产后康复按摩对促进产妇身心健康的影响

目的 探讨促进产妇身心健康的有效方法.方法 将400例初产妇分为实验组和对照组各200例.对照组接受产后常规护理,实验组在此基础上加用产后康复按摩.比较两组产妇产后24h出血量、恶露量、排尿情况、泌乳量、子宫复旧情况、睡眠情况及产后抑郁发牛率等.结果 实验组24h出血量、恶露量、产后抑郁发生率明显少于对照组,排尿情况、泌乳量、子宫复旧情况和睡眠情况明显好于对照组,差异均有统计学意义.结论 产后康复按摩可明显改善产妇的整体康复水平,有利于促进产妇身心健康.     

康复治疗仪联合盆底训练对初产妇产后康复及生活质量的影响

目的探讨康复治疗仪联合盆底训练对初产妇产后康复及生活质量的影响。方法选取2014年2月~5月我科分娩的产妇100例为研究对象,采用随机数字表法分为观察组和对照组,每组50例。对照组产后采用常规护理。观察组在对照组的基础上采用康复治疗仪联合盆底训练。比较两组产后康复情况及生活质量。结果观察组产后宫缩痛评分、产后出血率低于对照组。宫缩痛持续时间、泌乳始动时间、子宫入骨盆时间、恶露时间短于对照组,两组比较有显著性差异(P0.05)。观察组生活质量评分、护理满意度高于对照组,两组比较有显著性差异(P0.05)。结论康复治疗仪联合盆底训练能够加快初产妇产后的泌乳和子宫复旧,减少疼痛,提高生活质量和护理满意度。     

妇产康复治疗仪在产妇产后康复护理中的应用效果

目的 探讨妇产康复治疗仪在产妇产后康复护理中的临床疗效.方法 将100例初产妇随机分为观察组和对照组,对照组产后常规护理,观察组在对照组的基础上使用妇产康复治疗仪,比较两组产后的恢复情况.结果 观察组产后宫缩痛持续时间、排尿时间、泌乳始动时间、恶露持续时间显著短于对照组,产后出血量显著少于对照组,宫缩痛评分、宫底高度低于对照组,睡眠质量好于对照组（P＜0.05）.观察组在生理、心理、社会环境、文化方面的舒适度均显著高于对照组,护理满意度显著高于对照组（P＜0.05）.结论 产妇康复治疗仪能显著促进产妇产后康复,减少并发症,提高住院舒适度和护理满意度.     

临床护理路径在初产妇中的应用

目的:探讨临床护理路径(CPN)在初产妇中的应用方法及效果。方法:将100例初产妇随机分为观察组和对照组各50例,对照组实施产妇常规护理模式,观察组实施CPN,比较两组护理效果。结果:两组产妇宫缩痛评分、泌乳始动时间、产后恶露时间、住院时间、母乳喂养率、产后生活质量评分、护理满意度比较差异均有统计学意义(P0.05)。结论:CPN能促进初产妇产后康复,改善生活质量,提高护理满意度。     

缩肛运动及延伸服务对产褥期产妇康复效果的影响

目的探讨缩肛运动及延伸服务对产褥期产妇产后康复效果的影响。方法本研究选取2017年6月—2018年10月在本院完成分娩的70例产妇作为研究对象,依据完全随机方式将其分成对照组和观察组,每组各35例;对照组实施常规产后护理,观察组在常规产后护理的基础上增加延伸服务以及缩肛运动治疗;对比两组产妇的康复效果及满意度。结果护理后,观察组产褥期泌乳情况明显优于对照组,差异有统计学意义(P 0.05);观察组产褥期泌乳情况满意度明显高于对照组,差异有统计学意义(P 0.05);观察组产后恶露消失时间早于对照组,差异有统计学意义(P 0.05)。结论延伸服务以及缩肛运动治疗对产褥期产妇的康复效果极为显著,能够有效缩短产妇产后恶露的消失时间,帮助产妇提升泌乳量,提高产妇对泌乳情况的满意度,值得在临床大力推广。     

产前家属培训对初产妇产后机体恢复的作用

目的：探讨产前家属培训对初产妇产后机体恢复的作用。方法选取我院初产妇及其家属102例,遵照随机分配的方式分为对照组和观察组,每组51例。对照组产妇产后接受常规的产后护理干预,观察组产妇在常规的产后护理基础上再对产前家属进行培训。比较两组产妇中不同分娩方式者产后自主排尿时间、恶露持续时间、泌乳时间及宫底下降高度。结果观察组产妇中顺产、剖宫产、产后自主排尿时间、恶露持续时间、泌乳时间及宫底下降高度均显著优于对照组（均P＜0.05）。结论产前家属培训对初产妇产后机体恢复的影响较大,更有助于产妇各方面的尽早康复。     

