可视化教学结合传统教学法在颞下颌关节教学中的应用探索

目的：探讨可视化教学结合传统教学法在颞下颌关节课程教学中的效果。方法：选择上海交通大学口腔医学院七年制本科生28人,随机将其分为实验组和对照组。实验组采用可视化教学＋传统教学法,对照组采用传统教学法。采用SPSS14.0软件包对2组的教学效果进行比较。结果：理论考试结果显示,2组平均成绩存在显著差异（P＜0.05）;综合能力考核结果显示,实验组成绩显著高于对照组（P＜0.05）。调查问卷结果显示,可视化教学结合传统教学法更能激发学生的学习兴趣,培养良好的医学思维方式。结论：可视化教学结合传统教学法可显著提高教学效果。     

多学科协作教学模式在颞下颌关节病实践教学中的应用

目的: 探讨多学科协作（multidisciplinary team, MDT）结合案例教学（case-based learning,CBL）在颞下颌关节-颌骨-咬合联合诊治教学中的实践效果。方法: 选择上海交通大学附属第九人民医院口腔外科研究生、规培生及进修生共24名,随机分为实验组和对照组,每组12名。实验组采用MDT+CBL线上线下混合式教学法,对照组采用CBL线上线下教学法。经过3个月的教学活动,通过理论与实践操作考试及问卷调查评价教学效果。采用SPSS 26.0软件包对数据进行统计学分析。结果: 实验组理论知识及操作技能考试成绩均显著高于对照组（P<0.05）;问卷调查结果显示,实验组在学习兴趣、沟通技巧、团队协作、档案管理、病历书写、临床思维能力及文献查阅方面的自我满意度均显著高于对照组（P<0.05）。结论: 在颞下颌关节病实践教学中应用MDT结合CBL线上线下混合式教学法,能提高学习成绩,激发学习兴趣,提高职业素质,增强临床综合能力,从而显著提高教学质量。     

Results of epidemiological examinations of the temporomandibular joint in adolescents and young adults

An epidemiological investigation of the temporomandibular joint in 800 persons was undertaken, including two groups of 400 persons aged 15-18 and 19-22 years. The numbers of boys and girls was about the same. Interview and clinical examination comprised morphological and functional features of the stomatognathic system. The TMJ examination carried out included mandibular movements, pain and sound symptoms. The results of the examinations were noted, counted by electronic methods and statistically analysed. From the material, two groups were selected: without TMJ symptoms (OTMJ group) and with TMJ disorders (TMJ group). TMJ disorders were evident in 67.62% of the examined persons and this was common to both age groups. In groups with TMJ disorders a significant incidence of girls was found. In groups with TMJ disorders the number of statistically significant pathological features in the stomatognathic system increased with age. TMJ disorders appeared in both age groups in various forms, separately or in combination, with different frequency. With reference to the number and kind of symptoms obtained on interview and/or on clinical examination, four degrees of intensity of TMJ disorders have been defined and their incidence discussed.     

Specificity of meal pattern analysis as an animal model of determining temporomandibular joint inflammation/pain

Analyzing feeding behavior, and in particular meal duration, can be used as a biological marker for temporomandibular joint (TMJ) inflammation/pain. The present study determined the specificity of meal duration as a measure of TMJ inflammation/pain in a rodent model. The model was also used to test the efficacy of dexamethasone (DEX) as a treatment for TMJ inflammation/pain that was induced by TMJ injection of complete Freund's adjuvant (CFA). In the first study, anesthetized male Sprague-Dawley rats housed in computerized feeding modules received bilateral intra-articular knee injections of CFA or saline. The next day, CFA-injected rats had significant knee swelling and impaired mobility. Food intake in the CFA-injected group was reduced over the next two days and this was due to reduced meal number with no change in meal size. Notably, meal duration was normal in both the CFA and saline knee-injected groups. In the second study, male rats were assigned to one of four groups: Group 1, no CFA and no DEX treatment; Group 2, no CFA and treatment with DEX (0.4 mg/kg i.m. once daily); Group 3, bilateral TMJ CFA injection and no DEX treatment; and Group 4, bilateral TMJ CFA injection and treatment with DEX. CFA significantly increased TMJ swelling and stress-induced chromodacryorrhea in Group 3, but treatment with DEX attenuated these effects in Group 4. Compared to the controls, meal duration was significantly lengthened 24 and 48 h post-CFA injection in Group 3, whereas DEX treatment attenuated TMJ swelling, chromodacryorrhea and normalized meal duration. The data demonstrate that meal pattern analysis, and in particular meal duration, can be used as a non-invasive specific measure of TMJ inflammation/pain and can be used as a marker of DEX treatment efficacy.     

