共查询到20条相似文献,搜索用时 31 毫秒
1.
C.L. Goulart F.R. Caruso G.P.T. Arêas P.B. dos Santos P.F. Camargo L.C.S. de Carvalho M.G. Roscani R.G. Mendes A. Borghi-Silva 《Brazilian journal of medical and biological research》2021,54(2)
The objective of this study was to investigate the impact of chronic obstructive pulmonary disease (COPD)-heart failure (HF) coexistence on linear and nonlinear dynamics of heart rate variability (HRV). Forty-one patients (14 with COPD-HF and 27 HF) were enrolled and underwent pulmonary function and echocardiography evaluation to confirm the clinical diagnosis. Heart rate (HR) and R-R intervals (iRR) were collected during active postural maneuver (APM) [supine (10 min) to orthostasis (10 min)], respiratory sinus arrhythmia maneuver (RSA-M) (4 min), and analysis of frequency domain, time domain, and nonlinear HRV. We found expected autonomic response during orthostatic changes with reduction of mean iRR, root mean square of successive differences between heart beats (RMSSD), RR tri index, and high-frequency [HF (nu)] and an increased mean HR, low-frequency [LF (nu)], and LF/HF (nu) compared with supine only in HF patients (P<0.05). Patients with COPD-HF coexistence did not respond to postural change. In addition, in the orthostatic position, higher HF nu and lower LF nu and LF/HF (nu) were observed in COPD-HF compared with HF patients. HF patients showed an opposite response during RSA-M, with increased sympathetic modulation (LF nu) and reduced parasympathetic modulation (HF nu) (P<0.05) compared with COPD-HF patients. COPD-HF directly influenced cardiac autonomic modulation during active postural change and controlled breathing, demonstrating an autonomic imbalance during sympathetic and parasympathetic maneuvers compared with isolated HF. 相似文献
2.
Bartels MN Jelic S Ngai P Gates G Newandee D Reisman SS Basner RC De Meersman RE 《Respiratory physiology & neurobiology》2004,144(1):91-98
Heart rate variability (HRV) and systolic blood pressure variability (BPV) during incremental exercise at 50, 75, and 100% of previously determined ventilatory threshold (VT) were compared to that of resting controlled breathing (CB) in 12 healthy subjects. CB was matched with exercise-associated respiratory rate, tidal volume, and end-tidal CO(2) for all stages of exercise. Power in the low frequency (LF, 0.04-0.15 Hz) and high frequency (HF, >0.15-0.4 Hz) for HRV and BPV were calculated, using time-frequency domain analysis, from beat-to-beat ECG and non-invasive radial artery blood pressure, respectively. During CB absolute and normalized power in the LF and HF of HRV and BPV were not significantly changed from baseline to maximal breathing. Conversely, during exercise HRV, LF and HF power significantly decreased from baseline to 100% VT while BPV, LF and HF power significantly increased for the same period. These findings suggest that the increases in ventilation associated with incremental exercise do not significantly affect spectral analysis of cardiovascular autonomic modulation in healthy subjects. 相似文献
3.
Autonomic nervous function and localization of cerebral activity during lavender aromatic immersion.
Xudong Duan Manabu Tashiro Di Wu Tomoyuki Yambe Qingtian Wang Takehisa Sasaki Kazuaki Kumagai Yun Luo Shin-ichi Nitta Masatoshi Itoh 《Technology and health care》2007,15(2):69-78
Changes in the autonomic nervous activity can be induced by various sensory and emotional stimuli. The authors examined whether the power spectral analysis of heart rate variability (HRV) could detect changes in autonomic tone following a lavender aroma treatment or not. Healthy young women (n=10, 23+/-3 years old) underwent continuous electrocardiographic (ECG) monitoring before and after (10, 20, 30 minutes) the lavender fragrance stimuli. HRV was expressed by three indices: low (0.04-0.15 Hz) and high (0.15-0.40 Hz) frequency components (nLF and nHF, respectively) as well as LF/HF ratio. Increases in the parasympathetic tone were observed after the lavender fragrance stimulus as seen as increases in the HF component and decreases in the LF/HF. Additional measurement with positron emission tomography (PET) demonstrated the regional metabolic activation in the orbitofrontal, posterior cingulate gyrus, brainstem, thalamus and cerebellum, as well as the reductions in the pre/post-central gyrus and frontal eye field. These results suggested that lavender aromatic treatment induced not only relaxation but also increased arousal level in these subjects. 相似文献
4.
