Squamous cell carcinoma of the sinonasal cavities.

Squamous cell carcinoma of the sinonasal cavity is an uncommon neoplasm. The symptoms of this tumor are aspecific, and the diagnosis is often made in an advanced stage of disease. Imaging is necessary for evaluating paranasal extension and possible intracranial spread, orbital involvement, infratemporal extension, spread to the nasopharynx, oropharynx, or oral cavity, and spread along neurovascular bundles or perineural spread. Sinonasal cancers are studied with CT or MRI, and in many cases both modalities are used, as they often offer complementary information. The CT and MRI appearance of this kind of tumor is reviewed in this article.     

Papillomas of the nasal and paranasal cavities.

Intranasal papilloma is an uncommon, benign tumor of the nasal cavity and, by extension, the paranasal sinuses. It occurs only once for every 25 cases of ordinary nasal polyps. A recent case is reported, followed by a summary of the cases treated at the Emory University Hospitals in the last ten years. The histologic classification is reviewed, as well as current treatment, with an emphasis on wide surgical excision through the lateral rhinotomy approach. Because about 10% of these tumors will have associated malignancy, guidelines are given to insure that this malignant transformation is not missed.     

Monitoring nasal conductance by bilateral nasal cannula pressure transducers

Nasal obstruction is common and may disturb well-being during daytime and sleep. Its objective assessment by standard methods requires patient cooperation and inconvenient instrumentation. Therefore, the purpose of this study was to develop a novel, unobtrusive technique for continuous monitoring of changes in nasal conductance during natural breathing based on pressure recordings at the left and right nares. In ten volunteers, pressure swings derived independently from left and right nasal cannula were recorded at baseline, and after topical application of histamine and xylomethazoline. Nasal conductance was measured by means of epipharyngeal pressure recordings and face-mask pneumotachography as the reference standard. Decreases in nasal conductance were associated with changes in relative timing and shape of left and right nasal cannula derived pressure swings during breathing. This was reflected in decreases in the coefficient of cross-correlation between left and right nasal pressure signals. Diagnostic accuracy in detecting a fall in nasal conductance to <80% baseline by the maximal coefficient of determination from cross-correlation of left versus right nasal pressure was evaluated by receiver operator characteristics. The area under the curve was 0.88, 95% confidence interval 0.76 to 0.99, n = 40, P < 0.05 versus 0.5. We conclude that patterns of pressure swings derived from left and right nasal cannula may serve as a noninvasive means to detect changes in nasal conductance without requirement of patient cooperation.     

Contact-tip Nd:YAG laser applications: squamous nasal papillomatosis

Concurrent use of nasal endoscopes and the contact-tip Nd:YAG laser provides the necessary visualization and control for treating a widespread condition such as nasal papillomatosis. This laser should decrease the likelihood of spread to other sites within the patient's upper respiratory tract or to attending health care personnel.     

双鼻腔操作法纤维支气管镜引导气管内支架置入术

目的探讨纤维支气管镜直视引导下定位准确的气管内支架置入方法。方法采用双鼻腔操作法，以纤维支气管镜直视跟踪经另一侧鼻腔送入气管的置入器与支架，引导调整，将支架准确地施放于气管狭窄部位，为11例气管重度狭窄的患者进行了气管内支架置入术。结果11例病人均一次性成功地放置了支架。呼吸困难即刻得到缓解，无1例发生并发症。结论双鼻腔操作法纤维支气管镜引导气管内支架置入术。直视下操作，定位准确，安全简易，避免了支架释放后再调整引发的并发症，亦无需X线定位，是治疗气管狭窄行之有效的方法。     

鼻内镜联合柯陆氏手术治疗鼻腔鼻窦内翻性乳头状瘤

目的 探讨鼻内镜联合柯陆氏手术治疗鼻腔鼻窦内翻性乳头状瘤(NIP)的临床疗效.方法 对24例行鼻内镜联合柯陆氏手术治疗鼻腔鼻窦内翻性乳头状瘤患者资料进行回顾性分析.结果 24例患者中,治愈22例.2例复发.对于复发者再次在内镜下治疗,并对复发部位采用电刀烧灼,无恶变病例出现.结论 鼻内镜联合柯陆氏手术治疗鼻腔鼻窦内翻性乳头瘤是一种安全有效的治疗方法 ,在临床上具有推广价值.     

Arthropod transmission of rabbit papillomatosis

The virus of rabbit papillomatosis, a neoplastic disease studied intensively in relation to cancer because of its tendency toward malignant transformation, has been successfully transmitted by Aedes aegypti, Rhodnius prolixus, and Triatoma infestans from papillomas induced in cottontail rabbits, and by the first species mentioned, from papillomas induced in domestic rabbits. This was accomplished by interrupted feeding, feeding after an interval of several days from the infective meal, or by application of a suspension of the mouthparts of the insects either immediately after their infective meal or several days later. Insect transmission was also successful from the satellite growths resulting from subcutaneous extensions of the typical papillomas of infected cottontails, and from certain peculiar, subcutaneous nodules, arising rapidly after infection, and not heretofore described. Although the latter growths resembled rabbit fibromas, antibodies to fibroma virus could not be demonstrated by neutralization tests with the sera of the animals involved.     