A 6- and 12-month follow-up of appliance therapy in TMD patients: a follow-up of a controlled trial

PURPOSE: This study compared the long-term effects of treatment with a stabilization appliance and treatment with a control appliance in patients with temporomandibular disorders (TMD). MATERIALS AND METHODS: In a controlled trial, 60 TMD patients with temporomandibular joint (TMJ) pain were evaluated after 10 weeks of treatment with either a stabilization appliance or a control appliance. At the 10-week follow-up, the 60 patients were assigned to one of three groups according to their demand for treatment. Group T, the treatment group, comprised 30 patients treated with a stabilization appliance; group C, the control group, comprised nine patients treated with a control appliance; and group M, the mixed treatment group, comprised 21 patients treated with first a control appliance and then a stabilization appliance. Signs and symptoms were evaluated in all three groups at 6- and 12-month follow-ups. RESULTS: At the 6- and 12-month follow-ups, a significant reduction in TMJ pain as measured on a visual analogue scale was found in all three groups, and a significant decrease in signs and symptoms was found in groups T and M. CONCLUSION: After 6 and 12 months of use, the stabilization appliance was found to still be effective in the alleviation of signs and symptoms in patients with TMD. Many patients in group C changed to a stabilization appliance at the 1 0-week follow-up, which significantly reduced the number of patients in this group. Most patients reported positive change in overall subjective symptoms in this trial. The stabilization appliance can therefore be recommended for patients with TMD.     

Arthroscopy of the temporomandibular joint. Examination of 2 patients with suspected disk derangement

2 patients with a history of reciprocal temporomandibular joint (TMJ) clicking were visually examined with arthroscopy of their right side TMJs. Clinical and radiographic examination revealed no signs of arthrosis deformans. One patient with significantly reduced opening ability combined with occasional disappearance of TMJ clicks showed advanced arthrotic changes of cartilage which were not visible radiographically. The other patient with unimpaired function also had a severe arthrotic lesion in the clicking joint. In neither case did the disk appear to be displaced. It is concluded that arthroscopy yields additional information for TMJ diagnosis which cannot be achieved by clinical and radiographic examination alone.     

Oral parafunctions and association with symptoms of temporomandibular disorders in Japanese university students

We examined whether oral parafunctions are associated with symptoms of temporomandibular disorders (TMD) in 3557 Japanese university students, aged between 18 and 26 years. Participants completed a questionnaire regarding various oral parafunctions and subjective symptoms related to TMD, and underwent a dental examination. The prevalence of temporomandibular joint (TMJ) noise, TMJ pain and impaired mouth opening was 41.7, 16.0 and 16.3%, respectively. The most prevalent parafunction was sleeping on one side (60.2%), followed by supporting the jaw by leaning on the palm of the hand (44.8%). Mean age, decayed, missing and filled teeth, and number of teeth were not significantly different between TMD positive and negative groups according to unpaired t-test. The chi-squared test revealed that the ratio of females was significantly higher among students with TMD than without TMD. Multiple logistic regression models adjusted for age and gender demonstrated that chewing on one side caused an increased risk of TMJ noise [odds ratio (OR) = 1.52, P < 0.001], TMJ pain (OR = 1.54, P < 0.001), and impaired mouth opening (OR = 2.00, P < 0.001). Tooth clenching also increased the risk of TMJ noise (OR = 1.86, P < 0.001), TMJ pain (OR = 1.79, P = 0.001) and impaired mouth opening (OR = 1.88, P < 0.001). Further prospective cohort studies, including other potential risk factors, are required to clarify these relationships.     

