下颌骨放射性骨坏死伴颌面部组织坏死的临床治疗

目的：探讨较大范围放射性下颌骨骨坏死伴颊瘘的临床手术治疗及下颌骨、面部软组织缺损的修复方法。方法：5例较大范围放射性下颌骨骨坏死,均存在暴露的坏死骨组织和颊瘘,进行下颌骨部分切除和颊部软组织切除,面部组织缺损同期应用腓骨瓣联合前臂皮瓣进行修复。下颌骨缺损平均长度65mm。结果：手术后移植的骨瓣、皮瓣成活,创口Ⅰ期愈合,面部形态及口腔功能恢复。6～12个月复查骨愈合趋正常,未见新的瘘道形成。结论：下颌骨放射性骨坏死伴面部软组织坏死应积极手术治疗,下颌骨的切除手术应在正常边缘上截骨,彻底清除病变坏死组织,方可达到疾病治愈或防止复发,同时行游离腓骨瓣联合前臂皮瓣整复面部组织缺损,能理想地恢复面部的外形及口腔功能。     

腓骨肌皮复合组织瓣的临床手术解剖研究

了解腓骨肌皮复合组织瓣血供特点,手术实施种植义齿的可行性,为其临床应用提供临床手术解剖 基础。方法对１０例病人切取腓骨肌皮复合组织瓣以供修复下骨及周围软组织,观察腓骨肌皮复合组织瓣的（１）血供特点;（２）手术操作要点;（３）手术并发症;（４）腓骨与种植义齿的关系。     

血管化腓骨肌瓣下颌骨重建中髁突不同处理方法对颞下颌关节功能的影响评价

目的 对髁突采用不同处理方法的血管化腓骨肌瓣下颌骨缺损重建后评价患者的临床及颞下颌关节(TMJ)功能状态.方法 患者41例,其中男性21例,女性20例.41例均为累及下颌升支上部且未超过下颌中线的颌骨良性病损,其中应用腓骨替代髁突法重建24例、游离髁突法重建5例、保留髁突法重建12例.采用Fricton TMJ功能量表评价患者术后的TMJ功能,并进行统计学分析.结果 所有患者均未发生关节强直,术后最大开口度31～53 mm,平均值(42.8±5.7)mm.不同术式患者术后面部外形、进食及语音功能比较,差异无统计学意义(P＞0.05);但患者的TMJ功能指数,即功能障碍指数(dysfunction index,DI)及功能紊乱指数(cramiomandibular index,CMI)间比较,差异有统计学意义(P＜0.01).保留髁突组患者的TMJ功能优于腓骨替代髁突组.结论 保留髁突的血管化腓骨瓣下颌骨重建有助于恢复TMJ功能;以腓骨瓣末端替代髁突进行下颌骨重建时,重建髁突的位置和形态对于TMJ的功能有明显影响.     

游离腓骨肌皮复合组织瓣一期修复下颌骨及软组织缺损

目的寻找一种既能满足下颌骨及软组织复合缺损重建需要，又不影响供区功能的新的修复材料。方法对１０例各种原因所致的下颌骨及周围软组织缺损患者，采用游离腓骨肌皮复合组织瓣进行修复重建。所切取的腓骨平均长度９１ｃｍ，肌皮瓣平均大小为４５ｃｍ×６２ｃｍ。结果术后２周经９９ｍＴｃＯ－４骨扫描等证实，９例（９／１０）骨肌皮瓣成活，患者下颌功能与外形良好，行走无障碍。结论腓骨肌皮复合组织瓣骨量充足，骨质坚硬，腓骨血供具二重性，利于塑形，可以用作下颌骨及软组织缺损的修复。     

游离排骨肌皮复合组织瓣一期修复下颌骨及软组织缺损

寻找一种既能满足下颌骨下软组织复合缺损重建需要，又不影响供区功能的新的修复材料。方法对１０例各种原因所致的下颌骨及周围软组织员虱，采用游离腓骨肌皮复合组织瓣进行修复建建。     

Free fibula flap mandible reconstruction in benign mandibular lesions

The mandible may be affected by a variety of pathological conditions such as ameloblastomas, odontogenic keratocysts, central giant cell granulomas, fibro-osseous lesions, and osteomas. They generally are benign, and conservative treatment can be enough in most of the cases. However, they can be clinically aggressive, and especially ameloblastomas, odontogenic keratocysts, and fibro-osseous lesions are prone to recur. The method of treatment remains a matter of controversy in these cases. The aim of this analysis was to study 100 patients who had been treated for benign mandibular lesions, and to emphasize the importance of free fibula flap in the treatment of such lesions.     

