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1.

Objective

To observe the protective effect of acupuncture plus mild hypothermia on brain tissues in rats with cerebral ischemia-reperfusion injury (CIRI), and the influence on protein expression levels of phosphorylated Raf-1, MEK-2 and ERK1/2 in the mitogen-activated protein kinase (MAPK)/extracellular regulated protein kinases (ERK) pathway, and to explore the mechanism of acupuncture plus mild hypothermia therapy for the ischemic stroke.

Methods

Ninety Sprague-Dawley (SD) rats were randomly divided into a blank control group, a sham operation group, a model group, an acupuncture group, a mild hypothermia group and an acupuncture plus mild hypothermia group, 15 rats in each group. Except the rats in the blank control group, the remaining rats were used to prepare the middle cerebral artery occlusion (MCAO) models according to the modified occlusion method using lines, while only the occlusion lines were inserted without blocking the brain arteries of rats in the sham operation group. When the vital signs of rats were stable, rats in the blank control group did not receive any intervention; rats in the sham operation group and the model group received fastening without treatment; rats in the acupuncture group, the mild hypothermia group, and the acupuncture plus mild hypothermia group were treated with the corresponding therapeutic methods. 72 h later, observed neurologic injury score, evaluated infarction area ratio by 2,3,5-tripheyl tetrazolium chloride (TTC) staining, determined apoptosis by TUNEL assay, and measured the phosphorylated Raf-1, MEK-2 and ERK1/2 protein expression levels in rat ischemic hippocampal tissues by Western blot assay.

Results

Compared with the blank control group and the sham operation group, after modeling, the neurologic injury score, infarction area ratio and apoptotic cells were increased, and phosphorylated Raf-1, MEK-2 and ERK1/2 protein expression levels were significantly increased in the model group; the differences were statistically significant (P<0.05 or P<0.01). Compared with the model group, after acupuncture or mild hypothermia therapy, neurologic injury score and infarction area ratio were decreased; apoptotic cells and phosphorylated Raf-1, MEK-2 and ERK1/2 protein expression levels were significantly decreased; the differences were statistically significant (P<0.05 or P<0.01). Compared with the acupuncture group, neurologic injury score and phosphorylated Raf-1, MEK-2 and ERK1/2 protein expression levels were decreased in the acupuncture plus mild hypothermia group; differences between the groups were statistically significant (P<0.05 or P<0.01). Compared with the mild hypothermia group, phosphorylated Raf-1, MEK-2 and ERK1/2 protein expression levels decreased in the acupuncture plus mild hypothermia group, and differences were statistically significant (P<0.01).

Conclusion

Acupuncture or mild hypothermia therapy can improve neurologic injury, reduce infarction area and apoptosis, which brought about protective effect on the brain tissues, in the MCAO model. The protective effect of acupuncture plus mild hypothermia group is the strongest. The mechanism may involve the MAPK/ERK pathway, by reducing the phosphorylated Raf-1, MEK-2 and ERK1/2 protein expression levels.
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2.

Objective

To explore the clinical efficacy of scalp acupuncture plus speech rehabilitation in treating Broca’s aphasia after cerebral stroke, for providing novel evidences for the treatment.

Methods

Ninety-one eligible patients with Broca’s aphasia after cerebral stroke were randomized into an observation group and a control group. Forty-six cases in the observation group were intervened by scalp acupuncture plus speech rehabilitation, while 45 cases in the control group were treated by speech rehabilitation alone. The aphasia battery of Chinese (ABC) and Boston diagnostic aphasia examination (BDAE) were adopted to evaluate the clinical efficacy.

Results

After the treatment, the scores of oral expression, reading and writing and global score in the observation group were significantly higher than those in the control group (all P<0.05). There was a significant difference in comparing the BDAE grading between the two groups after the treatment (P<0.05). After intervention, the basically-recovered plus markedly-effective rate was 45.7% in the observation group versus 24.4% in the control group, and the between-group difference was statistically significant (P<0.05).

