Solvent-controlled synthesis of multicolor photoluminescent carbon dots for bioimaging

Multicolor fluorescent carbon dots (CDs) have potential applications in multichannel detection and multicolor imaging. In this study, multicolor fluorescent CDs were synthesized by changing the solvent type and adjusting the reactant ratio. The four prepared CDs emitted bright and stable blue (B-), green (G-), yellow (Y-), and red (R-) fluorescence under a single UV light (λ_ex = 365 nm). The photoluminescence (PL) emission wavelengths changed from 445 nm for B-CDs to 620 nm for R-CDs, and therefore covered the entire visible spectrum. The absolute quantum yields for the B-, G-, Y-, and R-CDs were 27.3%, 31.1%, 22.9%, and 8.8%, respectively. Characterization of the CDs showed that the differences among the optical features of the four prepared CDs arise from the differences among the surface states and nitrogen-derived structures in the carbon core. The four prepared CDs all showed low toxicity and steady PL, and therefore have potential applications in both in vitro and in vivo imaging.

The synthesis and bioimaging of multicolor carbon dots from citric acid and urea.     

Novel synthesis of fibronectin derived photoluminescent carbon dots for bioimaging applications

Fibronectin (FN) derived from human plasma has been used for the first time as the carbon precursor in the top-down, microwave-assisted hydrothermal synthesis of nitrogen doped carbon dots (CDs). FN is a large glycoprotein primarily known for its roles in cell adhesion and cell growth. Due to these properties FN can be over expressed in the extracellular matrix (ECM) of some cancers allowing FN to be used as an indicator for the detection of cancerous cells over non-cancerous cells. These FN derived CDs display violet photoluminescence with UV excitation and appear to possess similar functional groups on their surface to their carbon precursor (–COOH and –NH₂). This is believed to be due to the self-passivation of the CDs'' nitrogen-containing surface functional groups during the heating process. These CDs were then used to stain MCF-7 and MDA-231 breast cancer cells and were observed to interact primarily with the cell membrane rather than intercalating into the cell like the many other types of CDs. This led to the hypothesis that the CDs are selectively binding to the FN overexpressed within the cancer cells'' ECM via amide linkages. This is in agreement with the EDX and FTIR spectra of the FN CDs which indicate the presence of –COOH and nitrogen containing surface groups like –NH₃. The inherent selectivity of the CDs combined with their ability to photoluminesce enables their use as a fluorophore for bioimaging applications.

Fibronectin (FN) derived from human plasma has been used for the first time as the carbon precursor in the top-down, microwave-assisted hydrothermal synthesis of nitrogen doped carbon dots (CDs).     

Correction: Solvent-controlled synthesis of multicolor photoluminescent carbon dots for bioimaging

Correction for ‘Solvent-controlled synthesis of multicolor photoluminescent carbon dots for bioimaging’ by Yang Yan et al., RSC Adv., 2019, 9, 24057–24065.

The authors regret that the contributions of the authors were not correctly indicated in the original article. Yang Yan should be designated as the sole first author, and therefore the footnote stating “The two authors contributed equally” was in error. The correct author list is as shown above.The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.     

Environmentally friendly domino multicomponent strategy for the synthesis of pyrroloquinolinone hybrid heterocycles

An efficient and elegant assembly of pyrene/aryl fused pyrrolo[2,3-b]quinolinone and pyrrolizino[3,2-b]quinolinone hybrid heterocycles was achieved via a domino multicomponent reaction strategy using a solid state melt reaction (SSMR) condition. The 1,3-dipole component was generated in situ from N-methylgylcine/l-proline and isatin, while the Baylis–Hillman adduct prepared from pyrene-1-carbaldehyde and various benzaldehydes is used as the dipolarophile. The domino protocol comprises 1,3-dipolar cycloaddition and a consequent double annulation reaction process. The advantages of this cascade protocol include environmentally friendly conditions, the avoidance of toxic organic solvents, simple work-up and good to excellent product yields.

An efficient and elegant assembly of pyrene/aryl fused pyrrolo[2,3-b]quinolinone and pyrrolizino[3,2-b]quinolinone hybrid heterocycles was achieved via a domino multicomponent reaction strategy using a solid state melt reaction (SSMR) condition.     

