk on each preparation. Capsules of identical appearance were given; these contained either 2.5 mg Org OD 14, 2 mg E2V or placebo. The patients' scores for symptoms and mood items on standardized rating scales were recorded at the end of each 6-wk treatment period (i.e. on days 43, 85 and 127). There were no differences between the effects of Org OD 14 and E2V on symptoms and mood items, while both compounds were more effective than placebo. Our findings confirmed that Org OD 14 is effective in ameliorating oestrogen deficiency symptoms in climacteric women. 相似文献
15.
Amnestic disturbance and posttraumatic stress disorder in the aftermath of a chemical release. 总被引:1,自引:0,他引:1
Neuropsychological assessments were performed on 70 patients referred after a Catacarb chemical release in a Northern California town. After appropriate exclusions, the 59 patients used in the final analysis were mostly White (66%), with 56% having some college level education. They were administered the: Wechsler Adult Intelligence Scale-Revised (WAIS-R), Memory Assessment Scale (MAS), Trails A and B, Stroop, Controlled Oral Word Association Test (COWAT), Fingertapping Test, Purdue Pegboard, Dynamometer, Rey 15-Item Test, Minnesota Multiphasic Personality Inventory-2 (MMPI-2), Brief Symptom Inventory (BSI), Beck Depression Index (BDI), Profile of Mood States (POMS), and Impact of Events Scale (IES) scales in addition to a health questionnaire and symptom checklist. Results indicate impaired scores on mnestic function and information processing when compared to Heaton's (1992) normative data, and the MAS norms (Williams, 1991). MMPI-2, BSI, BDI, POMS, and IES results indicate significant elevations on scales of depression, anxiety, anger, and posttraumatic stress disorder (PTSD) symptoms. The more brief tests of affect and mood appear sufficiently sensitive in measuring the dysphoric mood in group research studies. Clinical diagnoses using criteria from the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV; American Psychiatric Association, 1994) criteria indicate a prevalence of 54% PTSD and 64% Amnestic or Cognitive disturbance. New onset of dermatological, respiratory, visual, and gastrointestinal symptoms and illnesses are consistent with the chemical exposure, the PTSD may be in reaction to it, and Amnestic/Cognitive disturbance, from both an organic and functional etiology. 相似文献
16.
Mott SL Schiller CE Richards JG O'Hara MW Stuart S 《Archives of women's mental health》2011,14(4):335-343
Similar to biological mothers during the postpartum period, women who adopt children experience increased stress and life
changes that may put them at risk for developing depression and anxiety. The purpose of the current study was to compare levels
of depression and anxiety symptoms between postpartum and adoptive women and, among adoptive women, to examine associations
between specific stressors and depressive symptoms. Data from adoptive mothers (n = 147), recruited from Holt International, were compared to existing data from postpartum women (n = 147). Differences in the level of depression and anxiety symptoms as measured by the Inventory of Depression and Anxiety
Symptoms among postpartum and adoptive women were examined. Associations between specific stressors and depressive symptoms
were examined among adoptive mothers. Postpartum and adoptive women had comparable levels of depressive symptoms, but adoptive
women reported greater well-being and less anxiety than postpartum women. Stressors (e.g., sleep deprivation, history of infertility,
past psychological disorder, and less marital satisfaction) were all significantly associated with depressive symptoms among
adoptive women. The level of depressive symptoms was not significantly different between the two groups. In contrast, adoptive
women experienced significantly fewer symptoms of anxiety and experienced greater well-being. Additionally, adoptive mothers
experienced more depressive symptoms during the year following adoption when the stressors were present. Thus, women with
these characteristics should be routinely screened for depression and anxiety. 相似文献
17.