To our knowledge, the relationship between all four endogenous female sex hormones and resting cardiac autonomic function has not been studied. The aim of the current study was to examine the association between the normal endogenous levels of oestrogen (17beta-oestradiol), progesterone, luteinising hormone and follicle-stimulating hormone and heart rate variability (HRV) during the menstrual cycle in young eumenorrheic women. Ten healthy, young, female subjects volunteered for this study. HRV and endogenous hormone levels were recorded at three phases of the menstrual cycle: menses (day 3.8 +/- 0.5), ovulation (day 15.8 +/- 0.7) and luteal (day 22.1 +/- 0.4) to ensure HRV recordings at times of low (menses) and high (ovulation and luteal) hormonal influence. Heart rate recordings were obtained from supine resting subjects and analysed on a Holter analysis system. Total power (TP, 0-1.0 Hz), low frequency (LF, 0.041-0.15 Hz), high frequency (HF, 0.15-0.80 Hz) and LF/HF components of HRV were examined. Despite a significantly greater HR at ovulation and normal cyclic variations in all endogenous sex hormone levels, no measure of HRV was significantly different between menstrual cycle phases. Significant correlations between oestrogen levels and absolute measures of HRV at ovulation were identified. The results of the current study demonstrated that the normal cyclic variations in endogenous sex hormone levels during the menstrual cycle were not significantly associated with changes in cardiac autonomic control as measured by HRV. Significant correlation between peak oestrogen levels and HRV measures at ovulation provided further support for the reported cardioprotective effects of oestrogen in healthy females. 相似文献
5.
Influence of intensive cycling training on heart rate variability during rest and exercise. 总被引:2,自引:0,他引:2
Anthony S Leicht Graham D Allen Andrew J Hoey 《Revue canadienne de physiologie appliquée》2003,28(6):898-909
The current study examined whether changes in heart rate variability (HRV) following intensive cycling training contribute to the mechanism of training-induced bradycardia. Thirteen healthy untrained subjects, ages 18-27 years, underwent recordings of heart rate (HR) and VO2max before and after 8 weeks of cycling, 25-60 min/day, 5 days/week at > 80% maximum HR (HRmax). Heart rate recordings were obtained during supine rest and submaximal exercise and were analysed for the following components of HRV: low frequency (LF, 0.041-0.15 Hz); high frequency (HF, 0.15-0.40 Hz); LF/HF ratio and total power (TP, 0-0.40 Hz). At posttraining, VO2max was significantly increased while HR was significantly reduced at rest and all absolute exercise work rates. Training-induced lower HR was accompanied by significantly greater HF and TP during rest as well as LF, HF, and TP during all absolute exercise work rates. Posttraining HR and the majority of HRV measures were similar to pretraining values at the same relative exercise intensity (% HRmax). These results indicated that 8 weeks of intensive cycling training increased HRV and cardiac vagal modulation during rest and absolute exercise work rates but had little effect during relative exercise work rates. Increased vagal modulation resulting from intensive exercise training may contribute to the mechanism of training-induced bradycardia. 相似文献
6.
Heart rate variability and its determinants in patients with severe or mild essential hypertension. 总被引:4,自引:0,他引:4
H Mussalo E Vanninen R Ik?heimo T Laitinen M Laakso E L?nsimies J Hartikainen 《Clinical physiology》2001,21(5):594-604
How cardiac autonomic nervous control is related to the severity of essential hypertension in patients receiving long-term antihypertensive therapy is not well known. The aim of this study was to examine heart rate variability (HRV), a non-invasive measure of cardiac autonomic function, in patients with long-term and medically treated mild and severe essential hypertension and healthy control subjects, and to assess the clinical determinants of HRV in these patients. Thirty-four patients with severe essential hypertension (SEHT) and 29 with mild essential hypertension (MEHT) as well as healthy age- and sex-matched control subjects were studied. HRV was assessed from 10 min ECG-recordings during paced (0.2 Hz) breathing at rest and expressed as time and frequency domain measures. In the SEHT group time (SDNN, RMSSD) and frequency domain measures (total power, low-frequency (LF) power and high-frequency (HF) power of HRV in absolute units, and LF and HF power of HRV in normalized units) of HRV were significantly lower when compared with those of the control group. The MEHT and control groups did not differ from each other with respect to time or frequency domain measures of HRV. Comparison between the hypertensive groups showed that SDNN, total power, LF power and HF power were lower in the SEHT group compared with the MEHT group (P<0.05 for all). Among hypertensive patients RR-interval, age, gender, systolic finger blood pressure and diastolic office blood pressure as well as 24-h blood pressure were significant determinants of HRV. In conclusion, we found that the severity of chronic essential hypertension seems to be related to the severity of impairment of cardiac autonomic control. 相似文献
7.
