虚寒型慢性腹泻患者指针疗法配合肠道水疗的效果观察

目的探讨指针疗法配合肠道水疗治疗虚寒型慢性腹泻患者效果。方法将160例虚寒型慢性腹泻患者随机分成对照组及观察组各80例,对照组进行肠道水疗后予以中药灌肠治疗;观察组在此基础上,予长强穴及大肠俞穴局部指针治疗。观察并记录两组患者不良反应发生率、疗程和治疗效果。结果观察组治疗效果显著优于对照组（P〈0．05）,疗程及不良反应显著短于、少于对照组（P〈0．01,P〈0．05）。结论指针疗法配合肠道水疗能提高虚寒型慢性腹泻患者的疗效,缩短疗程,减少治疗过程中的不良反应,提高患者治疗依从性。     

结肠水疗在结肠镜检查患者肠道准备中的应用

目的 探讨结肠水疗在结肠镜检查患者肠道准备中的应用效果.方法 选择行电子结肠镜检查患者200例,观察组(门诊患者)124例,使用结肠水疗仪配合口服硫酸镁清洁肠道;对照组(住院患者)76例,单纯口服硫酸镁进行肠道准备.结果 观察组肠道清洁效果、到达回盲瓣成功率及患者对肠道准备的耐受程度显著优于对照组(均P<0.05).结论 使用结肠水疗仪配合口服硫酸镬进行肠道准备成功率高,患者痛苦小,易耐受.     

结肠水疗在结肠镜检查患者肠道准备中的应用

目的探讨结肠水疗在结肠镜检查患者肠道准备中的应用效果。方法选择行电子结肠镜检查患者200例,观察组（门诊患者）124例,使用结肠水疗仪配合口服硫酸镁清洁肠道;对照组（住院患者）76例,单纯口服硫酸镁进行肠道准备。结果观察组肠道清洁效果、到达回盲瓣成功率及患者对肠道准备的耐受程度显著优于对照组（均P〈0．05）。结论使用结肠水疗仪配合口服硫酸镁进行肠道准备成功率高,患者痛苦小,易耐受。     

慢性腹泻患者的辨证施护

目的 探讨慢性腹泻患者辨证施护的方法及效果。方法 将50例慢性腹泻患者随机分为对照组（24例）和干预组（26例），两组均给予抗炎止泻治疗，对照组按照常规护理，干预组予以辨证施护。结果 干预组治疗总有效率92．3％，对照组62．5％．两组比较．差异有显著性意义（P〈0．05）。结论 辨证施护可提高慢性腹泻患者疗效。     

结肠水疗与莫沙必利治疗慢性功能性便秘的临床对照观察

目的:观察结肠水疗对慢性功能性便秘(CFC)的治疗效果。方法:将CFC患者203例随机分A组66例,行结肠水疗;B组69例,行结肠水疗及服用枸橼酸莫沙必利治疗;C组68例,服用枸橼酸莫沙必利治疗。2周后观察疗效。结果:A,B,C 3组有效率分别为:78.79%(52/66)、86.96%(60/69)、72.06%(49/68)。经统计学处理B,C两组疗效有明显差异(P<0.05),观察有显效及有效者3、6个月,A组分别有14(26.92%)、18例(34.62%)复发;B组分别有17(28.33%)、20例(33.33%)复发,C组分别有31(63.27%)、39例(79.59%)复发。A,B结肠水疗组复发率明显低于枸橼酸莫沙必利治疗组(P<0.05)。结论:结肠水疗治疗慢性功能性便秘效果好,治愈后复发率低。     

醒脾养儿颗粒治疗脾胃虚弱型小儿慢性腹泻的疗效观察

目的:观察醒脾养儿颗粒治疗脾胃虚弱型小儿慢性腹泻的疗效.方法:将脾胃虚弱型慢性腹泻患儿86例随机分为对照组和观察组,每组43例.对照组患儿采用常规对症治疗以及营养支持,在此基础上,观察组患儿加用醒脾养儿颗粒进行治疗,观察2组患儿的疗效、各项临床症状改善情况以及治疗前后血清免疫球蛋白的水平变化情况.结果:观察组患儿治疗总...     

