经皮穿刺锁骨下动脉腔内成形术

目的：评价经皮穿刺锁骨下动脉腔内成形术的效果及安全性。方法：对76例锁骨下动脉严重狭窄或完全闭塞的患者行经皮经腔血管成形术（PTA）。所有患者均有椎基底动脉和（或）上肢动脉供血不足症状。术前DSA证实锁骨下动脉狭窄69例,完全闭塞7例。行单纯球囊扩张术68例,置入支架8例。结果：PTA术后所有患者症状均消失或明显减轻。DSA、经颅多普勒超声（TCD）显示45例患者锁骨下动脉窃血被纠正,有3例出现并发症（2例穿刺部位假性动脉瘤形成,1例术中一过性眩晕暧间恢复）。经4-35个月的随访（平均29个月）,发生再狭窄3例。结论：PTA治疗锁骨下动脉严重狭窄或完全闭塞是有效和安全的,并发症低于手术治疗。     

Percutaneous transluminal angioplasty of crural arteries

The authors dilated 103 stenosed crural arteries in 71 patients. Primary success was defined as traversing and reducing the lesion to a residual stenosis of less than 30%. This was achieved in 96% of cases. Complications included one vessel rupture and one occluding intimal flap, which were treated by the vascular surgeon with bypass and venous patch, respectively. One hematoma at the puncture site was treated surgically because of its size. With modern materials such as steerable guide wires and low-profile balloon catheters, dilation of crural arteries has become safe. Until now, the indications for percutaneous transluminal angioplasty (PTA) of crural arteries have been limited to Fontaine stages III and IV disease. The authors believe that the indications for PTA in Fontaine stage IIb disease are justified, especially if intervention improves outflow after a more proximal recanalizing procedure is performed.     

Percutaneous transluminal angioplasty of proximal subclavian artery occlusions

Percutaneous transluminal angioplasty (PTA) is a well-established treatment for patients with subclavian artery stenosis and brachial or cerebral symptoms. Its efficacy for treatment of subclavian occlusions, however, is not yet established. We attempted to recanalize the subclavian artery in 46 patients with proximal subclavian artery occlusion and were successful in 38 (83%). In two patients, residual stenosis, and in five patients, thrombotic material on the arterial wall required subsequent implantation of a self-expandable stent. Two additional patients were left with residual stenoses because stents were not available at that time. There were no cerebral or brachial complications. During a mean follow-up of 33 months, occlusion recurred in one patient after 3 months and stenosis recurred in five.     

Percutaneous transluminal angioplasty for treatment of subclavian steal

Twenty-two patients with subclavian steal were treated with percutaneous transluminal angioplasty (PTA). Fifteen had unilateral stenosis of the subclavian artery, one had severe stenosis on the left and total occlusion on the right, five had total subclavian occlusion on the left, and one had total occlusion of the innominate artery. All subclavian stenoses as well as the occluded innominate artery were successfully dilated, resulting in correction of subclavian steal; however, attempts to recanalize the totally occluded subclavian arteries failed. No restenosis of successfully treated arteries was observed during 5 years of follow-up. The authors recommend PTA as the treatment of choice for subclavian steal due to severe stenosis; however, total occlusion requires bypass surgery.     

Percutaneous transluminal angioplasty of the subclavian arteries: long-term results in 52 patients.

We studied the long-term results of percutaneous transluminal angioplasty of the subclavian artery in treating stenosis (43 patients) or occlusion (nine patients). In all 52 patients, the blood pressure before treatment in the arm on the involved side was at least 30 mm Hg lower than that in the opposite arm. Thirty-nine patients (75%) had symptoms of vertebrobasilar insufficiency (dizziness, blurred vision, ataxia). Angioplasty was successful in 40 (93%) of 43 patients with stenosis and in five (56%) of nine patients with occlusion. In the successfully treated patients, follow-up angiograms showed absence of narrowing greater than 30% stenosis, and the blood pressure in the treated arm equaled that in the opposite arm. The patients were followed up for 6-48 months (mean, 29 months). During this time, the blood pressure in the treated arm remained normal in 41 (91%) of 45 patients. The symptoms of vertebrobasilar insufficiency subsided in 28 (72%) of 39 patients. These results suggest that percutaneous transluminal angioplasty is useful for treating subclavian artery stenosis or occlusion.     

Percutaneous transluminal angioplasty of crural arteries.

In 91 patients suffering from peripheral arterial occlusive disease (Fontaine stage IIb-IV) 125 percutaneous transluminal angioplasties (PTA) of crural arteries were performed. Eighty-six of the dilatations were done in combination with a recanalization procedure (PTA, laser angioplasty, fibrinolysis) of a femoropopliteal obstruction in order to improve outflow. PTA was performed with 5 F balloon catheters 2.5 to 4 mm in diameter in combination with steerable guide wires. A primary technical success was achieved in 41 of 42 (97.6%) vessels with a single stenosis, in 64 of 68 (94.1%) vessels with 2 or more stenoses, and 9 of 15 (60%) vessels with total occlusions (overall primary success rate 91.2%). Complications included spasm (n = 3), thrombosis (n = 2), peripheral embolization (n = 2), and dissection (n = 1). None of the complications required surgical intervention. After PTA, accumulative patency rate of 71% at 2 years and 64.2% at 3 years was achieved. These results demonstrated that PTA of crural arteries is a safe procedure with an excellent primary success rate and satisfying long-term results. Thus we believe that even arterial occlusive disease in the clinical stage Fontaine IIb should be accepted as an indication for crural PTA. Furthermore, crural PTA should be used to improve reduced peripheral outflow after femoropopliteal PTA.     