Hormonal correction in combined therapy of temporomandibular joint dysfunction in women

Pain dysfunction syndrome of the temporomandibular joint (TMJ) in women is often accompanied by mammary and reproductive disorders associated with endocrine disturbances. 30 female patients aged 19-35 years suffering from of the pain dysfunction syndrome TMJ combined with intact dentition and orthognathic occlusion were studied. Dental examination was followed by gynecologic examination. According to the treatment the patients were divided into 2 groups. Group I included women who were administered conventional treatment (orthopedic treatment, drug and physiotherapy). In group II patients conventional therapy was also combined with monophase oral contraceptive "Femoden". Efficacy of treatment in group I was 46.67%; while group II patients showed a 100% favourable effect. Besides, combination of dental and gynecologic therapy was found to exert a 2.1 times more stable clinical effect us compared to conventional treatment. Hormone correction in women with reproductive pathology results in prolonged control of the pain dysfunction syndrome TMJ due to steroid normalization (hypothalamic, hypophysial, ovary steroid normalization) and has no side effects.     

可吸收带线锚固钉与金属锚固钉治疗颞下颌关节盘不可复性前移位的短期疗效比较

目的:研究可吸收带线锚固钉与金属锚固钉应用于颞下颌关节盘锚固术治疗颞下颌关节盘不可复性前移位(anterior disc displacement without reduction,ADDWoR)的短期疗效比较.方法:选取2019年1月—2020年12月于我院行颞下颌关节盘锚固术的40例(52侧)患者,使用钛合金金属...     

Cephalometric keys to internal derangement of temporomandibular joint in women with Class II malocclusions.

The aim of this study was to find cephalometric keys to provide information on the progression of temporomandibular internal derangement. The sample consisted of 58 women with Class II malocclusions. They were examined with routine lateral cephalograms and magnetic resonance imaging of the temporomandibular joint (TMJ) before orthodontic treatment. They were classified into 3 groups according to the results of the magnetic resonance imaging: normal disk position, disk displacement with reduction, and disk displacement without reduction. Thirty-four cephalometric variables regarding their pretreatment lateral cephalograms were analyzed by 1-way analysis of variance to evaluate the differences in the dentofacial morphology among the 3 groups. The results showed a decrease in posterior facial height, a decrease in ramus height, and backward rotation and retruded position of the mandible in the subjects with internal derangement of the TMJ. These changes were less severe in those with disk displacement with reduction and more severe as internal derangement progressed to disk displacement without reduction. The results suggest that internal derangement of the TMJ might induce dentofacial changes, and that some cephalometric variables can assist in identifying potential patients with internal derangement of the TMJ.     

The impact of arthrocentesis with and without hyaluronic acid injection in the prognosis and synovial fluid myeloperoxidase levels of patients with painful symptomatic internal derangement of temporomandibular joint: a randomised controlled clinical trial