慢性腹泻的自我调理

慢性腹泻病因繁多,病程缠绵,积极寻找和消除病因是治疗的关键,日常自我调理亦十分重要,不可忽视。慢性腹泻患者的自我护理大致有以下几方面：     

大肠水疗结合辨证保留灌肠治疗慢性功能性便秘临床疗效观察

为探讨大肠水疗结合辨证保留灌肠治疗慢性功能性便秘的治疗效果,回顾162例慢性功能性便秘患者资料,其中86例采用大肠水疗结合辨证保留灌肠治疗（治疗组）,76例采用常规中药汤剂口服治疗（对照组）,对比分析两组患者临床疗效。结果显示,治疗组显效46例,有效28例,无效12例,总有效率86．0％;对照组显效36例,有效24例,无效16例,总有效率78．9％;治疗组总有效率高于对照组,P〈o．05。观察显效及有效者6个月,治疗组74例患者中复发12例（16．2％）,对照组60例患者中复发18例（30．0％）,治疗组复发率明显低于对照组,P〈0．05。结果表明,大肠水疗结合辨证保留灌肠治疗慢性功能性便秘效果好,治愈后复发率低。     

药穴指针疗法治疗胃食管反流病的护理

目的探讨药穴指针疗法治疗胃食管反流病的护理方法。方法将120例胃食管反流患者随机分为观察组和对照组各60例。对照组药穴指针疗法后按胃食管反流病常规护理,观察组在此基础上配合中医特色护理,包括调摄精神、饮食调护、五音疗法、生活起居指导及循经皮肤护理等。结果观察组临床疗效显著优于对照组（P〈0.05）;两组患者满意度及平均住院时间比较,差异有统计学意义（P〈0.05,P〈0.01）。结论药穴指针疗法治疗胃食管反流病中采用中医特色护理,可强化疗效,缩短住院治疗有效时间,提高患者满意度。     

药穴指针疗法治疗胃食管反流病的护理

目的探讨药穴指针疗法治疗胃食管反流病的护理方法。方法将120例胃食管反流患者随机分为观察组和对照组各60例。对照组药穴指针疗法后按胃食管反流病常规护理,观察组在此基础上配合中医特色护理,包括调摄精神、饮食调护、五音疗法、生活起居指导及循经皮肤护理等。结果观察组临床疗效显著优于对照组(P0.05);两组患者满意度及平均住院时间比较,差异有统计学意义(P0.05,P0.01)。结论药穴指针疗法治疗胃食管反流病中采用中医特色护理,可强化疗效,缩短住院治疗有效时间,提高患者满意度。     

慢性腹泻患者的辨证施护

目的 探讨慢性腹泻患者辨证施护的方法及效果.方法 将50例慢性腹泻患者随机分为对照组(24例)和干预组(26例),两组均给予抗炎止泻治疗,对照组按照常规护理,干预组予以辨证施护.结果 干预组治疗总有效率92.3%,对照组62.5%,两组比较,差异有显著性意义(P＜0.05).结论 辨证施护可提高慢性腹泻患者疗效.     

Intestinal Transplantation for Chronic Intestinal Pseudo-Obstruction in Adult Patients

Intestinal transplantation (ITx) has become a life-saving procedure for patients with irreversible intestinal failure who can no longer be maintained on parenteral nutrition (PN). This report presents the results of our experience on ITx in patients suffering from chronic intestinal pseudo-obstruction (CIPO). Between December 30, 2000 and May 30, 2003 six adult patients affected by CIPO underwent primary ITx at our Center. Pre-transplant evaluation, indication for ITx and surgical technique are reported. On December 30 2003, the mean follow-up was 25.0 months. No peri-operative deaths occurred in the study population and five out of six patients are alive, with 1-year patient and graft survival of 83.3% and 66.6%. Although our series is limited by the number of patients, our experience suggests that ITx transplantation should be considered in adult patients suffering from CIPO and PN life-threatening complication.     

