天麻熄风口服液治疗急性期脑梗死疗效观察及对血脂和血压的影响

目的观察天麻熄风口服液治疗急性期脑梗死的临床疗效及对患者血脂和血压影响。方法将181例急性期脑梗死患者随机分为2组。对照组90例予常规西医治疗,治疗组91例在对照组的基础上加用天麻熄风口服液治疗。2组均连续治疗2个疗程后观察比较患者治疗前后血脂指标[总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)]及血压(收缩压、舒张压)水平变化,并统计疗效。结果治疗组治疗后总有效率95.40%,对照组总有效率72.21%,2组总有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组。2组治疗后TC、TG、LDL-C、HDL-C及收缩压、舒张压水平与本组治疗前比较差异有统计学意义(P<0.05),且2组治疗后组间比较差异亦有统计学意义(P<0.05),治疗组改善明显。结论天麻熄风口服液能显著改善患者血脂水平和降低血压,促进脑梗死功能恢复,治疗急性期脑梗死临床疗效肯定。     

巨针巨刺法对脑梗死患者脑血流图、血液流变学和血脂的影响

目的:观察巨针巨刺对脑梗死患者脑血流图、血液流变学和血脂的作用及其机制.方法:将78例脑梗死患者随机分为巨针巨刺组44例与毫针巨刺组34例进行对比观察.结果:两组均能改善脑梗死患者脑血流图、血液流变学和血脂的多项指标参数,但巨针组优于毫针组(P<0.05).结论:两种刺法均有效,巨针法优于毫针法.     

Effect of warm joint needling plus rehabilitation on the balance function and quality of life of patients with spastic hemiplegia after ischemic cerebral stroke

Objective

To observe the effect of warm joint needling plus rehabilitation techniques on the balance function and quality of life (QOL) of patients with spastic hemiplegia after ischemic cerebral stroke.

Methods

Ninety patients with spastic hemiplegia after ischemic cerebral stroke were randomized into a rehabilitation group, a warm joint needling group and an observation group, with 30 cases in each group. The rehabilitation group was intervened by Bobath therapy, the warm joint needling group was treated with joint needling on the affected side plus warm needling, and the observation group was given the same rehabilitation treatment as the rehabilitation group together with the same warm joint needling as the warm joint needling group. The three groups were treated once another day, 1 month as a treatment course for 6 months. Before the treatment, and respectively after 2-week, 1-month, 3-month, and 6-month treatment, the modified Ashworth scale (MAS) was used to measure the anti-spasm ability of the lower limb, the Berg balance scale (BBS) was adopted to evaluate the balance function, and the stroke-specific quality of life scale (SS-QOL) was employed to estimate the QOL.

Results

After 3-month and 6-month treatment, the lower-limb MAS scores in the observation group were significantly better than those in the rehabilitation group and the warm joint needling group (all P<0.05). After 1-month, 3-month and 6-month treatment, the BBS scores in the observation group were significantly better than those in the rehabilitation group and the warm joint needling group (all P<0.05). After 2-week, 1-month, 3-month and 6-month treatment, the SS-QOL scores in the observation group were markedly better than those in the rehabilitation group and the warm joint needling group (all P<0.05).

Conclusion

Warm joint needling plus rehabilitation can effectively improve the lower‐limb spasticity state, balance function and QOL in patients with spastic hemiplegia after ischemic cerebral stroke.

     

针刺颅骨缝加药物治疗急性脑梗死患者的临床研究

目的:探讨提高治疗急性脑梗死(CI)疗效的最佳方法.方法:60例早期CI患者,随机分为A、B两组,B组采用CI早期常规药物治法,A组在B组治疗基础上加用颅针治疗.结果:A组治疗后神经功能较治疗前差异有非常显著性意义(P<0.01),血小板膜糖蛋白(GMP-140)较B组下降有显著性意义(P<0.05).结论:①颅针加药物改善临床神经功能,抑制血小板活化优于单纯药物治疗组.②CI早期,治疗前后神经功能缺损评分值与血浆GMP-140水平呈中度正相关,表明血浆GMP-140水平可作为CI患者病情轻重和预后的客观指标.     