穴位按摩联合中药热熨对初产妇产后母乳喂养率及产后康复的影响

目的:探讨穴位按摩联合中药热熨对初产妇产后母乳喂养率及产后康复的影响。方法:2016年6月~2017年6月选取在本院建立分娩档案的220例初产妇,根据随机数字表将患者等分为对照组及观察组,对照组产后给予常规性乳房护理;观察组产后行乳房穴位按摩联合中药热熨。比较两组产妇产后24,48,72 h及42 d母乳喂养率、泌乳量及产妇产后康复情况。结果:观察组产后24,48,72 h及42 d母乳喂养率及泌乳量评分均高于对照组(P0.05)。观察组产妇乳房疼痛评分、肿胀评分低于对照组,而恶露消退时间、子宫复旧时间短于对照组(P0.05)。结论:穴位按摩配合中药热熨可促进初产妇产后泌乳,减轻产妇乳房胀痛,提高母乳喂养率,并有利于产妇产后康复。     

母乳喂养宣教对产妇产后情况的影响分析

目的：了解通过母乳喂养宣教后,产妇泌乳量及产后自身恢复的影响情况。方法：选择近2a在我院分娩的100例初产妇,将她们随机平均分成宣教组和对照组进行对比。结果：宣教组产妇的泌乳量,产后身体恢复情况各项指标明显优于对照组,两组比较差异有统计学意义（P〈0．01）。结论：产妇通过母乳喂养可使泌乳量增加,缩短浆液性恶露消失的时间,促其产后自身的恢复。     

综合护理干预对产后并发症的预防作用及对康复的影响

目的研究综合护理干预对产后并发症的预防作用及对康复的影响。方法收集该院妇产科收治的78例健康初产妇,按照随机数字表法分为对照组和观察组,各39例。对照组产后给予产褥期常规护理,观察组在对照组基础上给予健康宣教、乳房及子宫按摩、产后形体康复锻炼等综合护理干预。产后护理5d后观察两组并发症发生情况,泌乳始动时间、恶露量及子宫底高度,比较产妇产后焦虑自评量表(SAS)评分、抑郁自评量表(SDS)评分和生活质量(SF-36)评分。结果护理后观察组乳房胀痛、肌肉酸痛、排尿异常发生率低于对照组,差异均有统计学意义(P0.05)。观察组产后康复较好,泌乳始动时间、恶露量、子宫底高度优于对照组,差异均有统计学意义(P0.05)。观察组SAS、SDS评分低于对照组,SF-36评分高于对照组,差异均有统计学意义(P0.05)。结论产后给予早期综合护理干预有利于降低产妇并发症发生风险,促进产后泌乳、子宫恢复和减轻焦虑、抑郁情绪,有利于产后康复,提高生活质量。     

拉玛泽减痛分娩法对高龄产妇负性情绪及母婴结局的影响

目的:探讨拉玛泽呼吸减痛分娩法对高龄产妇负性情绪及母婴结局的影响。方法:将2008年8月~2014年1月建卡产检的400例高龄初产妇随机分为观察组和对照组各200例,对照组实施产科常规护理,观察组在常规护理基础上实施产前拉玛泽疼痛分娩法。比较两组产妇心理状况、分娩疼痛程度、Apgar评分、产程、剖宫产率、产后出血、泌乳量、血性恶露持续时间。结果:观察组产妇干预后SAS、SDS评分明显低于对照组干预后(P0.05);观察组产妇疼痛程度以0~I级为主,与对照组比较显著降低,且Apgar评分7分的比例显著升高(P0.05);观察组产妇剖宫产率、产后出血率较对照组显著降低,且各产程时间、血性恶露持续时间显著减少,产后泌乳量显著增加(P0.05)。结论:拉玛泽呼吸减痛分娩法的实施对于改善产妇负性情绪,减轻分娩疼痛,缩短产程,降低剖宫产率具有良好的临床效果,值得在产科临床中推广应用。     

NO and HNO donors,nitrones, and nitroxides: Past,present, and future

The biological effects attributed to nitric oxide (^?NO) and nitroxyl (HNO) have been extensively studied, propelling their array of putative clinical applications beyond cardiovascular disorders toward other age‐related diseases, like cancer and neurodegenerative diseases. In this context, the unique properties and reactivity of the N‐O bond enabled the development of several classes of compounds with potential clinical interest, among which ^?NO and HNO donors, nitrones, and nitroxides are of particular importance. Although primarily studied for their application as cardioprotective agents and/or molecular probes for radical detection, continuous efforts have unveiled a wide range of pharmacological activities and, ultimately, therapeutic applications. These efforts are of particular significance for diseases in which oxidative stress plays a key pathogenic role, as shown by a growing volume of in vitro and in vivo preclinical data. Although in its early stages, these efforts may provide valuable guidelines for the development of new and effective N‐O‐based drugs for age‐related disorders. In this report, we review recent advances in the chemistry of NO and HNO donors, nitrones, and nitroxides and discuss its pharmacological significance and potential therapeutic application.     