Assessment of autonomic nervous system with analysis of heart rate variability in children with spastic cerebral palsy 总被引:1,自引:0,他引:1
The purpose of this study was to investigate the function of the autonomic nervous system in children with spastic cerebral palsy (CP) through an analysis of heart rate variability (HRV) occurring with orthostatic stress. Twelve children with spastic CP and twelve normal children participated in this study. The echocardiogram (ECG) signals were recorded for 3 minutes in both the supine and 70 degrees C head-up tilt positions, and then the HRV signals underwent power spectrum analysis at each position. Two components were measured; a low- frequency (LF) component (0.05 - 0.15 Hz) primarily reflecting sympathetic activity during orthostatic stress and a high-frequency (HF) component (0.15 - 0.4 Hz) reflecting parasympathetic activity. In the supine position, there was no significant difference between any of the HRV components of the two groups. In the head-up tilt position, absolute and normalized LF were significantly increased and absolute HF was significantly decreased in the normal children (p < 0.05), but not in the children with spastic CP. The results of this study suggest that cardiac autonomic functions, such as vagal withdrawal and sympathetic activation which occur during head-up tilt position, are not sufficient to overcome the orthostatic stress arising in spastic CP children. 相似文献
8.
Schwab K Eiselt M Putsche P Helbig M Witte H 《Medical & biological engineering & computing》2006,44(12):1077-1083
The heart rate variability (HRV) can be taken as an indicator of the coordination of the cardio-respiratory rhythms. Bispectral
analysis using a direct (fast Fourier transform based) and time-invariant approach has shown the occurrence of a quadratic
phase coupling (QPC) between a low-frequency (LF: 0.1 Hz) and a high-frequency (HF: 0.4–0.6 Hz) component of the HRV during
quiet sleep in healthy neonates. The low-frequency component corresponds to the Mayer–Traube–Hering waves in blood pressure
and the high-frequency component to the respiratory sinus arrhythmia (RSA). Time-variant, parametric estimation of the bispectrum
provides the possibility of quantifying QPC in the time course. Therefore, the aim of this work was a parametric, time-variant
bispectral analysis of the neonatal HRV in the same neonates used in the direct, time-invariant approach. For the first time
rhythms in the time course of QPC between the HF component and the LF component could be shown in the neonatal HRV. 相似文献
9.
驾驶精神疲劳的心率变异性和血压变异性综合效应分析 总被引:7,自引:0,他引:7
驾驶精神疲劳是威胁人们健康与生命安全的严重问题.本研究的目的是基于心率变异性与血压变异性功率谱分析综合评估驾驶员精神疲劳.20个健康男性样本(28.8±4.3)岁参加90 min的模拟驾驶操作实验,实验后计算分析实验样本心率变异性和血压变异性的频域指标,如:低频成分(0.04~0.15 Hz,LF),高频成分(0.15~0.4Hz,HF),代频与高频比值(LF/HF);同时分析反映血流动力学指标的血压和心率.研究表明,样本在实验结束后交感神经兴奋性增强,迷走神经兴奋性减弱,交感迷走平衡性升高;同时,心率变异性与血压变异性的对应指标在实验过程中具有良好的相关性(P<0.05).研究认为采用多变量综合效应分析方式评价自主神经系统功能是科学和客观的. 相似文献
10.