Hydrothermal synthesis of nitrogen-doped carbon quantum dots from lignin for formaldehyde determination

This work assessed the fabrication of nitrogen-doped CQDs (NCQDs) from alkali lignin (AL) obtained from spruce, representing a green, low-cost biomass generated by the pulp and biorefinery industries. The AL was found to retain its original lignin skeleton and could be used to produce NCQDs with excellent photoluminescence properties by one-pot hydrothermal treatment of AL and m-phenylenediamine. These NCQDs exhibited blue-green fluorescence (FL) with excitation/emission of 390/490 nm under optimal conditions. The NCQDs showed pH and excitation wavelength-dependent FL emission behaviors. On the basis of the exceptional selective response of these NCQDs to specific solvents, we developed a FL probe for the detection of formaldehyde (FA). The FL intensity of NCQDs was found to be directly proportional to the concentration of FA in the range of 0.05 to 2 mM (R² = 0.993), with a detection limit of 4.64 µM (based on 3σ/K). A composite film comprising NCQDs with poly(vinyl alcohol) was found to act as a sensor with a good FL response to FA gas. When exposed to gaseous FA, this film exhibited increased FL intensity and transitioned from blue-green to blue. A mechanism is proposed in which the NCQDs react rapidly with FA to generate Schiff bases that result in enhanced FL emission and the observed blue shift in color.

A hydrothermal method for synthesis of lignin-based N-doped carbon quantum dots (NCQDs) proposes a mechanism for rapid reaction of NCQDs with formaldehyde to generate Schiff bases, which leads to enhanced FL emission and the observed blue shift.     

Performance of metal–organic frameworks for the adsorptive removal of potentially toxic elements in a water system: a critical review

Elevated levels of potentially toxic elements (PTEs) in aqueous environments have drawn attention recently due to their presence and toxicity to living beings. There have been numerous attempts to remove PTEs from aqueous media. The potential of metal–organic frameworks (MOFs) in removing PTEs from aqueous media has been recognized due to their distinctive advantages (e.g., increased removal capability, large surface area, adjustable porosity, and recyclability). Because of the poor stability of MOFs in water, pre and post synthetic modification and functionalization of MOFs have also been developed for water treatment investigations. This review addresses the performance and mechanisms of PTE removal in various modified MOFs in detail. In order to compare the performance of MOFs, here we used partition coefficient (PC) instead of maximum adsorption capacity, which is sensitively influenced by initial loading concentrations. Therefore, the PC of each material was used to evaluate the adsorption performance of different MOFs and to compare with other sorbents. Furthermore, it discusses the scale-up issues and forthcoming pathway for the research and development needs of MOFs for effective PTE removal. This review further elucidates the main removal mechanisms of PTEs by MOFs. Commercial or domestic water treatment systems or water filters can utilize engineered MOFs to treat water by adsorptive removal. However, marketable products have yet to be investigated thoroughly due to limitations of the large-scale synthesis of MOFs.

This review examines the performance of metal–organic frameworks based on partition coefficient data over the classic maximum adsorption capacities.     

A simple and green synthesis of carbon quantum dots from coke for white light-emitting devices

Coke is a by-product of coal. This paper reports a simple and green chemical oxidation method for carbon quantum dots (CQDs) from coke for use in novel applications. The CQDs emit blue fluorescence and have a fluorescence quantum yield of 9.2% and blue-green-red spectral composition of 48%. A light-emitting diode (LED) was fabricated by combining the CQDs as a white-light converter with an ultraviolet chip. The Commission Internationale de L''Eclairage chromaticity coordinate (0.31, 0.35) and correlated color temperature (5125 K) of the LED are located in a cool white light zone, suggesting that they have superior potential application in lighting devices.

CQDs are prepared from coke. The coke-based CQDs as a converter are applied to the white light illumination field.     

Low-cost and environmentally friendly synthesis of an Al3+ and Mn4+ co-doped Li4Ti5O12 composite with carbon quantum dots as an anode for lithium-ion batteries

To increase the specific capacity and conductivity of lithium titanate (LTO), low-cost and environmentally friendly carbon quantum dots (CQDs) were used to composite with Al³⁺ and Mn⁴⁺ co-doped Li₄Ti₅O₁₂ (LTO-Al/Mn) to improve its electrical properties. The Al³⁺ and Mn⁴⁺ were successfully substituted for Ti located at (16d) sites in the LTO and the CQDs formed a composite with LTO-Al/Mn. The specific capacity of the first cycle at 0.1C increased to 296.5 mA h g⁻¹, and the impedance decreased to 16.8 Ω. The specific capacity maintained 236.0 mA h g⁻¹ after 100 cycles.

To increase the specific capacity and conductivity of lithium titanate, low-cost and environmentally friendly carbon quantum dots (CQDs) were used to composite with Al³⁺ and Mn⁴⁺ co-doped Li₄Ti₅O₁₂ (LTO-Al/Mn) to improve its electrical properties.     

