Treatment with Hqi Bushen Koufuye Combined with Chemotherapy for Preventing Postoperative Metastasis of Stomach Cancer ——A Clinical Observation of 28 Cases

To study the effect of Yiqi Bushen Koufuye （益气补肾口服液 Oral Liquid for Invigorating Qi and Tonifying the Kidney） combined with chemotherapy on postoperative metastasis of stomach cancer. Methods： The 47 cases of postoperative stomach cancer with the syndrome of deficiency of both the spleen and kidney were divided randomly into the treatment group （28 cases）, and the control group （19 cases）. The control group was treated simply by chemotherapy; while the treatment group, was treated with Yiqi Bushen Koufuye in addition to chemotherapy. The effect was observed 12 months later on local relapse and distal metastasis, the life quality, peripheral hemogram, and immunologic function. Results： The rates of postoperative relapse and metastasis of the treatment group were obviously lower than those of the control group （P〈0.05）. The Karnofasky scores, peripheral hemogram and immunologic function of the treatment group were obviously improved in comparison with the control group （P〈0.01 or P〈0.05）. Conclusion： Yiqi Bushen Koufuye combined with chemotherapy is effective in preventing postoperative metastasis of stomach cancer, increasing sensitivity and decreasing toxins, and improving the life quality and immunologic function of the patient.     

Wrist–ankle acupuncture combined with pinching along the spine for children allergic rhinitis: A randomized controlled trial

Objective: To investigate the clinical effect of wrist–ankle acupuncture combined with pinching along the spine on allergic rhinitis(AR) in children.Methods: A total of 65 children with AR were collected from February 2017 through to December 2018 and they were randomly divided into a combined treatment group with wrist–ankle acupuncture, pinching along the spine and western medication(combined treatment group, 32 cases) and a western medication group(33 cases). In the western medication group, loratadine was prescribed for oral administration. In the combined treatment group, on the base of the medication as the western medication group,the wrist–ankle acupuncture was adopted in combination with pinching along the spine. Before and after treatment, the symptoms and physical signs were scored and the clinical effect was observed in the children of the two groups.Results: After the treatment and in the follow-up, the scores of the symptoms and physical signs in the combined treatment group were lower than those of the western medication group, indicating a statistical significance(all P 0.05). The total effective rate was 93.7% in the combined treatment group,which was higher than 63.63% in the western medication group, indicating a statistical significance(P 0.05).Conclusion: The combined treatment of wrist–ankle acupuncture combined with pinching along the spine and loratadine effectively relieves the clinical symptoms and the physical signs in AR children. The clinical effect of this combined treatment is better than the simple use of loratadine.     

Meta‑Analysis of Niaoduqing Granules Combined With RAAS System Blocker in the Treatment of Diabetic Nephropathy

To systematically evaluate the efficacy of urinary granules combined with RAAS system blockers in the treatment of diabetic nephropathy(DN). A meta-analysis of the data required in the literature in accordance with this study was performed using Rev Man 5.3 software. Fifteen randomized controlled trials were analyzed in the present study to evaluate the clinical effect of Niaoduqing-angiotensin converting enzyme inhibitors/angiotensin receptor blocker(ACEI/ARB) in DN patients. A total of 1063 patients were involved, including 538 patients receiving the combination treatment and 525 patients in the control group. The results showed that the clinical efficacy of Niaoduqing granule combined with ACEI/ARB was significantly better than of the control group(odds ratio = 2.92, 95% confidence interval [CI] 1.76–4.86). The treatment combined with Niaoduqing granule decreased the 24-h urinary protein quantitation(mean difference [MD] 0.71, 95% CI 0.28–1.14) and urine albumin excretion rate(UAER)(MD 41.13, 95% CI 26.66–55.59) levels. However, the combination group had no treatment advantage on reducing serumurea nitrogen(MD 0.86, 95% CI 0.05–1.68, P = 0.02) and fasting blood glucose(MD-0.03, 95% CI-0.15–0.09, P = 0.61). And there was no significance in adverse events between two groups(risk ratio = 2.34, 95% CI 0.69–7.95, P = 0.17). Niaoduqing granule-ACEI/ARB combination group maybe as safe as ACEI/ARB alone, and the combination played an advantage in improvement in total effective rate, reduction of 24-h urinary protein quantitation and UAER.     

