云南省伤寒副伤寒空间分布特征及其气候影响因素研究

Objective To characterize the spatial distribution of typhoid and paratyphoid fever(TPF)in Yunnan province, China and to determine the effectiveness of meteorological factors on the epidemics of TPE Methods Data of reported TPF cases in Yunnan province(2001 -2007)from the China Information System for Diseases Control and Prevention was applied to GIS-based spatial analyses to detect their spatial distribution and clustering of TPF incidence at the county level.Panel data analysis was used to identify the relationships between the TPF incidence and meteorological factors including monthly average temperature, monthly cumulative precipitation and monthly average relative humidity. Results During the study period, the average incidence of TPF in Yunnan province was 23.11/100 000, with majority of the TPF cases emerged in summer and autumn. Although widely distributed, two TPF clusters were detected in Yunnan province based on the spatial analysis:one area around Yuxi city with the average annual incidence as 207.45/100 000 and another at the junctions of Yunnan province with Burma and Laos. Based on results from panel data analysis, the incidence of TFP was shown to be associated with meteorological factors such as temperature,precipitation, relative humidity and one month lag of temperature increase [10 ℃ increase in the monthly average temperature:IRR=1.30(95%CI: 1.24-1.36);10% increase in monthly average relative humidity:IRR= 1.07(95%CI: 1.05-1.09); 100 mm rise in monthly cumulative precipitation:IRR=1.02(95%CI: 1.00-1.03); and 10 ℃ average temperature increase, the last month: IRR=1.73(95%CI: 1.64-1.82)]. Conclusion Areas with high TPF incidence were detected in this study,which indicated the key areas for TPF control in Yunnan province. Meteorological factors such as temperature, precipitation and humidity played a role in the incidence of TPF.     

云南省伤寒副伤寒空间分布特征及其气候影响因素研究

Objective To characterize the spatial distribution of typhoid and paratyphoid fever(TPF)in Yunnan province, China and to determine the effectiveness of meteorological factors on the epidemics of TPE Methods Data of reported TPF cases in Yunnan province(2001 -2007)from the China Information System for Diseases Control and Prevention was applied to GIS-based spatial analyses to detect their spatial distribution and clustering of TPF incidence at the county level.Panel data analysis was used to identify the relationships between the TPF incidence and meteorological factors including monthly average temperature, monthly cumulative precipitation and monthly average relative humidity. Results During the study period, the average incidence of TPF in Yunnan province was 23.11/100 000, with majority of the TPF cases emerged in summer and autumn. Although widely distributed, two TPF clusters were detected in Yunnan province based on the spatial analysis:one area around Yuxi city with the average annual incidence as 207.45/100 000 and another at the junctions of Yunnan province with Burma and Laos. Based on results from panel data analysis, the incidence of TFP was shown to be associated with meteorological factors such as temperature,precipitation, relative humidity and one month lag of temperature increase [10 ℃ increase in the monthly average temperature:IRR=1.30(95%CI: 1.24-1.36);10% increase in monthly average relative humidity:IRR= 1.07(95%CI: 1.05-1.09); 100 mm rise in monthly cumulative precipitation:IRR=1.02(95%CI: 1.00-1.03); and 10 ℃ average temperature increase, the last month: IRR=1.73(95%CI: 1.64-1.82)]. Conclusion Areas with high TPF incidence were detected in this study,which indicated the key areas for TPF control in Yunnan province. Meteorological factors such as temperature, precipitation and humidity played a role in the incidence of TPF.     

