苦豆子总硷注射液治疗银屑病30例

苦豆子总硷注射液治疗银屑病３０例石仁琳（兰州医学院附一院皮肤科，７３００００）１９９１年１０月—１９９２年４月采用我院药剂科提供的苦豆子总硷注射液（ＷＦＫ）治疗３０例银屑病观察，效果尚满意，现报告如下：一、治疗方法：苦豆子总硷注射液，ｐＨ５—６，棕黄...     

蛇酶液治疗寻常性银屑病20例

蛇酶液治疗寻常性银屑病２０例马兴武解放军第二六二医院皮肤科（邮政编码１０００８８）临床资料门诊１７例，住院３例。男１４例，女６例。年龄２０～３０岁１０例，３０～４０岁７例，４０岁以上３例。病程６个月以内３例，２～４年１２例，４年以上者５例。点滴状１１...     

应用迪银片治疗银屑病疗效观察

我们从１９９６年７月～１２月采用重庆华邦制药有限公司研制的迪银片治疗银屑病２０例，同时选用复方青黛丸内服做为对照，现将结果报告如下。临床资料３８例均为我院门诊病人，治疗组２０例，男９例，女１１例，年龄１０～６０岁，平均２８岁，病程３天～３０年，其中寻...     

20例寻常型银屑病患者红细胞指数的测定

２０例寻常型银屑病患者红细胞指数的测定蒋建华①刘锦莲①石得仁①一般资料：寻常型银屑病２０例，均为我科住院患者，其中男１２例，女８例。汉族１１例，少数民族９例。年龄１７岁～７１岁，平均３９．７５岁。病程１周～３０年。另选条件相同的健康志愿者２０例做对照...     

中草药熏洗加UV－N光治疗寻常性银屑病44例

中草药熏洗加ＵＶ－Ｎ光治疗寻常性银屑病４４例颜世明，蒲立新辽宁省阜新铁路医院皮肤科（邮政编码１２３００３）４４例病人均确诊为寻常性银屑病。男３２例，女１２例；病程３～３０年，皮疹泛发者２４例，局限者２０例，进行期３０例，静止期１４例。治疗方法均用中草...     

迪银片治疗银屑病

迪银片治疗银屑病缪志辉①陈波①从１９９５年３月～１９９７年３月我们用迪银片治疗各种类型银屑病８６例，获得满意疗效，现报告如下。１临床资料８６例银屑病患者中，男８２例，女４例。年龄１６～８０岁，平均４２．８岁。病期４月～２０年，平均３．７年。临床分型：...     

阿昔洛韦注射液治疗30例扁平疣疗效观察

阿昔洛韦注射液治疗３０例扁平疣疗效观察李祥宝于１９９２年７月用阿昔洛韦注射液静脉点滴治疗面部扁平疣３０例，得到满意效果。临床资料：３０例中，男１０例，女２０例；年龄２０～４９岁，以２５至３５岁为最多；病期最短３个月，最长３年，以１～２年的最多。治疗方...     

蜂毒注射液治疗寻常型银屑病

我们自１９９３年开始应用蜂毒注射液（山西省长治市康宝制药厂生产）治疗寻常型银屑病，疗效较满意，现报告如下。一、临床资料寻常型银屑病患者１０５例。其中男６１例，女４４例；年龄１５～６１岁，平均３０．３岁；病程半个月至３０年，平均５．８１年；患者均为泛发...     

紫外线氧透射载体疗法治疗寻常性银屑病疗效观察

紫外线氧透射载体疗法是近年来开展治疗疾病的新技术，我们自１９９５年１０月～１９９７年５月系统观察了该疗法对寻常性银屑病的疗效，现报告如下。一般资料７０例寻常性银屑病进行期患者，男４０例，女３０例，年龄１２～７３岁，病程１５天～４０年。皮损泛发性５４例...     

白癜风与银屑病互为因果？

白癜风与银屑病互为因果？陈丽，郑庸（江西医学院一附院皮肤科，南昌，３３０００６）我科１９７０年９月至今记录完整的８５０例白癜风病例中见到４例同时存有银屑病。现报告于下：例１：熊某，女，２０岁。皮肤白癜风１８年，银屑病９年。四肢、躯干有圆或不整形白斑，...     

New fillers for the new man

ABSTRACT:  Two new collagen-based lidocaine-containing dermal fillers, ArteSense™/ArteFill™ (Artes Medical, San Diego, CA) and Evolence® (Colbar LifeScience Ltd., Herzliya, Israel), have proved to be of particular interest to men, many of whom seek a long-lasting or permanent correction. ArteFill™ has been available in the United States since 2006, and it is expected that Evolence® will reach the American market in 2008. The properties of the two products will be described, and experience based on the administration of many hundreds of syringes of both products by a Canadian dermatologist will be detailed here, with tips and precautions to optimize patient outcomes.     

