A verrucous carcinoma of the foot on an injection site: a case report

Verrucous carcinoma of the foot, also known as epithelioma cuniculatum, usually occurs on the inner aspect of the foot. It is a slow-growing variant of squamous cell cancer with a low metastatic potential. This case report presents a patient with a verrucous carcinoma of the foot who had been receiving long-term intralesional triamcinolone acetonide in that site for some steroid-responsive dermatosis, presumably lichen simplex chronicus.     

Lymphangiomyoma of the shoulder: an exceptional localisation. A case report

Lymphangioleiomyomatosis (LAM) is a rare condition usually occurring in young women of childbearing age. It is characterised by the presence of abnormal smooth muscle cells (LAM cells) in the lungs, lymph nodes, and/or other organs, with a few reports of isolated extrapulmonary cases. We report the case of a 26-yr-old female who presented with a painless shoulder mass. Ultrasonography, computed tomography and magnetic resonance imaging revealed an intermuscular mass with cystic and solid tissue components, measuring 6 cm x 4 cm. The mass was removed surgically after the diagnosis of LAM was made following tru-cut biopsy. This case corresponds to an exceptional localisation of LAM.     

An atypical mycobacterial infection of the shoulder

Mycobacterium malmoense is an acid-fast non-tuberculous organism that most commonly causes pulmonary infection. Extrapulmonary infection has also been reported. With an increased emphasis being placed on the clinical importance of this organism, especially within Europe, we report the first case of septic arthritis of the shoulder caused by this organism. We also highlight the importance of considering atypical mycobacterium infection in the differential diagnosis of shoulder infection and issues surrounding the management of this entity.     

疣状癌外科治疗探讨

目的：使用不同的手术方法治疗口腔、外阴及足跖部疣状癌。方法：2006年4月～2011年4月共收治25例疣状癌患者,分别采用皮肤移植、局部皮瓣修复、部分截趾及阴茎部分切除的方法治疗;从距离瘤体2cm左右的范围切除肿瘤,并从基底部将肿瘤完整切除,外阴生殖器部位疣状癌患者术后给予保留导尿。结果：采用不同的手术方法治疗了25例疣状癌,切口Ⅰ期愈合的23例,延期愈合1例,阴茎部分切除后尿道口狭窄者1例。结论：外科手术是治疗疣状癌的首选方法。     

阴茎疣状癌误诊分析

目的探讨阴茎鳞状细胞癌的特殊类型疣状癌误诊的原因和治疗方法。方法回顾分析9例阴茎疣状癌患者的诊治资料,患者平均年龄49岁,肿瘤呈菜花样生长。瘤体病现活检6例误诊。4例患者肿瘤局限于阴茎头者行肿瘤局部切除术,其余5例均行阴茎部分切除术。结果病理检查见肿瘤细胞分化良好,手术标本切缘未见肿瘤细胞。病理诊断均为“高分化鳞状细胞癌”。随访2-6年,平均3．8年,无1例肿瘤复发或转移。结论阴茎疣状癌细胞分化好,组织活检易误诊。由于其生物学行为以局部侵袭性生长为主,手术治疗预后好。     

阴茎疣状癌的诊治

目的探讨阴茎鳞状细胞癌的特殊类型疣状癌的诊断和治疗方法。方法回顾性分析8例阴茎疣状癌患者的诊治资料。患者平均年龄46岁。肿瘤均为菜花状、外生型，最大径2—6cm，局限于阴茎头5例，侵犯至冠状沟近侧3例。经活检病理诊断后，3例肿瘤侵犯冠状沟近侧者和1例位于阴茎头肿瘤较大者行阴茎部分切除术，4例局限于阴茎头者行肿瘤局部切除术。结果病理检查见肿瘤细胞分化好，标本切缘均阴性。1例肿瘤局部切除术者术后14个月阴茎残端复发，再行阴茎部分切除术，术后随访9年，无肿瘤复发或转移。其余7例术后随访4～13年，均无肿瘤复发或转移。肿瘤局部切除术者术后性生活较满意。结论阴茎疣状癌的生物学行为以局部侵袭性生长为主，很少发生区域性淋巴结转移或远处转移，采用恰当的治疗方法后患者预后好。     

The Buschke-Lowenstein tumour or verrucous carcinoma of the penis

The Buschke-Lowenstein tumour of the penis is a rare neoplasm of probable viral origin. It is locally destructive but does not appear to metastasize. The three cases reported illustrate the clinical features and the surgical treatment.     

阴茎疣状癌诊治分析

目的 探讨阴茎疣状癌的诊断和治疗方法.方法 回顾性分析10例阴茎疣状癌患者的诊治资料.根据肿瘤大小及位置不同,分别行不同方式手术处理,术后给予抗病毒药物辅助治疗.结果 病理检查见肿瘤细胞分化好,标本切缘均阴性.术后随访6个月～3年,未见局部复发与转移.10例均可站立位排尿、维持勃起并完成性生活.结论 阴茎疣状癌是低侵袭性的特殊类型鳞癌,细胞分化好,很少发生区域性淋巴结转移或远处转移,采用手术治疗,术后效果良好.     

Oral squamous cell carcinoma: an atypical presentation mimicking temporomandibular joint disorder

A 50-year-old female presented to a chiropractic clinic with left jaw pain consistent with temporomandibular joint disorder. Examination revealed a large ulcerated mass on the posterolateral margin of the tongue which was later diagnosed as squamous cell carcinoma. Squamous cell carcinoma is the most common of the oral cancers. These cancers are often detected late making treatment more complicated and reducing the chance of survival. In the early stages squamous cell carcinoma can be asymptomatic. Symptoms can be similar to that of temporomandibular joint disorder making examination of the patient's mouth important to rule out oral cancers. Oral cancers should be considered when patients present to a chiropractor with pain in the area of the temporomandibular joint. Risk factors such as chronic tobacco and alcohol use should raise concern in these patients. Suspicious lesions should be referred immediately for further investigation.     

