首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到18条相似文献,搜索用时 78 毫秒
1.
目的 通过多元统计和社会网络分析法中主题词共现的方式,研究儿童心血管学科知识发展、分布,研究学科知识聚类,并预测未来发展趋势。方法 于2012年12月以PubMed数据库心血管疾病Mesh主题树下全部主要主题词/副主题词,选取全部心血管专科杂志,影响因子>1的内科综合杂志和儿科学杂志检索文献,同时将研究分为1966至1980年、1981至1990年、1991至2000年和2001至2010年4个时间段,在每个时间段中分别使用书目共现分析系统及Endnote X6提取主要主题词/副主题词,建立共词矩阵。之后使用SPSS 22.0软件对共现矩阵进行转换、降维和聚类分析,并根据聚类分析结果绘制战略坐标图。最后使用Ucinet 6.0软件绘制可视化网络。结果 共提取文献50 200篇。成功建立儿童心血管学科知识发展可视化图谱,直观展示全球范围内儿童心血管学科知识发展。1966至1980年儿童心血管学科以心血管疾病的病理生理学及病因学研究为主,发展方向相对局限,所关注疾病种类较少。1981至1990年先天性心脏病逐步成为研究核心,聚类归纳较好,新兴研究领域发展稍显不足;同时通过超声心动图的广泛应用,在一定程度上推动整个学科发展。1991至2010年先天性心脏病整体治疗及保护性策略研究成为核心,并伴随多种治疗手段如导管治疗、心脏移植等的逐步应用,各个聚类间发展更为平衡,知识更新快速,学科研究所关注疾病种类进一步增多。结论 目前儿童心血管学科发展良好,研究热点与时代发展相联系。新型诊断技术及治疗手段对于学科发展推动力显著,儿童心血管学科知识网络逐渐完善,先天性心脏病已成为儿童心血管学科的核心问题。  相似文献   

2.
目的 通过多元统计和社会网络分析法中关键词共现的方式,研究中国先天性心脏病(CHD)介入诊断治疗的学科知识分布,研究学科知识聚类,并预测未来发展趋势。 方法 2011年3月以主题词“心脏缺损,先天性”和“心脏导管插入术”在中国生物医学文献数据库(CBM)检索文献;使用Endnote X4软件提取关键词,建立共词矩阵;使用SPSS 17.0软件对共现矩阵进行转换、降维和聚类分析,并根据聚类分析结果绘制战略坐标图;使用Ucinet 6.0软件绘制可视化网络。 结果 共命中文献1 015篇。成功建立中国CHD介入诊断治疗学科知识可视化图谱,直观展示了中国CHD介入诊断治疗学科的知识分布,并形成重点研究聚类,提示治疗,方法和设备,超声心动图等学科知识发展较好。 结论 中国CHD学科知识以治疗聚类为中心,且多学科知识聚类共同发展;同时材料和设备的相关研究在CHD学科发展中具有显著推动作用,超声心动图及肺动脉高压在CHD学科知识中地位重要。  相似文献   

3.
儿童保健研究内容与发展方向   总被引:2,自引:0,他引:2  
进入21世纪后,随着我国经济发展而出现的现代化、工业化、城市化和全球化,儿童保健正处于一个新的历史发展阶段——研究儿童新的疾病及宏观、微观环境对儿童健康的影响。一、生长发育我国儿童体格生长长期呈增长趋势。李辉等[1]研究绘制了我国7岁以下儿童的年龄别体质量、年龄别身高、身高别体质量及3岁以下儿童的年龄别头围的百分位曲线图,用生长监测指标评价儿童体格生长状况。由于近年来儿童肥胖发生率呈上升趋势,儿童体型、匀称度在发生改变,对此现象的一个评价指标——体质量指数(BMI),我国已有了7岁以下儿童的参照值[2]。用这些指标…  相似文献   

4.
《中国儿童保健杂志》属教育部主管、西安交通大学与中华预防医学会联合主办的技术性杂志,是我国唯一一部儿童保健领域的专业性国家级刊物。杂志以反映中外儿童保健学的学术动态和科研成果,交流优生、优育、优教知识及儿童管理经验,介绍新的适宜技术,提高儿保工作者素质,促进儿童正常发展为宗旨。几年来,我刊深受国内外儿保界专家、教授及广大基层儿保工作者的喜爱。属中国高校优秀期刊、中华预防医学会系列优秀期刊,被《美国化学文摘》录入源期刊、俄罗斯《文摘杂志》录入源期刊、中国科技论文统计源期刊、中国生物医学文献数据库源期刊等国内外十几家大型知名数据库收录。本刊为月刊,大16开本,96页,每期定价10.00元,全年120.00元。栏目设置:科研论著、专家笔谈、应用论著、综述、基础研究论著、经验交流、基层儿保园地等栏目。服务对象:全国各地图书馆、资料库、儿科医  相似文献   