判定传染病发病时间聚集性五种方法的比较与探讨

探讨并比较判定传染病发病时间聚集性的五种方法.以郑州市金水区2008-2010年细菌性痢疾发病时间聚集性的判定为例,比较可用于传染病发病时间聚集性分析和判定的聚类分析、游程检验、负二项分布、圆分布、集中度五种方法.聚类分析得出5-9月是发病流行期,8月是发病高峰期;游程检验得出2008和2009年月发病具有聚集性(P＜0.05),2010年发病月分布具有随机性;集中度法得出2008-2010年每年月发病分布均有一定的聚集性,从M值看聚集程度逐年减弱;圆分布法得出2008-2010年每年均具有发病聚集倾向时间(P＜0.01),3年依次为7月11、29日和8月24日;负二项分布拟合得出在年度日发病层面2008和2010年具有聚集性(P＞0.05),2009年不具有聚集性(P＜0.05).五种方法均可用于传染病发病时间聚集性的分析和判定,可根据不同情况选择.[Introduction] To demonstrate and evaluate five different methods in the determination of temporal clustering on infectious diseases.The incidence rates of bacillary dysentery in Jinshui district,Zhengzhou city,Henan province from 2008 to 2010 were analyzed by 5 different methodsCluster Analysis,Runs Test,Negative Binomial Distribution,Circular Distribution and Concentration Ratio.Through Cluster Analysis,data showed that the epidemic period was from May to Sept.with August as the peak.Runs Test confirmed a cluster of month-incidence in 2008 and 2009 (P＜0.05)and a random distribution in 2010.The Concentration Ratio showed a weakened seasonal incidence cluster to a certain extent by M from 2008 to 2010.The Circular Distribution demonstrated an inclining cluster of time (P＜0.01) and it was on July 11th and 29th,as well on August 24th in 2008,2009 and 2010.In terms of day-incidence,the Negative Binomial Distribution presented a cluster in 2008 and 2010,but with no significant difference in 2009.The five above said methods could flexibly be used in determining the temporal clustering of infectious disease at different occasions.     

Poisson分布和负二项分布对肾综合征出血热病例空间聚集性的拟合

目的 通过对肾综合征出血热病例县区层面空间聚集性的拟合,展示Poisson分布与负二项分布的详细计算过程.方法 对河南省2010年肾综合征出血热病例县区层面分布数据按发病数进行归类整理,利用Poisson分布与负二项分布原理对其进行拟合与检验.其中负二项分布聚集性参数k采用最大似然法估算.结果 Poisson分布x2=67.1213,P＜0.05;负二项分布聚集性参数k=0.8455,x2 =7.2543,P＞0.05.结论 河南省2010年肾综合征出血热病例在县区层面服从负二项分布,具有空间聚集性.     

拉米夫定联合阿德福韦酯与恩替卡韦治疗慢性乙型肝炎疗效比较

Objective To analyze the effect of lamivudine combined with adefovir and entecavir in treatment of chronic hepatitis B patients, to provide the basis for felicitous treatment. Methods 120 cases of chronic hepatitis B patients were divided into two groups(lamivudine combined with adefovir group and entecavir group) according to the method of treatment. The clinical data of two groups were recorded, including the cases of ALT normalization, HBeAg negative conversion and HBV DNA below to the detection level in different treatment time. Results After 3, 6, 12 months of treatment, there was no statistical difference between the two groups in ALT normalization ( x2 = 2.194,2.353,3.339, P＞ 0.05); and there was no statistical difference in the incidence of HBeAg negative after 3,6,12.18 months of treatment too(x2 = 0.054,0.139,0.326,0.152, P ＞ 0.05). There was no statistical difference in the incidence of HBV DNA returned to nagative after 6,12, 18,24 months trentment ( x2 = 0.348,0.348,2.236,0.776, P ＞ 0.05). Conclusions There was no difference in the ALT normalization, the incidence of HBeAg negative conversion and the incidence of HBV DNA retumed to nagative in lamivudine combined with adefovir and entecavir for chronic hepatitis B.     

浙江省狂犬病免疫效果病例-对照研究

目的 评价狂犬病疫苗免疫预防措施效果,并分析免疫失败的原因. 方法 对2005-2006年浙江省132例狂犬病病例和与其有同源暴露的狂犬病暴露者73名采用统一调查表进行入户个案面对面调查,采用病例-对照研究方法和非条件logistic回归分析研究探讨免疫预防措施效果和造成免疫预防失败的因素. 结果 14.4%(19/132)的病例和93.2%(68/73)的对照在狂犬病暴露后去医疗机构注射过狂犬病疫苗,对应的OR值(95%CI)为0.012(0.004～0.035);72.2%(13/18)的病例和7.7%(5/65)的对照末完成狂犬病疫苗注射,相对规范且完成全程注射者的OR值(95% CI)为15.60(3.85～63.26).暴露前免疫史与暴露后疫苗免疫对狂犬病暴露者均有一定的保护作用,以暴露后疫苗免疫保护作用为佳,两者的OR值(95%CI)分别为0.065(0.032～0.132)和0.012(0.004～0.035).分层分析表明暴露后疫苗免疫对狂犬病暴露者有保护作用,校正后的OR值(95% CI)为0.010(0.002～0.047).经济条件差、不知道狂犬病的危害等是未接种狂犬病疫苗的原因. 结论 狂犬病暴露后的疫苗免疫对狂犬病暴露者有很好的保护作用,未完成狂犬病疫苗注射是导致免疫失败的主要原因.