Conclusion

Scalp acupuncture plus speech rehabilitation is effective in treating Broca’s aphasia after cerebral stroke, and worth promoting.
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3.

Objective

To investigate the effect of electroacupuncture (EA) at Ganshu (BL 18) and Shenshu (BL 23) on vascular endothelial growth factor (VEGF) and platelet endothelial cell adhesion molecule-1 (PECAM-1)/CD31 around the cerebral infarction focus in middle cerebral artery occlusion (MCAO) rats and the possible mechanism, thus to provide a new strategy for the treatment of cerebral ischemic stroke by acupuncture.

Methods

A total of 180 healthy male Sprague-Dawley (SD) rats were randomly divided into a sham operation group, a model group, an acupoint group and a non-acupoint group, 45 rats in each group. MCAO model was established using the modified line-embolus method in all rats except for those in the sham operation group; rats in the acupoint group were treated with EA at Ganshu (BL 18) and Shenshu (BL 23); rats in the non-acupoint group were treated with EA at the control points; rats in other 2 groups were only subjected to bundling without treatment. Ten rats in each group were randomly selected on the 3rd day, the 14th day and the 21st day after acupuncture stimulation to test the neurological function impairment. The expression levels of CD31 and VEGF were also detected.

Results

Compared with the model group and non-acupoint group, the neurological function score of the acupoint group was decreased at each time point, and the differences were statistically significant (P<0.05, P<0.01). The expressions of VEGF and CD31 in each group were the lowest on the 3rd day, reached the peak on the 14th day and still remained at high level on the 21st day. And the differences among groups were statistically significant both on the 14th day and the 21st day (P<0.05, P<0.01). Compared with the model group and the non-acupoint group, the expressions of VEGF and CD31 in the acupoint group were increased, and the differences were statistically significant (all P<0.05).

Conclusion

EA at Ganshu (BL 18) and Shenshu (BL 23) can significantly improve the neurological function score of MCAO model rats, and shows protective effect on cerebral ischemia. The protective mechanism may be related to the up-regulation of CD31 and VEGF expression around the cerebral infarction focus in the MCAO model rats and induction of angiogenesis.
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4.

Objective

To investigate the effects of acupuncture on the number of associated phosphorylated proteins in brain tissues of middle cerebral artery occlusion (MCAO) rats, based on the protein microarray technique.

Methods

The MCAO model was prepared according to the modified occlusion method using occlusion lines. Forty healthy Sprague-Dawley (SD) rats were randomly divided into 4 groups using the lottery method: a sham operation group, a model group, a control point group and an acupoint group, with 10 rats in each group. Rats in the sham operation group and the model group only received binding without acupuncture. Rats in the acupoint group received acupuncture at Dazhui (GV 14), Baihui (GV 20) and Shuigou (GV 25); rats in the control point group received acupuncture at non-acupoint control points. The needle was twisted once for 1 min after insertion and another time in the middle of the 30 min needle retaining. Acupuncture was conducted once every 12 h for 6 consecutive times. At the end of the experiment, the neurological impairment score was collected, and cells of the ischemic brain tissues were extracted. The protein phosphorylation of the related signaling was detected using the 720 phosphorylated antibody microarray technique, and the differentially expressed proteins between groups were screened.

Results

The neurological impairment scores after 72 h of treatment: compared with the sham operation group, the scores of the model group, the control point group and the acupoint group were significantly increased (P<0.01); compared with the model group, the scores of the acupoint group and the control point group were significantly decreased (P<0.01, P<0.05); the score of the acupoint group was better than that of the control point group (P<0.05). The results of the protein microarray: compared with the sham operation group, 48 proteins showed up-regulated phosphorylation (≥1.5 times) in the model group and the down-regulated was 28; compared with the model group, 35 proteins showed up-regulated phosphorylation in the control point group, and the down-regulated was 24. There were 29 proteins showing up-regulated phosphorylation in the acupoint group and the down-regulated was 51. The numbers of proteins involved in the function and signal transduction pathways were also different.