血管化游离腓骨瓣下颌骨缺损重建的供区并发症及功能评价

目的:评价血管化游离腓骨瓣下颌骨重建患者的供区并发症及功能情况.方法:游离腓骨瓣下颌骨重建41例,通过临床检查及Enneking下肢功能量表评价围手术期及术后6月后的供区并发症及功能情况.结果:2例供区出现围手术期感染;术后6月后,所有患者踝关节稳定性良好,2例出现踝关节的背屈运动受限,19例(46.3%)出现指足脚拇趾运动受限;患者下肢功能总体恢复良好.结论:游离腓骨瓣下颌骨重建术后对患者下肢功能影响较轻.     

Free fibula flap for reconstruction of the severely atrophic mandible: a retrospective study

The purpose of this retrospective study was to assess the feasibility of using a free fibula flap (FFF) for reconstruction of the alveolar region of the severely atrophic mandible, by determining bone stability after dental implant insertion and prosthetic rehabilitation in a series of eight female patients aged 36–65 years. Dental implant insertion was performed 3–4 months after reconstruction. Prosthetic loading was performed 3–4 months after implant insertion. The height of the reconstructed mandible after surgery was 21.20 ± 1.87 mm, with an increase of 8.80 ± 1.71 mm from the preoperative height. The height of the FFF immediately after reconstruction was 11.24 ± 1.10 mm; this showed a vertical loss of 0.99 ± 0.52 mm (8.79%) and maintenance of 91.21% of the initial height at a mean 14 months post-reconstruction. Applying the Wical and Swoope formula to estimate the original mandibular body height, it was found that the difference between this calculated height (21.17 ± 3.76 mm) and the reconstructed height (21.20 ± 1.87 mm) was only 0.03 ± 3.17 mm (0.14%). An overall insignificant decrease of 0.46 ± 1.14 cm³ in FFF volume had occurred at 3–4 months after dental implant functional loading, while in two cases an increase in volume was found (1.22 cm³ and 1.71 cm³). The good and stable results obtained show that the FFF may be used to reconstruct the whole mandibular alveolar region, with the best possible outcomes.     

下颌骨放射线骨坏死行节段性截骨及游离瓣重建术后疾病复发

该文旨在评价下颌骨放射线骨坏死（ORN）行下颌骨切除及血管化组织瓣重建术后的效果、并发症及疾病复发率。对1995—2009年间40例下颌骨ORN患者进行回顾分析,患者均有头颈癌放疗史,12例接受同其化疗,骨坏死经保守治疗无效,遂行下颌骨节段性截骨及游离组织瓣重建。男26例,女14例,平均年龄62岁,平均随访17．4个月。     

血管化腓骨重建下颌骨后用腓骨残端游离移植及牙种植的可行性研究

目的: 探讨利用残余腓骨增加下颌骨缺损腓骨重建患者垂直骨高度的临床效果。方法: 选择12例下颌骨缺损血管化腓骨重建后拟行种植牙修复的患者,利用腿部残余腓骨段进行垂直骨增量,同期或延期植入种植体并最终完成牙列修复,对术后骨吸收情况和种植体稳定性、存留率等数据采用SPSS 19.0软件包进行统计分析。结果: 术后6个月,近中骨块和远中骨块的吸收量分别为（0.94±0.18）mm和（0.89±0.15）mm;术后12个月,吸收量分别为（1.16±0.21）mm和（1.07±0.17）mm。种植体植入6个月和12个月后,ISQ值分别为（67.25±6.43）和（71.08±4.89）;边缘骨吸收量在植入术后6个月和12个月分别为（0.65±0.12）mm和（0.76±0.18）mm。术后1年种植体存留率为87.1%。结论: 非血管化腓骨具有可靠的抗吸收能力,在下颌骨缺损重建术后垂直骨高度不足的情况下,可为种植体植入提供充足骨量,并维持长期稳定性和存留率。     

