动物实验性急性心肌梗死大鼠在磁场作用下心肌的病理改变

目的本研究目的在于探讨磁场对急性心肌梗死（acute myocardial infraction，AMI）的保护治疗作用。方法将大鼠随机分为5组即：空白对照组、磁场对照组、AMI组、AMI药物（心得安）治疗组和AMI磁场治疗组。采用电子计算机影像分析系统形态计量方法测量计算心肌梗死面积测定，并对病理形态学观察。结果AMI磁场治疗组心肌梗死面积（infraction surface，IS）明显低于AMI组（P〈0．05）。通过光学显微镜对各组的观察表明：AMI组心肌梗死处肉芽组织增生，未见明显瘢痕形成，磁场治疗组心肌梗死处并可见部分瘢痕形成。结论磁场能减少AMI大鼠IS，有利于梗死处修复，对心肌具有保护作用，这也为磁场用于AMI的治疗提供了实验依据。     

低频电磁场对兔动脉平滑肌细胞增殖的抑制作用研究

目的:探讨不同场强、不同作用时间的低频电磁场对兔主动脉平滑肌细胞增殖的调控作用,以观察磁场是否能用于 PTCA支架后冠脉再狭窄的防治.方法:用含10%小牛血清的RPMI-1640培养液体外培养新西兰白兔的主动脉平滑肌细胞至3～7代,将含5％小牛血清的RPMI-1640培养液与动脉平滑肌细胞的混悬液100 靗加入96孔培养板中培养.按照实验分组,每日磁场作用一次,共二日.用MTT法检测动脉平滑肌细胞的增殖数量.结果:磁场作用时间大于10分钟时,20 mT、40 mT和60 mT磁场对动脉平滑肌细胞的增殖均有显著的抑制作用(P<0.05),其中作用时间为30分钟的40 mT磁场对动脉平滑肌细胞增殖的抑制作用最显著(P<0.001).结论:磁场对动脉平滑肌细胞增殖有显著的抑制作用,磁场的这种抑制作用具有强度敏感性、时间依赖性和空间距离性;磁场对PTCA支架后的冠脉再狭窄可能具有防治作用.     

37 nm非计量点氧化铁颗粒致HepG2细胞凋亡的研究

本研究以肝癌细胞HepG2细胞为对象,观察37 nm粒径磁性纳米非计量点氧化铁颗粒(FeOx)在外加磁场作用下对其增殖,凋亡的影响,旨在为FeOx用于治疗肝癌提供理论依据.     

37 nm非计量点氧化铁颗粒致HepG2细胞凋亡的研究

本研究以肝癌细胞HepG2细胞为对象,观察37 nm粒径磁性纳米非计量点氧化铁颗粒(FeOx)在外加磁场作用下对其增殖,凋亡的影响,旨在为FeOx用于治疗肝癌提供理论依据.     

37 nm非计量点氧化铁颗粒致HepG2细胞凋亡的研究

本研究以肝癌细胞HepG2细胞为对象,观察37 nm粒径磁性纳米非计量点氧化铁颗粒(FeOx)在外加磁场作用下对其增殖,凋亡的影响,旨在为FeOx用于治疗肝癌提供理论依据.     

磁场可以减轻疼痛的说法存在争议

过去曾有报道认为应用磁场可以减轻疼痛,并认为磁场可以加快作用部位局部组织的血液流动,加快氧气、营养物质、激素和缓解疼痛的内啡肽的运输。最近,英国的研究者在回顾了加拿大早前报道过的9个用含有磁场的产品与没有磁场或者磁场较弱的产品进行比较的研究后指出,目前尚没有确切的科学证据可以证明磁场真的可以减轻慢性疼痛。     