Sustainable synthesis of nanoporous carbons from agricultural waste and their application for solid-phase microextraction of chlorinated organic pollutants

To guarantee the safety of water resources for humans, there is a high demand for the development of highly-efficient probes for solid-phase microextraction and analysis of trace organic pollutants. In this work, we greenly synthesized nanoporous carbons (NPCs) from oilseed rape straw via a facile hydrothermal treatment and potassium bicarbonate activation. Results showed that the NPCs had partly graphitic, amorphous-like structures with a high surface area (up to 1253 m² g⁻¹), large pore volume (up to 0.71 cm³ g⁻¹), high mesopore to total pore volume ratio (up to 29%) and great thermal stability (>400 °C). When the NPCs were utilized as a solid-phase microextraction fiber coating, the extraction efficiencies for chlorinated organic pollutants (COPs) were higher (1–38 times) than with a common commercial polydimethylsiloxane coating because of high surface adsorption energy, strong π–π stacking interactions and large mass transfer capacity. Using the most efficient NPC-8 coating, under optimum extraction conditions (desorption temperature, 290 °C; extraction temperature, 80 °C; extraction time, 25 min), an analysis method for trace COPs in water was developed with good linearity (0.9991–0.9998), high sensitivity (limits of detections, 0.08–0.64 ng L⁻¹), acceptable repeatability (RSDs of single fiber, 2.63–6.73%) and great reproducibility (RSDs of fiber-to-fiber, 2.22–7.12%). Finally, the NPC-8 coating was applied to a real environmental sample with satisfactory recoveries (86.66–103.27%).

Nanoporous carbons were synthesized with green process of oilseed rape straw and applied as efficient adsorbent for microextraction of COPs.     

Facile synthesis of N,P-doped carbon dots from maize starch via a solvothermal approach for the highly sensitive detection of Fe3+

Nitrogen/phosphorus-doped carbon dots (N, P-CDs) with a quantum yield as high as 76.5% were synthesized by carbonizing maize starch via a facile ethanol solvothermal approach. Transmission electron microscopy (TEM) measurement shows that the as-prepared N, P-CDs displayed a quasi-spherical shape with a mean size of ca. 2.5 nm. Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy disclosed the presence of –OH, –NH₂, –COOH, and –CO functional groups over the surface of N, P-CDs. On the basis of excellent fluorescent properties with strong blue fluorescence emission at 445 nm upon excitation at 340 nm, these N, P-CDs were adopted as a fluorescent probe towards the effective detection of Fe³⁺ ions in water. The limit of detection (LOD) was as low as 0.1 μmol L⁻¹ and showed a better linear relationship in the range of 0.1 ∼ 50 μmol L⁻¹. In conclusion, these synthesized N, P-CDs can be efficiently used as a promising candidate for the detection of Fe³⁺ ions in some practical samples.

Nitrogen/phosphorus-doped carbon dots (N, P-CDs) with a quantum yield as high as 76.5% were synthesized by carbonizing maize starch via a facile ethanol solvothermal approach and utilized for the detection of Fe³⁺.     

Green sonochemistry assisted synthesis of hollow magnetic and photoluminescent MgFe2O4–carbon dot nanocomposite as a sensor for toxic Ni(ii), Cd(ii) and Hg(ii) ions and bacteria

The purpose of this study was synthesis of photoluminescent nanoparticles for detection of toxic metal ions. Also, these controllable magnetic nanocomposites were used for detection of Pseudomonas aeruginosa bacteria. Carbon nano-templates were formed by calcination and sonication of lemon extract as a bio-compatible precursor. Then MgFe₂O₄ nanoparticles were incorporated on the carbon nano-templates. The composite was calcinated to decompose carbon and obtain hollow structures. Finally, photoluminescent carbon dots were deposited on the porous magnesium ferrite core. Because of the hollow structure, carbon dots can diffuse to the Mg-ferrite core so magnetic and photoluminescence properties are available simultaneously. Photoluminescence intensity decreases with increasing Ni(ii), Cd(ii), Hg(ii) metal ions and Pseudomonas aeruginosa. Results show an effective nanostructure for identification of toxic metal ions and also bacteria.

The purpose of this study is synthesis of magnetic and photoluminescence nanoparticles at the same time for finding of bacteria that could be fatal and its detection are crucial for some illness prohibition.     