Abstract：

Objective This research was to evaluate the effect of pre-and post-exposure prophylaxis for rabies and to analyze the reasons of invalidation. Methods A case-control study was conducted in 132rabies patients and 73 subjects exposed to homologous rabies in Zhejiang province.All the subjects were investigated face to face by using the same questionnaires at home.Non-conditional logistic regression was used to analyze the effect of measures and the reasons of invalidation. Results 14.4%(19/132) of cases and 93.2%(68/73) of controls had post-exposure,which resulted in an OR (95% CI) of 0.012 (0.004-0.035).However,72.2%(13/18) of cases and 7.7%(5/65)of controls had not finished their postexposure,and thus had an OR (95% CI) of 15.60 (3.85-63.26).Stratified analysis stated that postexposure prophylaxis was a protective factor,with an OR(95% CI) of 0.01 (0.002-0.047).Poor financial condition and poor knowledge of rabies were the causes of nonvaccination. Conclusion Post-exposure prophylaxis could protect the people exposed to rabies well and unfinished post-exposure prophylaxis was the main reason for its invalidation.     

新兵人群A群流行性脑脊髓膜炎抗体的血清流行病学调查

Objective To investigate the distribution of serogroup A epidemic cerebrospinal meningitis antibody IgG in recruits, provide scientific evidence for further prevention and control of the disease. Methods By using ELISA, serogroup A epidemic cerebrospinal meningitis antibody IgG serum samples of 360 recruits, who came from 7 provinces during the past four years, were detected, and the positive rate was analysed. Results There was no statistical difference in serum serogroup A epidemic cerebrospinal meningitis antibody IgG levels in each years, which ranged from 66.67% to 96.67% with a average rate of 83.33%, content of antibody ranged from 6.23 μg/mL to 26.47 μg/mL with an average content of 12.42 μg/mL, regional difference existed. The higher level found in recruits from Hubei (96.67%) 、Shandong (91.43%)and Beijing (88.00%), and lower level from Henan (66.67%) and Shaanxi(72.50%). There was no significant correlation between the antibody IgG positive rate and education or occupation background of the recruits before their recruitment (χ2 = 0.12, P > 0.05). Conclusions The positive rate of serogroup A epidemic cerebrospinal meningitis antibody IgG in recruits range from 66.67% to 96.67%, antibody level range from 6.23 μg/mL to 26.47 μg/mL, with a average content of 12.42 (μg/mL. The positive rate for antibody IgG varies in different provinces. It is necessary to give vaccination and education for the recruits to prevent serogroup A epidemic cerebrospinal meningitis spreading.     

新兵人群A群流行性脑脊髓膜炎抗体的血清流行病学调查

Objective To investigate the distribution of serogroup A epidemic cerebrospinal meningitis antibody IgG in recruits, provide scientific evidence for further prevention and control of the disease. Methods By using ELISA, serogroup A epidemic cerebrospinal meningitis antibody IgG serum samples of 360 recruits, who came from 7 provinces during the past four years, were detected, and the positive rate was analysed. Results There was no statistical difference in serum serogroup A epidemic cerebrospinal meningitis antibody IgG levels in each years, which ranged from 66.67% to 96.67% with a average rate of 83.33%, content of antibody ranged from 6.23 μg/mL to 26.47 μg/mL with an average content of 12.42 μg/mL, regional difference existed. The higher level found in recruits from Hubei (96.67%) 、Shandong (91.43%)and Beijing (88.00%), and lower level from Henan (66.67%) and Shaanxi(72.50%). There was no significant correlation between the antibody IgG positive rate and education or occupation background of the recruits before their recruitment (χ2 = 0.12, P > 0.05). Conclusions The positive rate of serogroup A epidemic cerebrospinal meningitis antibody IgG in recruits range from 66.67% to 96.67%, antibody level range from 6.23 μg/mL to 26.47 μg/mL, with a average content of 12.42 (μg/mL. The positive rate for antibody IgG varies in different provinces. It is necessary to give vaccination and education for the recruits to prevent serogroup A epidemic cerebrospinal meningitis spreading.     