Outcomes and adverse effects of ablative vs nonablative lasers for skin resurfacing: A systematic review of 1093 patients

It is generally believed that ablative laser therapies result in prolonged healing and greater adverse events when compared with nonablative lasers for skin resurfacing. To evaluate the efficacy of ablative laser use for skin resurfacing and adverse events as a consequence of treatment in comparison to other modalities, a PRISMA‐compliant systematic review (Systematic Review Registration Number: 204016) of twelve electronic databases was conducted for the terms “ablative laser” and “skin resurfacing” from March 2002 until July 2020. Studies included meta‐analyses, randomized control trials, cohort studies, and case reports to facilitate evaluation of the data. All articles were evaluated for bias. The search strategy produced 34 studies. Of 1093 patients included in the studies of interest, adverse events were reported in a total of 106 patients (9.7%). Higher rates of adverse events were described in nonablative therapies (12.2% ± 2.19%, 31 events) when compared with ablative therapy (8.28% ± 2.46%, 81 events). 147 patients (13.4%) reported no side effects, 68 (6.22%) reported expected, transient self‐resolving events, and five (0.046%) presented with hypertrophic scarring. Excluding transient events, ablative lasers had fewer complications overall when compared with nonablative lasers (2.56% ± 2.19% vs 7.48% ± 3.29%). This systematic review suggests ablative laser use for skin resurfacing is a safe and effective modality to treat a range of pathologies from photodamage and acne scars to hidradenitis suppurativa and posttraumatic scarring from basal cell carcinoma excision. Further studies are needed, but these results suggest that ablative lasers are a superior, safe, and effective modality to treat damaged skin.     

Genetic alterations in RAS‐regulated pathway in acral lentiginous melanoma

Studies integrating clinicopathological and genetic features have revealed distinct patterns of genomic aberrations in Melanoma. Distributions of BRAF or NRAS mutations and gains of several oncogenes differ among melanoma subgroups, while 9p21 deletions are found in all melanoma subtypes. In the study, status of genes involved in cell cycle progression and apoptosis was evaluated in a panel of 17 frozen primary acral melanomas. NRAS mutations were found in 17% of the tumors. In contrast, BRAF mutations were not found. Gains of AURKA gene (20q13.3) were detected in 37.5% of samples, gains of CCND1 gene (11q13) or TERT gene (5p15.33) in 31.2% and gains of NRAS gene (1p13.2) in 25%. Alterations in 9p21 were identified in 69% of tumors. Gains of 11q13 and 20q13 were mutually exclusive, and 1p13.2 gain was associated with 5p15.33. Our findings showed that alterations in RAS‐related pathways are present in 87.5% of acral lentiginous melanomas.     

Self‐resolving superficial primary cutaneous mucormycosis in a 7‐week‐old infant

A 7‐week‐old girl, born at 30 weeks' gestational age, presented to clinic for evaluation of a crop of vesicular lesions that were noted after removal of a bandage that had been in place for 4 days. A punch biopsy of the lesion revealed fungal elements that were later identified as Rhizopus spp. The lesion began to self‐resolve, and no further treatment was needed, with full resolution of the lesion by 1 month after presentation. Clinicians should be aware of the variable presentations of mucormycosis and consider fungal infection in the differential diagnosis when evaluating vulnerable patients with skin eruptions.     

Evidence‐based skin care in preterm infants

Most guidelines on neonatal skin care emphasize issues pertaining to healthy, term infants. Few address the complex task of skin barrier maintenance in preterm, very preterm, and extremely preterm infants. Here, we provide an evidence‐based review of the literature on skin care of preterm neonates. Interestingly, the stratum corneum does not fully develop until late in the third trimester, and as such, the barrier function of preterm skin is significantly compromised. Numerous interventions are available to augment the weak skin barrier of neonates. Plastic wraps reduce the incidence of hypothermia while semipermeable and transparent adhesive dressings improve skin quality and decrease the incidence of electrolyte abnormalities. Tub bathing causes less body temperature variability than sponge bathing and can be performed as infrequently as once every four days without increasing bacterial colonization of the skin. Topical emollients, particularly sunflower seed oil, appear to reduce the incidence of skin infections in premature neonates—but only in developing countries. In developed countries, studies indicate that topical petrolatum ointment increases the risk of candidemia and coagulase‐negative Staphylococcus infection in the preterm population, perhaps by creating a milieu similar to occlusive dressings. For preterm infants with catheters, povidone‐iodine and chlorhexidine are comparably effective at preventing catheter colonization. Further studies are necessary to examine the safety and efficacy of various skin care interventions in premature infants with an emphasis placed on subclassifying the patient population. In the interim, it may be beneficial to develop guidelines based on the current body of evidence.     

Occupational allergic contact dermatitis from spices

About 1000 patients were investigated at our clinic during 1991 for occupational skin disease. and 5 had occupational allergic contact dermatitis from spices. The patients were chefs, or kitchen, coffee room, and restaurant workers. All patients had hand (or finger) dermatitis. The causative spices were: garlic, cinnamon, ginger, allspice and clove, The same patients also had allergic patch test reactions to foods: tomato, lettuce and carrot. Paprika elicited a weak allergic patch test reaction in 2 patients. Occupational allergic contact dermatitis from spices is relatively rare, but needs to be taken into consideration in patients who have hand dermatitis, and work with spices and foods, Patch testing with spices as is useful, but testing with dilutions in pet, may be needed to confirm that the patch test reactions are allergic. Patients also need to be prick tested with spices and foods.     

Subfascial endoscopic perforator vein surgery

Chronic venous insufficiency is a tremendous health care problem in western societies. Venous disease can affect any combination of the superficial, deep, and perforator venous systems of the lower extremities. Generally the superficial venous deficits are addressed through sclerotherapy, enovenous ablation, stab phlebectomy, and or stripping. Patients with advanced clinical sequelae (lipodermatosclerosis or ulceration) of CVI should also be evaluated for the presence of incompetent perforating veins. Open surgical approached to the calf perforating veins (ie. Linton procedure) were complicated by significant wound complications and have largely been replaced by the less invasive Subfascial Endoscopic Perforator Surgery (SEPS). The use of SEPS in patients with ulceration has been shown to be safe and to reduce the time that patients will have ulcers during follow-up. This chapter will review the pathophysiology, diagnosis, and treatment of incompetent perforating veins of the legs with particular attention to surgical issues.