5.
目的 分析代谢异常型肥胖(metabolically unhealthy obesity,MUO)和代谢正常型肥胖(metabolically healthy obesity,MHO)儿童的全血转录组特征,探讨MUO的生物标志物。方法 采用Gene Expression Omnibus(GEO)数据库的GSE146869数据集,包括27例肥胖儿童的全血转录组测序数据,其中13例MHO儿童,14例MUO儿童。利用R软件的“Limma”包,分析全血细胞中的差异表达基因。使用基因本体论(gene ontology,GO)富集分析、京都基因与基因组百科全书(Kyoto encyclopedia of genes and genomes,KEGG)富集分析、蛋白互作(protein-protein interaction,PPI)网络分析等生物信息学方法,探索差异表达基因的生物学功能。使用加权基因共表达网络分析(weighted gene co-expression network analysis,WGCNA),将差异表达基因聚类为模块,探索MUO的生物标志物或潜在治疗靶点。使用R软件进行生物...  相似文献   

6.
目的探讨家庭养育环境对发育性语言障碍(DLD)儿童语言发育和社会情绪的影响。方法采用1~3岁儿童家庭养育环境量表、Gesell发育诊断量表和1~3岁幼儿情绪及社会性发展量表对125例DLD儿童进行测评。130例年龄、性别匹配的语言发育正常的儿童作为对照组。结果 DLD组儿童的家庭养育环境中不良环境所占比例显著高于对照组,家庭养育环境中的各领域得分均显著低于对照组(P0.05)。DLD儿童的家庭养育环境得分与儿童的语言发育水平(r=0.536,P0.01)、社会情绪中的能力域得分(r=0.397,P0.01)呈正相关,与社会情绪中的外显行为域、内隐行为域、失调域得分呈负相关(r分别为-0.455、-0.438、-0.390,P0.01)。DLD儿童的家庭养育环境对儿童的语言发育水平有直接的影响,也通过社会情绪的中介效应影响儿童的语言发育水平。结论家庭养育环境影响DLD儿童的语言发育和社会情绪;社会情绪在儿童家庭养育环境和语言发育中起部分中介效用。  相似文献   

7.
目的探索儿童神经心理行为检查量表2016版(以下简称“儿心量表”)鉴别孤独症谱系障碍(autism spectrum disorder,ASD)和全面发育迟缓(global developmental delay,GDD)的效能及其所需指标。方法回顾性选取18~48月龄的ASD(n=277)和GDD(n=415)患儿为研究对象,采用儿心量表评估两组儿童在大运动、精细运动、适应能力、语言、社会行为、警示行为6大能区的发育水平,并将获得的智龄和发育商(developmental quotient,DQ)共13个指标的数据作为特征,应用5种机器学习(machine learning,ML)分类器进行模型训练,计算各分类器对两组被试的分类准确度、灵敏度和特异度。结果警示行为DQ同时在5个分类器中作为第一个特征被选中,且在使用警示行为DQ单个特征时,分类准确度达到78.90%;当警示行为DQ与警示行为智龄、大运动智龄和语言能力智龄协同作用时,最高分类准确度为86.71%。结论ML结合儿心量表能有效区分ASD和GDD儿童;警示行为DQ在ML中起重要作用,而与其他特征联合能提高分类的准确度,对临床高效、准确鉴别ASD和GDD儿童有一定的提示意义和参考价值。  相似文献   

8.
目的 探求早期反应性依恋障碍对早产儿婴幼儿期社会生活能力和行为的影响.方法 选取307例早产儿,将其中确诊为反应性依恋障碍的66例作为研究对象进行随访;选择无依恋障碍且无其他各类疾病的早产儿66例作为对照组.2组儿童均追踪随访至2岁.采用问卷调查收集研究对象人口统计学特征及家庭环境状况.儿童的社会能力评定采用婴儿-初中生社会生活能力量表,并选用2~3岁儿童行为量表(CBCL)评定其情绪及行为问题.结果 在行为方面,除了攻击行为因子,其他各因子分在2组间差异均有统计学意义(Pa<0.01,0.05),行为问题的检出率早产伴反应性依恋障碍组明显高于对照组(P<0.01).早产伴反应性依恋障碍组儿童的社会生活能力得分低于对照组,差异有统计学意义(P<0.05).结论 早产伴反应性依恋障碍儿童较无依恋障碍早产儿童有更多的行为和心理问题,提示建立和谐的亲子关系和良好的家庭养育环境,对更好地促进早产儿全面、健康的发展有重要意义.  相似文献   

