单孔胸腔镜肺大疱切除术治疗自发性气胸的手术效果及对炎症应激反应的影响

目的:探讨单孔胸腔镜肺大疱切除术治疗自发性气胸的临床效果及对患者炎症应激反应的影响。方法:选取2015年1月至2017年6月胸腔镜手术治疗的140例单侧自发性气胸患者,分为单孔组(n=60)与两孔组(n=80),对比两组手术相关指标、手术前后患者血清炎症应激反应指标。结果:两组手术时间差异无统计学意义(P0.05);单孔组术中出血量、切口长度、术后引流量、术后引流时间、住院时间、术后24 h疼痛评分均显著低于双孔组(P0.05);术前两组患者血清去甲肾上腺素、皮质醇、血管紧张素Ⅱ、肿瘤坏死因子-ɑ、白细胞介素-1、C反应蛋白水平差异无统计学意义(P0.05);术后第3天、1周,单孔组患者血清去甲肾上腺素、皮质醇、血管紧张素Ⅱ、肿瘤坏死因子-ɑ、白细胞介素-1、C反应蛋白水平均显著低于双孔组(P0.05);两组手术并发症发生率(3.33%vs.5.00%)差异无统计学意义(P0.05)。结论:单孔胸腔镜肺大疱切除术治疗自发性气胸的效果可靠,与双孔胸腔镜手术相比,术后患者疼痛程度、炎症应激反应更轻。     

单孔与三孔电视胸腔镜手术在自发性气胸中的应用效果比较

目的观察单孔与三孔电视胸腔镜手术治疗自发性气胸的临床效果。方法 110例自发性气胸患者,根据治疗方法不同分为对照组与观察组,每组55例,对照组患者接受三孔电视胸腔镜手术治疗,观察组患者接受单孔电视胸腔镜手术治疗。比较两组手术指标、术后疼痛、血清炎症指标、随访气胸复发情况。结果观察组术中出血量、术后引流量少于对照组,观察组术后胸管引流时间、住院时间短于对照组(P0.05)。观察组术后2小时、术后24小时、术后48小时VAS评分均低于对照组(P0.05)。观察组术后1天、术后3天、术后5天CRP、IL-6、TNF-α水平均低于对照组(P0.05)。两组随访6～12个月复发率差异无统计学意义(P0.05)。结论单孔VATS治疗自发性气胸,术中出血量、术后引流量少于三孔VATS治疗,单孔组术后胸管引流时间、住院时间更短,术后疼痛程度更轻,对机体损伤更小。     

单操作孔胸腔镜手术与多操作孔胸腔镜手术切除纵隔肿瘤的临床效果对比

目的分析单操作孔胸腔镜手术切除纵隔肿瘤的临床效果,并与多操作孔胸腔镜手术各项围术期指标进行比较,综合评价其在临床应用的优势与可行性。方法对2015年6月至2018年6月医院收治的行电视胸腔镜手术(Video-Assisted ThoracoscopicSurgery,VATS)切除纵隔肿瘤的80例患者的临床资料进行回顾性分析,其中行单操作孔胸腔镜手术(SP-VATS)的45例患者为单操作孔组,行常规三孔法胸腔镜手术(MP-VATS)的35例患者为多操作孔组,对比两组术中、术后各项指标,以及并发症及复发情况。结果单操作孔组手术时间、术中出血量、术后镇痛时间、疼痛指数评分、住院天数均少于多操作孔组,差异有统计学意义(P0.05);两组胸腔引流时间、手术当天引流量差异无统计学意义(P0.05);单操作孔组和多操作孔组并发症发生率分别为4.44%、5.71%,两组均未见复发病例,两组并发症的发生率、复发率相比差异无统计学意义(P0.05)。结论单操作孔胸腔镜手术切除纵隔肿瘤安全有效,较多操作孔胸腔镜手术更为微创。     