脑栓通胶囊对脑梗死患者脑血流储备的影响

目的:探讨脑栓通胶囊对脑梗死患者脑血流储备的影响。方法:将90例脑梗死患者随机分两组,脑栓通组加用脑栓通口服。治疗前后记录患者NHISS评分,并检测大脑中动脉屏气的指数(BHI)。结果:两组患者治疗前后NIHSS评分无显著差异(P0.05)。治疗后BHI升高,与治疗前比较差异有统计学意义(P0.05),组间比较有显著性差异(P0.05)。结论:脑栓通可改善脑梗死患者脑血流储备能力。     

推拿结合温针治疗腰椎间盘突出症临床观察

目的:观察推拿结合温针治疗腰椎间盘突出症的疗效.方法:将90例腰椎间盘突出症患者随机分为两组,观察组45例,采用推拿结合温针治疗;对照组45例,采用单纯推拿治疗.结果:观察组的总有效率为88.9％,对照组的总有效率为75.6％,两组总有效率具有统计学差异(P＜0.01).结论:推拿结合温针治疗腰椎间盘突出症疗效优于单纯推拿手法治疗.     

Therapeutic observation of warm needling plus tuina for senile functional constipation

Objective： To observe the clinical efficacy of warm needling plus tuina in treating senile functional constipation. Methods： Ninety elderly patients with functional constipation were randomized into two groups. Forty-six patients in the treatment group were intervened by warm needling plus tuina; the other forty-four patients in the control group were intervened by San Huang tablet. Results： In the treatment group, 19 patients were cured, 24 cases showed improvement, 3 cases failed, and the total effective rate was 93.5%; in the control group, 16 patients were cured, 18 cases showed improvement, 10 cases failed, and the total effective rate was 77.3%. There was a significant difference in comparing the therapeutic efficacy（P〈0.05）, and the therapeutic efficacy of the treatment group was higher than that of the control group. Conclusion： Warm needling plus tuina can produce a higher therapeutic efficacy than taking San Huang tablet in treating senile functional constipation.     

温针灸联合透药疗法治疗薄型子宫内膜临床研究

目的:探讨温针灸联合透药疗法在薄型子宫内膜(TE)治疗中的临床价值。方法:106例TE肾虚证患者随机分为对照组和治疗组各53例,对照组口服戊酸雌二醇片加阴道用雌二醇片,治疗组在对照组基础上给予温针灸联合透药疗法治疗。比较两组治疗前后子宫内膜容受性、血液流变学、转化日性激素指标和妊娠结局。结果:治疗组子宫内膜厚度及形态均优于对照组(P<0.05); 治疗后两组血流搏动指数(PI)、血流阻力指数(RI)、血浆黏度均低于治疗前(P<0.05),红细胞变形指数高于治疗前(P<0.05); 治疗组PI、RI、血浆黏度低于对照组(P<0.05),红细胞变形指数高于对照组(P<0.05); 治疗组移植周期所占比例、临床妊娠率、胚胎种植率显著高于对照组(P<0.05)。结论:温针灸联合透药疗法可改善薄型子宫内膜患者的内膜容受性和冻融胚胎移植的妊娠结局。     

深刺风池穴对偏头痛患者脑血流动力学及血液流变学的影响

目的:探讨深刺风池穴对偏头痛患者脑血流动力学及血液流变学的影响。方法:本研究纳入偏头痛患者40例,分为深刺风池穴组(20例)和常规针刺风池穴组(20例),应用经颅多普勒检测治疗前后脑血流变化及血液流变仪检测治疗前后血流变学的改变。结果:深刺组有效率100%,常规针刺组有效率85%。两组治疗后大脑中动脉(MCA)、大脑前动脉(ACA)、大脑后动脉(PCA)及基底动脉(BA)血流量差异有显著性(P&lt;0.05),而两组比较治疗前后血液流变学指标差异无显著性(P&gt;0.05)。结论:深刺风池穴对偏头痛患者脑血管机能及脑血流变化可能有更好的调整作用。     

Therapeutic observation on swift needling with fire needle plus medication for herpes zoster

Objective： To discuss the effectiveness and safety of swift needling with fire needle plus medication in treating herpes zoster and the change of substance P. Methods： Seventy-nine patients with herpes zoster were selected and randomized into a fire-acupuncture group （41 cases） and a Western- medication group （38 cases）. The fire-acupuncture group was intervened by swift needling with fire needle, and simultaneously prescribed with Valaciclovir Hydrochloride tablets and Vitamin B1; the Western-medication group was by the same oral medicines alone. The therapeutic efficacies were evaluated afterwards. Results： The total effective rate was 95.1% in the fire-acupuncture group versus 89.5% in the Western-medication group, and the difference was statistically significant （P〈0.05）. After treatment, the concentration of substance P and visual analogue scale （VAS） score dropped significantly in both groups （both P〈0.05）; the inter-group differences were statistically significant （both P〈0.05）. Conclusion： Swift needling with fire needle plus medication has better therapeutic efficacy than medication alone in treating herpes zoster.     