9.
目的辨证论治是中医防治疾病最主要的方法和手段,完善现有优势病种的诊疗规范,使证候的诊断客观化、标准化和规范化,有利于中医学的推广与发展。本研究提出一种基于数据挖掘技术生成中医辨证动态量表的方法,将其应用于儿童肺炎的中医辨证规范。方法选择6家中医和1家西医院作为儿童肺炎中医辨证规范研究的参研单位,将同时符合中医儿童肺炎喘嗽常证、西医儿童肺炎轻症诊断标准的患儿纳入研究组;辽宁中医药大学附属医院诊断的儿童非肺炎病例作为验证组。对所采集的儿童肺炎临床证候信息进行聚类挖掘和关联分析,生成儿童肺炎所属各证的基本构成和构成比、儿童肺炎各证所属症状的构成比,在证中证候组成模型和证间证候贡献模型的基础上构造儿童肺炎辨证量表。对量表的信度和效度进行评价。结果研究组纳入1063例,验证组纳入2000例。通过对既往儿童肺炎中医研究文献的复习,汇总216项对儿童肺炎病证诊断有临床意义的证候变量,覆盖与儿童肺炎有关的30个方面。经过聚类处理后,有临床意义与统计学意义的指标有109项。痰热闭肺、风热闭肺、气阴两虚、阴虚肺热、痰浊未尽、痰热未清、风寒闭肺和毒热闭肺证量表的信度分别为0.742、0.583、0.666、0.258、0.370、0.559、0.797和0.861。内容效度系数较高的症状为:痰热闭肺证为小便(0.611)、咽喉症状(0.585)、口渴(0.575)、脉象/数(0.548)、厚苔(0.442)、痰/性质(0.42)、发热/性质(0.418)和咳嗽/程度(0.412);风热闭肺证为咽部症状(0.658)、咳嗽/程度(0.572)、汗/程度(0.535)和脉象/数(0.52);气阴两虚证为脉象/无力(0.876)、脉象/细(0.847)、咳嗽/声音(0.742)、腻苔(0.695)和痰/性质(0.551);阴虚肺热证为脉象/数(0.551)、痰-性质(0.535)、脉象/细(0.488)、剥脱苔(0.409);痰浊未尽证为脉象/数(0.534)、脉象/滑(0.533)、痰/量(0.41)和厚苔(0.407);痰热未清证为脉象/滑(0.611)、咳嗽/程度(0.598)、痰/性质(0.548)、痰/量(0.428)、痰/颜色(0.427)、脉象/数(0.425)和厚苔(0.406);风寒闭肺证为小便(0.927)、咽部症状(0.9)、精神神志/程度(0.879)、痰/性质(0.732)、腻苔(0.63)、哮鸣音(0.55)和脉象/紧(0.409);毒热闭肺证为咳嗽/程度(0.891)、口渴(0.824)、大便(0.813)、指纹性质(0.8)、发热/性质(0.771)、指纹程度(0.748)、腻苔(0.642)、咳嗽/声音(0.58)和发热/温度(0.481)。结论数据挖掘技术支持儿童肺炎的病证结合辨证规范和辨证标准的建立,是可行的技术方法。研究所形成的儿童肺炎辨证量表是有效的辨证标准化的评估方法。  相似文献   

10.
目的 探讨HACE1和LIN28B基因多态与中国汉族儿童神经母细胞瘤的相关性。方法 采用病例对照研究,收集246例中国汉族神经母细胞瘤患儿和328例中国汉族健康儿重标本,提取外周血DNA,通过PCR扩增目的基因片段,随后应用Sequenommassarray对目的片段进行测序分型。并采用卡方检验、校验后Logistic回归分析等统计学方法,比较各SNP位点与NB肿瘤发生发展相关性。结果 HACE1基因rs45521835位点携带AA基因型的患儿以及rs6927608位点携带CC基因型的患儿其NB肿瘤始发于肾上腺较多,OR值分别为5.20(95%CI:1.06~25.56,P:0.047)和5.00(95%CI:1.02~24.55,P=0.052)。LIN28B基因SNP位点rs7759938(CC基因型)、rs314280(TTT基因型)、rs314276(AA基因型)和rs314263(CC基因型)主要与GNB密切相关,OR值分别2.94(95%CI:1.06~8.20,P=0.047)、2.94(95%CI:1.06~8.20,P=0.047)、2.95(95%CI:1.06~8.24,P=0.047)和3.02(95%CI:1.08~8.41,P=0.042)。结论 在中国汉族儿童中,HACE1基因(rs45521835,rs6927608)和LIN28B基因(rs7759938,rs314280,rs314276,rs314263)SNPs与原发于肾上腺的神经母细胞瘤或者节细胞性神经母细胞瘤(GNB)密切相关。  相似文献   