Meta‑analysis of Clinical Efficacy of Traditional Chinese Medicine in the Treatment of Aplastic Anemia

Background: The “Diagnosis and Treatment Guidelines for Chinese Medicine Internal Common Diseases” issued by the Chinese Institute of traditional Chinese medicine (TCM) offers many methods for the treatment of aplastic anemia (AA). However, there is a lack of corresponding evidence. Objective: The study aimed to evaluate the clinical efficacy of TCM in the treatment of AA, and provide evidence for the development of guidelines for the diagnosis and treatment of AA using TCM. Methods: Data of randomized or semi?randomized control trials of AA treatments with TCM were retrieved, and the selected literature was scored using the Jadad scale. The data were extracted, and RevMan 5.2.6 software was used for the meta?analysis. Results: Two studies on the treatment of AA using Liuwei Dihuang pills combined with compound Zaofan pill were included. The results of the meta?analysis showed that there were no statistically significant differences in the efficacy between Liuwei Dihuang pills combined with compound Zaofan pill and androgen in the treatment of AA (P = 0.65). However, there were less adverse reactions, including liver damage and the hirsutism of women, with the former than the latter (P < 0.05). Other studies on the treatment of AA with TCM did not include reports from clinical trials. Conclusion: TCM had a certain curative effect when used to treat AA. However, the quality of the literature is generally low, and the sample size is small, which makes the validation of the results poor. Further high?quality studies are needed to provide high?level evidence.     

Effectiveness of redcore lotion in patients with vulvovaginal candidiasis: a systematic review and Meta-analysis

OBJECTIVE:To summarize and evaluate the effectiveness and safety of Redcore lotion on treating vulvovaginal candidiasis(VVC) using a systematic review and Meta-analysis of randomized controlled trials. METHODS:A systematic literature search was performed in five English and three Chinese electronic databases up to October 2019. Randomized controlled trials in the treatment for VVC were included; only studies which compared the effectiveness and safety of Redcore lotion plus miconazole with micon...     

Systematic Review and Meta-Analysis of Hugan Tablets(护肝片)in the Treatment of Drug-Induced Liver Injury

Objective:To systematically evaluate the efficacy and safety of Hugan Tablets(护肝片)in the treatment of drug-induced liver injury.Methods:Totally seven Chinese and English databases,including CNKI,Wanfang,VIP,CBM,PubMed,EMbase,Web of Science were searched for randomized controlled trials(RCTs)of Hugan Tablets(护肝片)for the treatment of drug-induced liver injury,which were published from the date of establishment to April 20,2019.The meta-analysis software RevMan 5.3 software and Excel were used to build a database into combine and analyze the studies that met the standards and to draw a forest plot.Results:Forty five RCTs were included with 7478 patients.The quality of included studies was uneven.Meta-analysis showed that the outcome index of liver injury rate was divided into seven subgroups.Hugan Tablets(护肝片)were used in the treatment of anti-tuberculosis drugs was superior to the conventional western medicine treatment group(RR=0.27,95%CI[0.22,0.33],P<0.00001).Which was also better than the without Hugan Tablets(护肝片)treatment group(RR=0.32,95%CI[0.20,0.52],P<0.00001).For the role of drug-induced liver injury in the treatment of type 2 diabetes,the Hugan Tablet+conventional treatment group is better than the conventional treatment group(RR=0.16,95%CI[0.03,0.88],P=0.03).The effect of drug-induced liver injury in the treatment of hypertension was superior to the conventional western medicine treatment group(RR=0.07,95%CI[0.03,0.14],P<0.00001).The effect of drug-induced liver injury during the treatment of hyperlipidemia was not statistically significant(RR=0.57,95%CI[0.33,1.00],P=0.05).There was no statistical difference between the two groups in the effect of drug-induced liver injury during the treatment of coronary heart disease(RR=0.09,95%CI[0.01,1.61],P=0.10).There was no significant difference between the two groups in the treatment of cerebral thrombosis for drug-induced liver injury(RR=0.11,95%CI[0.01,2.01],P=0.14).The effect of anti-hyperthyroidism on liver injury was better than that of conventional western medicine treatment group(RR=0.45,95%CI[0.25,0.82],P=0.009).Outcome index of total effective rate was divided into two subgroups.The effect of drug-induced liver injury caused by the type of drug was not mentioned was superior to the conventional western medicine treatment group(RR=0.78,95%CI[0.70,0.88],P<0.0001).There was no significant difference between the two groups in the liver injury caused by antipsychotic drugs(RR=0.97,95%CI[0.81,1.16],P=0.72).Conclusion:When used in the treatment of tuberculosis and psychiatric drug treatment,combineduse of Hugan Tablets(护肝片)can significantly reduce the incidence of drug-induced liver damage,and can significantly improve clinical symptoms caused by liver damage.In the treatment of hypertension,the addition of Hugan Tablets(护肝片)can significantly reduce the incidence of drug-induced liver injury,improving the safety of medication.In the treatment of drug-induced liver injury caused by which drug is not mentioned,Hugan Tablet has a therapeutic effect.Slight adverse reactions were reported,including rash,headache,palpitations,hypoglycemia,flushing,fatigue,nausea,bowel sounds,flatulence,diarrhea,and gastrointestinal discomfort.All studies reported minor adverse reactions that were well tolerated by patients and recovered without treatment after discontinuation.Oral administration of Hugan Tablets(护肝片)has positive effects on druginduced liver injury,but this conclusion still needs further evidences delete.It is necessary to adopt a larger sample,more design,and accord with the international standards to improve the quality of evidence.     