Conclusion

Acupuncture at Dazhui (GV 14), Baihui (GV 20) and Shuigou (GV 25) can effectively repair brain injury. The ischemic injury of brain tissue may be caused by imbalance of a variety of proteins, and acupuncture can promote brain tissue repair by multi-functional and multi-channel regulation of the protein disorders.
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5.

Objective

To observe the effect of electroacupuncture (EA) on the expression of erythropoie-tin-producing hepatocyte receptor B2 (EphB2) in the cortex around the infracted area of middle cerebral artery occlusion (MCAO) rats at different timing, and to reveal the possible mechanism of acupuncture in the treatment of cerebral ischemia.

Methods

A total of 180 male Sprague-Dawley (SD) rats were randomly divided into a sham operation group, a model group, an acupoint group and a non-acupoint group, with 45 rats in each group. Rats in each group were further divided into three subgroups: postoperative 3 d, postoperative 14 d and postoperative 21 d groups, with 15 rats in each subgroup. The MCAO model was made by the modified occlusion method. The neurological function score, 2,3,5-triphenyl tetrazolium chloride (TTC) staining, immunohistochemistry assay, immunofluorescence double labeling method and Western blot were used to detect the corresponding indicators.

Results

The neurological impairment of rats was most obvious at postoperative 3 d, and then gradually improved with time, which was more significant in the acupoint group (P<0.05). The change of infarcted volume was consistent with the neurological function impairment. The number of EphB2 positive cells (EphB2+) around the infarcted area was decreased significantly at postoperative 3 d, and then gradually improved with time, which returned to the same level as that in the sham operation group at postoperative 21 d. The increase was most significant in the acupoint group (P<0.05), and the positive cell number was higher than that in the sham operation group (P<0.01). Western blot and immunohistochemistry results were basically consistent. Immunofluorescence displayed that EphB2+ and postsynaptic density-95 positive (PSD-95+) were co-expressed, after the MCAO operation, in the cortical neuron around the infracted area, and the number of co-expressing cells was increased gradually with time, which was most significant in the acupoint group (P<0.05).

Conclusion

Electroacupuncture at Ganshu (BL 18) and Shenshu (BL 23) can significantly improve the neurological function and cerebral infarcted volume ratio of MCAO rats, which may be related to the activation of EphB2 expression in cortex around the infracted area and the promotion of synaptic remodeling.
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6.

Objective

To observe the clinical efficacy of acupuncture plus turtle-shell-partitioned moxibustion in treating diarrheapredominant irritable bowel syndrome (IBS-D).

Methods

Seventy-six patients were randomized into two groups: 39 cases in the observation group were intervened by acupuncture plus turtle-shell-partitioned moxibustion, while 37 cases in the control group by the same acupuncture treatment, once a day, 10 d as a treatment course, for 2 courses in total. The improvements of symptoms were observed at the end of the intervention in both groups.

Results

The total effective rate was 89.7% in the observation group versus 67.6% in the control group, and the difference was statistically significant (P<0.05).

Conclusion

Acupuncture plus turtle-shell-partitioned moxibustion can significantly improve the symptoms of IBS-D, and can produce a more significant efficacy than acupuncture alone.
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7.

Objective

To evaluate the clinical efficacy of acupuncture plus tuina in treating cervical vertigo (CV).

Methods

One hundred CV patients were randomized into an observation group and an acupuncture group by the random number table, with 50 cases in each group. The acupuncture group received acupuncture at Xiang Ba Zhen (eight acupoints on the nape); the observation group received tuina treatment in addition to the Xiang Ba Zhen acupuncture. The two groups were both treated once every other day for 10 sessions in total. The two groups were examined by transcranial cerebral Doppler (TCD) before and after the treatment, and their therapeutic efficacies were evaluated.