11.
12.
13.
Aim: To study uptake of care at the antenatal and child health clinic (CHC), and maternal and child health up to 5 years after the birth, as reported by mothers with a non‐Swedish speaking background (NSB). Methods: A sample of 300 women with a NSB, 175 originated from a poor country and 125 originated from a rich country, were compared with a reference group of 2761 women with a Swedish speaking background. Four postal questionnaires were completed: during pregnancy, and 2 months, 1 year and 5 years after the birth. Results: Mothers with a NSB from a poor country of origin did not differ from the reference group of mothers with a Swedish speaking background regarding number of clinic visits, but they had a lower attendance rate at antenatal and postnatal education classes. Depressive symptoms, parental stress and poor self‐rated health were more common in these women, and they reported more psychological and behavioral problems in their 5‐year olds. Women with a rich country origin did not differ from the reference group regarding maternal and child health, but had a lower uptake of all out‐patient care, except parental classes after the birth. Conclusion: Women originating from a poor country seem to be under great stress during pregnancy and the child's first years.  相似文献   

14.
Abstract The aim of the present study was to evaluate the rationality of health check-ups by a physician of 18-month-old children. The study population consisted of all 4075 children in Uppsala county who were 18 months old in 1994 and should have had a routine health examination at that point. Information about the 18-month health examination came from primary data in a longitudinal child health register regarding all children of preschool age. The children in the study population were classified into two main categories, namely children with no newly detected health problem (92.6%) and children in whom a new health problem was detected (3.3%). Data from the register and other sources were analysed to categorize the health problems by severity and type and to determine who (parents, nurse or physician) had identified each. Among the 4075 children in the study population, 135 children were identified as having a newly detected health problem. One-third of them were actually healthy (false positive). Among the 92 verified new health problems (2.3%), 48 were minor, 42 were moderate and 2 were severe. More than half of the moderate health problems were transient infections. The main conclusion of the study is that, undercurrent conditions in Sweden, it would be reasonable to replace the 18-month examination by a physician with an examination by a nurse, this examination being particularly orientated towards developmental and psychosocial problems.  相似文献   

15.
Aim: To investigate how nurses in Swedish child health care perceived working with fathers, and to what extent they offered support to, and included fathers in clinical encounters. Methods: A random sample of all nurses in Swedish child health care, 499 nurses, were asked to complete a postal questionnaire. The response rate was 70%. Data were analysed with content analysis, the chi‐square test and logistic regression models. Results: Almost all of the nurses found working with fathers positive. Fathers’ participation in child health care was much lower than that of mothers’. Almost 90% of the nurses estimated that it rarely came to their attention that a father was distressed, and less than one of five nurses had offered supportive counselling to any distressed father in the previous year. Nurses with regular supervision on mental health issues and nurses with a paediatric specialization were more likely to offer supportive counselling to fathers. Approximately 50% of the nurses had an ambivalent attitude towards fathers’ caring capacity when compared to that of mothers. Conclusions: Fathers received less support from child health nurses, and many nurses were ambivalent about fathers’ caring abilities. Methods need to be developed to involve both parents in child health care.  相似文献   

16.
OBJECTIVES: To report baseline mental health measures from the Children in Care study, a prospective epidemiological study of children in court-ordered foster and kinship care in New South Wales, Australia. METHODS: Mental health, socialization and self-esteem were assessed in 347 children in a statewide mail survey, using two carer-report checklists, the Child Behavior Checklist (CBCL) and the Assessment Checklist for Children (ACC). RESULTS: Children in the study had exceptionally poor mental health and socialization, both in absolute terms, and relative to normative and in-care samples. Levels and rates of disturbance for children in foster care exceeded all prior estimates. Rates of disturbance for children in kinship care were high, but within the range of prior estimates. Boys presented with higher scope and severity of mental health problems than girls on the CBCL, while gender-specific patterns of disturbance were shown on the ACC. A moderate age effect was accounted for by children's age at entry into care. CONCLUSIONS: Children in care are at high risk of mental health problems. Psychological support for the children and their carers is an essential secondary prevention strategy. Implications for service delivery are discussed.  相似文献   

17.
18.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号