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《Clinical gastroenterology and hepatology》2023,21(2):370-379
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Mark Hensey Richard A. Brown Sudish Lal Janarthanan Sathananthan Jian Ye Anson Cheung Philipp Blanke Jonathon Leipsic Robert Moss Robert Boone John G. Webb 《JACC: Cardiovascular Interventions》2021,14(5):489-500
Growing clinical data support the use of transcatheter therapies for significant mitral valve disease. Currently, edge-to-edge repair is the transcatheter treatment of choice, but many anatomies are not suitable. Transcatheter mitral valve replacement offers several potential advantages over transcatheter repair, most notably a greater and more sustained reduction in mitral regurgitation post-implantation, but also potential disadvantages. To enable the successful treatment of mitral valve disease in a wide range of patients and anatomies, we require an armory of transcatheter devices, including transcatheter mitral valve replacement systems. 相似文献
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Karin Feldmann Carlo Maurer Katja Peschke Steffen Teller Kathleen Schuck Katja Steiger Thomas Engleitner Rupert Öllinger Alice Nomura Nils Wirges Aristeidis Papargyriou Rim Sabrina Jahan Sarker Raphela Aranie Ranjan Zahra Dantes Wilko Weichert Anil K. Rustgi Roland M. Schmid Roland Rad Maximilian Reichert 《Gastroenterology》2021,160(1):346-361.e24
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《Journal of the American College of Cardiology》2023,81(3):283-291
While in labor, a 37-year-old woman developed acute dyspnea, hypoxemia, and tachycardia. Transthoracic echocardiography demonstrated severe right ventricular dilation and dysfunction, raising the suspicion of acute pulmonary embolism. The patient indeed had bilateral pulmonary embolism, necessitating percutaneous thrombectomy. Her course was complicated by another saddle pulmonary embolus, heparin-induced thrombocytopenia, and COVID-19 infection. This clinical case illustrates the importance of prompt diagnosis of acute pulmonary embolism in a peripartum female patient, the multidisciplinary approach of management, and how to approach clinical complications such as heparin-induced thrombocytopenia. Furthermore, long-term management in acute pulmonary embolism is presented. 相似文献
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Rosanna Asselta Elvezia M. Paraboschi Alessio Gerussi Heather J. Cordell George F. Mells Richard N. Sandford David E. Jones Minoru Nakamura Kazuko Ueno Yuki Hitomi Minae Kawashima Nao Nishida Katsushi Tokunaga Masao Nagasaki Atsushi Tanaka Ruqi Tang Zhiqiang Li Yongyong Shi Pietro Invernizzi 《Gastroenterology》2021,160(7):2483-2495.e26
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《Clinical gastroenterology and hepatology》2023,21(2):456-466.e7
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《JACC: Cardiovascular Interventions》2020,13(20):2418-2426
ObjectivesThe aim of this study was to examine the initial experience with a novel transseptal transcatheter mitral valve replacement (TMVR) system.BackgroundTransseptal TMVR may offer a less invasive option than surgery for mitral regurgitation (MR) with greater efficacy and fewer anatomic limitations than transcatheter repair.MethodsPatients were treated with the EVOQUE TMVR system from September 2018 to October 2019. Key inclusion criteria were moderate or greater MR, New York Heart Association functional class ≥II, and high or prohibitive surgical risk. The primary outcome was technical success, defined by Mitral Valve Academic Research Consortium criteria.ResultsFourteen patients were treated, all with at least moderate to severe MR. The median age was 84 years, and the median Society of Thoracic Surgeons score was 4.6%. MR was degenerative in 4 (28.6%), functional in 3 (21.4%), and mixed in 7 (50%). Technical success was achieved in 13 patients (92.9%), and 1 patient was converted to surgery. At 30 days there was 1 noncardiovascular mortality (7.1%), 2 strokes (14.3%), no myocardial infarctions, and no rehospitalizations. Two patients (14.3%) underwent paravalvular leak closure. One patient (7.1%) underwent alcohol septal ablation for left ventricular outflow tract obstruction. Including the 2 patients with paravalvular leak closure, MR was mild or less in all implanted patients at 30 days, with no MR in 10 (83.3%). Mean mitral gradient was 5.8 mm Hg (median). New York Heart Association functional class improved to ≤II in 9 patients (81.8%).ConclusionsThis first-in-human experience has demonstrated the feasibility of the transseptal EVOQUE TMVR system. Further clinical studies are required to establish safety and clinical outcomes. 相似文献
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《Clinical gastroenterology and hepatology》2023,21(2):264-279
Recurrent abdominal pain is a common reason for repeated visits to outpatient clinics and emergency departments, reflecting a substantial unmet need for timely and accurate diagnosis. A lack of awareness of some of the rarer causes of recurrent abdominal pain may impede diagnosis and delay effective management. This article identifies some of the key rare but diagnosable causes that are frequently missed by gastroenterologists and provides expert recommendations to support recognition, diagnosis, and management with the ultimate aim of improving patient outcomes. 相似文献
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Bashar J. Qumseya Yazan Qumsiyeh Sandeep A. Ponniah David Estores Dennis Yang Crystal N. Johnson-Mann Jeffrey Friedman Alexander Ayzengart Peter V. Draganov 《Gastrointestinal endoscopy》2021,93(2):343-352.e2
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