Effect of governor vessel-regulating needling combined with rehabilitation training on the activities of daily living of patients with cerebral infarction

Objective

To observe the difference in efficacy between governor vessel-regulating needling and conventional acupuncture, and to summarize the clinical efficacy and application rules of governor vessel-regulating needling.

银杏达莫注射液对急性脑梗死患者脑血流及血管内皮功能的影响

目的探讨银杏达莫注射液(银杏总黄酮)对急性脑梗死患者脑血流及血管内皮功能的影响。方法 84例急性脑梗死患者随机分成银杏达莫注射液治疗组和对照组,每组42例。对照组采用常规方法治疗,治疗组在常规治疗的基础上静脉滴注银杏达莫注射液,连续14 d。比较两组患者治疗前后神经功能缺损程度评分、脑血流和血浆一氧化氮(NO)、人内皮素-1(ET-1)、组织纤溶酶原激活物(t-PA)、血浆纤溶酶原激活物抑制剂-1(PAI-1)水平的变化。结果经过14 d治疗后,治疗组和对照组神经功能缺损评分均显著下降,治疗组下降更加显著(P<0.05);治疗组和对照组的大脑中动脉(middle cerebral artery,MCA)、大脑前动脉(anterior cerebral antery,ACA)和大脑后动脉(posterior cerebral artery,PCA)平均血流速度均显著升高,治疗组MCA、ACA和PCA平均血流速度均高于对照组,其中MCA和PCA差异显著,有统计学意义(P<0.01和P<0.05);治疗组患者的NO和t-PA水平升高、ET-1和PAI降低,与对照组相比,NO和ET-1水平有显著性差异(P<0.01和P<0.01)。结论银杏达莫注射液联合常规治疗急性脑梗死,可明显改善急性脑梗死患者脑血流和血管内皮功能,有利于恢复瘫痪肢体的神经功能。     

Therapeutic effect of warm needling plus acupoint sticking therapy on primary dysmenorrhea due to cold-dampness retention

Objective

To observe the clinical efficacy of warm needling plus acupoint sticking therapy for primary dysmenorrhea.

Methods

A total of 60 eligible cases were randomly allocated into a treatment group (n=30) and a control group (n=30) according to their sequence of consultation. Patients in the treatment group were treated with warm needling combined with acupoint sticking therapy, whereas patients in the control group were treated with oral Ibuprofen (Fenbid) capsules. After two menstrual cycles, the visual analogue scale (VAS) score, COX menstrual symptom scale (CMSS) and clinical efficacy were compared between the two groups.

Results

After treatment, the VAS and CMSS scores were significantly reduced in both groups, indicating that both treatment protocols can remarkably alleviate pain. There was a between-group statistical difference in comparing the CMSS score (P<0.05), but no between-group statistical difference in the VAS score (P>0.05). However, the follow-up visit showed between-group statistical differences in comparing VOA and CMSS scores (both P<0.01). The clinical effect, relapse rate and long-term efficacy in the treatment group were better than those in the control group.

Conclusion

Warm needling plus acupoint sticking therapy is a simple but effective therapy for primary dysmenorrhea. In addition, it causes fewer cases with relapse.

     

参麻通络胶囊对脑梗死恢复期患者血液流变学及血脂变化的影响

目的观察参麻通络胶囊治疗脑梗死恢复期的临床疗效及对血液流变学和血脂指标的影响。方法将160脑梗死恢复期患者随机分为2组。对照组80例,予西医常规治疗;治疗组80例,在对照组治疗的基础上加用参麻通络胶囊口服。2组均治疗3个月为1个疗程,1个疗程后评定临床疗效。观察比较2组治疗前后血液流变学、血脂指标及神经功能缺损评分的变化。结果治疗组总有效率82.5%,对照组总有效率66.25%,2组总有效率比较差异有统计学意义（P〈0.05）,治疗组疗效优于对照组;2组治疗前后血液流变学、血脂指标及神经功能缺损评分变化比较差异均有统计学意义（P〈0.05）,且治疗组治疗后变化较对照组显著（P〈0.05）。结论参麻通络胶囊能有效改善脑梗死恢复期患者的血液流变学、血脂及神经功能缺损等指标,促进患者病情恢复,且安全无毒副作用。     

Observation on clinical efficacy of warm needling moxibustion plus Mulligan dynamic joint mobilization for cervical radiculopathy

Objective

To observe the clinical efficacy of warm needling moxibustion plus Mulligan dynamic joint mobilization for cervical radiculopathy.