Clinical curative effect of electric acupuncture on acute cerebral in- farction： a randomized controlled multicenter trial

OBJECTIVE： To examine whether electric acupuncture can improve the daily life of patients with ischemic cerebral apoplexy at acute stage.METHODS： A stratified-block randomized controlled multicenter trial was designed for this study.Totally 340 patients with acute ischemic cerebral apoplexy were randomly divided into an electric acupuncture group and a control group. In the electric acupuncture group, 170 patients were treated with electric acupuncture and routine therapy, and170 patients in the control group with routine therapy alone. Major indexes for judging curative effect were Barthel index at 3- and 6- months follow-up visits and number of re-hospitalized patients. Mi-nor indexes for judging curative effect were change in the score for nervous dysfunction at 4and 12 weeks follow-up visits and number of patients persisting in rehabilitation treatment with acupuncture during follow-up visit.RESULTS： Baseline data at the time of case selection between the two groups were similar. The odds ratio（OR） was 0.92, and the 95% confidence interval（CI） was 0.49-1.73 in disabled rate and 0.73 and 0.51-1.05 in the number of re-hospitalized patients in the electric acupuncture group at 6-month follow up visit compared with the control group.There was no difference in the score for nervous dysfunction at the end of 12-week follow-up visit between the two groups. The score for nervous dysfunction at the end of 4-week treatment in the electric acupuncture group was significantly higher than that in the control group（P〈0.05）. The number of patients discharged from hospital who persisted in rehabilitation treatment with acupuncture in the acupuncture group was significantly higher than that in the control group.CONCLUSION： Using electric acupuncture to treat patients with acute ischemic cerebral apoplexy can effectively improve the nervous dysfunction scores after 4-week treatment and their ability to deal with daily life after 6-month follow-up visit. Systematic treatment with acupuncture may also reduc     

Thirty Cases of the Blood-Stasis Type Prolapse of Lumbar Intervertebral Disc Treated by Acupuncture at the Xi （cleft） Point plus Herbal Intervention Injection

Objective： To observe the cfinical therapeutic effects and explore the mechanism of acupuncture at the xi （cleft） points combined with herbal intervention injection for treatment of prolapse of the lumbar intervertebral disc with TCM symptoms and signs of blood stasis. Methods： The 60 cases in this series were randomly divided into a treatment group and a control group, 30 cases in each group. The patients in the treatment group were treated by acupuncture at Jiaji L4-S1, Waiqiu （GB 36）, Weizhong （BL 40） and Xiaxi （GB 43） plus intervention injection of Gegensu Zhusheye （葛根素注射液 Puerarin Injectio）. The patients of the control group were given the routine acupuncture combined with injection of Gegensu Zhusheye （葛根素注射液 Puerarin Injectio） into the Ashi points. The changes in interleukin-6 （IL-6） and hemodynamics were observed before and after treatment in both the two groups. Results： The total therapeutic effect in the treatment group was obviously better （P〈0.05） and the treatment course was obviously shorter than that of the control group （P〈0.01）. After the treatment, the total score, the visual analog scale （VAS） pain-evaluating score, and the score in straight-leg raising test were obviously improved in both the two groups, in which the improvement in the treatment group shown by the score in straight-leg raising test and the total score superior to that of the control group （P〈0.05）. The IL-6 level, red blood cell ratio, K value of blood sedimentation equation, and whole blood high shearing specific viscosity were improved in both the two groups, but the treatment group showed better improvement than that of the control group in the red blood cell ratio, K value of blood sedimentation, and IL-6 level （P〈0.05 or P〈0.01）. Conclusions： The treatment group was superior to the control group in improvement of the symptoms and signs, the daily life ability, and in pain alleviation. The mechanism is possibly related with the impro     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective： To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods： Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results： The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups （P〈0.05）. Conclusions： Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