Genomics, Nutrition, Obesity, and Diabetes

PURPOSE: To present evidence of genetic and environmental interactions as they relate to nutrition, diabetes, and obesity. METHODS: A review of seminal literature related to genetics, obesity, and diabetes. FINDINGS: Multifactorial interactions are important in the development of nutrition-related disorders, but the challenge remains to explain how these interactions are expressed. Treating subpopulations of people might be important and useful to some extent at present, but in the future treating people of given genetic predispositions and other personal and environmental factors will have greater effects on quality-of-life indicators and life expectancies. CONCLUSIONS: Individualization coupled with multifactorial interactions will lead to new and more effective preventive and treatment modalities of nutrition-related disorders. With obesity and diabetes, genomics will bridge the traditional use of diet, exercise, and weight reduction with other environmental factors, ultimately leading to healthier lives.     

Platelets,thrombosis, coagulation,and atherosclerosis

When I first got the invitation to join a medical delegation going to Moldova, I thought for a moment that our destination was the fictional country in the old Marx Brothers movie Duck Soup. On further checking, it turns out that entertaining place was called Freedonia. I now know that Moldova is indeed a real country, bordered on the west by Romania and on the other three sides by the Ukraine. It is a proud country, rich with traditions, and its people are warm, giving, eager to learn ways to improve their healthcare system, and deeply appreciative of our attempts to help them in the task.     

Vomiting, diarrhea, constipation, and gastroenteritis

Diseases that cause vomiting, diarrhea, constipation, and gastroenteritis are major problems for populations worldwide. Patients, particularly infants, elderly, and immunocompromised individuals, may present at any point in a wide spectrum of disease states, underscoring the need for the clinician to treat these ailments aggressively. Several promising new treatment modalities, from oral rehydration solutions to antiemetic therapies, have been introduced over the past decade. Future directions include the use of probiotic agents and better tolerated rehydration solutions. Gastrointestinal disease will continue to be a focus worldwide in the search for better ways to cure illnesses associated with vomiting and diarrhea.     

Thoughts,images, worry,and anxiety

Recent models suggest that worry is primarily a verbal-linguistic process that enables images to be avoided and reduces somatic activation. Five-hundred and two subjects completed a questionnaire that assessed variables related to generalized anxiety disorder (GAD) criteria and also asked subjects to indicate the percentage of thoughts and images while worrying. Subjects were divided into excessive worriers (worry excessively about two or more topics more days than not for at least the last 6 months) and ordinary worriers (those who did not meet the previous criteria). As predicted, worry was reported as being composed predominantly of thoughts rather than images, and excessive worriers reported a significantly higher percentage of thoughts compared to ordinary worriers. The number of somatic symptoms was positively correlated with the percentage of images. This relationship was stronger among excessive worriers than ordinary worriers, specifically for autonomic hyperactivity symptoms. Further, in the excessive worry group only there was a significant negative correlation between the number of autonomic hyperactivity symptoms and the percentage of thoughts.This research was partially supported by grants from les Fonds de Recherche en Santé de Québec and the Medical Research Council of Canada. The study was completed while the first author was supported by the Medical Research Council of Canada.The authors gratefully acknowledge the assistance of France Blais for recruiting subjects, administering questionnaires, and entering data.     

Lipid messenger, diacylglycerol, and its regulator, diacylglycerol kinase, in cells, organs, and animals: history and perspective

Diacylglycerol kinase (DGK) metabolizes diacylglycerol (DG), a glycerolipid containing two acyl chains, to convert phosphatidic acid. DG is produced through phosphoinositide turnover within the membrane and is well known to act as a second messenger that modulates the activity of protein kinase C in the cellular signal transduction. Recent studies have revealed that DG also activates several proteins, including Ras guanine-nucleotide releasing protein and ion channels such as transient receptor potential proteins. Therefore, DGK is thought to participate in a number of signaling cascades by modulating levels of DG. Previous studies have disclosed that DGK is composed of a family of the isozymes, which differ in the structure, enzymological property, gene expression and localization, subcellular localization, and binding molecules. The present review focuses on the stories of phosphoinositide turnover and DG, including historical views, structural features, metabolism, and relevant cellular phenomena, together with the characteristics of DGK isozymes and the pathophysiological findings on animal studies using knockout mice and models for human diseases. Now it is being revealed that the structural and functional diversity and heterogeneity of and around DGK support the proper arrangement of the complex signal transduction machinery.