低频电磁场对兔动脉平滑肌细胞增殖的抑制作用研究

目的 :探讨不同场强、不同作用时间的低频电磁场对兔主动脉平滑肌细胞增殖的调控作用 ,以观察磁场是否能用于PTCA支架后冠脉再狭窄的防治。方法 :用含 10 %小牛血清的 RPMI- 16 40培养液体外培养新西兰白兔的主动脉平滑肌细胞至 3～ 7代 ,将含 5 %小牛血清的RPMI- 16 40培养液与动脉平滑肌细胞的混悬液 10 0μl加入96孔培养板中培养。按照实验分组 ,每日磁场作用一次 ,共二日。用 MTT法检测动脉平滑肌细胞的增殖数量。结果 :磁场作用时间大于 10分钟时 ,2 0 m T、40 m T和 6 0 m T磁场对动脉平滑肌细胞的增殖均有显著的抑制作用 (P<0 .0 5 ) ,其中作用时间为 30分钟的 40 m T磁场对动脉平滑肌细胞增殖的抑制作用最显著 (P<0 .0 0 1)。结论 :磁场对动脉平滑肌细胞增殖有显著的抑制作用 ,磁场的这种抑制作用具有强度敏感性、时间依赖性和空间距离性 ;磁场对 PTCA支架后的冠脉再狭窄可能具有防治作用     

恒磁场对人脐静脉内皮细胞活性及超微结构的影响

目的探讨恒磁场对血管内皮细胞活性、超微结构及凋亡的影响。方法将人脐静脉内皮细胞暴露于0.05、0.11、及5 mT恒磁场中,四唑盐比色法测定细胞增殖,采用透射电镜观察内皮细胞超微结构,流式细胞仪观测内皮细胞凋亡。结果0.05 mT恒磁场促进内皮细胞的增殖活性,0.1 mT恒磁场对细胞增殖无明显影响,1 mT、5mT恒磁场抑制细胞增殖。0.05 mT0、.1 mT1、mT恒磁场不引起细胞坏死,但1 mT恒磁场可引起部分细胞变性,5mT恒磁场不但引起细胞变性,还可以导致细胞坏死。0.05 mT、0.1 mT1、mT恒磁场没有引起细胞凋亡,5 mT恒磁场导致8.4%细胞凋亡。结论恒磁场对人脐静脉内皮细胞的生物学效应与磁感应强度有关,5 mT恒磁场对人脐静脉内皮细胞具有损害作用。     

磁场对AMI大鼠心肌ATP及血浆cAMP、cGMP的影响

目的探讨磁场对AM I的保护作用。方法将大鼠随机分为5组即:空白对照组、磁场对照组、AM I组、AM I药物(心得安)治疗组和AM I磁场治疗组。采用虫荧光素酶法及放射免疫技术法对实验性大鼠进行心肌ATP含量、及血浆cAMP、cGMP的测定。结果AM I磁场治疗组心肌ATP明显高于AM I组(P<0.01)与药物治疗组相近似。AM I的血浆cAMP、cGMP含量明显高于空白对照组(P<0.01)及磁场对照组,AM I磁场治疗组与药物治疗组明显低于AM I组(P<0.01)。结论磁场能降低AM I大鼠cAMP、cGMP的含量,增加心肌ATP含量,对心肌具有保护作用,这也为磁场用于AM I的治疗提供了实验依据。     

磁场对急性心肌梗死大鼠心肌丙二醛、三磷酸腺苷及红细胞超氧化物歧化酶含量的影响

目的探讨磁场对急性心肌梗死(AMI)的保护作用。方法将Wistar大鼠随机分为空白对照组、磁场对照组、AMI组、AMI药物(心得安)治疗组和AMI磁场治疗组。采用硫代巴比妥酸(TBA)法、虫荧光素酶法及黄嘌呤氧化酶法进行血浆和心肌丙二醛(MDA)、心肌三磷酸腺苷(ATP)含量及红细胞超氧化物歧化酶(SOD)活力的测定。结果AMI磁场治疗组血浆及心肌MDA明显低于AMI组(P<0.01),与药物治疗组相近似,低于空白对照组和磁场对照组;AMI磁场治疗组心肌ATP明显高于AMI组(P<0.01),与药物治疗组相近似。结论磁场能降低AMI大鼠血浆和心肌MDA的含量,增加心肌ATP含量和红细胞SOD活力,对心肌具有保护作用。     

Mixed Finite Element Formulation for Navier–Stokes Equations for Magnetic Effects on Biomagnetic Fluid in a Rectangular Channel

The article presents the mixed finite element formulation for examining the biomagnetic fluid dynamics as governed by the Navier–Stokes equation, coupled with energy and magnetic expressions. Both ferrohydrodynamics and magnetohydrodynamics describe the additional magnetic effects. For model discretization, the Galerkin weighted residual method was performed. Departing from a good agreement with existing findings, a biomagnetic flow (blood) in a straight rectangular conduit was then simulated in the presence of a spatially changing magnetic distribution. By virtue of negligible spatial variation influence from the magnetic field, the effects of Lorentz force were not presently considered. It was further found that the model accurately exhibits the formation and distribution of vortices, temperature, and skin friction located adjacent to and remotely from the source of magnetic load following a rise in the magnetic intensity.     

