Comparative analysis of progesterone and estradiol reception in human myoma

Cytosolic and plasma membrane receptors for progesterone and estradiol are studied in myomatous nodes (MN) and in histologically unaltered myometrium (HUM) against the background of myoma. The level of cytosolic receptors for both hormones is higher in the myoma cells than in the essentially healthy myometrium. In the plasma membranes the progresterone reception is reduced and the estradiol reception is unchanged compared with HUM. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N ^o 7, pp. 33–34, July, 1994     

Impact of 8-isoestrone analogs on estradiol binding in uterine tissue from ovariectomized rats

8-Isoanalogs of estrone were studied for their ability to influence estradiol binding in the cytosolic fraction of uterine tissue from ovariectomized rats and for their uterotropic activity 24 h after injection into such rats. Two groups of estrone 8-isoanalogs with opposite biological effects were identified: those increasing estradiol binding in the cytosolic fraction of uterine tissue and those decreasing this binding. Uterogenic activity was exhibited by all of the compounds tested, with the exception of compound I. No correlation was found between the uterogenic activity of the isoanalogs and hormone-receptor interactions. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, N ^o 2, pp. 165–167, February, 1995     

Contribution of the reproductive hormones to the regulation of prostaglandin F2α production by immunocompetent cells

The ability of estradiol, progesterone, and chorionic gonadotropin to influence prostaglandin F_2α production by intact splenocytes of CBA mice was studied. Estradiol and progesterone similarly activated the processes of prostaglandin F_2α production. No relationship was revealed between the effect and the concentration of the hormones. Chorionic gonadotropin activated prostaglandin production by immunocompetent cells but only when used in a concentration reflecting the peak of its physiological secretion. Combining gonadotropin with estradiol or progesterone did not lead to any appreciable differences in the prostaglandin-stimulating action of each hormone alone. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 120, N ^o 8, pp. 178–180, August, 1995 Presented by K. P. Kashkin, Member of the Russian Academy of Medical Sciences     

Effects of some steroid hormones on Ca2+ transport and oxidative metabolism of isolated mitochondria

Effects of prednisolone, estradiol, and testosterone on the transport of Ca²⁺ and the respiration induced by it in the heart and liver mitochondria of rats were studied. Prednisolone and testosterone were found to reduce the Ca-accumulating capacity of the mitochondria, the rates of ion entry and exit, and the rate of Ca²⁺-induced respiration. Estradiol, while inhibiting Ca²⁺ transport across mitochondrial membrane, did not influence the respiration in the phase of Ca²⁺ absorption, but accelerated it in the phase of ion exit. These data suggest that due to their lipophilic properties, the steroids become incorporated in the mitochondrial membrane, thereby changing its viscosity and permeability and limiting the mobility of transmitter proteins. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, N ^o 12, pp. 616–618, December, 1994     

Involvement of opioid receptors in the production of nonspecific protective responses

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N ^o 10, pp. 381–384, October, 1993     

Morphological characteristics of the brain in 20–21-day-old rat embryos and in 1–5-day-old rats

Translated fromByulleten' Experimental'noi Biologii i Meditsiny, Vol. 116, N ^o 12, pp. 641–642, December, 1993     

Experimental model of depletion of the blood kallikrein-kinin systems

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N ^o 10, pp. 343–344, October, 1993     

Effect of 3-orthocresylphosphate on the toxicity of GABA-lytics for mice

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N ^o 10, pp. 396–397, October, 1993     

Relationships between catecholamine levels in the salivary glands,oral mucosa,and saliva of rats with experimental staphylococcal sialadenitis

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N ^o 7, pp. 38–40, July, 1993.     

Glucocorticoid interaction with bone marrow lymphoblast receptors in acute leukemia

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 115, N ^o 4, pp. 164–165, February, 1993.     

Adaptation to periodic hypoxia restricts subdural hemorrhage during audiogenic epileptic seizures in rats

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N ^o 12, pp. 572–574, December, 1993     

Expression of activation markers on decidual lymphocytes during the first trimester of pregnancy

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116 N ^o 10, pp. 414–416, October 1993     

Effect of amiridine and tacrine on potassium currents in the nerve fiber

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N ^o 10, pp. 397–400, October, 1993     

Paradoxical effect of lymphocytes during filtration of platelet-rich heparin-treated plasma

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N ^o 11, pp. 502–503, November, 1993     

Responsiveness of mesenteric arterioles to epinephrine in metabolic coma

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N ^o 12, pp. 577–579, December, 1993     

Pathways of the realization of immunomodulating effects of neurotransmitters

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 115, N ^o 4, pp. 401–404, April, 1993     

Effect of immune “sessile” receptors on the choline receptors of the lymphocyte membrane in mice immunized with certain antigens

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 115, N ^o 2, pp. 384–386, April, 1993     

Effect of met-enkephalin on sinus arrhythmia caused by burst stimulation of the vagus nerve

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 116, N ^o 7, pp. 4–6, July, 1993     

Evaluation of the antipyretic effect of psychotropic agents and their influence on the fever-lowering effect of acupuncture

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 115, N ⁰ 3, pp. 262–264, March, 1993     

Glucocorticoid-dependent regulation of the expression of high-density lipoprotein binding sites in rat hepatocytes

It is shown that dexamethasone increases the number of HDL binding sites in cultured hepatocytes bothin vivo andin vitro. The glucocorticoid acts in a dose-dependent and reversible manner within a wide range of concentrations, including physiological and subphysiological doses. Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, N ^o 1, pp. 47–50, January, 1994