共查询到20条相似文献，搜索用时 15 毫秒
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G. Andrisani P. Soriani M. Manno M. Pizzicannella F. Pugliese M. Mutignani R. Naspetti L. Petruzziello F. Iacopini C. Grossi P. Lagoussis S. Vavassori F. Coppola A. La Terra S. Ghersi P. Cecinato G. De Nucci R. Salerno F.M. Di Matteo 《Digestive and liver disease》2019,51(3):375-381
Background and aim
Endoscopic full-thickness resection(EFTR) with FTRD® in colo-rectum may be useful for several indications.The aim was to assess its efficacy and safety.Material and methods
In this retrospective multicenter study 114 patients were screened; 110 (61M/49F, mean age 68?±?11?years, range 20–90) underwent EFTR using FTRD®. Indications were:residual/recurrent adenoma (39), incomplete resection at histology (R1 resection) (26), non-lifting lesion (12), adenoma involving the appendix (2) or diverticulum (2), subepithelial lesions(10), suspected T1 carcinoma (16), diagnostic resection (3). Technical success (TS: lesion reached and resected), R0 resection (negative lateral and deep margins),EFTR rate(all layers documented in the specimen) and safety have been evaluated.Results
TS was achieved in 94.4% of cases. EFTR was achieved in 91% with lateral and deep R0 resection in 90% and 92%. Mean size of specimens was 20?mm (range 6–42). In residual/recurrent adenomas, final analysis revealed: low-risk T1 (11), adenoma with low-grade dysplasia (LGD) (24) and high-grade dysplasia (HGD) (3), scar tissue (1). Histology reports of R1 resections were: adenoma with LGD (6), with HGD (1), low-risk (6) and high-risk (1) T1, scar tissue (12). Non-lifting lesions were diagnosed as: adenoma with HGD (3), low-risk (7) and high risk (2) T1. Adverse clinical events occurred in 12 patients (11%),while adverse technical events in11%. Three-months follow-up was available in 100 cases and residual disease was evident in only seven patients.Conclusions
EFTR using FTRD® seems to be a feasible, effective and safe technique for treating selected colo-rectal lesions. Comparative prospective studies are needed to confirm these promising results. 相似文献7.
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《Digestive and liver disease》2009,41(6):406-410
BackgroundThe newly designed over-the-scope clip (OTSC) seems to overcome several limitations of current clipping system, such as size and opening–closing force, allowing better control of gastric or colonic bleeding and/or deep wall defect or perforation.AimsThe aim of this retrospective analysis was to describe the new endoscopic device and evaluate our first clinical experience.Patients and methodsWe treated with the OTSC system 9 patients (range, 58–85 years; 6 men, 3 women) with bleeding and/or deep wall lesions of the GI tract. The OTSC system is composed of an application cap, which is mounted onto the distal tip of the endoscope and a connected releasing mechanism, installed on the handle of the scope. The rotation of the handle allows the release of the clip by a two tube sliding mechanism.ResultsAll applications resulted successful, i.e. haemostasis was achieved, and/or wall defects could be closed. No complication was observed that could be ascribed to the clip itself or to the technique.ConclusionsThe OTSC system is a new endoscopic tool for compression of large tissue areas and its indications are nonvaricose bleedings difficult to control and lesions or perforations of the GI tract. The initial clinical use of this clipping device proved to be efficient and effective. 相似文献
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Rafael Romero-Castro Mark Ellrichmann Carlos Ortiz-Moyano Jose Carlos Subtil-Inigo Felix Junquera-Florez Joan B. Gornals Alejandro Repiso-Ortega Juan Vila-Costas Francisco Marcos-Sanchez Miguel Muñoz-Navas Manuel Romero-Gomez Enric Brullet-Benedi Javier Romero-Vazquez Angel Caunedo-Alvarez Francisco Pellicer-Bautista Juan M. Herrerias-Gutierrez Annette Fritscher-Ravens 《Gastrointestinal endoscopy》2013
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