胰岛素抵抗及血清瘦素异常与糖尿病合并脂肪肝的关系研究

Objective To study the relations among insulin resistance,abnormality of serum leptin level soluble leptin receptor(sLR) and the development of fatty liver in type 2 diabetes mellitue (DFL), so as to detect the partial pathogenesis. Methods 196 patients with type 2 diabetes mellitus were selected to retrospective study. The DFL group consisted of 96 patients who had already developed to fatty liver, while the NDFL group included 100 patients with no fatty liver. Biochemical test and insulin resistance were analysisd, and the level of serum leptin and sLR were also examined. Results The level of blood triglyceride(TG), high density lipoprotein(HDL), very low density lipoprotein( VLDL) between two groups were all statistical differences (t = - 8.124, 4.882, - 3.576, P < 0.01). The TG, HDL and VLDL level in DFL group were (3.25 ± 1.92), (1.11 ±0.28), (1.53 ± 0.60) mmol/L respectively. There was also a statistical difference in HOMA-IR level between the two groups (t = - 4.748, P < 0.01). HOMA-IR in DFL group was (4.82± 2.94), but no statistical difference in secretive function of beta cells (t = 0.123, P > 0.05). There was statistical difference in level of serum leptin and sLR between the two groups (t = - 7.435,13.332, P < 0.01); the leptin and sLR in DFL group were (4.34± 2.05) and (1.71 ± 0.53) fig/L respectively. Meanwhile, Pearson analysis showed that the blood TG level of the DFL group was positively correlated with HOMA-IR and leptin ( r = 0.845, P< 0.01; r = 0.742, P< 0.01); serum leptin level was positively correlated with HOMA-IR level (r = 0.852, P<0.01). However, serum sLR level showed negative correlation ( r = - 0.587, P < 0.01). Conclusions Insulin resistance and abnormality serum level of leptin and sLR might be one of the important causes for DFL, while abnormal lipid metabolism might be the secondary cause for this biochemical change.     

恩替卡韦治疗慢性乙型肝炎患者免疫功能变化的研究

Objective To investigate the feature of immune function in chronic hepatitis B(CHB) patients with enticarvir (ETV) therapy. Methods The venous blood samples in health controls and CHB patients at different time points after ETV therapy were collected. Serum and PBMCs were isolated, HBV markers, HBV DNA, ALT, serum cytokines and the cytokines were stimulated by CD3/CD28 cells and HBcAg, the frequency of immune cells were detected and compared with pretreatment. Results ALT and HBV DNA levels in patients at the 4th week decreased significantly, which were (73.78 ±93.34) U/L and (3.98 ±0.75)IU/mL respectively (t =3.816,2.795, P< 0.05), and the both returned to normal after 48-week therapy of ETV. IFN γ in serum and two stimulation supernatant decreased significantly compared to baseline after 4-week therapy (t - 2.386,2.358,2.448, P < 0.05). IL-10 level in serum decreased to (78.12 ± 24.01) pg/mL and was still higher than that in the health controls at the 48th week( t = 2.823, P < 0.05). IL-17 in serum and two stimulation supernatant increased significantly compared to baseline at the 4th week (t = 3.580, 2.448,2.464, P<0.05). IL-22 in serum increased to (85.22± 38.37) pg/mL and was still lower than that in health controls at the 4th week 0 = 2.272, p<0.05).The frequency of Th1 and Th17 cells increased significantly at the 4th week (t = 2.386, 2.998, P < 0.05); and then decreased gradually but still higher than that in health controls at the 48th week. The frequency of Th2 cells increased obviously at the 4th week (t = 3.062,P<0.05), and was the highest at the 12th week, then was lower than that in health controls at the 48th week( t = 2.690, P < 0.05) .The frequency of Treg cells decreased to normal after the treatment. Conclusions ETV suppresses HBV replication efficiently, which may attenuate hepatic inflammation but impair the ability of HBV clearing in the disease.     

山东省平阴县农村地区出生缺陷聚集性分析

目的 分析山东省平阴县农村地区出生缺陷聚集性分布特征,为进一步病因学研究和防治提供线索和依据。方法 收集平阴县2004-2016年出生缺陷登记资料,描述出生缺陷地理分布,计算每个村庄的出生缺陷发病例数,对出生缺陷数据资料进行Poisson分布和负二项分布拟合优度检验。结果 出生缺陷发病数据不符合Poisson分布(χ²=30.33,P<0.001),但符合负二项分布(χ²=4.56,P=0.336)。结论 平阴县农村地区出生缺陷在村级层面上具有空间聚集性。     

2011年安徽省某县出生缺陷空间分布规律探讨

目的 探讨2011年安徽省某县出生缺陷的发生情况和出生缺陷病例村层面的聚集性.方法 对2011年1月1日～12月31日全县出生缺陷儿344例及围生儿数16 104例的村层面分布数据进行归类整理,利用Poisson分布和负二项分布原理对其进行拟合.结果 2011年该县出生缺陷率为2.1%;男性为2.3%,女性1.8%;早产儿或过期产儿出生缺陷率较高;出生缺陷病例在村层面不服从Poisson分布,而服从负二项分布.结论 2011年安徽省某县出生缺陷病例的发生具有村庄聚集性.     