Park DH Shin CJ Hong SC Yu J Ryu SH Kim EJ Shin HB Shin BH 《Journal of Korean medical science》2008,23(2):226-231
The risk of cardiovascular disease is known to be increased in obstructive sleep apnea syndrome (OSAS). Its mechanism can be explained by the observation that the sympathetic tone increases due to repetitive apneas accompanied by hypoxias and arousals during sleep. Heart rate variability (HRV) representing cardiac autonomic function is mediated by respiratory sinus arrhythmia, baroreflex-related fluctuation, and thermoregulation-related fluctuation. We evaluated the heart rate variability of OSAS patients during night to assess their relationship with the severity of the symptoms. We studied overnight polysomnographies of 59 male untreated OSAS patients with moderate to severe symptoms (mean age 45.4+/- 11.7 yr, apnea-hypopnea index [AHI]=43.2+/-23.4 events per hour, and AHI >15). Moderate (mean age 47.1+/-9.4 yr, AHI=15-30, n=22) and severe (mean age 44.5 +/-12.9 yr, AHI >30, n=37) OSAS patients were compared for the indices derived from time and frequency domain analysis of HRV, AHI, oxygen desaturation event index (ODI), arousal index (ArI), and sleep parameters. As a result, the severe OSAS group showed higher mean powers of total frequency (TF) (p=0.012), very low frequency (VLF) (p= 0.038), and low frequency (LF) (p=0.002) than the moderate OSAS group. The LF/HF ratio (p=0.005) was higher in the severe group compared to that of the moderate group. On the time domain analysis, the HRV triangular index (p=0.026) of severe OSAS group was significantly higher. AHI was correlated best with the LF/HF ratio (r(p))=0.610, p<0.001) of all the HRV indices. According to the results, the frequency domain indices tended to reveal the difference between the groups better than time domain indices. Especially the LF/HF ratio was thought to be the most useful parameter to estimate the degree of AHI in OSAS patients. 相似文献
11.
目的: 研究低体温与自主神经功能变化的关系。方法: 采用体表物理降温法逐步降低直肠温度,直肠温度变化范围为19-37 ℃。分别记录不同直肠温度下大鼠动态心电和血压信号。应用心率变异性和血压变异性分析系统评价低体温对心率变异性和收缩压变异性的影响。结果: 心率变异分析表明,直肠温度下降到29 ℃以下,R-R间期均延长(P<0.01),提示心率明显降低;当直肠温度下降到19-21 ℃时,心率变异归一化低频功率降低(P<0.05)和归一化高频功率增加(P<0.05),而且自主神经的平衡向心迷走神经张力增强的方向发生了转移(P<0.05)。血压变异性分析表明,体温下降到31℃时与呼吸有关的归一化高频功率开始增加(P<0.01);直肠温度下降到29 ℃以下(除27 ℃外),与呼吸有关的归一化高频功率增加(P<0.05或P<0.01),同时自主神经的平衡也发生了改变(P<0.05)。结论: 随着体温的降低,心血管迷走神经活性增加,自主神经的平衡向迷走神经张力增强的方向转移。低体温对血压变异性的影响敏感于心率变异性。 相似文献
12.
Taelman J Vandeput S Vlemincx E Spaepen A Van Huffel S 《European journal of applied physiology》2011,111(7):1497-1505
The cardiac regulation effects of a mental task added to regular office work are described. More insight into the time evolution
during the different tasks is created by using time–frequency analysis (TFA). Continuous wavelet transformation was applied
to create time series of instantaneous power and frequency in specified frequency bands (LF 0.04–0.15 Hz; HF 0.15–0.4 Hz),
in addition to the traditional linear heart rate variability (HRV) parameters. In a laboratory environment, 43 subjects underwent
a protocol with three active conditions: a clicking task with low mental load and a clicking task with high mental load (mental
arithmetic) performed twice, each followed by a rest condition. The heart rate and measures related to vagal modulation could
differentiate the active conditions from the rest condition, meaning that HRV is sensitive to any change in mental or physical
state. Differences between physical and mental stress were observed and a higher load in the combined task was observed. Mental
stress decreased HF power and caused a shift toward a higher instantaneous frequency in the HF band. TFA revealed habituation
to the mental load within the task (after 3 min) and between the two tasks with mental load. In conclusion, the use of TFA
in this type of analysis is important as it reveals extra information. The addition of a mental load to a physical task elicited
further effect on HRV parameters related to autonomic cardiac modulation. 相似文献
13.