Magnetic Resonance Characterization of Porous Media Using Diffusion through Internal Magnetic Fields

When a porous material is inserted into a uniform magnetic field, spatially varying fields typically arise inside the pore space due to susceptibility contrast between the solid matrix and the surrounding fluid. As a result, direct measurement of the field variation may provide a unique opportunity to characterize the pore geometry. The sensitivity of nuclear magnetic resonance (NMR) to inhomogeneous field variations through their dephasing effects on diffusing spins is unique and powerful. Recent theoretical and experimental research sheds new light on how to utilize susceptibility-induced internal field gradients to quantitatively probe the microstructure of porous materials. This article reviews ongoing developments based on the stimulated echo-pulse sequence to extend the characterization of porous media using both spatially resolved and unresolved susceptibility-induced internal gradients that operate on a diffusing-spin ensemble.     

Magneto-Thermoelastic Response in an Unbounded Medium Containing a Spherical Hole via Multi-Time-Derivative Thermoelasticity Theories

This article introduces magneto-thermoelastic exchanges in an unbounded medium with a spherical cavity. A refined multi-time-derivative dual-phase-lag thermoelasticity model is applied for this reason. The surface of the spherical hole is considered traction-free and under both constant heating and external magnetic field. A generalized magneto-thermoelastic coupled solution is developed utilizing Laplace’s transform. The field variables are shown graphically and examined to demonstrate the impacts of the magnetic field, phase-lags, and other parameters on the field quantities. The present theory is examined to assess its validity including comparison with the existing literature.     

Power Batteries Health Monitoring: A Magnetic Imaging Method Based on Magnetoelectric Sensors

With the popularity of electric vehicles, the ever-increasing demand for high-capacity batteries highlights the need for monitoring the health status of batteries. In this article, we proposed a magnetic imaging technique (MIT) to investigate the health status of power batteries nondestructively. This technique is based on a magnetic sensor array, which consists of a 16-channel high-performance magnetoelectric sensor, and the noise equivalent magnetic induction (NEB) of each channel reaches 3–5 pT/Hz^1/2@10 Hz. The distribution of the magnetic field is imaged by scanning the magnetic field variation of different positions on the surface. Therefore, the areas of magnetic anomalies are identified by distinguishing different magnetic field abnormal results. and it may be possible to classify the battery failure, so as to put forward suggestions on the use of the battery. This magnetic imaging method expands the application field of this high-performance magnetoelectric sensor and contributes to the battery’s safety monitoring. Meanwhile, it may also act as an important role in other nondestructive testing fields.     

Evaluation of antianginal effects of running pulse magnetic field and drug therapy on the physical working capacity and hemodynamics in patients with stable angina pectoris]

The effects of the running pulse magnetic field, antianginal drug therapy and their combinations on the physical capacity were compared in 60 patients with Functional Classes I-III stable angina pectoris. Monotherapy with the running pulse magnetic field was found to produce an antianginal effect in patients with Functional Classes I-II angina pectoris, but the efficacy of drug therapy increased when antianginal drugs were used in combination with running pulse magnetic field in patients with severe angina.     

磁脉冲刺激技术在呼吸疾病中的应用

磁脉冲刺激技术是一种无痛、无创,能够有效地刺激呼吸性神经中枢、膈神经和躯干神经肌肉的新型手段,已经应用于呼吸科和急重症监护室,供医生判定患者呼吸中枢生理病理性改变,评定膈肌和身体功能状况以及进行呼吸肌康复训练评价.由于磁脉冲刺激技术在呼吸系统疾病的检测和治疗方面具有明显的优越性和实用性,因而有必要对其在呼吸疾病中的应用现状加以综合与评论.     