单操作孔电视胸腔镜肺大疱切除术治疗肺大疱自发性气胸的临床价值研究

目的探讨单操作孔电视胸腔镜肺大疱切除术治疗肺大疱自发性气胸的临床应用价值。方法回顾性分析2019-06—2020-06间林州市中医院心胸外科行电视胸腔镜肺大疱切除术的61例肺大疱自发性气胸患者的临床资料。按照操作方式不同分为单操作孔组(31例)和两操作孔组(30例)。比较2组患者的一般资料、手术相关指标及术后并发症发生率。结果 2组患者的一般资料差异无统计学意义(P>0.05)。单操作孔组患者的手术时间、术中出血量,及术后拔管时间、并发症发生率、住院时间和住院费用等指标均优于两操作孔组,差异有统计学意义(P<0.05)。结论采用单操作孔电视胸腔镜肺大疱切除术治疗肺大疱自发性气胸,术中出血量少、术后并发症发生率低、住院时间短,效果显著。     

胸腔镜辅助小切口开胸术和电视胸腔镜手术治疗自发性气胸的比较

目的比较胸腔镜辅助小切口开胸术（VAMT）和电视胸腔镜手术（VATS）治疗自发性气胸的疗效。方法56例按手术方式分为VAMT组（n=34）和VATS组（n=22）。疗效评价指标包括手术时间、术后疼痛评分、术后引流量、住院时间、复发率。结果与VATS组相比，VAMT组手术时间短[（45±12）minvs（80±10）min，t=-11．356，P=0．000）；术后疼痛评分、术后引流量、住院时间和复发率无显著差异（P〉0．05）。结论VAMT和VATS治疗自发性气胸疗效相同，但VAMT比VATS手术时间短。     

电视胸腔镜辅助小切口手术与电视胸腔镜手术治疗自发性气胸的比较分析

目的比较电视胸腔镜辅助小切口手术（VAMT）与电视胸腔镜手术（VATS）治疗自发性气胸的临床疗效及成本。方法回顾性分析2003年1月至2009年5月四川都江堰市人民医院收治的97例自发性气胸患者的临床资料,其中男69例,女28例;年龄17~72岁,平均年龄34.7岁。均为自发性气胸,术前明确有肺大泡89例,于术中证实有肺大泡8例。首次发生自发性气胸19例（19.6%）,第二次发生57例（58.8%）,第三次及以上发生21例（21.6%）。根据手术方式不同将97例患者分为两组,VAMT组（n=54）：行VAMT治疗;VATS组（n=43）：行VATS治疗。结果术后两组无手术死亡,两组手术时间、术中出血量、术后胸腔引流时间、并发症发生和住院时间差异均无统计学意义（P〉0.05）。失访17例（VAMT组11例、VATS组6例）,随访80例（VAMT组43例、VATS组37例）,随访时间3个月~2年。VAMT组自发性气胸复发2例,VATS组复发1例;两组自发性气胸复发率差异无统计学意义（P〉0.05）。VATS组术中使用一次性耗材（8 045.6元vs.738.2元,P=0.002）和总医疗费用（16 977.8元vs.10 005.8元,P=0.047）高于VAMT组。结论采用VAMT治疗自发性气胸患者的医疗费用明显低于VATS,而临床效果差异无统计学意义。     

单操作孔胸腔镜手术治疗小儿纵隔肿瘤效果分析

目的 探讨单操作孔胸腔镜治疗小儿纵隔肿瘤的效果与安全性.方法 回顾性分析郑州大学附属儿童医院普外科2018-01—2021-03行胸腔镜手术治疗的56例纵隔肿瘤患儿的临床资料.分为单操作孔组和全胸腔镜组,各28例.统计术中出血量、手术时间,以及术后引流时间、并发症发生率、住院时间;采用新生儿疼痛评估量表(NIPS)评分...     