We aimed to assess the relationship between myeloperoxidase (MPO) and internal derangement (ID) of temporomandibular joint (TMJ) and effects of arthrocentesis procedure, either alone or in combination with hyaluronic acid (HA) injection on the prognosis of ID of TMJ. A prospective randomised controlled trial has been conducted through patients, who underwent arthrocentesis for the treatment of ID of TMJ, were randomly divided into two groups. Group SS (n = 10) and Group HA (n = 14) patients were assigned 0·9% NaCl solution and sodium hyaluronate intra‐articularly, respectively. Synovial fluid samples were assayed for MPO at the time of arthrocentesis and pain visual analogue scale (VAS) and maximum mouth opening (MMO) scores were recorded at pre‐ and post‐operative periods as well as first‐week, first‐month and third‐month intervals. There was a statistically significant decrease in MPO levels between the first to second arthrocenteses only in Group 2 (P = 0·001). Both VAS scores and MMO measurements decreased in the course of time following arthrocentesis and do not differ between the patients administered HA or SS. Similarly MPO levels do not change significantly between the two groups at either first or second arthrocenteses. In HA group, MPO levels significantly decreased from first to second sessions. In HA group, MPO levels decreased significantly only in patients with clinical success. Arthrocentesis procedure improves both pain VAS and MMO scores in the course of time, but these parameters do not differ between patients receiving either HA or SS. HA significantly reduces levels of MPO in synovial fluid, but SS does not. HA appears to alleviate inflammation inside the TMJ in patients with TMJ‐ID.     

Evaluation of biomechanical properties of Expanded-Polytetrafluoroethylene Soft Tissue Patch after dorsal implantation in the rat to mimic TMJ lateral reconstruction

Clinically, Gore-Tex Expanded-Polytetrafluoroethylene (E-PTFE) has been used to reconstruct the lateral temporomandibular joint (TMJ) ligament. The purpose of this study was to assess changes in the biomechanical properties of implanted E-PTFE over time with respect to tissue infiltration. Ninety-six specimens of implants were divided into four groups. Group A was the experimental group. Thirty-six autoclave-sterilized specimens were subcutaneously implanted into the backs of 36 rats. The rats were randomly sacrificed at 2 (n = 12), 7 (n = 12) and 12 (n = 12) weeks. The implants were tested for mechanical properties including maximal stress, strain and Young's modulus of elasticity (E) using the servo-hydraulic material testing system (MTS). Group B was the in vitro control group. Thirty-six specimens were placed in tissue culture media at 37 degrees C for a time period equivalent to the experimental group to simulate the effect of a moist, warm environment on biomechanical properties. Group C was the temperature and pressure control group. Twelve specimens were autoclave-sterilized to determine the changes of tensile strength under high temperature and pressure. Control group D (no treatment) was tested to determine the initial tensile strength. The results showed significantly larger maximal stress as well as an increase in E and smaller maximal strain in experimental group A than in control groups B, C and D. There was no significant difference among control groups B, C and D. Histological examination of implants at 12 weeks demonstrated that 0.2-0.3 mm of 1-mm thick implants were occupied by connective tissue from each side. It may be concluded that E-PTFE implants become stronger and less flexible after implantation in vivo.     

Patient Self-Report vs. Examiner Assessment of TMJ Symptoms: Stability of Correspondence Rates During Treatment

Questionnaire measures are commonly being used for the assessment of temporomandibular joint (TMJ) symptoms at initial assessment and during TMJ treatment. The usefulness of these measures relies on their correspondence to clinical examination findings, and research has begun to investigate this issue. The present study assessed the correspondence between subjective and objective measures of TMJ dysfunction in 38 patients. These correspondence rates were assessed at initial intake and at six months into treatment. Results showed that correlations between self-report of TMJ symptoms and clinical examination findings were generally high, both at initial assessment and at follow up. Also, patients tend to over-report symptoms when a discrepancy occurs. Results are discussed in terms of their demonstrating support for using self-report measures of TMJ symptoms to help monitor treatment progress.     

The treatment of temporomandibular disorders with stabilizing splints in general dental practice: one-year follow-up

