High-resolution ultrasound evaluation of extrinsic wrist ligaments in patients affected by rheumatoid arthritis

Objectives

To evaluate the ultrasound features of the extrinsic wrist ligaments in rheumatoid arthritis (RA) patients in comparison with healthy volunteers.

Methods

Twenty-one consecutive patients affected by RA (12 men, 9 women; mean age 57?±?14.6 years) were compared with 21 controls (12, 9; 54?±?12.1, respectively). Wrists were evaluated using ultrasound on both palmar and dorsal sides along each ligament, using carpal bones as references. The following ligaments were studied: radioscaphocapitate, radiolunotriquetral, palmar ulnolunate, palmar ulnotriquetral, dorsal radiotriquetral, dorsal ulnotriquetral, and radial collateral ligament. Ligament number and thickness were noted. Echotexture was rated as fibrillar, fragmented, or heterogeneous; the surface was rated as smooth or blurred.

Results

The number of palmar ulnolunate and palmar ulnotriquetral ligaments detected by ultrasound in patients was significantly lower than in controls (P?=?0.031 and P?=?0.037, respectively). All ligaments had significantly more fragmented or heterogeneous echotexture and blurred surface and were significantly thinner in patients than in controls (P?Conclusions Extrinsic wrist ligaments were less detectable and thinner in patients affected by RA compared with healthy volunteers matched for age and sex. Ligament thinning did not directly correlate with RA duration and clinical parameters.

Key Points

? Ultrasound is increasingly used to evaluate normal anatomy of extrinsic wrist ligaments. ? Extrinsic wrist ligaments are thinner in rheumatoid arthritis patients than in controls. ? Extrinsic wrist ligaments are less easy to detect in rheumatoid arthritis patients. ? Ligament thinning and detectability are not related to clinical parameters.     

高分辨力超声评价风湿性关节炎病人腕关节外部韧带的改变

摘要目的与健康志愿者相比,评估风湿性关节炎(rheumatoid arthritis,RA)病人腕关节外部韧带的超声特点。方法比较21例RA病人[男12例,女9例,平均年龄(57±14.6)岁]和21例健康志愿者[男12例,女9例,平均年龄(54±12.1)岁]。以腕骨作为参考,利用超声评价腕关节掌侧和背侧的韧带,包括桡舟头韧带、桡尺三角韧带、掌侧尺月韧带、掌侧尺三角韧带、背侧桡三角韧带、背侧尺三角韧带、桡侧副韧带及腓侧副韧带。     

Ultrasonographic evaluation of normal extrinsic and intrinsic carpal ligaments: preliminary experience

Objective To determine normal anatomy of extrinsic and intrinsic carpal ligaments at ultrasonography (US).Design and volunteers In the first part of the study, two musculoskeletal radiologists retrospectively reviewed in consensus the photographs of anatomic sections and dissections derived from 20 cadaveric wrists. This cadaveric study gave the two readers the opportunity to learn the anatomy and orientation of the various extrinsic and intrinsic carpal ligaments and, thus, to develop a US protocol to facilitate the recognition of each carpal ligament. In the second part of the study, these two radiologists prospectively and independently evaluated the visibility of extrinsic and intrinsic carpal ligaments in 30 wrists of volunteers, using the same US protocol.Results With regard to extrinsic carpal ligaments, the radioscaphocapitate ligament (partially visible, 38%; completely visible, 62%), the radiolunotriquetral ligament (partially visible, 27%; completely visible, 73%), the palmar ulnotriquetral ligament (partially visible, 12%; completely visible, 88%), and the dorsal radiotriquetral ligament (partially visible, 7%; completely visible, 93%) were visualized at US. The dorsal ulnotriquetral ligament (partially visible, 21%; completely visible, 74%), the ulnolunate ligament (partially visible, 5%; completely visible, 70%), and the radial collateral ligament (partially visible, 18%; completely visible, 12%) were more difficult to recognize. The radioscapholunate ligament was never seen. With regard to intrinsic carpal ligaments, the dorsal (partially visible, 11%; completely visible, 89%) and palmar (partially visible, 38%; completely visible, 62%) scaphotriquetral ligaments as well as the dorsal scapholunate ligament (partially visible, 3%; completely visible, 97%) were visualized at US. The dorsal lunotriquetral ligament (partially visible, 39%; completely visible, 61%) and the palmar scapholunate ligaments (partially visible, 12%; completely visible, 81%) were more difficult to recognize.Conclusion US may be helpful in identifying the major extrinsic and intrinsic carpal ligaments.     