改良Millard法同期鼻畸形整复矫治双侧唇裂46例

目的：探讨双侧唇裂和鼻畸形同期整复的手术要点。方法：随机选取46例双侧唇裂（伴／不伴腭裂）患者，应用改良Millard法进行唇裂整复，术中解剖复位口轮匝肌，重建口轮匝肌环；恢复干湿唇交界线的连续性，重建唇珠形态。同期初步矫正鼻畸形，延长鼻小柱。结果：患儿术后上唇瘢痕近似于人中嵴；唇红缘、干湿唇交界线连续、协调、对称，唇红丰满，上下唇、鼻底宽度协调，鼻小柱延长明显，鼻尖形态满意。结论：改良后Millard法可一期完成双侧唇裂和鼻畸形整复。术中便于同期行鼻畸形早期整复，能有效地初步纠正鼻畸形，手术效果理想     

气管和支气管乳头状瘤临床分析

目的总结气管和支气管乳头状瘤的临床特点及支气管镜下介入治疗情况。方法回顾性分析2012年1月-2018年6月在应急总医院确诊的气管和支气管乳头状瘤的24例患者临床资料,进行分析、总结。16例患者有吸烟史,其中男患者13例;19例良性,5例恶变;9例病变为单发,占37.5%,累及2个及2个以上部位的共15例,占62.5%。喉部受累4例,中央型气道受累21例,二级支气管受累3例。肿瘤可以侵犯多个部位。结果经支气管镜下介入治疗后,气道狭窄程度、气促分级、卡氏评分(KPS)均得到明显改善(P 0.01)。结论气管和支气管乳头状瘤是气道内少见的肿瘤,多为良性病变,可以发生恶变,支气管镜下介入治疗是有效的治疗手段。     

Radiologic features of papillary adenoma and papillomatosis of the biliary tract

Background: The purpose of this study was to describe the imaging findings of papillary adenoma of the bile ducts. Methods: Imaging modalities including sonography, computed tomography, cholangiography, and endoscopic sonography obtained in five patients with papillary adenoma of the bile duct were retrospectively reviewed and correlated with pathologic findings. Results: In four cases, imaging findings were a dilatation of the bile ducts due to a protruding mass within the lumen of the common bile duct. In one case, the biliary tract obstruction was not due to the mass but to mucus secretion that was detected at sonography, endoscopic sonography, and cholangiography. Multiple lesions were observed in two cases at pathology and not detected preoperatively. All the lesions contained foci of in situ carcinoma or mild dysplasia. Conclusion: Imaging is useful in detecting bile duct tumors. Hypersecretion of mucus is rare but highly characteristic of bile duct adenoma. Received: 6 July 1995/Accepted: 18 August 1995     

Squamous papilloma of the esophagus.

We have described two cases of squamous papilloma of the esophagus, one of which is an unusual case of probable malignant transformation of a benign squamous papilloma to a low-grade verrucous carcinoma.     

胆管黏液性乳头状腺瘤1例

病例女,66岁,反复发作右上腹痛2个月入院,为绞痛伴后腰背部放散痛,进油腻食物可诱发。体格检查：皮肤、巩膜轻度黄染,余无特殊体征。化验结果：ALT 174U/L,AST106U/L,Tbil 156.4umol/L,Dbil 120.6umol/L。彩超见肝内外胆管扩张,伴结石影,胆总管内絮状回声。     

肝内胆管乳头状瘤的CT及MR表现

目的：探讨肝内胆管乳头状瘤（Intrahepatic biliary papillomatosis,IHBP）的临床病理特征、影像学表现。方法 ：回顾性分析5例经手术病理证实的IHBP患者的临床病理特征及影像学表现,并结合文献进行分析和讨论。结果：5例IHBP患者中2例表现为间歇性黄疸、1例腹痛伴发热、1例左腰背部酸痛,1例体检时发现。影像学特点：5例均发现全胆管树系统扩张,胆总管下段无明确占位或结石,受累肝内胆管相对比另一肝叶胆管或胆总管不成比例的扩张,受累肝内胆管呈＂瘤样＂扩张,扩张的肝内胆管出现乳头状或长条状肿块影,MRCP示扩张胆管内多发乳头状及条状充盈缺损,3例位于右肝内胆管、2例位于左肝内胆管,肿块直径约0.3~2.5 cm,于CT平扫呈等或稍低密度,MR T1WI表现为等或稍低信号,T2WI上多呈等高信号,DWI上呈乳头状及条状高信号,增强扫描肿块呈轻度强化。结论：IHBP的影像学表现有一定的特征性,尤其MRCP、DWI及动态增强检查,熟悉该病的特征性影像学表现有助于对IHBP诊断及鉴别诊断。