14.
To explore whether depth of sleep is related to changes in autonomic control in rats, continuous power-spectral analysis of electroencephalogram (EEG) and heart rate variability (HRV) was performed in unanesthetized rats during normal daytime sleep. Quiet sleep (QS) was associated with an increase in high-frequency power of HRV (0.6-2.4 Hz, HF) but a decrease in low-frequency power (0.06-0.6 Hz) to HF ratio (LF/HF) compared with awakening. During QS, LF/HF was significantly and negatively correlated with delta power of EEG (0.5-4.0 Hz), whereas mean R-R interval and HF were not. As in humans, cardiac sympathetic regulation in rats is negatively related to the depth of sleep during QS, although vagal regulation is not. Our methodology offers a parallel way of studying the interaction between cerebral cortical and autonomic functions in rats. 相似文献
15.
To explore whether depth of sleep is related to changes in autonomic control, continuous power-spectral analysis of the electroencephalogram (EEG) and heart rate variability (HRV) was performed in ten normal subjects during nocturnal sleep. Quiet sleep (QS) was associated with an increase in high-frequency power (HF) of HRV (0.15-0.4 Hz) but a decrease in low-frequency power (LF) (0.04-0.15 Hz) to HF ratio (LF/HF) compared with awakening. During QS, LF/HF was significantly and negatively correlated with delta power of EEG (0.5-4.0 Hz), whereas mean R-R interval and HF were not. We conclude that during QS, cardiac sympathetic regulation is negatively related to the depth of sleep, although vagal regulation is not. Our methodology offers a quantitative analysis to study the interaction between cerebral cortical and autonomic functions. 相似文献
16.
Gustavo A. Reyes del Paso Wolf Langewitz Lambertus J. M. Mulder Arie van Roon Stefan Duschek 《Psychophysiology》2013,50(5):477-487
This article evaluates the suitability of low frequency (LF) heart rate variability (HRV) as an index of sympathetic cardiac control and the LF/high frequency (HF) ratio as an index of autonomic balance. It includes a comprehensive literature review and a reanalysis of some previous studies on autonomic cardiovascular regulation. The following sources of evidence are addressed: effects of manipulations affecting sympathetic and vagal activity on HRV, predictions of group differences in cardiac autonomic regulation from HRV, relationships between HRV and other cardiac parameters, and the theoretical and mathematical bases of the concept of autonomic balance. Available data challenge the interpretation of the LF and LF/HF ratio as indices of sympathetic cardiac control and autonomic balance, respectively, and suggest that the HRV power spectrum, including its LF component, is mainly determined by the parasympathetic system. 相似文献
17.
De Vries-Bouw M Popma A Vermeiren R Doreleijers TA Van De Ven PM Jansen LM 《Psychophysiology》2011,48(11):1597-1604
Low autonomic (re)activity is a consistent correlate of antisocial behavior in juveniles. However, longitudinal research relating autonomic measures to persistent antisocial behavior has remained scarce. Therefore, in the present study we examined the predictive value of heart rate (HR) and heart rate variability (HRV, often studied as respiratory sinus arrhythmia) for reoffending in delinquent male adolescents. At initial assessment, HR and HRV were measured at rest and in response to a public speaking task. Registered reoffending was assessed after 5-year follow-up. Attenuated HR response and stronger HRV response to stress predicted higher reoffending rates. Results provide evidence that HR/HRV reactivity are neurobiological markers for persistent juvenile antisocial behavior. Although effect sizes were small to moderate, our findings underscore the consistency of the relationship between autonomic markers and antisocial behavior. 相似文献
18.
