Gastrointestinal fluoroscopy: what are we still doing?

OBJECTIVE: We used Medicare data to quantify trends in gastrointestinal fluoroscopy volume. CONCLUSION: Although overall gastrointestinal fluoroscopy procedures continue to decline, the fall is not uniform. Nationwide Medicare data from 2001 to 2006 reveal that the volumes of barium enema and upper gastrointestinal studies suffered a steep drop, but the numbers of esophagograms and swallowing studies actually increased. These numbers highlight the challenge facing gastrointestinal fluoroscopy training and offer guidance for modifying curricula.     

Diagnosis of overtraining: what tools do we have?

The multitude of publications regarding overtraining syndrome (OTS or 'staleness') or the short-term 'over-reaching' and the severity of consequences for the athlete are in sharp contrast with the limited availability of valid diagnostic tools. Ergometric tests may reveal a decrement in sport-specific performance if they are maximal tests until exhaustion. Overtrained athletes usually present an impaired anaerobic lactacid performance and a reduced time-to-exhaustion in standardised high-intensity endurance exercise accompanied by a small decrease in the maximum heart rate. Lactate levels are also slightly lowered during submaximal performance and this results in a slightly increased anaerobic threshold. A reduced respiratory exchange ratio during exercise still deserves further investigation. A deterioration of the mood state and typical subjective complaints ('heavy legs', sleep disorders) represent sensitive markers, however, they may be manipulated. Although measurements at rest of selected blood markers such as urea, uric acid, ammonia, enzymes (creatine kinase activity) or hormones including the ratio between (free) serum testosterone and cortisol, may serve to reveal circumstances which, for the long term, impair the exercise performance, they are not useful in the diagnosis of established OTS. The nocturnal urinary catecholamine excretion and the decrease in the maximum exercise-induced rise in pituitary hormones, especially adrenocorticotropic hormone and growth hormone, and, to a lesser degree, in cortisol and free plasma catecholamines, often provide interesting diagnostic information, but hormone measurements are less suitable in practical application. From a critical review of the existing overtraining research it must be concluded that there has been little improvement in recent years in the tools available for the diagnosis of OTS.     

False-negative breast screening assessment: what lessons can we learn?

AIM: To review women who have had breast cancer diagnosed following previous assessment of a screen-detected mammographic abnormality in order to ascertain the frequency and characteristics of false-negative assessment. MATERIALS AND METHODS: The assessment process was reviewed in the study population of 28 women. This included the nature of the lesion recalled for assessment, additional mammography, clinical and ultrasound findings, and the results of fine needle aspiration cytology and needle histology. RESULTS: The frequency of false-negative assessment was approximately 0.56%. The median time between false-negative assessment and diagnosis of breast cancer was 33 months. The most common mammographic lesion resulting in false-negative assessment was micro-calcification seen in 12 cases (43%). Only five of these 12 cases had image-guided biopsy, the remainder were thought to be benign on magnification views. Other mammographic abnormalities were nine masses (32%), five architectural distortions (18%) and two asymmetric densities (7%). Of the 16 women with mammographic lesions other than micro-calcifications 10 had a normal ultrasound. CONCLUSION: Radiological interpretation of indeterminate micro-calcifications as benign or malignant is unreliable. An isolated cluster of micro-calcification requires image-guided core biopsy with representative micro-calcification obtained on specimen radiography. Further mammography done at assessment, particularly paddle compression views, should be carefully analysed to ensure areas of architectural distortion have truly resolved. If one imaging modality shows a significant abnormality and another does not the cases must be managed on the basis of the abnormal finding. Burrell, H.C.et al. (2001). Clinical Radiology56, 385-388.     

Helmet use: what message are we sending to patients?

INTRODUCTION: Multiple studies have demonstrated that the use of helmets by helicopter personnel saves lives and reduces morbidity. However, papers continue to cite potential adverse reaction from patients and the public as a justification for air medical personnel not wearing the helmets. PURPOSE: This study was conducted to determine how patients transported by helicopter react to helmets worn by air medical personnel. METHODS: Fifty-one adult patients with a Glasgow Coma Scale score of 15 were surveyed regarding their reaction to helmet use by air medical personnel. RESULTS: While the respondents had various concerns about the aircraft and flying, none had a negative reaction to the helmet use. CONCLUSION: Helmet use does not have a negative effect on patients, and such a putative effect should not be used to justify the avoidance of by air medical personnel.     

The ear in fetal MRI: what can we really see?

Introduction  

The aim of this study was to investigate the ability to depict the components of the ear on brain-oriented fetal MRI studies.     

Rehabilitation in cardiac patients:what do we know about training modalities?

This article discusses the effects of training in cardiac rehabilitation and describes the influence of various training modalities on the evolution of exercise capacity in cardiac patients. Both home- and hospital-based studies are analysed separately. From the collected studies, a very heterogeneous character of the content of the rehabilitation programmes appears. Direct comparison of the effects of the training programmes on exercise capacity remains difficult. Baseline factors for predicting a better training outcome are: low exercise capacity and peripheral oxygen extraction; presence of hibernating myocardium; high myocardial perfusion; low degree of coronary vessel occlusion; working status; and improved feelings of wellbeing. The increased work capacity as a result of rehabilitation is associated with: an increased volume density of skeletal muscle mitochondria; peripheral muscular vasodilatory capacity; cardiac output and a decreased left ventricular end-diastolic pressure; depletion of muscular phosphocreatine levels; and degree of restenosis. Home- and hospital-based interventions induce comparable training effects. More research is needed concerning the training modalities in cardiac rehabilitation. There is an influence of weekly training frequency and programme duration on the training outcome. A higher training frequency and/or duration might induce greater training effects. The evolution of the anaerobic threshold is sensitive to the training intensity and inclusion of strength training, which remains to be established for maximal exercise capacity. However, insufficient information is available on the influence of training session duration on the evolution of exercise capacity.     

The randomized trials of breast cancer screening: what have we learned?

Eight randomized controlled trials of mammography screening have been conducted to date. In addition to evaluating the efficacy of screening with an experimental design, the trials provided investigators with access to information about breast cancers much earlier in their development than had previously been available. The trials of mammographic screening provide conclusive evidence that the policy of offering screening is associated with a significant and substantial reduction in breast cancer mortality.