Results

After the treatment, the mean velocity (Vm) of vertebral artery (VA) and basilar artery (BA) showed significant improvement in both groups (all P<0.001); there were significant differences in the Vm of VA and BA between the two groups (both P<0.05). The total effective rate was 100.0% in the observation group versus 82.0% in the acupuncture group, and the difference was statistically significant (P<0.01).

Conclusion

Xiang Ba Zhen acupuncture as a monotherapy or used together with tuina can improve CV, but Xiang Ba Zhen plus tuina can produce a more significant efficacy.
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8.

Objective

To observe the clinical effect of acupuncture plus occupation therapy for fine motor functions in children with spastic cerebral palsy.

Methods

A total of 80 cerebral palsy kids with fine motor dysfunction were allocated into two groups by envelop, 40 cases in each group. Cases in the control group were treated with occupation therapy. Based on the therapy given to the control group, cases in the treatment group were supplemented with acupuncture at the points of the three yang meridians of hand. The treatment was done every other day and 10 times for a course. There was a 15-day interval between two courses, and 3 courses in total. The therapeutic efficacies were evaluated using Peabody developmental motor scale 2 (PDMS-2) and modified Ashworth scale (MAS) before and after treatment.

Results

After treatment, the standard score for grasping (Grs), standard score for visual-motor integration (Vis), fine motor quotient (FMQ) and modified Ashworth scale (MAS) were significantly improved in both groups (P<0.05). The improvement in the treatment group was more obvious than that in the control group (P<0.01).

Conclusion

Acupuncture plus occupation therapy can achieve better effect than occupation therapy alone in improving fine motor functions of upper limbs in cerebral palsy kids.
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9.

Objective

To observe and compare the therapeutic efficacies of heat-sensitive moxibustion plus Western medication, dry Western medication, and acupuncture plus TDP in treating peripheral facial palsy (FP).

Methods

Ninety FP patients were randomized into a Western medication group, a heat-sensitive moxibustion group, and an acupuncture group by using sealed envelope, 30 cases in each group. The Western medication group was intervened by conventional Western medication; the heat-sensitive moxibustion group was by heat-sensitive moxibustion in addition to the same Western medication; the acupuncture group was by the Western medication plus acupuncture and TDP radiation. For the three groups, 6-day treatment was taken as a treatment course, with a 2-day interval between 2 courses, and totally 4 treatment courses were observed.

Results

After intervention, the modified Portmann scores were changed significantly in the three groups (P<0.05), and the improvements in the heat-sensitive moxibustion group and the acupuncture group were both superior to that in the Western medication group. The recovery plus markedly effective rate of the acupuncture group was significantly different from that of the Western medication group (P<0.05), and there was a significant difference in comparing the recovery plus markedly effective rate between the heat-sensitive moxibustion group and acupuncture group (P<0.05).

Conclusion

Heat-sensitive moxibustion is effective in treatment peripheral facial paralysis, and this method is free of pain, causing no adverse reactions, and worth promotion in clinic.
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10.

Objective

To observe the clinical efficacy of buccal acupuncture plus exercise therapy in treating scapulohumeral periarthritis (SP).

Methods

Sixty-three SP patients were intervened by buccal acupuncture plus exercise therapy. The treatment was given once every day, 5 sessions as a course, with a 2-3 d interval between two courses. The therapeutic efficacy was observed after 3 courses of treatment.

Results

Thirty-five patients were recovered, 23 cases were improved, while 5 cases showed ineffective, and the total effective rate was 92.1%.

Conclusion

Buccal acupuncture plus exercise therapy can produce a significant efficacy in treating SP, and thus is worth promotion in clinic.
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11.

Objective

To observe the therapeutic efficacy of acupuncture plus Tai Ji Quan (Tai Chi) in recovering the neurological function and treating depression state in post-stroke depression patients, together with a 12-month follow-up.