Effects of Chinese herbs in children with Henoch-Schonlein purpura nephritis：a randomized controlled trial

OBJECTIVE： To research the curative effect of Chi- nese herbs for clearing away heat, promoting diure- sis, nourishing the kidney, and consolidating es- sence in children with Henoch-Schonlein purpura nephritis（HSPN） with internal accumulation of damp-toxin using randomized controlled observa- tions on large samples. To seek the mechanism of the therapy and its scope of indications. METHODS： Overall, 186 children with HSPN were randomly divided into two groups： treatment group（n=126） treated with Chinese herbs for clear- ing heat and promoting diuresis and a control group（n=60） treated with Western Medicine. The treatment was carried out for three courses of 4 weeks each. We recorded changes in patient urine routines, 24 h urinary protein, blood-coagulating series, immunoglobulin and T-cell subgroups, and improvements in main symptoms. We evaluated the alleviation of clinical symptoms and the im- provement of proteinuria, hematuria, and other lab-oratory test results. Finally, we analyzed the patient population suitable for this therapy according to the relationship between the grouping of patient body weight and curative effect. RESULTS： Damp-heat syndrome improved in the treatment group, with a significant difference in to- tal effective rate after a 4-week treatment（χ2= 13.5220, P=0.0002） and in curative rate after a 12-week treatment（χ2=6.3410, P=0.0118）, com- pared to those in the control group.The curative ef- fect in the treatment group was greater than that in the control group but there was no statistical dif- ference between the two groups. The curative ef- fect after a 4-week treatment of patients in the treatment group weighing 30 kg or less based on Traditional Chinese Medicine（TCM） signs and uri- nary protein was significantly greater than that in the control group. However, there was no statistical difference in the curative effect on urinary red cells and various indexes after a 12-week treatment be- tween the two groups. CONCLUSION： Therapy for clearing away heat, pro- moting diuresis, nourishing the kidney, and consoli- dating essence using TCM is effective in children with HSPN from internal accumulation of damp-toxin. The therapy is especially suitable for patients weighing 30 kg or less. The curative effect may be related to the improvement of immune function and blood-coagulation.     

Evaluation of individualized treatment of nonproliferative diabetic retinopathy:a multicenter,randomized,parallel-controlled study

OBJECTIVE: To evaluate the differences in the efficacy of stationary treatment and individualized treatment for patients with nonproliferative diabetic retinopathy(NPDR). METHODS: This study was a randomized, controlled, multicenter clinical trial. Participants with NPDR were randomized into the stationary treatment group or the individualized treatment group. The stationary treatment group was given the basic treatment and Qiming granules, and the individualized treatment group was given the ba...     

Xiyanping Injection in Treatment of Viral Pneumonia in Children: A Meta-analysis of Random Control Trials

Objective To evaluate the efficacy and safety of Xiyanping Injection in the treatment of viral pneumonia in children. Methods We searched several databases, including Pub Med, CNKI, VIP and Wanfang Data(January— June, 2014). The references of all selected studies were also retrieved to collect the relevantly randomized controlled trials(RCTs) on Xiyanping Injection for viral pneumonia in children. Two authors screened the literatures in accordance with the inclusive criteria, extracted the data and assessed the methodological quality of the included studies. We used Rev Man 5.2 software for meta-analysis. Results Meta-analysis on the 10 included RCTs showed that the effective rates of defervescing and vanishing of the rashes and cough in the Xiyanping Injection group were better than those in the Ribavirin Injection group. There was no significant difference between the two groups in the incidence of adverse drug reaction. Conclusion The existing research indicated that Xiyanping Injection is a secure and efficient scheme for viral pneumonia in children. Because of the poor quality of present researches, these results should be verified by strictly-designed and large-scale sample RCTs.     

