脉压与急性冠脉综合征的相关性研究

目的探讨急性冠脉综合征(ACS)病人中脉压(PP)水平与冠心病危险因素和冠状动脉病变程度的相关性.方法将149例ACS病人分为PP<65 mmHg组(41例)和PP≥65 mmHg组(108例),分析两组病人年龄、性别、高血压、高脂血症、糖尿病、吸烟等冠心病危险因素以及冠状动脉病变程度.结果①PP≥65 mmHg组病人的危险因素明显多于PP＜65 mmHg组(P＜0.05),其中2个以上危险因素的病人在PP≥65 mmHg组中高达96.3%(P＜0.01);②PP≥65 mmHg组病人冠状动脉3支血管病变的患病率显著增高(P＜0.05).结论发生ACS时,PP高的ACS病人其危险因素多于PP低者,且冠状动脉病变亦较为严重.     

脉压与急性冠脉综合征患者冠脉病变的关系

目的　探讨急性冠脉综合征 (ACS)患者中脉压 (PP)水平与冠心病危险因素和冠状动脉狭窄程度的相关性。方法　将 74例ACS患者分为PP <65mmHg组 ( 2 0例 )和PP≥ 65mmHg组 ( 5 4例 )。分析 2组中年龄、性别、高血压、高脂血症、糖尿病、吸烟等冠心病危险因素以及冠脉血管狭窄程度。结果　 ( 1)PP≥ 65mmHg组患者的危险因素明显多于PP <65mmHg组 (P <0 .0 5 ) ,其中≥ 2个危险因素的患者在PP≥ 65mmHg组中高达 96.3 %(P <0 .0 1) ;( 2 )PP≥ 65mmHg组冠脉狭窄程度与PP <65mmHg组比较差异无显著性。 结论　发生ACS时 ,PP大的ACS患者其危险因素多于PP小者 ;PP与相关冠脉狭窄严重程度不相关     

老年高血压病病人脉压与冠心病发病率分析

目的研究老年高血压病病人不同脉压(PP)时冠心病发病率的变化。方法回顾性分析120例老年高血压病病人的PP,并分析PP与冠心病发病率的关系。结果PP<50mmHg组,50mmHg≤PP<80mmHg组,PP≥80mmHg组间经方差分析,收缩压、舒张压之间有统计学意义(P<0.05或P<0.01);而平均动脉压无统计学意义(P>0.05)。随着PP值增大,收缩压逐渐增大,舒张压逐渐降低。3组间随着PP值的增大,冠心病的发病率随之增加(P<0.01)。结论在老年高血压病病人中,随着PP的增大,冠心病的发病率呈增加趋势。     

高血压患者脉压与冠状动脉狭窄程度

目的探讨高血压患者脉压(PP)与冠状动脉狭窄的关系。方法279例高血压(EH)患者均行冠状动脉造影及冠状动脉狭窄积分,进行统计学分析。结果显示PP≥60mmHg组的冠脉狭窄积分、冠脉狭窄率高于PP<60mmHg组(P<0.001)。分析冠心病的危险因素时,PP具有统计学意义(P<0.05)。结论PP增大是冠心病的独立危险因素,使冠状动脉的狭窄率、狭窄程度、累及的血管支数增加。     

高血压患者脉压与冠状动脉狭窄程度

目的探讨高血压患者脉压(PP)与冠状动脉狭窄的关系.方法 279 例高血压(EH)患者均行冠状动脉造影及冠状动脉狭窄积分,进行统计学分析.结果显示PP≥60 mm Hg组的冠脉狭窄积分、冠脉狭窄率高于PP<60 mm Hg组( P<0.001).分析冠心病的危险因素时,PP具有统计学意义( P<0.05).结论 PP增大是冠心病的独立危险因素,使冠状动脉的狭窄率、狭窄程度、累及的血管支数增加.     

高血压患者脉压对尿微量白蛋白的影响

目的探讨高血压患者脉压变化对尿微量白蛋白(UmALB)排泌量的影响。方法选取160例原发性高血压患者,根据脉压(PP)水平分成PP<70mmHg组,77例和PP≥70mmHg组,83例,两组均行系统降压治疗1月,将血压达标(BP140/90mmHg)者再继续治疗观察5月,分析这些患者治疗前后PP及UmALB的变化,并进行比较。结果PP<70mmHg组治疗前后UmALB量无明显改变。PP≥70mmHg组治疗后有60例血压达标,该组总的UmALB分泌量减少,其中治疗后PP<70mmHg病例比治疗后PP≥70mmHg病例的UmALB分泌量明显减少(P<0.05)。结论高血压患者随着脉压变化可引起UmALB排泌量的变化,PP从≥70mmHg降至PP<70mmHg时UmALB排泌量显著下降。     