2005-2013年河南省狂犬病流行特征分析

摘要:目的　描述河南省2005-2013年人狂犬病疫情流行特征,提出防治对策。方法　收集狂犬病疫情资料和个案调查资料进行描述性分析。结果　2005-2013年河南省共报告狂犬病病例1 022例,年平均发病率为0.12/10万;至2007年达到高峰,之后一直保持在较高水平。全年皆有发病,8月份最多;病例主要分布在南阳、周口、商丘、驻马店、信阳、许昌6个市,其发病总和占全省的57.1%。男女性发病比例约为2.41∶1;40～60岁组报告最多,占总病例数的36.8%;职业以农民为主,占发病数的76.6%;主要伤人动物为犬类,以自家养的为主,流浪狗占36.7%,还有猫和其他动物伤人的报道,暴露后绝大部分人（67.2%）未处理伤口,规范处置仅有12.2%,疫苗使用率则更低（2.6%）。结论　9年来河南省人狂犬病例疫情在县区层面整体上有增多趋势,疫情有向全省扩散倾向。建议建立人犬联合监测系统,从源头上控制疫情的发生和进展。     

河南省1995～2009年艾滋病疫情分析

目的了解河南省艾滋病流行情况,为制定科学的防控措施提供依据。方法从中国疾病预防控制信息系统艾滋病综合防治信息系统中"历史卡片下载"处下载1995～2009年河南省累计报告HIV感染者和艾滋病患者数据库。描述历年报告HIV感染者和艾滋病患者的地区和人群分布特征。结果截至2009年底全省累计报告HIV感染者和艾滋病患者46187例,主要聚集在豫东南6个省辖市;男女比例2004～2008年基本一致,到2009年略有增大,为1.36︰1;年龄主要集中在20～49岁组,但60岁以上病例数由1995年的0.9%上升到2009年的7.8%;既往有偿采供血构成比从1995年的93.8%下降到2009年的30.0%;性传播构成比从1995年的2.7%上升到2009年的34.3%;婚外性传播病例所占性传播的比例由2006年的24.6%上升到2009年的51.2%。结论河南省艾滋病流行在既往有偿献血人群仍然占有相当比例,但性传播和婚外性传播病例已经占主要部分,艾滋病流行模式正在转向性传播为主。     

山东省乙型肝炎病毒感染相关疾病住院患者经济负担及影响因素分析

目的 探索2004 — 2016年贵州省乙肝发病的时空分布特征及规律,为制定和调整乙肝防控策略提供科学依据。 方法 运用ArcGIS 10.2、SatScan 9.6软件对2004 — 2010年、2011 — 2016年乙肝发病率进行空间自相关和时空扫描统计量分析。 结果 贵州省2004 — 2016年乙肝报告病例来源于法定报告传染病报告系统,2004 — 2016年贵州省乙肝发病呈空间自相关性,2004 — 2010年、2011 — 2016年全局Moran′s I系数分别为0.148 0和0.443 9（P < 0.05）,2004 — 2010年的高值 – 高值聚集区为遵义所辖的3个县（区）,2011 — 2016年为遵义、黔南、黔东南所辖 的8个县（区）。时空扫描结果显示,2004 — 2010年乙肝可能聚集区发生在2008 — 2009年,主要分布于黔北地区;2011 — 2016年乙肝可能聚集区主要发生在2011年,分布于黔北、黔南、黔东南地区。 结论 贵州省乙肝发病总体呈下降趋势,有时空聚集性,其可能聚集区覆盖范围在扩大且呈现从黔北向黔南、黔东南等地区扩展的趋势。     

河南省2004-2010年斑疹伤寒的流行特征分析

目的了解河南省2004-2010年斑疹伤寒的流行状况及规律,为制定防控策略和措施提供科学依据。方法应用描述性流行病学方法和圆形分布法对河南省2004-2010年斑疹伤寒病例特征进行分析。结果河南省2004-2010年共报告斑疹伤寒病例172例,累积发病率0.1822/10万。2010年发病率最低,为0.0116/10万,2008年最高,为0.0385/10万,不同年份发病率差异有统计学意义(χ2=17.71,P<0.05)。各年病例均以散发为主,无暴发疫情及死亡病例报告。病例主要集中在豫中和豫北地区,7-9月为发病高峰期,10～49岁年龄组高发,以农民和学生为主。结论河南省斑疹伤寒发病以散发为主,应加强以灭鼠、灭虱、灭蚤、环境卫生整治及宿主动物监测为主的综合性防制措施,以有效控制疫情。     