Clinical Evaluation on Xiyanping Injection in the Treatment of Bronchopneumonia in Children Based on Meta‑Analysis

Objective: The aim of this study is to evaluate the effectiveness and safety of xiyanping injection (XYPI) in the treatment of children with bronchopneumonia. Methods:Asystematic and comprehensive search was conducted in the domestic and foreign electronic databases CNKI, SinoMed, VIP, WanFang DATA, PubMed, The Cochrane Library, Embase, Web of Science, Clinical?Trials.gov, and the search date ended on May 30, 2019. Inclusion criteria: (1) the types of studies included were randomized controlled trials; (2) the study participants were infants and children with a clear diagnosis of bronchopneumonia, without gender and ethnic restrictions; (3) the intervention test group was XYPI or the control group plus XYPI. The control group was routine treatment (RT) (basic treatment such as fever, cough and asthma, oxygen inhalation, anti?infection, maintaining water, electrolyte balance, etc.) or other Western medicine or RT + other Western medicine treatment. Except for XYPI, the two groups were consistent in intervention measures.According to the Cochrane Handbook, 5.1 evaluation standard and a meta?analysis of the final included studies was performed using RevMan 5.3 software. Results:Atotal of 57 studies were included, with a total sample size of 8454 cases, of which 4255 were in the experimental group and 4199 were in the control group. Meta?analysis results showed that (1) Total effective rate: XYPI group was better than the control group (relative risk [RRRT] = 1.25, 95% confidence interval [CI] [1.15, 1.36], P < 0.00001; RRRT + RBVI = 1.18, 95% CI [1.09, 1.29], P < 0.0001; RR antibiotic = 1.16, 95% CI [1.09, 1.24], P < 0.00001, RRRT + antibiotic = 1.22, 95% CI [1.16, 1.27], P < 0.00001); antipyretic time: XYPI group was better than the control group (mean difference [MDRT] = ?0.97, 95% CI [?1.17, ?0.76], P < 0.00001; MDRT + antibiotic = ?2.28, 95% CI [?2.88, ?1.67], P < 0.00001; MDRT + RBVI = ?1.51, 95% CI [?1.81, ?1.21], P < 0.00001; cough disappearing time: XYPI group was better than the control group (MDRT = ?1.37, 95% CI [?1.74, ?1.00], P < 0.00001; MDRT + antibiotic = ?1.71, 95% CI [?2.04, ?1.37], P < 0.00001; MDRT + RBVI = ?1.51, 95% CI [?2.15, ?0.86], P < 0.00001); disappearance time of lung rales: XYPI group was better than the control group (MDRT = ?1.11, 95% CI [?1.35, ?0.88], P < 0.00001; MDRT + RBVI = ?1.63, 95% CI [?2.23, ?1.03], P < 0.00001). The difference was statistically significant; (2) Of the 57 studies (a total of 8454 cases), 29 studies reported adverse reactions, of which 18 studies did not find adverse reactions, and 11 studies reported adverse reactions such as nausea, vomiting, and rash after medication in both groups. (3) The funnel chart indicated potential publication bias. Conclusion: Based on the existing clinical evidence, XYPI can have a certain effect on the treatment of children with bronchopneumonia, and it is not yet possible to conclude its safety evaluation. Moreover, due to the low quality of the included studies, this evidence is still used with cautious clinically.     

Clinical study on acupuncture in treating perimenopausal insomnia

Objective： To observe the clinical efficacy of acupuncture for insomnia in perimenopausal women. Methods： According to simple randomized controlled principle, sixty female patients with perimenopausal insomnia were randomized into two groups： 30 in the treatment group were intervened by acupuncture and the other 30 in the control group were intervened by taking sleeping pills. Therapeutic efficacies were compared between the two groups at the end of treatment. Results： The total effective rate was 100.0% in the treatment group versus 83.3% in the control group, and the difference was statistically significant （P〈0.05）. Conclusion： Acupuncture has better therapeutic efficacy than taking sleeping pills in treating perimenopausal insomnia.     