BACKGROUND: The authors evaluated temporomandibular disorder (TMD) outcomes in general dental practice one year after treatment with stabilizing splints (SS) or nonoccluding control splints (CS). METHODS: Seventy-two randomly allocated subjects completed initial treatment. The outcomes measures were a pain visual analog scale (VAS), muscle tenderness, temporomandibular joint (TMJ) tenderness, interincisal opening, TMJ clicks and headaches. After initial treatment, 81 percent of the subjects were found to have been treated satisfactorily. The dentists referred the remaining subjects to a dental hospital. At one year, the authors recalled 52 of the original subjects for evaluation. RESULTS: Improvements after initial treatment were maintained at one year for all outcomes, except for TMJ clicking, which returned to pretreatment levels. Eighty-one percent of the subjects rated their treatment as either good or excellent in reducing jaw pain. The authors found that subjects were aware of more of their TMJ clicks than dentists observed at the one-year clinical examination, but most subjects thought their clicking or the associated pain had been reduced. Fifty-five percent subjects had used their splints in the previous six months, but only 31 percent of these had done so daily. There were no significant differences between splint groups. CONCLUSION: At one year, a good response to TMD treatment in general practice had been maintained, but many subjects still had clicking TMJs. CLINICAL IMPLICATIONS: Trained dentists can manage TMD satisfactorily, with only a small proportion of patients needing specialist attention.     

Topical review: new insights into the pathology and diagnosis of disorders of the temporomandibular joint

The collection of conditions affecting the temporomandibular joint (TMJ) and masticatory muscles, the so-called temporomandibular disorders, can be classified according to the Research Diagnostic Criteria for Temporomandibular Disorders. Of the 3 subgroups--muscle disorders (Group I); disc displacements (Group II); and arthralgia, arthritis, and arthrosis (Group III)--the muscle disorders are most frequently seen in community samples; Group II and Group III diagnoses are less prevalent. This may explain the relative scarcity of studies involving intracapsular TMJ disorders. In this review, new insights into the functional anatomy, imaging, and pathology of disorders of the TMJ are presented. Studies of TMJ dynamics may provide insight into the functional anatomy of the TMJ and thereby into the consequences of Group II and Group III disorders. The clinical use of imaging modalities such as computed tomography and magnetic resonance imaging for the TMJ and related structures remains controversial. Nevertheless, imaging is regularly used in the diagnosis of some Group II and Group III disorders. Magnetic resonance imaging may be of use not only for the visualization of disc displacements but also for the study of bone mineral density of the condyle. Cytokines such as interleukin-1 (IL-1) and tumor necrosis factor alpha (TNFalpha) play an important role in TMJ pathology. For example, IL-1beta, which has been associated with TMJ pain, hyperalgesia, and anterior bite opening, is mostly absent in the synovial fluid of healthy joints. Since both IL-1 and TNFalpha are involved in the development of chronic pain and joint destruction, they may be the targets for specific treatments. While the advances reviewed in this paper are significant, multidisciplinary efforts and formation of international research collaborations will be necessary to continue advancement in the understanding of TMJ pathology and diagnosis.     

The temporomandibular joint in children after breech delivery

In an effort to explain the aetiology of early temporomandibular joint (TMJ) injuries, their incidence in children born by vaginal breech delivery and possible correlation with such deliveries were investigated. The study covered 156 children aged from 4 to 6 years, eighty-three of them born by vaginal breech delivery under application of the classical Mauriceau manoeuvre in seventeen cases and the Bracht manoeuvre in sixty-six. Seventy-three children delivered spontaneously in vertex presentation served as the control group. Signs of TMJ injury were found in 59.6% of the total group, the by-birth percentages being 67.5 in those after breech delivery and 50.7 in those after spontaneous delivery--the difference is statistically significant. The difference was even more significant for the more severe TMJ disorders, their percentages being in two groups respectively 48.2 and 29.7. In the children born by breech delivery the TMJ disorders were invariably attended by severe forms of distocclusion, among which the unilateral form deserves particular attention. The authors conclude that vaginal breech delivery is probably among the factors responsible for early TMJ abnormalities. They call the attention of paediatricians and obstetricians to this fact and urge examination of this joint as a very important part of oral examination in children born by vaginal breech delivery.     