阴茎疣状癌的临床病理特征及治疗

目的:探讨阴茎疣状癌的临床病理特征,提高对阴茎疣状癌的诊断和治疗水平。方法:回顾性分析18例阴茎疣状癌患者的临床资料。患者平均年龄52(35~66)岁,主要表现为阴茎肿物成菜花样,均伴有脓性分泌物,最大直径2.5~8.7 cm。巨大疣状癌侵犯至会阴1例(既往尖锐湿疣,阴茎肿物切除史),局限于阴茎头2例,侵犯至冠状沟4例(均有包皮过长史,1例合并阴茎头炎),侵犯至全阴茎11例(其中4例既往包皮、阴茎肿物,2例合并包茎史)。2例肿瘤侵犯冠状沟近侧者和2例肿瘤位于阴茎头相对较小(3.5 cm)者行阴茎部分切除术,2例阴茎头部肿瘤较大(3.5 cm)者、11例累及全阴茎、1例累及会阴者行阴茎肿瘤根治术。结果:术后病理检查:18例均提示肿瘤细胞分化好,切缘呈阴性,上皮呈乳头状结构并过度角化伴增生,周围间质见淋巴细胞浸润,符合阴茎疣状癌病理特征。术后随访1~8年,平均3.8年,肿瘤均无复发。结论:阴茎疣状癌病理表现为局部侵袭性生长,很少有淋巴结或远处转移,治疗方法采用阴茎部分切除或阴茎肿瘤根治术,患者预后较好。     

Condylomata acuminata and verrucous carcinoma of the bladder: case report and literature review

Condylomata acuminata and verrucous carcinoma are 2 lesions rarely seen in the bladder. Condylomata of the bladder can be treated successfully by local therapy but underlying carcinoma must be considered if the lesion is extensive or progressive in nature. Vigorous biopsies of the base of the lesions are necessary to eliminate the possibility of malignancy. If verrucous carcinoma is found the patient should be treated surgically. A case of condylomata acuminata of the bladder undergoing malignant change to verrucous carcinoma is reported.     

阴茎疣状癌的临床诊断和治疗

目的 探讨阴茎疣状癌的诊断和治疗. 方法 回顾性分析6例阴茎疣状癌患者的诊治资料.患者平均年龄45岁.肿瘤均为菜花状、外生型,最大径2～6 cm,局限于阴茎头4例,侵犯至冠状沟近侧2例.3例在术前经病理活检确诊,另3例为术后病检证实.2例肿瘤侵犯冠状沟近侧者和2例位于阴茎头肿瘤较大者行阴茎部分切除术,1例局限于阴茎头与冠状沟之间者给予包皮环切术,1例局限于阴茎头者行肿瘤局部切除术. 结果 病理检查见肿瘤细胞分化好,标本切缘均阴性.6例术后随访2～4年,无肿瘤复发或转移. 结论 6例阴茎疣状癌以局部侵袭性生长为主,未发生区域性淋巴结转移或远处转移,选择手术方式合理,预后良好.     

Invasive verrucous carcinoma of urinary bladder treated by irradiation

A case of inoperable, invasive verrucous carcinoma of the urinary bladder treated by irradiation is presented. The incidence of anaplastic transformation of verrucous carcinoma after irradiation is lower and the coincidence of verrucous carcinoma and well-differentiated squamous carcinoma higher than is generally recognized. Radiation should be considered in inoperable cases. The pertinent literature is reviewed.     

Carcinoma of the male breast: difficulties of differential diagnosis in a case of bleeding atypical gynecomastia

Male breast cancer represents a sporadic oncological disease (0.2-1.5%), with a very rare incidence (200 times lower) compared to omologous condition in women. Low incidence, early metastasizing chances, due to particular anatomic structure of the male gland, offering a high invasiveness rate to surrounding tissues are responsible of a late diagnosis, for which an histopathological response in case of malignant suspect, should be mandatory as well as poor prognostic expectations, in case of lymphnodes positivity (5 year-survival, after radical mastectomy: 17-60%), which unfortunately accounts for 50% of the patients at diagnosis. The difference with the success obtained in the treatment of female breast cancer, is striking, caused by the absence of a standard therapy and, on the other hand, of any screening programs.     

The pathology of head and neck tumors: verrucous carcinoma,part 15

Verrucous squamous cell carcinoma is a distinctive clinicopathologic entity. The lesion's biologic activity places it between conventional (nonverrucous) carcinomas and nonautochthonous hyperplasias of squamous epithelium. The diagnosis of the lesion requires full communication and cooperation between surgeon and pathologist. Once the diagnosis is confirmed, the selection of surgery over radiotherapy should be based on the recorded effectiveness of each modality and not on the phenomenon of anaplastic transformation reported to follow radiotherapy.     

Doppler localisation of intrarenal vessels: an experimental study

The use of the Doppler probe to localise the intrarenal vessels was assessed in 15 dogs. This prevented the need for renal artery clamping and radial nephrotomies were placed in silent areas on the renal surface. Functional studies were performed post-operatively at 48 h and 1 month, using creatinine clearance, microfil casts and cast angiography. There was no significant loss of function when three or six radial nephrotomies were made and the Doppler accurately localised sites for nephrotomy between the intrarenal arteries and veins which were undamaged.