Parabolic flight is used to create short successive periods of changing gravity in a range between 0 and 1.8 Gz (1 Gz: 9.81 m/s2). The purpose of the present study was to evaluate whether cyclic variations in heart rate during ±20 s periods of stable
gravity in parabolic flight reflect autonomic modulation of cardiac chronotropy. During the 29th and 32nd ESA parabolic flight
campaign ECG and respiration were recorded in 13 healthy volunteers in both standing and supine postures. We developed and
validated a spectral algorithm especially adapted to study frequency components of heart rate among ultrashort (±20 s) stable
gravity periods of parabolic flight. A low frequency (LF) component, starting from the lowest measurable frequency (±0.05 Hz)
up to 0.15 Hz was distinguished from a high frequency (HF) component, ranging from 0.16 Hz up to 0.4 Hz. Powers were calculated
by integration between corresponding limits and represented in normalized units (nu). With our method, we were able to reproduce
normal findings in the upright posture at 1 Gz, i.e., less power in the HF component compared to supine (HFnu: 0.18±0.09 vs.
0.40±0.16). These postural related differences are shown to be eliminated at 0 Gz (HFnu: 0.30±0.12 vs. 0.32±0.13) and amplified
at 1.8 Gz phases (HFnu: 0.15±0.10 vs. 0.39±0.16) of parabolic flight. In the supine position no coherent differences were
shown in the measured variables among different gravity phases. Our observations strongly indicate that spectral characteristics
of heart rate fluctuations among stable gravity periods of parabolic flight reflect parasympathetic nervous system control
of cardiac chronotropy. At 1 Gz, there is a normal upright situation with less parasympathetic modulation of heart rate compared
to supine. This effect is augmented during 1.8 Gz-conditions due to a suppressed parasympathetic control of heart rate in
the upright posture. Alternatively, at 0 Gz, increased parasympathetic control in standing position eliminates differences
in cardiac chronotropy compared to supine. 相似文献
19.
Rosa Brito-Zurita O Posadas-Romero C Hermosillo AG Zamora-González J Hernández-Ono A Cardoso-Saldaña G Torres-Tamayo M 《Maturitas》2003,44(1):39-48
Healthy postmenopausal women and hypertensive patients show an imbalance in the modulation of autonomic nervous control of the cardiovascular system, which may increase the cardiovascular risk. OBJECTIVE: To examine the heart rate variability (HRV) response to estrogen replacement therapy (ERT) and its association with changes in metabolic variables in hypertensive postmenopausal women. METHODS: A double-blind, placebo-controlled clinical trial was conducted in 30 hypertensive postmenopausal women receiving 180 mg/day of verapamil. The experimental group (n=16) received 0.625 mg OD of natural conjugated estrogens during 4 months, while control group (n=14) received a placebo. Lipids, lipoproteins, apolipoproteins, glucose and insulin were measured at 0, 2 and 4 months. HRV was determined in time and frequency domains using a 24-h Holter before and after ERT. RESULTS: Significant higher values of spectral and non-spectral parameters of HRV, associated with a lower LF/HF ratio, were found at the end of 4 months of ERT. Multiple regression analysis revealed that estrogen treatment itself and changes in total cholesterol, LDL-cholesterol, glucose and waist circumference, contributed to the changes observed in indexes reflecting parasympathetic activity in time and frequency domains. CONCLUSIONS: We conclude that ERT partially improves HRV favoring increased parasympathetic drive, and that part of the effect may be mediated by changes in metabolic variables. 相似文献
20.
We investigate whether pulse rate variability (PRV) extracted from finger photo-plethysmography (Pleth) waveforms can be the substitute of heart rate variability (HRV) from RR intervals of ECG signals during obstructive sleep apnea (OSA). Simultaneous measurements (ECG and Pleth) were taken from 29 healthy subjects during normal (undisturbed sleep) breathing and 22 patients with OSA during OSA events. Highly significant (p<0.01) correlations (1.0>r>0.95) were found between heart rate (HR) and pulse rate (PR). Bland-Altman plot of HR and PR shows good agreement (<5% difference). Comparison of 2 min recording epochs demonstrated significant differences (p<0.01) in time, frequency domains and complexity analysis, between normal and OSA events using PRV as well as HRV measures. Results suggest that both HRV and PRV indices could be used to distinguish OSA events from normal breathing during sleep. However, several variability measures (SDNN, RMSSD, HF power, LF/HF and sample entropy) of PR and HR were found to be significantly (p<0.01) different during OSA events. Therefore, we conclude that PRV provides accurate inter-pulse variability to measure heart rate variability under normal breathing in sleep but does not precisely reflect HRV in sleep disordered breathing. 相似文献