单孔胸腔镜治疗自发性气胸

目的：探讨单孔胸腔镜治疗自发性气胸的可行性。方法回顾分析2010年7月～2013年7月114例单孔胸腔镜手术治疗自发性气胸的临床资料,均采用自制可弯曲双关节腔镜专用器械行单孔胸腔镜手术。结果手术均顺利完成,无中转开胸,未增加穿刺孔,无术后大出血等并发症。手术时间（42．4±11．4） min,术后胸管留置时间（1．8±0．4） d,术后住院时间（5．4±3．4）d。术后随访1～36个月,平均20个月,其中76例＞12个月,无切口感染、出血、积液、气胸复发等并发症。结论单孔胸腔镜手术治疗自发性气胸是安全、微创、可行的。     

单孔胸腔镜手术在白发性气胸治疗中的应用

目的探讨单孔电视胸腔镜下治疗原发性自发性气胸的可行性和安全性。方法回顾分析15例自发性气胸的临床资料,全部采用单孔电视胸腔镜手术。结果全组患者术中出血10。50ml,平均15．6ml;胸腔引流管放置1～5d,平均1．8d：术后住院1—6d,平均2．8d。术后6h、24h疼痛指数（VAS）平均为2．2、3．1,无需药物处理。术后随访1～14个月,无复发及其他并发症发生。结论单孔电视胸腔镜手术治疗自发性气胸安全可靠。     

单孔和三孔电视胸腔镜治疗自发性气胸的对比研究

目的 探讨单孔与三孔电视胸腔镜治疗自发性气胸的临床疗效.方法 回顾性分析2012年4月-2013年4月就诊于咸阳市中心医院胸外科诊断为自发性气胸的患者58例,按照随机数字表法将患者随机分配至单孔电视胸腔镜组28例,三孔电视胸腔镜组30例,并用电话随访法进行随访.采用SPSS19.0统计学软件对两组患者的临床指标、并发症发病率及生存资料进行统计学分析.结果 与传统三孔电视胸腔镜手术相比,单孔电视胸腔镜手术具有术后住院时间更短(t=-4.151,P=0.001)、引流持续时间更短(t=-3.436,P=0.001)、切口满意度评分更高(t=-6.141,P=0.001)、术后6h疼痛视觉评分更低(t=-4.942,P=0.006)、术后24 h疼痛视觉评分更低(t=-3.326,P=0.02)及术后胸腔积液的发病率更低(Z=-2.096,P=0.036)的优点,但手术时间长(t=6.369,P=0.000),在其他并发症发病率、总生存时间(x2 =0.001,P=0.979)及中位无疾病进展生存时间(x2=1.797,P=0.180)方面差异无明显统计学意义(P＞0.05).结论 与三孔电视胸腔镜手术相比,单孔电视胸腔镜手术在住院时间短、术后疼痛轻等方面具有一定的优势,但不能明显缩短手术时间和改善患者术后生活质量.     

单操作孔全胸腔镜手术治疗纵隔肿瘤的临床分析

目的研究单操作孔全胸腔镜手术在治疗纵隔肿瘤的临床治疗效果。方法回顾性分析108例我院2012年8月至2016年3月期间收治的纵隔肿瘤患者作为研究对象,其中48例患者采用单操作孔手术为单孔组,另60例患者采用双操作孔手术为双孔组。比较两组患者手术结果及并发症情况。结果两组患者手术时间、置管时间以及住院时间上无差异,P0.05;而单孔组胸腔引流量、出血量以及疼痛程度均优于双孔组,P0.05。单孔组、双孔组并发症发生率分别为6.25%、13.33%,两组无明显差异,P0.05。结论单操作孔全胸腔镜手术治疗纵隔肿瘤安全可行。     

Uniportal vs standard three-port VATS technique for spontaneous pneumothorax: comparison of post-operative pain and residual paraesthesia.