多种微创方法联合个体化治疗重症急性胰腺炎

目的 分析多种微创方法联合个体化治疗重症急性胰腺炎(severe acute pancreatitis,SAP)的价值.方法 总结我院1998年9月至2008年10月期间收治的67例SAP患者的临床资料,均采用多种微创方法联合个体化治疗的方案.检测患者治疗前、后APACHE Ⅱ评分、CT积分、WBC计数、总胆红素、AST、血糖、淀粉酶、脂肪酶、C反应蛋白、肿瘤坏死因子-α、血尿素氮、肌酐及氧合指数(PaO2/FiO2)的变化,并记录腹痛缓解时间、开腹手术率、死亡率、治愈率,住院时间、住院费用等.结果 本组患者经治疗后各项检测指标均较治疗前明显改善(P<0.001).腹痛缓解时间为(20.17±14.16) h,开腹手术率为6.0%(4/67),死亡率为7.5%(5/67),治愈率为92.5%(62/67),住院时间(30.85±28.37) d,住院费用(59 295.78±34 564.44)元.结论 针对SAP患者每例个体的不同病因、严重程度、病期及合并症采用多种微创方法联合个体化治疗,可明显改善各项检测指标,提高治愈率.     

Effect of Intervention Therapy Based on Liver-spleen Correlation Theory on Intestinal Mucosal Barrier Function in Patients with Chronic Severe Hepatitis

[目的]观察应用肝脾相关理论干预慢性重型肝炎的临床疗效及探讨其对肠黏膜屏障的保护作用.[方法]选取慢性重型肝炎患者60例,采用简单随机法将患者随机分为对照组(基础治疗+凉血解毒法)30例和观察组(基础治疗+凉血解毒法+健脾益气法)30例,疗程2周,共2个疗程,观察治疗前后症状积分、血清学变化和治疗后总有效率,同时观察2组患者的肠黏膜通透性(血清二胺氧化酶水平、尿中乳果糖/甘露醇排出率)和血浆内毒素水平.[结果]观察组的总有效率(80.0％)优于对照组(66.7％),差异有显著性意义(P＜0.05).2组均可改善临床症状,改善肝功能,升高凝血酶原活动度,且观察组作用优于对照组,差异有显著性意义(P＜0.05);2组治疗前内毒素水平、尿中乳果糖/甘露醇排出率比较,差异均无显著性意义(P＞0.05),治疗后观察组血浆内毒素水平、尿中乳果糖/甘露醇排出率较治疗前显著降低(P＜0.05),且与对照组比较差异有显著性意义(P＜0.05).[结论]应用肝脾相关理论治疗慢性重型肝炎可提高临床疗效,并可改善慢性重型肝炎患者肠黏膜屏障功能,纠正肠源性内毒素血症.     

Therapeutics for Childhood Neurofibromatosis Type 1 and Type 2

Neurofibromatosis type 1 (NF1) and type 2 (NF2) are genetically and medically distinct neurocutaneous disorders that are both associated with tumors affecting the central and peripheral nervous systems. NF1 has a frequency of 1 in 3,000, compared with 1 in 30,000 for NF2. Careful surveillance is important for both conditions, to allow early identification and treatment of complications. The most common and important problems in NF1 are cognitive impairment, optic pathway gliomas, plexiform neurofibromas, and orthopaedic issues. Early intervention and tailored educational programs are indicated for learning difficulties. Attention deficit hyperactivity disorder may be amenable to treatment with stimulant medication. A clinical trial is under way to evaluate lovastatin in the treatment of cognitive problems in children with NF1. Chemotherapy with vincristine and carboplatin is the current standard of care for symptomatic optic pathway gliomas, but new agents with improved efficacy are needed. Plexiform neurofibromas may be treated with surgery, but often recur. To date, no medical therapy has proven effective in limiting plexiform neurofibroma growth, but several candidate medications are under consideration in clinical trials. Malignant peripheral nerve sheath tumors may arise in preexisting plexiform neurofibromas, so changes in tumor growth or an increase in pain or focal neurologic deficit should prompt further investigation and early treatment with wide surgical resection, with or without adjuvant chemotherapy or radiotherapy. Specialist surgical intervention may be needed for scoliosis and tibial pseudoarthrosis. In NF2, surgical treatment remains a cornerstone of management for symptomatic progressive vestibular schwannomas, meningiomas, and spinal tumors. Vascular endothelial growth factor inhibitors show promise for the treatment of vestibular schwannomas, with the aim of delaying surgery, and other targeted molecular therapies are becoming available as investigational options. Hearing aids and brainstem and cochlear implants have a role in optimizing functional hearing in some patients. Specialist ophthalmology input should be arranged to monitor for ophthalmologic complications. A coordinated effort is needed to enroll NF1 and NF2 patients in international multicenter clinical trials of promising new pharmacologic agents. Genetic testing is useful for prenatal diagnosis and may be important in understanding individual responses to novel medical therapies in the future. Effective transition to adult services is important, considering the likelihood of further complications in the adult years.     