腕关节韧带的解剖学研究

目的 了解腕关节韧带的解剖学特性。方法 成人腕关节标本34侧，其中32侧甲醛固定标本，另2侧为新鲜标本。解剖观察腕关节韧带的起止、走行、与关节囊的关系及韧带的毗邻；并测量其长度，每条韧带测量其中段宽度、厚度。结果 腕关节韧带包括掌侧韧带、背侧韧带以及内在骨问韧带3个部分。桡腕掌、背侧韧带长而宽，腕关节韧带掌侧较背侧强韧，同时数量也较多。腕骨间韧带短而厚。结论 腕关节相邻韧带多形成“V”结构，起着稳定腕骨和腕关节作用。     

Normal anatomy of the extrinsic capsular wrist ligaments by 3-T MRI and high-resolution ultrasonography

The anatomy of the extrinsic capsular wrist ligaments is complex. These ligaments are probably as important as the intrinsic interosseous ligaments for the maintenance of carpal stability. The extrinsic capsular wrist ligaments are frequently divided into dorsal, palmar, and collateral depending on their anatomical location. They have known origin and attachment sites with recognized anatomical variants. However, there is controversy in the literature related to their anatomy and nomenclature. In the past two decades, imaging has gained an important role in the evaluation of the extrinsic capsular wrist ligaments. Both 1.5-T magnetic resonance imaging (MRI) and magnetic resonance arthrography can provide good evaluation of the extrinsic capsular wrist ligaments; 3-T MRI with improved resolution provides better visualization of the same anatomical structures. Ultrasonography using high-resolution linear transducers allows good visualization of the extrinsic capsular wrist ligaments with results that are comparable with MRI. This article describes the normal anatomy of the dorsal, palmar, and collateral extrinsic capsular wrist ligaments on 3-T MRI and high-resolution ultrasonography.     

Dynamic high-resolution ultrasound of intrinsic and extrinsic ligaments of the wrist: How to make it simple

Wrist ligaments are crucial structures for the maintenance of carpal stability. They are classified into extrinsic ligaments, connecting the carpus with the forearm bones or distal radioulnar ligaments, and intrinsic ligaments, entirely situated within the carpus. Lesions of intrinsic and extrinsic ligaments of the wrist have been demonstrated to occur largely, mostly in patients with history of trauma and carpal instability, or rheumatoid arthritis. Ultrasound allows for rapid, cost-effective, non-invasive and dynamic evaluation of the wrist, and may represent a valuable diagnostic tool. Although promising results have been published, ultrasound of wrist ligaments is not performed in routine clinical practice, maybe due to its technical feasibility regarded as quite complex. This review article aims to enlighten readers about the normal sonographic appearance of intrinsic and extrinsic carpal ligaments, and describe a systematic approach for their sonographic assessment with detailed anatomic landmarks, dynamic manoeuvres and scanning technique.     

Pathology of extrinsic ligaments: a pictorial essay

The role of the extrinsic ligaments, together with the intrinsic ligaments, appears to be much more important than previously thought in the setting of carpal stability. The anatomy and pathology of the extrinsic wrist ligaments is complex. Magnetic resonance imaging (MRI) with thin slices is essential for visualization. This article describes the pathological appearance of the extrinsic palmar and dorsal radiocarpal and ulnocarpal ligaments on MRI, correlated with arthroscopy (performed by two skilled hand surgeons), clinical findings, and follow-up. High-resolution MRI, especially using isotropic three-dimensional sequences with orthogonal multiplanar reconstructions on 3T MR systems, allows detailed depiction of many of the extrinsic ligaments affected in carpal injuries. Recognition of ligament abnormalities is improved by intra-articular or intravenous injection of contrast before the examination. Both techniques may help to determine the precise localization, size, and extent of dorsal and palmar radiocarpal and ulnocarpal ligament lesions. Further experience with these techniques is needed to define the place of MRI in the management of traumatic wrist injuries.     