OBJECTIVE: VATS using the conventional three ports is currently the technique of choice for blebectomy/bullectomy for spontaneous pneumothorax. However, the procedure has recently been shown to have neurological complications related to the port sites. Uniportal VATS has recently been proposed as an alternative to conventional three-port VATS. It is anticipated that the single incision will predispose to a lower incidence of neurological complications. METHODS: We report our initial single surgeon experience of uniportal VATS (n = 16) and provide a comparison of post-operative pain and residual paraesthesia to conventional three-port procedures (n = 19) for the same pathology. RESULTS: In both groups, the pneumothorax pathology was principally primary. There was no difference between the groups in terms of age, spirometry, tissue resected, drainage time and inpatient stay. A difference was, however, noted in inpatient pain scores. The uniportal group had a lower median score of 0.4 (visual analogue range 0-4) while the three-port technique reported 0.8 (P = 0.06, Mann-Whitney test). The maximum score trend was similar (1.4 vs. 2.6, respectively, P < 0.001, Mann-Whitney test). Follow-up for uniportal and three-port VATS averaged 9.4+/-6.6 and 32.1+/-9.9 months, respectively. One patient in the three-port group had a pneumothorax recurrence. Three-port VATS also had a higher residual pain score (0.5) compared to uniportal VATS (0.3). Of clinical significance was the incidence of neurological complications. Eighty-six percent of uniportal patients reported no symptoms. The remaining experienced only mild 'numbness' or 'swelling'. However, in the three-port group, only 42% reported no symptoms. A similar number experienced 'numbness'. Two females described sexual dysfunction due to altered breast sensitivity. Seventeen percent (2/12) reported 'pins and needles'. CONCLUSIONS: Uniportal VATS appears to be tolerable, safe and efficient in treating spontaneous pneumothorax in our series. Moreover, post-operative pain and paraesthesia incidence was lower than three-port VATS. Prospective randomised trials are important to evaluate this technique.     

Uniportal VATS wedge pulmonary resections

Since 2000, 15 patients have undergone single port (uniportal) video-assisted thoracic surgery for wedge pulmonary resection either for diagnosis of interstitial lung diseases (10 patients) or for treatment of primary spontaneous pneumothoraces (5 patients). Diagnosis was obtained in all patients and no recurrences of pneumothorax were seen at follow-up. This initial experience shows that, for specific indications, uniportal video-assisted thoracic surgery for wedge pulmonary resections can be safe and effective.     

Is video-assisted thoracic surgery justified at first spontaneous pneumothorax?

OBJECTIVE: The fundamental role of video-assisted thoracic surgery (VATS) in the treatment of spontaneous pneumothorax is generally acknowledged today. This study intends to evaluate whether VATS is justified at the onset of a first spontaneous pneumothorax through analysis of parameters tested on two group of patients treated respectively with pleural drainage and VATS. PATIENTS/METHODS: The study includes 70 patients affected by first spontaneous pneumothorax divided into two groups of 35 patients for the purpose of therapeutic treatment. The first group underwent pleural drainage while the second underwent VATS. Parameters analyzed were as follows: (1) prolonged air leaks (more than 6 days); (2) time required for pleural drainage; (3) time of hospital stay; (4) management costs; (5) recurrences (follow-up at 12 months). RESULTS: Prolonged air leaks occurred in four patients (11.4%) in the first group and two patients (5.7%) in the second; recurrences occurred in eight patients in the first group (22.8%), and only one in the second group (2.8%). Mean time for drainage and hospitalization was, respectively, 9 and 12 days in patients with pleural drainage against 3.9 and 6 days of those using VATS. Average management costs per patients including hospitalization was calculated at $2,750.00 per patient for the first group compared with $1,925.00 for the second group. CONCLUSIONS: The use of VATS at first spontaneous pneumothorax is justified in the interest of both patients and health administrations as demonstrated by the number of recurrences in patients in the first group and economy savings resulting from use of VATS.     

The Feasibility and Advantages of Subxiphoid Uniportal Video-Assisted Thoracoscopic Surgery in Pulmonary Lobectomy

Background

Uniportal video-assisted thoracoscopic surgery (VATS) lobectomy has emerged as a promising and exciting approach for minimally invasive thoracic surgeries. However, nearly all reported uniportal VATS lobectomies are performed via an intercostal route, and chest wall trauma remains an issue. Here, we report the use of a novel uniportal VATS technique involving a subxiphoid route for pulmonary lobectomies.