颞下颌关节疾病的外科手术治疗

目的 :颞下颌关节疾病的治疗包括保守治疗和外科手术治疗 ,本研究目的是探讨颞下颌关节疾病外科手术治疗的适应证以及手术方法。方法 :对 1988年至 2 0 0 0年共收治的 76 5例颞下颌关节疾病患者进行回顾性研究。其中颞下颌关节紊乱病患者共 4 18例 ,颞下颌关节外伤 15 9例 ,颞下颌关节强直 131例 ,髁状突肥大 38例 ,颞下颌关节肿瘤 18例 ,颞下颌关节感染 1例 ,其中 6 37例进行了外科手术治疗。结果 :颞下颌关节紊乱病患中 2 18例行颞下颌关节内窥镜术 ,2 1例行颞下颌关节盘复位术 ,91例行颞下颌关节盘修补术 ,11例行陈旧性关节脱位开放复位术 ;131例行颞下颌关节成形术 ;10 9例行髁状突骨折开放复位术 ;38例行髁状突截骨术和正颌手术 ;18例行颞下颌关节肿瘤切除术。结论 :颞下颌关节紊乱病、损伤、关节强直、肿瘤、畸形以及其他关节疾病的手术适应证范围在不断地扩大 ,颞下颌关节外科的手术方法也在不断地改良。颞下颌关节外科手术治疗正向着微创和恢复关节功能的方向发展     

The role of facial trauma as a possible etiologic factor in temporomandibular joint disorder.

PURPOSE: Facial trauma has been suggested as a possible etiologic factor of temporomandibular joint disorder. However, there is little information on the role of macrotrauma. The main purpose of this study was to validate facial trauma as a potential etiologic factor for temporomandibular joint (TMJ) disorder. Multidirectional approaches were applied for the evaluation of the changes of TMJ after TMJ macrotrauma. PATIENTS AND METHODS: Analysis of TMJ status including arthroscopic examination, histomorphologic examination, and synovial fluid biochemical analysis were performed on the patients with mandibular fractures. Additionally, the efficacy of arthrocentesis for the patients of mandibular fracture was evaluated from the functional point of view. RESULTS: In arthroscopic examinations, evidence of synovitis with variable degrees was found. The representative findings are fibrillation and ecchymosis. On histomorphologic examination, bloody smear, degenerated cells and cartilage, inflammatory cells, and crystal were observed. In biochemical analysis, considerable amounts of prostaglandin E(2) and leukotriene B(4) were detected in the synovial fluid of the patients. CONCLUSION: The inflammatory and degenerative changes of TMJ can develop after facial trauma. Trauma can be a possible etiologic factor in cartilage degeneration, and biochemical and intra-articular pathology. Clinicians should recognize the etiologic importance of macrotrauma, and long-term evaluation of the TMJ as well as adequate treatment is required for patients with facial trauma.     

Prevalence, intensity, and correlation of different TMJ symptoms in Lebanese and Italian subpopulations

AIM: The aim of this study was to compare self reported joint related temporomandibular disorder (TMD) symptoms in Lebanese and Italian dental and non-dental students and to detect any correlation between different symptoms. METHODS AND MATERIALS: A questionnaire was distributed in Sardinia (Italy) to dental and psychology students and in Lebanon to dental, physical therapy, and biology students to investigate the prevalence, intensity, and correlation of four temporomandibular joint (TMJ) symptoms. RESULTS: Prevalence of earache varied among the groups from 10.1% to 29.2%, ear stuffiness from 22.5% to 30.8%, TMJ pain from 13.2% to 21.2%, and TMJ sounds from 18.4% to 46.2%. DISCUSSION: Different prevalence and intensity of earache and TMJ sounds were found in the examined sub-populations diverse in cultural background and education. However, prevalence and intensity of ear stuffiness and TMJ pain were similar. Association between TMJ sounds and TMJ pain was detected in selected sub-populations, and correlation between one symptom on one side of the head with the same symptom on the contralateral side were noted suggesting most of these symptoms are bilateral. CONCLUSION: The results of the study might be useful to anticipate the possible occurrence of associated symptoms or the same symptom on both sides of the head. Correlations with cultural background and education are difficult to establish.