Observation on promoting resuscitation in the patients with coma of acute carbon monoxide poisoning by acupuncture combined with hyperbaric oxygen

Objective:To evaluate the effect of promoting resuscitation and the effect differences between acupuncture combined with hyperbaric oxygen therapy(HBOT)and simple HBOT in the patients with coma of acute carbon monoxide poisoning(ACMP).Methods:A total of 36 patients with ACMP coma were randomized into a simple HBOT group and acupuncture combined with HBOT group,18 cases in each one.In the simple HBOT group,HBOT was provided once a day for 2 weeks.In the acupuncture combined with HBOT group,acupuncture was provided during HBOT.The acupuncture was given before the patients were sent to the hyperbaric oxygen chamber and the needles were retained until the hyperbaric oxygen treatment was completed.The acupoints included B?ihuì(百会 GV 20),Shuǐgōu(水沟 GV 26),Sìshéncōng(四神聪 EX-HN1),Fēngchí(风池 GB20),Hégǔ(合谷 LI 4),Tàichōng(太冲 LR 3)and Yǒngquán(涌泉 KI 1).The needles were retained through the entire process of HBOT.Such combined treatment was given once a day for 2 weeks.Before the treatment,the score of Glasgow Coma Scale(GCS)was recorded,the levels of serum interleukin-6(IL-6),interleukin-8(IL-8)and brain-derived growth factor(BDNF)were tested and the time from unconsciousness to resuscitation was recorded of the two groups.After treatment,the levels of serum IL-6,IL-8 and BDNF were tested again and the clinical therapeutic effects were evaluated.Results:At last,there were 16 cases in the simple HBOT group and 17 cases in acupuncture combined with HBOT group got resuscitation.The time from unconsciousness to resuscitation was(5.17±1.10)h in the acupuncture combined with HBOT group,which was less than(6.83±2.73)h in the simple HBOT group,indicating the significant difference in statistic(P0.05).After treatment,the total effective rate was 94.4% in the acupuncture combined with HBOT group,which was higher than 88.9% in the simple HBOT group,indicating the significant difference in statistic(P0.05).After treatment,the levels of serum IL-6 and IL-8 were(29.72±3.49)and(67.17±7.61)pg/mL respectively in the acupuncture combined with HBOT group,which were lower as compared with those before treatment,indicating the significant differences in statistic(both P0.05).The level of IL-8 in the acupuncture combined with HBOT group was lower than(72.67±7.17)pg/mL in the simple HBOT group after treatment,indicating the significant difference in statistic(P0.05).After treatment,the level of BDNF was(14.78±3.90)pg/mL in the acupuncture combined with HBOT group,higher than the level before treatment,presenting the significant difference(P0.05),and higher than(12.93 ± 2.59)pg/mL in the simple HBOT group after treatment,presenting the significant difference in statistic(P0.05).Conclusion:Acupuncture combined with HBOT achieves the superior effect of promoting resuscitation and the clinical therapeutic effects as compared with the simple HBOT.Such combined treatment reduces the levels of serum IL-6 and IL-8,increases the level of serum BDNF in ACMP patients,as well as plays the active role in the prevention from delayed encephalopathy after acute carbon monoxide poisoning.     

Chondromalacia Patellae Treated by Warming Needle and Rehabilitation Training

Objective： To observe the effect of warming needle combined with rehabilitation training on chondromalacia patellae in a randomized controlled trial. Methods： The 92 cases were randomly divided into a treatment group treated by warming needle plus rehabilitation training （47 cases） and a control group treated by medication plus rehabilitation training （45 cases）, and the therapeutic effect was compared after 20 sessions. Results： The pain was relieved more obviously in the treatment group than in the control group （P〈0.05）, and the total effective rate was 91.8% and 71.1% respectively （P〈0.01）. Conclusion： Wanning needle plus rehabilitation training was superior in the therapeutic effect and duration of producing relief of pain to medication plus rehabilitation training in treating chondromalacia patellae.     