Methods

A total of 105 eligible post-stroke depression patients were randomized into an acupuncture plus Tai Ji group (53 cases) and a control group (52 cases) based on their visiting sequence. The patients all received routine treatment and rehabilitation training for stroke. In addition, the control group was given oral administration of citalopram hydrobromide tablets, 1 month as a course of treatment, for 3 courses in total. Meanwhile, the acupuncture plus Tai Ji group received acupuncture and practiced Tai Ji Quan, for 1 month and 12 months respectively. Before the intervention, after 1-month intervention and 12 months later, the National Institute of Health stroke scale (NIHSS), Barthel index (BI) and Hamilton depression rating scale (HAMD) were adopted for efficacy evaluation.

Results

Prior to the intervention, there were no significant differences in HAMD, NIHSS and BI scores between the two groups (all P>0.05); after 1-month intervention, there were significant between-group differences in NIHSS, BI and HAMD scores (P<0.05 or P<0.01); the 12-month follow-up revealed significant between-group differences in NIHSS, BI and HAMD scores (all P<0.01). In the treatment of stroke, the total effective rate was 84.4% in the acupuncture plus Tai Ji group, significantly higher than 68.9% in the control group (P<0.05); in the treatment of depression, the total effective rate was 86.7% in the acupuncture plus Tai Ji group, significantly higher than 77.8% in the control group (P<0.05).

Conclusion

Acupuncture plus Tai Ji Quan can produce a significant efficacy in improving the limb motor function and depression in post-stroke depression patients.
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12.

Objective

To observe the clinical effects of tuina manipulations plus the functional training on scapulohumeral periarthritis (SP), and provide the better therapeutic plan for SP patients.

Methods

A total of 76 cases with SP in conformity with the inclusion criteria were randomly divided into a tuina group and an acupuncture group, 38 patients in each group. All the patients were instructed to do functional training under the guidance of the professional medical practitioners. The patients in the tuina group were treated additionally with tuina manipulations, while the patients in the acupuncture group were added with acupuncture treatment. The two groups were treated once every day. After ten sessions, the changes in the scores of visual analog scale (VAS) and Melle were observed, and the clinical effect was compared.

Results

After the treatment, VAS and Melle scores were all lower in the tuina group than those in the acupuncture group, with statistical significances between the two groups (P<0.05). The remarkable effective rate was 5.3% in the acupuncture group and 21.1% in the tuina group. The remarkable effective rate was higher in the tuina group than that in the acupuncture group, with a statistical significance (P<0.05).

Conclusion

Tuina manipulations plus functional training for SP can effectively alleviate pain and restore the functions of the shoulder joint, with a better effect than acupuncture plus functional training.
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13.

Objective

To evaluate the effectiveness of abdominal acupuncture plus the Confluent Points of the Eight Extraordinary Meridian in treating chronic pharyngitis.

Methods

Thirty eligible subjects with chronic pharyngitis were given abdominal acupuncture plus needling Lieque (LU 7) and Zhaohai (KI 6), two out of the Confluent Points of the Eight Extraordinary Meridian, once a day, 10 sessions as a course, and the therapeutic efficacy was evaluated after a treatment course.

Results

After a treatment course, of the 30 subjects, 21 were recovered, 5 showed markedly effective, 2 were improved, and 2 failed, the total effective rate was 93.3%.

Conclusion

Abdominal acupuncture plus the Confluent Points of the Eight Extraordinary Meridian is effective in treating chronic pharyngitis, worth promoting in clinic.
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14.

Objective

To observe the effect of acupuncture, tuina plus rehabilitative therapy on lower limb motor dysfunction in infants with spastic cerebral palsy.