Methods

We retrospectively analyzed perioperative data for patients who underwent subxiphoid uniportal and traditional three-port VATS lobectomies from January 2016 to January 2017 at our hospital.

Results

During the study period, 37 patients successively underwent subxiphoid uniportal VATS lobectomies, including three synchronous bilateral pulmonectomies; 68 patients underwent traditional three-port VATS. There were no surgical or 30-day postoperative mortalities, and no significant between-group differences were found in the number of retrieved lymph nodes, number of explored nodal stations, blood loss, drainage time, postoperative complications, or length of hospital stay. Operative time was longer in the subxiphoid uniportal VATS group than in the traditional three-port VATS group (P < 0.001). Visual analog scale (VAS) pain scores after surgery were significantly lower in the subxiphoid uniportal VATS group (P < 0.05).

Conclusions

Subxiphoid uniportal VATS lobectomy is a safe and feasible surgical procedure associated with reduced surgical trauma and postoperative pain as well as improved cosmetic results compared with traditional VATS. Moreover, this procedure is better suited for patients receiving synchronous bilateral pulmonectomy. Further long-term follow-up analyses involving more patients are ongoing.

Trial registry number

ClinicalTrials.gov NCT03051438.

     

猪尾巴导管在单孔胸腔镜肺肿瘤手术中应用的有效性评估:基于倾向性评分匹配法的研究

目的评估猪尾巴导管在单孔胸腔镜肺肿瘤手术中应用的有效性。方法回顾性分析2020年1月至12月上海交通大学医学院附属仁济医院东院接受单孔胸腔镜肺肿瘤手术的患者共441例,根据是否放置猪尾巴导管分为胸管组和猪尾巴管组,通过倾向性评分匹配法进行1∶1匹配,对比两组患者围手术期的各项指标。结果匹配后每组143例配对成功,匹配后两组间基线特征无统计学差异。对比两组围手术期指标发现,猪尾巴管组患者术后3天胸腔引流总量显著多于胸管组(375.49 ml对285.03 ml,P<0.001),术后两周复查CT示胸腔积液量显著少于胸管组(131.77 ml对178.84 ml,P=0.032),两组术后疼痛评分、引流天数及住院天数无明显统计学差异。结论加放猪尾巴导管可有效改善单孔胸腔镜肺肿瘤术后胸腔引流情况,且不增加患者术后疼痛,不延长胸腔引流及住院天数。     

VATS与RATS精准解剖的亚肺叶联合切除术的回顾性队列研究

目的:评估机器人辅助亚肺叶联合切除手术的围术期安全性和短期疗效。方法:回顾性收集2015年1月~2020年8月在浙江大学医学院附属第一医院胸外科行亚肺叶联合切除手术的131例早中期非小细胞肺癌(Non-small cell lung cancer,NSCLC)患者的临床资料,并根据手术方式分为机器人辅助胸腔镜手术(Robot-assisted thoracic surgery,RATS)组(20例)和电视胸腔镜辅助手术(Video-assisted thoracic surgery,VATS)组(111例)。根据基线资料对两组患者进行倾向性评分匹配,比较匹配后两组的围手术期结果。结果:倾向性评分匹配后最终纳入RATS组患者18例,VATS组患者56例。RATS组清扫了更多的N1淋巴结站数(P<0.05)和N1淋巴结个数(P<0.05),并且发现了更多的转移阳性的N₂淋巴结(P<0.05)。RATS组的术中出血量和胸腔引流管置放时间略少于VATS组,但差异无统计学意义(P>0.05)。RATS组的住院费用高于VATS组,但差异无统计学意义(P>0.05)。两组在淋巴结升期率、术后住院天数、术后第1d数字评分法疼痛(Numeric rating scales,NRS)评分、围术期并发症、术后辅助治疗方面无统计学差异。结论:机器人亚肺叶联合切除手术具有与胸腔镜手术相似的安全性和短期疗效,但RATS清扫淋巴结更彻底,且可减少术中出血和减少胸腔引流管置放时间。     