湖南省2009年狂犬病监测分析

目的分析湖南省2009年狂犬病监测资料,评价预防处置效果,为预防和控制狂犬病提供依据。方法根据《湖南省狂犬病监测实施方案》,收集全省狂犬病监测资料进行流行病学分析。结果 2009年共报告狂犬病200例,发病率为0.31/10万。Ⅱ级、Ⅲ级暴露者占98.0%,伤口未处理者达65.5%,病例均无暴露前免疫史,暴露后只有13.0%注射了狂犬疫苗,133例Ⅲ级暴露者仅9.77%联合应用了抗狂犬免疫球蛋白或血清。狂犬病门诊监测中,湖南全省共报告267 133例暴露者,Ⅱ、Ⅲ级暴露者占85.60%。暴露者中有94.59%在预防门诊接受伤口处理,97.62%暴露后全程接种了疫苗,Ⅲ级暴露者中42.47%注射了抗狂犬免疫球蛋白或血清。伤人动物主要是犬,全省犬密度为6.309只/100人,兽用疫苗接种率为47.78%,犬只狂犬病毒感染率是0.56%。结论犬密度较高、犬群有较高的感染率,兽用疫苗接种率较低,群众防治意识不强以及暴露后未能得到规范处理是目前狂犬病高发的主要相关因素。加强犬只＂管、免、灭＂,规范暴露后伤口的规范处理,是遏制狂犬病高发行之有效的综合措施。     

集中度结合圆分布法对河南省2010年手足口病发病时间聚集性的分析

目的 分析河南省2010年手足口病发病时间的聚集性,探讨集中度和圆分布法的应用.方法 应用集中度结合圆分布法对河南省2010年手足口病发病时间数据进行分析.结果 2010年手足口病发病时间集中度M值为0.595.圆分布法平均角(α)对应日期即手足口病集中发病倾向时间为5月11日,5月11日前发病数占全年49.65％,5月11日及以后发病数占全年50.35％.发病时间的68.28％可信区间为3月11日～7月10日,此时间段实际发病数占全年病例总数的74.15％.平均角雷氏检验P＜0.01.结论 2010年河南省手足口病发病具有较强季节性,流行高峰期为3上旬～7月上旬,集中发病倾向时间为5月中上旬.     

河南省艾滋病高发区县级卫生人力资源投入情况分析

目的:了解河南省艾滋病高发区县级卫生人力资源投入情况。方法:选择河南省艾滋病高发区7个县(区),通过问卷调查,对其艾滋病防治的人力资源投入数量、专兼职人员基本情况构成、平均每个工作日用于艾滋病防治的工作时间进行分析。结果:河南省艾滋病高发区县级卫生人力资源投入数量大;专兼职人员职称构成不合理;专兼职人员平均每个工作日用于艾滋病防治的工作时间较长。结论:须优化艾滋病高发区县卫生人力资源的投入结构,以适应当前及以后的艾滋病控制需求。     

2007～2009年山东省疾病预防控制机构人力资源状况调查

[目的]了解山东省疾控机构人力资源状况,进一步加强全省各级疾控机构人力资源的开发利用。[方法]2010年,对山东省省、市、县三级疾病预防控制机构2007～2009年人力资源情况进行调查。[结果]2007～2009年,山东省省级疾病预防控制机构人员编制未满,市级人员编制略有超编;县级编制人数与现有人员总数均有下降,但仍然超编。全省疾病预防控制机构人员中,30岁以下者所占比例,2007～2009年分别为14.29%、14.18%、18.93%;省级为16.43%～21.18%,市级为15.31%～15.96%,县级为13.39%～13.99%。本科及以上学历者所占比例,2007～2009年分别为24.84%、27.43%、30.47%,3年平均省、市、县级分别为59.72%、46.69%、21.92%;高级和中级职称者所占比例,2007～2009年分别为51.12%、51.58%、53.17%,3年平均省、市、县级分别为64.15%、59.41%、49.76%。[结论]山东省疾控机构人员数量有所控制,学历水平有较大提高,但年龄结构有老龄化趋势,职称结构不尽合理。