Methods

A total of 60 infants with spastic cerebral palsy were randomly divided into a treatment group and a control group by random digital table, 30 cases in each group. The treatment group was treated with acupuncture, tuina therapy plus rehabilitative therapy of Western medicine. The control group was simply treated with rehabilitative therapy of Western medicine, as same as that for the treatment group. The assessment was respectively given to the sick infants before the treatment and after the treatment of six months, to evaluate lying and rolling scores in dimension A, to evaluate sitting score in dimension B, to evaluate crawling and kneeling scores in dimension C, and evaluate standing score in dimension D in the gross motor functions and determine the muscle tone of the gastrocnemius muscle by modified Ashworth scale (MAS).

Results

The differences were not statistically significant in comparison of the gross motor functions and the muscle tone of the gastrocnemius muscle between the two groups of sick infants before the treatment (P>0.05); after the treatment of six months, the above items were obviously improved in the two groups (P<0.01), better in the treatment group than in the control group, with the statistical significance in the differences between the groups (P<0.01).

Conclusion

Acupuncture, tuina plus rehabilitative therapy of Western medicine are remarkable in the therapeutic effects in the treatment of motor disorders of the lower limbs in the sick infants with spastic cerebral palsy. This therapeutic method is safe, simple and convenient and needs to be clinically popularized and applied.
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15.

Objective

To observe the clinical efficacy of warm needling moxibustion plus tuina in treating knee osteoarthritis (KOA) due to cold-dampness blocking collaterals.

Methods

Forty-eight KOA patients were randomized into 2 groups by their visiting sequence, 24 cases in each group. The treatment group was intervened by warm needling moxibustion plus tuina, while the control group was treated with acupuncture plus tuina. The two groups were both treated once a day, 30 min for each session, 10 d as a treatment course, totally for 3 treatment courses. The visual analogue scale (VAS) and Lysholm knee scoring scale (LKSS) were observed before and after the treatment to evaluate the clinical efficacy.

Results

After 3 treatment courses, the VAS and LKSS scores were significantly changed in the two groups (P<0.01), and the between-group differences were also statistically significant (P<0.01). The markedly-effective rate was 83.3% in the treatment group versus 66.7% in the control group, and the difference was statistically significant (P<0.05).

Conclusion

Warm needling moxibustion plus tuina can produce a more significant efficacy than acupuncture plus tuina in treating KOA due to cold-dampness blocking collaterals.
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16.

Objective

To observe the clinical efficacy of acupuncture plus moxibustion at Ciliao (BL 32) for primary dysmenorrhea (PD) due to cold-dampness.

Methods

A total of 58 cases with PD due to cold-dampness were randomly allocated into an observation group (n=29) and a control group (n=29). Patients in the observation group were treated with acupuncture and suspended moxibustion at Ciliao (BL 32), whereas patients in the control group were treated with routine acupuncture alone. After three courses of treatment, the clinical efficacy was evaluated and compared between the two groups.

Results

After treatment, the symptom scores were significantly reduced in both groups (P<0.05), but there were no significant between-group differences in clinical efficacy and symptom scores (P>0.05).

Conclusion

With fewer points and less pain, acupuncture-moxibustion at Ciliao (BL 32) can obtain similar effect as routine acupuncture therapy for PD due to cold-dampness.
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17.

Objective

To investigate the clinical efficacy of combining auricular and routine acupuncture for peripheral facial paralysis in acute stage.

Methods

A total of 60 eligible cases were randomly allocated into a treatment group (n=30) and a control group (n=30). Cases in treatment group received auricular and routine acupuncture, whereas cases in the control group received routine acupuncture alone. Both groups were treated for 10 d.

Results

The recovery rate was 73.3% in the treatment group and 53.3% in the control group, showing a statistical difference (P<0.05).

Conclusion

Combining auricular and routine acupuncture is effective for peripheral facial paralysis in acute stage and has a better effect than routine acupuncture.
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18.

Objective

To observe the effect of acupuncture in regulating ubiquitin-proteasome pathway (UPP), and discuss the action of acupuncture in intervening heroin-induced brain damage.