Uniportal video-assisted thoracic surgery for primary spontaneous pneumothorax: clinical and economic analysis in comparison to the traditional approach

We aimed to verify the clinical and economic effects of uniportal video-assisted thoracic surgery (VATS) in patients with primary spontaneous pneumothorax (PSP) compared to traditional three-port VATS technique. We analyzed 51 consecutive patients (23 three-port VATS and 28 uni-port VATS), treated by bullectomy and pleural abrasion, to detect differences between the two groups with regard to intraoperative management, postoperative course, pain, paraesthesia and costs. Data about pain and paraesthesia were collected by telephonic interview within a minimum follow-up period of six months. Compared to three-port VATS, patients treated by the uni-port VATS were discharged more quickly (3.8 days vs. 4.9 days, P=0.03) and experienced paraesthesia less frequently (35% vs. 94%, P<0.0001). No difference in chronic pain was observed between the two groups (numeric pain score: 0.6 uni-port vs. 1.3 three-port, P=0.2). Compared to three-port VATS, we found a significant reduction in postoperative costs for the patients operated on by the uni-port technique (euro1407 vs. euro1793, P=0.03), without any increase in surgical costs. In conclusion, uniportal VATS appears to offer better clinical (postoperative stay and rate of paraesthesia) and economic (postoperative costs) results than the standard three-port VATS for treating primary spontaneous pneumothorax.     

单操作孔电视胸腔镜肺叶切除术治疗早期肺癌的临床研究

目的探讨单操作孔电视胸腔镜(single utility port video-assisted thoracic surgery,single utility portVATS)肺叶切除术治疗早期肺癌的临床效果。方法回顾性分析2009年9月至2011年10月解放军总医院胸外科采用单操作孔VATS肺叶切除术治疗162例早期肺癌患者的临床病例资料(单操作孔组),用同期胸腔镜辅助小切口(video-assisted mini-thoracotomy,VAMT)肺叶切除术221例早期肺癌患者做对照(小切口组),比较两组患者的手术时间、术中出血量、淋巴结清扫数、术后下床时间、拔除胸腔引流管时间及术后并发症等。结果两组患者手术过程均顺利,无围手术期死亡。单操作孔组与小切口组患者术中出血量(162.8±75.6)ml vs.(231.4±62.8)ml、术后下床时间(2.2±0.3)d vs.(3.7±0.5)d、拔除胸腔引流管时间(3.5±0.2)d vs.(4.6±0.4)d,差异有统计学意义(P0.05);单操作孔组与小切口组患者的手术时间(133.7±22.0)min vs.(124.9±25.7)min、淋巴结清扫数(11.7±1.9)枚vs.(12.5±2.7)枚、并发症发生率7.4%vs.8.1%,差异无统计学意义(P0.05)。结论单操作孔VATS肺叶切除并淋巴结清扫治疗早期肺癌安全、可靠,较VAMT创伤更小、恢复更快。     

Uniportal VATS for mediastinal nodal diagnosis and staging

The objective of the present study was to assess feasibility of single port (uniportal) VATS in the diagnosis and staging of mediastinal nodal enlargements. To this purpose, between January 2002 and October 2005, 13 patients (8 males and 5 females; mean age 54 years) have undergone uniportal VATS sampling of mediastinal nodes either as part of a diagnostic pathway or as a staging procedure for primary lung cancer when either nodal stations were inaccessible to standard mediastinoscopy or in the event of redo nodal biopsy. Sampled stations were the aortopulmonary window (6), subcarinal (1), right paratracheal (5), and, paraesophageal (1) ones. In all cases, sufficient samples were made available for pathological diagnosis. Postoperatively, neither morbidity nor mortality was observed. The median length of stay in the hospital was 1 day. In conclusion we showed that uniportal VATS can be effectively used to achieve diagnosis and staging of mediastinal nodal stations.