含肿瘤坏死因子聚碳酸酯磁性微球的制备及靶向治疗原发性肝癌的实验研究

目的 制备出一种新型的含TNF并具有强烈磁性反应的聚碳酸酯磁性微球,并进一步研究其体内对肝细胞癌的靶向治疗作用。方法 采用化学沉淀法制备Fe3O4超微磁粉,以聚5,5二甲基－三亚甲基碳酸酯－共－三亚甲基碳酸酯为膜材,在低温反应体系下,以人血清白蛋白为保护剂,采用改进的W／O／W复合溶剂挥发法制备含肿瘤坏死因子的聚碳酯磁性微球。研究了此微球制剂体外对肝癌细胞的细胞毒作用,并在外加磁场的作用下对人裸鼠肝癌模型进行了靶向治疗实验。结论 该磁性微球具有良好的磁响应性能,体外4000GS磁场下动作距离为26cm/min,体外对肝癌细胞bel-7402有较强的细胞毒作用,裸鼠人肝癌模型靶向治疗实验显示,在肿瘤部位5000GS条件下,静脉用药3次即有明显抑制肿瘤生长作用,其4周瘤重抑制率为55．46％,明显高于游离药物组（26．88％,P＜0．001）和无磁药物微球组（27．84％,P＜0．001）。结果 本实验为肝癌的生物靶向治疗提供了一种可能的新剂型,有较好的临床应用前景。     

温热磁场、音频电加中药热敷治疗退行性膝关节病100例疗效比较

目的 探讨温热磁场、音频电加中药热敷治疗退行性膝关节病的效果。方法 将100例有临床症状的膝关节病患者随机分温热磁场组与音频电加中药热敷组，观察两组患者治疗前后临床症状的改善情况，并进行对比。结果 温热磁场组与音频电加中药热敷组的显效率、有效率、总有效率分别为46％、48％、94％及42％、54％、96％，两组比较无显著性差异。结论 温热磁场与音频电加中药热敷治疗退行性膝关节病均有较好疗效，前者比后者操作更简便。     

The use of an alternating magnetic field in the resorption of postoperative joint effusion following anterior cruciate ligament reconstruction: A randomized double-blind controlled trial

ContextThere are no scientific reports unambiguously describing the efficacy of alternating magnetic field therapy in patients after anterior cruciate ligament (ACL) reconstruction in the early postoperative period.ObjectiveThis study aims to evaluate the efficacy of using an alternating magnetic field in the resorption of postoperative joint effusion in patients after ACL reconstruction.Study designA randomized, double-blind placebo-controlled study.SettingInpatients.ParticipantsForty patients were enrolled in the trial. However, the final study group consisted of 38 patients (28 men and 10 women) after ACL reconstruction who were randomly divided into an experimental group (19 patients) and a control group (19 patients).InterventionEach group received magnetic field therapy in the postoperative period, but only 1 apparatus emitted a magnetic field (the experimental group). Patients used the apparatus every day for 30 minutes for the next 11 days. The parameters in both devices were the same—3 mT and 10 Hz.Main outcome measuresThe measurement of the knee circumference and range of motion were made. The knee circumference measurement was performed before magnetic field therapy began and for 11 days after magnetic field treatment. The active knee range of motion was evaluated before and after magnetic field therapy was completed.ResultsThere were no statistically significant differences between the groups in the reduction of post-operative joint effusion or knee joint function.ConclusionIn patients after ACL reconstruction, in whom an alternating magnetic field was used to treat postoperative joint effusion, there were no beneficial effects on the analyzed variables compared to the control group.     

Giant Stress-Impedance Effect in CoFeNiMoBSi Alloy in Variation of Applied Magnetic Field

The article presents the stress impedance investigation of CoFeNiMoBSi alloy in variation of the applied magnetic field. In order to carry out the study, a specialized stand was developed that allows for loading the sample with stresses and simultaneous action of the DC (direct current) magnetizing field. The tests were carried out for as-cast and Joule annealed samples. The significant influence of the magnetizing field acting on the sample on the stress-impedance results was demonstrated and the dependence of the maximum impedance change in the stress-impedance effect was determined, depending on the field acting. The obtained results are important due to the potential use of the stress-impedance effect for the construction of stress sensors.