动态脉压与老年高血压合并冠心病及颈动脉硬化的关系

目的研究老年高血压患者动态脉压(PP)与冠心病并发症及颈动脉粥样硬化的关系,为临床有针对性的干预PP、预防高血压并发症提供理论基础。方法对老年高血压及老年高血压合并冠心病的动态PP进行比较,同时对老年高血压颈动脉内膜中层厚度(IMT)增厚组与正常组的动态PP进行比较。结果(1)与单纯高血压组比较,高血压合并冠心病组的24h动态脉压(24hAPP)、白昼脉压(dPP)、夜间脉压(nPP)水平显著增大,24h平均收缩压(24hASBP)、夜间平均收缩压(nSBP)水平显著升高,24h平均舒张压(24hADBP)、白昼平均舒张压(dDBP)、夜间平均舒张压(nDBP)水平显著下降,而2组间dSBP比较无统计学意义;(2)老年高血压患者IMT增厚组的24hAPP、dPP和nPP水平均显著高于IMT正常组;(3)与动态PP<60mmHg者比较,动态PP≥60mmHg的高血压患者冠心病发生率显著升高;(4)与动态PP<60mmHg者比较,动态PP≥60mmHg的单纯高血压患者的IMT显著增厚。结论动态PP增大是老年高血压患者颈动脉粥样硬化及未来发生冠心病的重要危险因素。     

颈动脉斑块及主动脉脉压对冠状动脉病变严重程度的相关性研究

1 资料与方法 回顾性分析2007年1～11月我院拟诊冠心病行冠状动脉造影术和颈动脉超声的276例患者,男206例,女70例,平均年龄(62.7±7.2)岁.根据有无颈动脉斑块(cAP)和主动脉脉压(PP)水平分为:A组142例(有CAP PP≥65mm Hg,1 mm Hg=0.133 kPa)、B组30例(无CAP PP≥65 mm Hg)、C组39例(有CAP PP<65 mm Hg)、D组65例(无CAP PP<65 mm Hg).排除继发性高血压、瓣膜病、先天性心脏病、主动脉夹层、7日内患急性心肌梗死者.     

老年高血压患者脉压与动脉硬化及动脉内皮功能关系的研究

目的研究脉压(PP)与颈动脉粥样硬化及肱动脉内皮功能的关系。方法对165例中老年患者行颈动脉及肱动脉超声检查,测得颈动脉内膜中层厚度(IMT)及肱动脉加压前后内径,并测压。以PP<60mmHg、60mmHg≤PP<80mmHg和PP≥80mmHg分为三个亚组进行分析。结果随着PP的增加,颈动脉IMT、血管僵硬度、斑块发生率升高,内皮依赖性血管舒张功能(FMD)、血管扩张性下降。直线相关性分析发现,PP与颈动脉IMT、FMD、血管僵硬度及扩张性相关性较强,以IMT及FMD为应变量,对各危险因素进行多元回归分析发现,进入回归方程的都有PP和年龄。结论PP与动脉粥样硬化和内皮功能相关,PP可能参与动脉粥样硬化的形成和发展。     

2型糖尿病患者脉压与血管病变的相关性研究

目的:研究2型糖尿病(DM)患者脉压(PP)大小与其血管病变的相关性.方法:以145例2型DM患者为研究对象,根据PP水平分为A组[PP<60 mmHg(1 mmHg=0.133 kPa)],B组(PP≥60 mmHg).比较2组患者冠状动脉病变积分、血β2-微球蛋白、尿β2-微球蛋白的差异.结果:2组患者相比:B组冠状动脉病变积分、血β2-微球蛋白、尿β2-微球蛋白显著高于A组(P<0.01).logistic逐步回归分析发现PP是冠状动脉病变积分、血β2-微球蛋白、尿β2-微球蛋白的独立危险因素.结论:PP是预测2型DM患者血管病变严重程度的参考指标.     

Research and Evaluation of the Influence of the Construction of the Gate and the Influence of the Piston Velocity on the Distribution of Gases into the Volume of the Casting

Distribution of gasses to the cast volume and volume of pores can be maintained within the acceptable limits by means of correct setting of technological parameters of casting and by selection of suitable structure and gating system arrangement. The main idea of this paper solves the issue of suitability of die casting adjustment—i.e., change of technological parameters or change of structural solution of the gating system—with regards to inner soundness of casts produced in die casting process. Parameters which were compared included height of a gate and velocity of a piston. The melt velocity in the gate was used as a correlating factor between the gate height and piston velocity. The evaluated parameter was gas entrapment in the cast at the end of the filling phase of die casting cycle and at the same time percentage of porosity in the samples taken from the main runner. On the basis of the performed experiments it was proved that the change of technological parameters, particularly of pressing velocity of the piston, directly influences distribution of gasses to the cast volume.     