Resorption of fibula bone following mandibular reconstruction for osteoradionecrosis

The free fibular flap is commonly used for mandibular reconstruction because of its length, consistent blood supply, and relative ease of harvest. The bone has been shown to maintain mass over time, which confers a potential advantage over other osseous flaps. We know of no published papers on changes in height of fibular bone in patients treated for osteoradionecrosis (ORN). We measured the change in bony height over time as an indirect measure of bone mass. We identified 17 patients (mean age 65, range 49–80 years) who had had reconstruction with a free fibular flap for mandibular ORN. Of them, 10 had fixation with a reconstruction plate, and serial radiographs were available for inclusion in the study. Three measurements were taken on at least 2 rotational tomograms for each patient. Two observers recorded measurements at 25, 50, and 75% of the distance along the bone. Mean change in fibular height (mm) and percentage change were calculated. The interval between radiographs ranged from 5 months 4 days to 20 months 14 days. There was a reduction in fibular height in 8/10 cases, with a mean reduction of 1.5 mm (range 2.6–0.3), or 11%. Our results show a moderate reduction in fibular height, which is comparable with a previously published series of patients without ORN who had reconstruction with miniplates. The stress shielding effects of reconstruction plates were less evident in our patients than in previously published material.     

外科模板在游离腓骨瓣修复上颌骨缺损术中的应用

目的 探讨外科模板在上颌骨切除同期自体腓骨瓣移植修复术中的作用。方法 7例因上颌骨肿瘤需行上颌骨切除术并同期自体腓骨瓣修复的患者，术前取研究模型，根据拟行的手术范围进行模型外科设计，确定牙槽突缺损范围，并将模型修整成需要重建的理想解剖形态，制作模板。外科医生在术中根据模板对腓骨瓣塑形，并确定腓骨瓣固定的位置。术后取研究模型观测腓骨瓣的就位情况，三维CT评价腓骨与下颌骨的相对位置关系。结果 经过外科模板的术中定位，腓骨瓣与下颌骨达到正常相对位置关系，垂直向间隙适合常规叉齿或种植义齿修复。患者戴用义齿后的咀嚼效率明显提高。结论 外科模板是修复医生和外科医生之间有效的交流载体，为患者术后功能和外形的恢复创造了有利条件。     

Giant neglected desmoplastic ameloblastoma: reconstruction with free fibula flap

The desmoplastic ameloblastoma (DA) is a rare variant of the conventional ameloblastoma. It accounts for only 4% to 13% of all ameloblastomas. In this article, we describe the case of a young child affected by a giant neglected DA of the jaw. Preoperative biopsy demonstrated the extremely rare osteoplastic variant of DA. The patient was submitted to segmental mandibulectomy and immediate reconstruction with a free fibula osseous flap. The postoperative period was uneventful. The patient was very satisfied with the functional and aesthetic results of the procedure. In case of such rare variants of ameloblastoma, it is mandatory to preoperatively recognize them to allow the adequate treatment modality to be provided.     

Free fibula flap in the reconstruction of mandible: a report of six cases

The defects secondary to surgical ablation of the mandible have far reaching consequences. Speech, respiration, mastication, deglutition and cosmesis are severely affected. Restoring these functions is a challenging task. Till the late eighties, myocutaneous flaps were the rule for mandibular reconstruction and free bone was used to restore bony continuity. In spite of the result being predictable the outcome left much to be desired. There was also a fairly regular crop of complications. Acceptable dental rehabilitation was almost non-existent. With the introduction of free flaps as a consequence of the development of the operating microscope, the field of reconstruction was revolutionized.