Methods

Thirty male Sprague-Dawley (SD) rats were divided into a control group, a model group and an acupuncture group by using the random number table. Rats in the model and acupuncture groups received intramuscular heroin injection for successive 8 d at a progressively increased dose. Afterwards, the injection was suspended for 5 d for withdrawal. The heroin relapse rat model was established by repeating the drug addiction and withdrawal process for 3 times. The control group followed the step of the model establishment, but was given intramuscular injection of normal saline at the stage of addiction and no intervention at the stage of withdrawal; the model group was given intramuscular heroin injection at a progressively increased dose at the addiction stage and no intervention at the withdrawal stage; the acupuncture group was dealt in the same way as the model group at the addiction stage, but received acupuncture at Baihui (GV 20) and Dazhui (GV 14) at the withdrawal stage, with the needles retained for 30 min each time, 1 session a day, for successive 5 d. On the 39th day, brain tissues were extracted from the hippocampus and ventral tegmental area (VTA) of the three groups of rats. The apoptosis of brain nerve cells was detected by using terminal deoxynucleotidyl transferase-mediated nick and labeling (TUNEL). The mRNA and protein expressions of ubiquitin (Ub), ubiquitin protein ligase (E3) and 26S were examined by immunohistochemistry and quantitative real-time polymerase chain reaction (RT-qPCR).

Results

Compared with the model group, rat’s hippocampus and VTA in the acupuncture group showed significantly fewer cells positively stained by TUNEL staining (P<0.01), and its mRNA and protein expressions of Ub, E3, 26S were significantly lower (P<0.01).

Conclusion

Reducing nerve cell apoptosis and regulating the mRNA and protein expressions of Ub, E3 and 26S in rat’s hippocampus and VTA are possibly one of the action mechanisms of acupuncture in intervening heroin-induced brain damage.
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19.

Objective

To categorize and summarize the clinical and mechanism studies of the past 30 years on the treatment of Hashimoto’s thyroiditis (HT) with moxibustion, moxibustion plus medication, and acupuncture plus medication, etc., and to analyze the current problems.

Methods

The clinical and laboratory studies related to the treatment of HT with acupuncture-moxibustion therapies published before June 2015 were retrieved from MEDLINE, Excerpta Medica Database (EMBASE), China National Knowledge Infrastructure (CNKI), Wanfang Academic Journal Full-text Database (Wanfang) and Chongqing VIP Database (CQVIP).

Results

Moxibustion, moxibustion plus medication, and acupuncture plus medication can produce certain therapeutic effects in treating HT.

Conclusion

The research on the treatment of HT with acupuncture-moxibustion therapies is rather limited in the amount and content. In the future, standardization should be fortified, specific moxibustion research needs deepening, and the action mechanism of moxibustion should be emphasized.
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20.

Objective

To observe the clinical efficacy of acupuncture plus umbilicus application with Chinese medicine for detrusor underactivity.

Methods

A total of 46 male patients with detrusor underactivity who were admitted to our hospital between January and December 2017 were randomized into a control group and an observation group, with 23 cases in each group. The control group received intermittent catheterization and routine nursing, and the observation group was treated with acupuncture plus umbilicus application with Chinese medicine on the basis of the treatment of the control group. The comprehensive efficacy, the improvement of bladder urine residue and maximum flow rate of the two groups were observed.

Results

No cases dropped out in the two groups. After the intervention, the total effective rate of the observation group was 78.3%, which was significantly higher than 52.2% of the control group (P<0.05). After intervention, the improvements of bladder urine residue and maximum flow rate in the observation group were statistically different from those in the control group (both P<0.05).

Conclusion

The combination of acupuncture and umbilicus application with Chinese medicine added on the basis of intermittent catheterization and routine nursing has a certain effect in treating male patients with detrusor underactivity, and is worth further clinical study.
  相似文献   

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