Benefit of Sustained Virological Response to Combination Therapy on Graft Survival of Liver Transplanted Patients with Recurrent Chronic Hepatitis C

Recurrent hepatitis C infection is an important cause of progressive fibrosis, cirrhosis and graft loss after liver transplantation. Treatment for post-transplant recurrence results in sustained virological response (SVR) in up to 30% of cases. The aim of this study was to evaluate the impact of SVR on patients and graft survival. Thirty-four patients with an SVR to IFN-ribavirin were included. Forty-six nonresponders to the combination formed the control group. Follow-up data were recorded every 6 months and included HCV RNA, and the occurrence of clinical problems (cirrhosis, decompensation, hepatocellular carcinoma, death). A graft biopsy was performed every year. The mean follow-up duration was 52 months in responders and 57 months in nonresponders. Two patients died in each group of patients. Two patients with SVR developed late virological relapse. Fibrosis decreased in 38% of patients with SVR, remained stable in 44% and worsened in 18%. In contrast, fibrosis increased in the majority of nonresponder patients (74%, p<0.001). At the end of follow-up, no patient without cirrhosis at inclusion developed cirrhosis of the graft versus 9 among nonresponder patients (p=0.009). No difference in patient survival was observed in the two groups. In conclusion, this study shows that HCV eradication has a positive impact on graft survival.     

老年2型糖尿病患者运动疗法中的护理干预

目的 探讨老年2型糖尿病患者在运动疗法中实施护理干预的效果.方法 将70例老年2型糖尿病患者随机分为干预组和对照组各35例.两组均给予饮食、心理疗法及药物治疗.对照组自行锻炼,干预组对运动疗法中的运动方式、强度、时间、时机等进行护理干预.结果 干预1个月后,干预组空腹血糖、餐后2 h血糖、糖化血红蛋白值显著低于对照组(均P＜0.05);同时干预组血压改善明显(均P＜0.05),血糖水平控制总有效率达80.00%(均P＜0.05).结论 对老年2型糖尿病患者的运动疗法实施护理干预,可使运动安全有效,不但减少了降糖药物的用量,缩短疗程,延缓了并发症的发生和发展,而且提高了患者的生活质量.     

Vancomycin Therapy for Serious Staphylococcal Infections in Chronic Hemodialysis Patients

Vancomycin therapy during 7 episodes of serious staphylococcal infections in chronic hemodialysis patients was monitored by a sensitive bioassay technique. One gm of vancomycin was given during dialysis at a mean dosage interval of 7 days for a mean duration of 48 days. Serum peak and trough vancomycin levels were monitored during therapy. Accumulation of vancomycin occurred in 1 patient on prolonged therapy; progressive rising trough levels required a reduction in vancomycin dosage. Pre and post-dialysis vancomycin levels in one patient were unchanged. Vancomycin was effective in erradication of all staphylococcal infections and bacteremias. Three A-V shunt infections required surgical revision; 2 A-V fistula infections were salvaged with vancomycin therapy alone. We conclude that 1 gm vancomycin every 7 days is an effective regimen for serious staphylococcal infections in chronic hemodialysis patients. Monitoring of vancomycin levels insures maintenance of adequate levels and prevents toxic accumulation.