Freeman EW Sammel MD Lin H Gracia CR Kapoor S Ferdousi T 《Menopause (New York, N.Y.)》2005,12(3):258-266
OBJECTIVE: To estimate the association of anxiety with menopausal hot flashes in the early transition to menopause. DESIGN: A randomly identified, population-based cohort of midlife women followed up for 6 years to assess reproductive hormones and other physical, emotional, and behavioral factors. At enrollment, the women were premenopausal, aged 35 to 47 years, and had regular menstrual cycles in the normal range. Enrollment was stratified to obtain equal numbers of African American (n = 219) and white (n = 217) women. RESULTS: At the 6-year endpoint, 32% of the women were in the early transition stage and 20% reached the late menopausal transition or were postmenopausal. Reports of hot flashes increased with the transition stages, which were determined by bleeding patterns. At endpoint, hot flashes were reported by 37% of the premenopausal women, 48% of those in the early transition, 63% of women in the late transition, and 79% of the postmenopausal women. Anxiety scores were significantly associated with the occurrence of hot flashes and were also significantly associated with the severity and frequency of hot flashes (each outcome at P < 0.001). Compared with women in the normal anxiety range, women with moderate anxiety were nearly three times more likely to report hot flashes and women with high anxiety were nearly five times more likely to report hot flashes. Anxiety remained strongly associated with hot flashes after adjusting for menopause stage, depressive symptoms, smoking, body mass index, estradiol, race, age, and time. In a predictive model, anxiety levels at the previous assessment period and the change in anxiety from the previous assessment period significantly predicted hot flashes (P < 0.001). CONCLUSIONS: Anxiety is strongly associated with menopausal hot flashes after adjusting for other variables including menopause stage, smoking, and estradiol levels. Anxiety preceded hot flashes in this cohort. Additional studies are needed to examine the duration of menopausal hot flashes and to determine whether treatments that target anxiety effectively reduce menopausal hot flashes. 相似文献
18.
Amore M Di Donato P Papalini A Berti A Palareti A Ferrari G Chirico C De Aloysio D 《Maturitas》2004,48(2):115-124
OBJECTIVES: To provide epidemiological data about psychological symptoms derived from a large Italian non-clinical sample, and to investigate the correlation with psychosocial factors. METHODS: The study design was a cross-sectional postal survey of a sample of menopausal women recruited from the General Registry Office in Ferrara's province. Four thousands and seventy-three women were sent a questionnaire designed on the basis of the Women Health Questionnaire (WHQ). Together with the WHQ, women were asked to fill out a personal file to define social status, cultural level, family's characteristics, recent menstrual cycles, gynaecological history and operations, drug's assumption, life events in the last year and lifetime depression. RESULTS: Factor analysis resulted in eight clusters of symptoms. Among psychiatric symptoms, three different clusters were identified: depressive symptoms, depressed mood with anxiety symptoms, and anxiety. The cluster "depressive symptoms" was more evident in the postmenopausal period with respect to the premenopausal one. CONCLUSION: The cluster "depressive symptoms" is significantly different in the premenopausal group with respect to the postmenopausal group, with greater levels of symptomatology in the postmenopausal group. On the contrary, the factor "depressed mood with anxiety symptoms" is present to the same extent in the pre-, peri- and postmenopausal groups. Prior depression is the most predictive variable of subsequent depression in postmenopausal women. Factors related to more pronounced depressive symptoms are number of life events, postmenopausal status, place of residence in rural areas and lower cultural level. 相似文献
19.
Kim DS Park YG Choi JH Im SH Jung KJ Cha YA Jung CO Yoon YH 《Yonsei medical journal》2011,52(6):977-981
Purpose
To investigate the effects of music therapy on depressive mood and anxiety in post-stroke patients and evaluate satisfaction levels of patients and caregivers.Materials and Methods
Eighteen post-stroke patients, within six months of onset and mini mental status examination score of over 20, participated in this study. Patients were divided into music and control groups. The experimental group participated in the music therapy program for four weeks. Psychological status was evaluated with the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) before and after music therapy. Satisfaction with music therapy was evaluated by a questionnaire.Results
BAI and BDI scores showed a greater decrease in the music group than the control group after music therapy, but only the decrease of BDI scores were statistically significant (p=0.048). Music therapy satisfaction in patients and caregivers was affirmative.Conclusion
Music therapy has a positive effect on mood in post-stroke patients and may be beneficial for mood improvement with stroke. These results are encouraging, but further studies are needed in this field. 相似文献20.
Although estrogen replacement therapy (ERT) alleviates depressed moods in postmenopausal women, it is not known whether ERT is equally effective in reducing affective and somatic depressive complaints. One of the authors' goals in this study was to examine possible differences between women receiving and not receiving ERT. The authors studied a group of postmenopausal women. Somatic symptoms in the ERT group were significantly lower than in the Non-ERT group. Affective scores were only marginally lower in the ERT group (p = .06). After controlling for affective depression, the advantage of ERT remained significant with respect to somatic levels, but control for somatic levels essentially eliminated the effects of ERT on affective depression values. Second, in response to orthostatic challenge, the change in systolic blood pressure was significantly smaller in the ERT group. Apparently ERT is associated with more effective blood pressure regulation. Thus there are several potential benefits of ERT, despite recent evidence finding several untoward effects of long-term treatment. 相似文献