Percutaneous transluminal angioplasty of tibial arteries for limb salvage

Percutaneous transluminal balloon angioplasty (PTA) was performed in 17 tibial arteries with an average cross-sectional area stenosis of 92% (range 75–99%) in 13 patients (14 limbs) for limb salvage. In 4 of 14 lower extremities, PTA of femoropopliteal arteries was also performed. Technical success with 50% or less residual stenosis was achieved in all 17 tibial vessels. At approximately 2 months after PTA, clinical improvement had occurred in 10 of 14 limbs; no patient was made worse. Most recent follow-up (mean 19 months, range 8–34 months) revealed continued satisfactory clinical success with no further vascular intervention in 9 of these 10 limbs (one patient died). Short segmental stenoses, residual stenoses less than 40% following PTA, and absence of diabetes or gangrene appear to be predictors of favorable clinical outcomes. Our results suggest that PTA of focal tibial stenosis is an effective and safe treatment modality in properly selected patients and that wider use of PTA may be justified.     

Percutaneous transluminal angioplasty of the subclavian and axillary arteries: initial results and long term follow-up.

The early and long term outcomes of 25 subclavian and axillary angioplasties in a series of 19 patients treated at one centre over a period of 10 years were assessed. The eventual outcome was long lasting improvement in most cases. Two of 25 PTAs were technical failures as defined as > 30% residual stenosis. Twenty-three of 25 PTAs were technical successes: 17 of these were first procedures, one was a repeat after an initial failure, two were repeats for restenosis and three were for separate new lesions. Clinically, 13 of the 19 patients were asymptomatic at long term follow-up. Four had only occasional, mild symptoms (in one of those they were due to shoulder arthropathy). Two patients had technically successful dilatations but developed problems with arterial occlusion distally which in one patient required amputation of that limb.     

Percutaneous transluminal angioplasty: iliac and deep femoral arteries

Percutaneous transluminal angioplasty of the iliac and deep femoral vessels appears to be successfully performed by experienced arteriographers, and the early and 2 year patency and clinical results are very encouraging. The technique requires detailed imaging systems and selective catheter technique acquired by experience in dealing with diseased arteries. The preliminary results and techniques using balloon dilatation catheters are presented.     

Percutaneous transluminal angioplasty for total occlusion of middle cerebral arteries

Although it is controversial whether total occlusions of intracranial arteries can safely be opened by angioplasty, we treated six patients with total occlusions of the middle cerebral artery by percutaneous transluminal cerebral angioplasty (PTCBA) in the chronic stage after a stroke, on average 10 weeks. We successfully opened four total occlusions less than 3 months old, while two total occlusions more than 3 months old could not be opened. No complications occurred. Even in the chronic stage, PTCBA for total occlusion of intracranial arteries can be done safely. Received: 8 September 1995 Accepted: 26 February 1996     

Percutaneous transluminal angioplasty of the iliac arteries: 66 experiences

Sixty-six iliac arteries in 45 patients, 25 male and 20 female, were treated with percutaneous transluminal angioplasty (PTA) for atherosclerotic occlusive disease. Of 103 lesions dilated, 51 were in common iliac and 51 in external iliac arteries. While iliac artery disease was the primary lesion in 18 patients, eight of whom had total occlusion, 27 patients had additional femoropopliteal disease. An overall primary success rate of 84% in dilatation of the stenotic lesions, and 33% in recanalization of totally occluded iliac arteries was achieved. In 12 patients, a prescheduled aortic bifurcation graft was cancelled. In one patient, in addition to recanalization of the occluded common iliac artery, the stenotic distal aorta was also successfully dilated. Angioplasty was unsuccessful in 12 patients. There were only three severe complications requiring surgical assistance. To date, less than 2 years, there has been a patency rate of 100%. Transluminal angioplasty is the treatment of choice for single stenotic lesions of the iliac arteries. Lack of calcification is not an absolute guarantee of success, but a favorable factor.     

Percutaneous transluminal angioplasty of the subclavian artery: Early and late results

Percutaneous transluminal angioplasty of 23 subclavian arteries was attempted in 22 patients. Dilatation was successful in 3 of 4 right subclavian artery stenoses and 18 of 19 left subclavian artery stenoses. The primary clinical indication was posterior fossa ischemia in 11 patients, upper limb ischemia in 14 and both symptoms in 6. In 2 patients, dilatation of an asymptomatic high-degree left subclavian artery stenosis was performed before coronary artery bypass surgery using the internal mammary artery. Eighteen patients on follow-up over 6–60 months (mean 25 months) are free of symptoms with equivalent systolic blood pressures in both arms. Three patients showed relapse of the stenosis after 8, 12, and 15 months; one was successfully treated with a second dilatation. Complications consisted of an occlusion at the left axillary artery puncture site and a distal embolus to a finger artery. Percutaneous transluminal angioplasty appears safe and efficient therapy for subclavian artery stenoses with excellent short- and long-term results.