Extrinsic carpal ligaments: normal MR arthrographic appearance in cadavers

PURPOSE: To describe the normal magnetic resonance (MR) arthrographic anatomy of the major carpal ligaments (excluding scapholunate and lunotriquetral ligaments) and their osseous attachments by using standard imaging planes. MATERIALS AND METHODS: MR images of 22 wrists derived from fresh human cadaveric hands were obtained after tricompartmental arthrography. The MR arthrographic appearance of the carpal ligaments and their bone attachments were analyzed and correlated to those seen on anatomic sections. Two readers determined in consensus which was the best plane to observe the course and attachment sites for each ligament. They further analyzed the size and sites of attachment of these ligaments in two orthogonal planes chosen for optimal viewing. RESULTS: Each ligament was well seen as a hypointense linear structure with MR arthrography. The radioscaphocapitate, radiolunotriquetral, radioscapholunate, dorsal radiotriquetral, palmar scaphotriquetral, and dorsal scaphotriquetral ligaments were best evaluated in the transverse plane. The palmar and dorsal ulnotriquetral and ulnolunate ligaments were best visualized in the sagittal plane. The radial collateral ligament was best analyzed in the coronal plane. The attachment sites of all ligaments were best analyzed either in the transverse or sagittal planes. CONCLUSION: MR arthrography allows visualization of the carpal ligaments. Detailed knowledge of the normal appearance of these ligaments can serve as a baseline for future studies in which MR arthrography is used to characterize wrist instability.     

Sectional imaging anatomy: pelvic ring ligaments.

The purpose of this article is to describe the complex anatomy of the pelvic ligaments. It uses schematics to display 10 color-coded ligaments in relation to the bony architecture. This atlas and the accompanying summary of the classification of pelvic ligamentous injuries is designed to encourage the use of magnetic resonance imaging in cases of pelvic ring trauma.     

High-resolution ultrasound of peripheral neurogenic tumors

Peripheral nerve tumors are not frequent, but due to their association with a nerve they are somewhat special. They may be encountered incidentally during evaluation of a soft-tissue mass or when a nerve lesion is clinically suspected and the recognition of such a lesion and its differential diagnosis is key for successful therapy and patient prognosis. As sonography is often the first line modality in the work-up of a soft-tissue mass, the sonographer should be aware of the typical features of such lesions in order to arrive at the correct diagnosis, and this article tries to give an overview of the histological subtypes of peripheral nerve tumors and their sonographic characteristics.     

High-resolution MRI of the carpal tunnel. Anatomical correlations]

This anatomical study of the carpal tunnel compares magnetic resonance imaging sections and adult and fetal anatomical sections. The MRI studies were carried out in 12 normal controls. The use of an experimental high resolution module allows achieving as high a degree of spatial resolution as 0.13 mm2. The comparison of MR images with anatomical sections allows a very accurate analysis of the contents of the carpal tunnel, especially of the median nerve, of the flexor tendons and of the flexor retinaculum.     

Association between extrinsic and intrinsic carpal ligament injuries at MR arthrography and carpal instability at radiography: initial observations