Combination of fire needle and filiform needle for frozen shoulder in different clinical stages

Objective:To observe the clinical efficacy of fire needle combined with filiform needle for different clinical stage frozen shoulders,and to choose the best treatment opportunity for clinical treatment of frozen shoulder.Methods:120 patients with frozen shoulders who met the inclusion criteria were numbered according to the visiting order.They were randomized into control group(60 cases)and treatment group(60 cases)according to the random number table.Both groups were treated with filiform needles once every other day and 3 times a week,and a course of treatment included 6 times and 2 courses were taken.The treatment group was treated by applying a fire needling point bloodletting on the local tender points once a week.Jiānyú(肩髃 LI 15),Jiānliáo(肩髎 TE 14),Jiānzhēn(肩贞 SI 9),Tiáokǒu(条口 ST 38),and local tender points were taken according to different meridian pains.The clinical efficacy of the frozen shoulder patients in the two groups in different clinical stages was compared.The evaluation indicators were scores of pain,joint activity range and activities of daily living,as well as clinical efficacy of traditional Chinese medicine.Results:After treatment,the total scores of hundred-mark five-grade in both groups were significantly higher than those before treatment,and the differences were statistically significant(Treatment group82.02 ± 14.23 vs 43.37 ± 22.10,Control group 66.80 ± 18.98 vs 42.67 ± 23.03,both P0.01),and the total score of the treatment group was significantly higher than the control group(P0.01).The hundred-mark five-grade assessment scores after treatment in the treatment group during the frozen stage were significantly higher than the control group(77.2± 14.40 vs 68.43 ± 16.94,P0.01);as to the clinical efficacy,the total effective rate of the treatment group was higher than the control group,and the difference was statistically significant(91.67% vs 76.67%,P0.01);The total effective rate of the control group in the acute stage and functional recovery stage was compared with the frozen stage,and the difference was statistically significant(100% vs 60%,P0.01),and there was no significant difference between each phase of the treatment group(P0.05).Conclusions:Single filiform therapy and the therapy of filiform needle combined with fire needle were effective in treating frozen shoulder patients,and the effect of the filiform needle combined with fire needle was significantly better than single filiform needle.The effect of fire needle combined with filiform needle on the frozen shoulder in frozen stage was significantly better than single filiform needle.     

Electroacupuncture in treating depression: A randomized controlled study

Objective: To observe the clinical efficacy of electroacupuncture in treating depression. Methods: By a randomized controlled study method, sixty patients with depression were randomized into an electroacupuncture group and a medication group, 30 in each. The electroacupuncture group was treated with electroacupuncture, and the medication group was orally administrated Paroxetine tablets. They were evaluated by using Hamilton Depression Scale (HAMD) before and after treatments and the safety was also assessed. Results: The total effective rate was 83.3% in the electroacupuncture group versus 60.0% in the medication group, and the difference was statistically significant (P<0.05). The electroacupuncture group was superior to the medication group in comparing the improvement of HAMD scores after treatment (P<0.05). Conclusion: Electroacupuncture is an effective approach in treating depression.     

CLINICAL OBSERVATION ON THE THERAPEUTIC EFFECT OF ACUPUNCTURE PLUS MANUAL REPOSITION FOR TREATMENT OF ACUTE LUMBAR VERTEBRAL ARTICULAR DYSKINESIA

Objective: To observe the therapeutic effect of acupuncture plus manual reposition for treatment of acute lumbar vertebral articular dyskinesia for choosing a better remedy. Methods: 66 cases of acute lumbar vertebral articular dyskinesia were randomly divided into acupuncture plus manual reposition group (treatment group, n= 33) and routine manual reposition group (control group, n = 33). Yaotong-point was punctured, when, the patient was asked to move his or her waist simultaneously. Results: After one session of treatment, of the two 33 cases in treatment and control groups, 28 (84.85%) and20 (60.61%) were cured, 4 (12.12%) and 9 (27.27%) were improved, and 1 (3.03%) and 4 (12.12%) failed in the treatment. The therapeutic effect of treatment group was significantly superior to that of control group ( P＜ 0.05). Conclusion: Acupuncture combined with manual reposition is apparently superior to simple routine manual reposition in relieving acute lumbar vertebral articular dyskinesia.     

Treatment of diabetic nephropathy with acupuncture

Objective to observe the clinical efficacy of acupuncture on diabetic nephropathy.Methods altogether 54 cases were randomly allocated into acupuncture group (30 cases) and control group of western medications (24 cases), the latter was treated with routine western medication, while the former was combined acupuncture based on routine western medication,and the treatment course of the two groups were both 30 days. Results the effect of treatment group was superior to the control group (P＜0.05). Conclusion acupuncture can improve symptoms of diabetic nephropathy, lower blood glucose, urine albumin, blood urine nitrogen,and creatinine and improve the function of kidney.