The synthesis of nanofiber membranes from acrylonitrile butadiene styrene (ABS) waste using electrospinning for use as air filtration media

Acrylonitrile butadiene styrene (ABS) waste has been successfully recycled into nanofiber membranes by an electrospinning method for air filter applications. The ABS precursor solutions were made by dissolving the ABS waste in three different solvents, DMAc, DMF, and THF, with various concentrations of 10, 20, and 30 wt%. The solvent and solution concentrations affected the fiber properties (size and morphology) and membrane properties (wettability, crystallinity, and mechanical). Accordingly, we tested the fabricated membranes using SEM, FTIR, XRD, water contact angle, and tensile strength test measurements. The SEM images depicted three different morphologies, i.e. beads, beaded fibers, and pure fibers. The FTIR spectra showed that the solvents completely evaporated during the electrospinning process. The water contact angle test exhibited the hydrophobic properties of all the membrane samples. The XRD spectra showed the amorphous structures of all the membranes. The tensile strength test showed that the membranes fabricated using DMF and DMAc solvents had the best mechanical properties. Considering the fiber size, wettability, and mechanical properties, the membranes fabricated using DMAc and DMF solvents had the best criteria as air filter media. Filtration tests on the membranes fabricated using DMAc and DMF solvents with various solution concentrations depicted that the beads affected the membrane pressure drop and efficiency. The beads gave more space among the fibers, which facilitated the air flow through the membrane. The beads greatly reduced the pressure drop without an overly reduced membrane filtration efficiency. This led to a high-quality factor of the membranes that demonstrated their applicability as potential air filter media.

Acrylonitrile butadiene styrene (ABS) waste has been successfully recycled into nanofiber membranes by an electrospinning method for air filter applications.     

Green and facile synthesis of water-soluble carbon dots from ethanolic shallot extract for chromium ion sensing in milk,fruit juices,and wastewater samples

Self-functionalized carbon dots (CDs) were prepared from ethanolic shallot extract to obtain a total phenolic precursor. The total phenolic extract was then heated at 180 °C for four hours in an autoclave. Only 1 mg L⁻¹ of CDs had high fluorescence emission at 430 nm after excitation at 340 nm and manifested a high selectivity for Cr(vi) ions. The inter- and intra-day emission stability, pH, ionic strength, solvent effect, Stern–Volmer constant, incubation time, speciation of Cr(iii) and Cr(vi) ions, and ion selectivity of the as-prepared CDs were investigated in detail. The proposed method was validated in 20–100 μM linearity with y = 2.2346x as the set-zero intercept linear equation, 0.9981 as the correlation coefficient, 3.5 μM as the limit of detection (LOD), 11.7 μM as the limit of quantification (LOQ), and 2.78% and 5.29% as the intra-day and inter-day relative standard deviations (RSD), respectively. The recovery of drinking water, milk, soymilk, fruit juices (apple and coconut), tap water, and chromium-coated industrial waste water by the investigated Cr sensor was found to be 78.58–119.69%. Therefore, the proposed Cr(vi) sensor had superior advantages of sensitivity, selectivity, rapidity, and reproducibility.

Self-functionalized carbon dots (CDs) were prepared from ethanolic shallot extract to obtain a total phenolic precursor.     

Green synthesis of surface-passivated carbon dots from the prickly pear cactus as a fluorescent probe for the dual detection of arsenic(iii) and hypochlorite ions from drinking water

Efforts were made to develop a simple new approach for the green synthesis of surface-passivated carbon dots from edible prickly pear cactus fruit as the carbon source by a one-pot hydrothermal route. Glutathione (GSH) was passivated on the surface of the CDs to form a sensor probe, which exhibited excellent optical properties and water solubility. The prepared sensor was successfully characterized by UV-visible spectrophotometry, fluorescence spectrophotometry, Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The simple sensing platform developed by the GSH-CDs was highly sensitive and selective with a “turn-off” fluorescence response for the dual detection of As³⁺ and ClO⁻ ions in drinking water. This sensing system exhibited effective quenching in the presence of As³⁺ and ClO⁻ ions to display the formation of metal complexes and surface interaction with an oxygen functional group. The oxygen-rich GSH-CDs afforded a better selectivity for As³⁺/ClO⁻ ions over other competitive ions. The fluorescence quenching measurement quantified the concentration range as 2–12 nM and 10–90 μM with the lower detection limit of 2.3 nM and 0.016 μM for the detection of As³⁺ and ClO⁻ ions, respectively. Further, we explored the potential applications of this simple, reliable, and cost-effective sensor for the detection of As³⁺/ClO⁻ ions in environmental samples for practical analysis.

Efforts were made to develop a simple new approach for the green synthesis of surface-passivated carbon dots from edible prickly pear cactus fruit as the carbon source by a one-pot hydrothermal route.