PURPOSE: To retrospectively compare the presence or absence of carpal instability on radiographs with the findings of magnetic resonance (MR) arthrographic evaluation of intrinsic and extrinsic ligament tears in patients with chronic wrist pain. MATERIALS AND METHODS: The institutional review board approved this study and did not require informed consent. Signs of carpal instability were assessed on static and dynamic radiographs of the wrist obtained in 72 patients (24 female, 48 male; mean age, 36 years; age range, 14-59 years) with posttraumatic wrist pain. MR arthrography was subsequently performed. Two musculoskeletal radiologists independently analyzed the radiographs and MR images. Each intrinsic and extrinsic ligament was individually evaluated for the presence of a ligament tear. The extent of the tear also was recorded. Interobserver agreement regarding MR arthrographic findings was tested by calculating kappa statistics. Statistical comparison between radiography and MR arthrography was performed by using the Fisher exact test. RESULTS: Twenty-five triangular fibrocartilage complex, 18 (five partial, 13 complete) scapholunate ligament, and 25 (10 partial, 15 complete) lunotriquetral ligament tears were visualized. Twenty-two (all complete) extrinsic ligament tears were detected: two radial collateral ligament, 10 radioscaphocapitate ligament, and 10 radiolunotriquetral ligament tears. Interobserver agreement regarding intrinsic and extrinsic ligament tear detection at MR arthrography was excellent (kappa = 0.80). Nineteen patients had evidence of carpal instability on radiographs. Fourteen (52%) of 27 patients with at least one complete intrinsic lesion had no sign of carpal instability. On the other hand, the association of scapholunate ligament and/or lunotriquetral ligament and extrinsic ligament tears was significantly correlated (P < .001) with carpal instability at radiography. CONCLUSION: The presence or absence of carpal instability on radiographs depends on the association between intrinsic and extrinsic ligament tears-even partial ones-rather than on the presence of intrinsic ligament tears alone, even when the tears are complete.     

High-resolution MRI predicts steroid injection response in carpal tunnel syndrome patients

Objectives

To correlate median nerve T2 signal and shape at the carpal tunnel with steroid injection (SI) response in carpal tunnel syndrome (CTS) patients.

Methods

One hundred and sixty-three CTS wrists of 92 consecutive patients who were scheduled to undergo SI were prospectively evaluated with 3-T magnetic resonance imaging (MRI) and a nerve conduction study. All patients underwent axial high-resolution T2-weighted MRI (in-plane resolution of 0.25?×?0.25 mm). The CTS wrists were classified into three groups according to the nerve T2 signal and the flattening ratio at the hook of hamate level: group 1, high and oval; group 2, high and flat; group 3, low and flat. Clinical response to SI was evaluated at 6 months after injection.

Results

One hundred and thirteen of the 163 wrists (69.3 %) responded well to SI. The percentage of improvement was 81.7 % (49/60) in group 1, 69.9 % (51/73) in group 2, and 43.3 % (13/30) in group 3 (P?<?0.01). On stepwise logistic regression analysis high-resolution MRI was the only significant independent factor for SI response in CTS patients (P?<?0.01).

Conclusions

High-resolution MRI correlates well with SI response in CTS patients and seems useful for predicting SI response.

Key Points

? MRI may help determine appropriate care in carpal tunnel syndrome. ? MRI helps in therapeutic decision-making whenever steroid injection is considered. ? T2 signal decrease of the median nerve correlates with poor outcome. ? T2 signal decrease of median nerve may reflect fibrosis and amyloid deposition.     

High-resolution cranial ultrasound in the shaken-baby syndrome

With limited near-field resolution and accessible acoustic windows, sonography has not been advocated for assessing central nervous system injuries in the shaken-baby syndrome. Our purpose was to correlate high-resolution ultrasonographic characteristics of central nervous system injuries in whiplash injuries and the shaken-baby-syndrome with MRI and CT. Ultrasonographic images of 13 infants, aged 2–12 months, with whiplash or shaking cranial trauma were reviewed and compared with MRI in 10 and CT in 10. Five patients had serial ultrasonography and MRI or CT follow-up from 1 to 4 months after the initial injury. With ultrasonography we identified 20 subdural haematomas. MRI and CT in 15 of these showed that four were hyperechoic in the acute stage, three were mildly echogenic in the subacute stage, and that one subacute and seven chronic lesions were echo-free. Five patients had acute focal or diffuse echogenic cortical oedema which evolved into subacute subcortical hyperechoic haemorrhage in four, and well-defined chronic sonolucent cystic or noncystic encephalomalacia was seen at follow-up in two. Using ultrasonography we were unable to detect two posterior cranial fossa subdural haematomas or subarachnoid haemorrhage in the basal cisterns in three cases, but did show blood in the interhemispheric cistern and convexity sulci in two. Ultrasonography has limitations in demonstrating abnormalities remote from the high cerebral convexities but may be a useful adjunct to CT and MRI in monitoring the progression of central nervous system injuries in infants receiving intensive care. Received: 25 October 2000 Accepted: 25 October 2000