Weighing the QT Intervals with the Slope or the Amplitude of the T Wave

Objective: The reproducibility of QT interval measurements is low, even for the mean QT interval based on the standard ECG. In this study we analyzed whether the reproducibility of the mean weighed QT interval was better than the simple mean QT interval. The weighing was based on the amplitude of the T wave or the slope of the steepest tangent on the terminal part of the T wave. Material and methods: 12‐lead ECGs of 130 postmyocardial infarction patients were obtained. The QT intervals were measured by the tangent‐method on two occasions by the same observer Mismatch QT intervals were defined as QT intervals that were measured at only one occasion. Sixteen ECGs were rejected. The data were split into 34 and 80 ECGs for optimization and validation of the weighing, respectively. The weighed QT dispersion was calculated as the weighed mean of the three longest minus the weighed mean of the three shortest QT intervals. Results: Weighing with the slope increased the reproducibility by 41% (P = 3 10^‐6), but weighing with the amplitude reduced it by 20% (P = 0.02). However, if measurements with errors above 75 ms were rejected, weighing with the slope or the amplitude increased the reproducibility with 26% and 20% (P = 0.02), respectively. Weighing did not change the reproducibility of the weighed QT dispersion. Conclusion: Weighing with the slope improved the reproducibility of the mean weighed QT interval. However, if measurements with errors above 75 ms were rejected, weighing with the amplitude also increased the reproducibility. Weighing did not change the reproducibility of the weighed QT dispersion. Weighing is particularly efficient at reducing the negative impact of mismatch QT intervals on the reproducibility. A.N.E. 2002;7(1):4–9     

县级以下综合医疗机构医务人员对现代结控知识的认识现状调查

目的本文旨在了解医务人员现代结控知识掌握的现状及培训效果?方法于培训前后进行问卷调查,内容包括:病例发现?结核病诊断及化疗?结果培训前疫情报告和转诊,回答正确者占75.2%?71.7%;对临床表现?查痰和诊断依据,回答正确者占83.5%?42.5%?40.8%;抗痨药物?用药方法?化疗原则?短化方案?短化疗程?治愈标准六项,回答正确者占58%?14.4%?20.8%?9.2%?17%?24.3%?培训后再次调查发现,90%以上医务人员对现代结控基本知识已掌握?结论各级医务人员现代结控知识是很贫乏的,因此,对其进行系统培训是极为必要的,此项工作省时?省力?投入少,可收到事半功倍的效果。     

大骨节病病区水,粮实验对动物的骨和软骨中化学元素组成的影响

用质子激发 X 线荧光分析方法(PIXE)测定了大骨节病病区和非病区的水、粮以及用该水粮喂养的大白鼠的肋软骨和硬骨中22种化学元素的含量。结果发现水粮中存在差异的元素反应在用该水粮喂养的大白鼠的骨、软骨中也存在差异,含量都低的元素有 P、Mn、Cu、As、Zn。都高的有铅。其中锌低在水、粮、硬骨和软骨中都完全一致呈非常显著性差异(p<0.01)。提示病区水、粮中化学元素对骨质的影响不是单一元素缺乏或过多所致,而是多种元素的复合因素。     

Assessment of the Soft-Tissue Seal at the Interface between the Base of the Fixed Denture Pontic and the Oral Mucosa

Fixed dentures (bridges) are often selected as a treatment option for a defective prosthesis. In this study, we assess the contact condition between the base of the pontic and oral mucosa, and examine the effect of prosthetic preparation and material biocompatibility. The molars were removed and replaced with experimental implants with a free-end type bridge superstructure after one week. In Experiment 1, we assessed different types of prosthetic pre-treatment: (1) the untreated control group (Con: mucosa recovering from the tooth extraction); (2) the laser irradiation group (Las: mucosa recovering after the damage caused by a CO₂ laser); and (3) the tooth extraction group (Ext: mucosa recovering immediately after the teeth extraction). In Experiment 2, five materials (titanium, zirconia, porcelain, gold-platinum alloy, and self-curing resin) were placed at the base of the bridge pontic. Four weeks after the placement of the bridge, the mucosa adjacent to the pontic base was histologically analyzed. In Experiment 1, the Con and Las groups exhibited no formation of an epithelial sealing structure on the pontic base. In the Ext group, adherent epithelium was observed. In Experiment 2, the sealing properties at the pontic interface were superior for titanium and the zirconia compared with those made of porcelain or gold-platinum alloy. In the resin group, a clear delay in epithelial healing was observed.     

高胆红素血症对肿瘤标志物测定的影响探讨

目的探讨高胆红素血症对Ca19-9、Ca24-2和CEA检测的影响.方法对320例胆管、胆囊良恶性疾病病人,15例胆囊炎病人的胆汁和血清以及10例肝硬化、10例黄疸肝炎病人进行Ca19-9、Ca24-2和CEA检测.结果在良性胆管、胆囊疾病中,Ca19-9的假阳性最高;在胆红素增高的良性疾病中,Ca19-9假阳性率达46.7%;15例胆汁和血清以及10例肝硬化和10例黄疸肝炎病人中,Ca19-9的假阳性率分别为93%、20%、80%和80%.结论高胆红素血症对Ca19-9检测影响最明显,胆囊、胆管良恶性疾病鉴别时,以Ca24-2和CEA检测为佳.     

Echocardiography in the Emergency Department: From the Perspective of the Emergency Physician and the Cardiologist

Echocardiography performed in the emergency department must adapt to this new setting for noninvasive diagnostic testing. Emergency physicians require echocardiography to provide rapid diagnosis in life-threatening emergencies. New initiatives are being proposed by emergency physicians in the delivery of this test. Cardiologists now use echocardiography in the emergency-department to make the diagnosis of heart disease earlier and with greater accuracy.