Methods

A total of 60 cases with cervical radiculopathy were randomly divided into group A, group B and group C by random digital table, 20 cases in each group. The patients in three groups were treated with similar warm needling moxibustion. Group A only received warm needling moxibustion; group B was treated with warm needling moxibustion plus Mulligan dynamic joint mobilization; group C was treated with warm needling moxibustion plus cervical traction. Before the treatment and after 12 sessions of treatment, the patients in the three groups were assessed for score of pain and range of motion (ROM).

Results

By 12 sessions of the treatments, the scores of pain were obviously decreased in the three groups, with statistical significances (all P<0.05), and the pain scores of group B and group C were significantly different from the score of group A (both P<0.05). ROM of the neck was increased than before the treatment in the three groups, with statistical significances (all P<0.05), and the ROM of the neck of group B was significantly different from those of group A and group C (both P<0.05).

Conclusion

Warm needling moxibustion plus Mulligan dynamic joint mobilization can effectively improve the neck ROM and relieve pain in patients with cervical radiculopathy.

     

应用SPECT观察眼针对脑梗死患者脑血流的影响

目的:验证眼针穴区与脏腑功能相关性,为眼针疗法辨证取穴原则提供理论依据.方法:将60例脑梗死患者按照中医分型辨证取穴,主穴:上焦区、下焦区;配穴:风痰火亢型加肝区、肾区、脾区,风痰瘀阻型加肝区、脾区,痰热腑实型加胃区、大肠区,气虚血瘀型加心区、脾区,阴虚风动型加肝区、肾区.利用单光子发射型计算机断层扫描(SPECT),观察眼针治疗前后病灶局部脑血流量变化.结果:眼针前病变区与对侧相应区域的感兴趣区(ROI)摄取比值为0.74±0.12,眼针后为0.91±0.08,眼针前后差异有统计学意义(P＜0.05),眼针治疗后脑血流量明显增加.结论:眼针疗法辨证取穴可增加脑梗死患者局部脑血流量,改善脑缺血状态,从而证明眼针穴区与脏腑具有相关性.     

丽珠脑力隆胶囊对43例多发腔隙性脑梗塞患者血液流变学及血脂的影响

腔隙性脑梗塞是指由于累及脑内大动脉穿通支的原发性小动脉病引起的小的深部梗死部位主要位于基底节，特别是壳核、丘脑、内囊的白质及桥脑。2004—10—2005—10，笔者采用丽珠脑力隆治疗多发腔隙性脑梗塞43例，并观察其对血液流变性、血脂的影响，现报道如下。     

分期针刺治疗脑梗死的临床疗效对比研究

目的：比较分期针刺法与常规针刺法治疗脑梗死的临床疗效.方法：将60例符合纳入标准的病人随即分为治疗组（分期针刺）和对照组（常规针刺）各30例,比较治疗后病人肌力改善程度.结果：经4周治疗后,治疗组愈显率83.33%,优于对照组60%（P＜0.05）,差异有显著性意义.结论：分期针刺治疗脑梗死偏瘫疗效优于常规针刺法.     

补阳还五汤对脑梗塞恢复期血液流变学及血脂的影响

目的:观察补阳还五汤对脑梗塞恢复期血液流变学及血脂的影响。方法:将58例脑梗塞恢复期患者随机分为治疗组和对照组,对照组予常规西药治疗,治疗组常规西药治疗基础上加补阳还五汤治疗,3周后评定疗效。2组治疗前后分别测定血液流变学及血脂各项指标。结果:治疗组血液流变学各项指标与治疗前比较有明显改善(P<0.01),治疗组血脂与治疗前比较有明显改善(P<0.01);治疗组治疗后血液流变学及血脂各项指标与对照组比较均有显著性差异(P<0.05)。结论:补阳还五汤与西药结合可明显改善脑梗塞恢复期患者血液流变学及血脂各项指标,较单用西药常规治疗效果显著,两者比较有显著性差(P<0.05)。     

Randomized Controlled Trial on Mind-refreshing and Orifice-opening Needling Method and Cerebral Infarction

目的：观察醒脑开窍针法治疗脑梗死恢复期的，临床疗效。方法：600例脑梗死患者以病程分层随机，恢复期234例，随机分为治疗组116例，对照组118例。在西医常规治疗的基础上，治疗组采用醒脑开窍针刺；对照组采用传统针刺，均每日治疗1次，共治疗4星期。随访6个月。结果：两组患者基线资料可比性好，（P〉0．05）；治疗组疗效优于对照组（P〈0．05）。结论：醒脑开窍针剌是安全的，治疗脑梗死恢复期能够改善症状，减少致残，防止疾病进展，提高生活质量。