后疫情时代《微生物学与免疫学》课程思政的探索与实践

《微生物学与免疫学》是我院药学、中药学、医学检验技术专业教学体系中重要的专业基础课程之一。课程思政教育是以专业课堂为载体,以隐性方式将思想政治教育内容、要求和原则渗入。在疫情常态化防控背景下,对该课程思政进行积极探索和实践。本文从教学思政目标、教学内容与思政的映射、教学思政模式、教学思政育人团队和考核方式等方面对课程思政进行了改革与创新,将思政教育的普适性与药学行业的新业态相结合,从而塑造学生正确的人生观和价值观,培养学生们献身祖国医药科学事业,敢于钻研、迎难而上、孜孜不倦的求索奋斗精神。     

中医院校留学生的医学微生物与免疫学教学体会

医学微生物与免疫学是中医院校各专业的一门重要基础课程,也是一门较难讲解的课程,其课时少、内容多,对于留学生更是如此。针对本校留学生在教学中出现的问题,如教材和教学内容的选择、现代教学手段以及教师的选择等方面,笔者做了诸多尝试,在此将笔者的一些体会与各位同仁共同探讨,以期提高留学生的医学微生物与免疫学教学水平。     

高职护理专业《病原生物与免疫学》的教学初探

<正>《病原生物与免疫学》是由病原生物学与免疫学两部分组成,但是却包括了三门学科:医学微生物学、人体寄生虫学和医学免疫学。作为一门医学基础课程,具有很强的理论性和实践性。针对《病原生物与免疫学》多数内容繁杂,逻辑性较差,相对枯燥,学生普遍反映比较枯燥繁琐,不易记忆,在学习上深感困难的特点,结合不同知识     

酶工程专业课程的教学改革与思考

酶工程属于生物化学与分子生物学学科范畴,它是一门广泛地涉及生物学领域和生物工程学科理论的应用技术科学．是随着酶学研究迅速发展。特别是酶的应用推广使酶学和工程学相互渗透结合、发展而成的酶学、微生物学基本原理与化学工程有机结合而成的一门新技术学科,在工业、农业、医药、保健、环保及其他各方面发挥着重要作用。酶工程作为生物工程领域的重要内容,在相关专业开设专门课程的时间较晚,对酶工程课程教学的研究也较少,因此,结合酶工程课程教学实践,就如何做好该课程的教学工作．提高该课程教学质量等方面谈一些体会。     

病原生物与免疫学实验教学的几点体会

病原生物与免疫学是一门重要的医学基础课程,是学习其它医学知识的重要的桥梁和保证。但这门课程的研究对象都是一些肉眼看不见的微小生物以及抽象的免疫学知识。整个教学     

留学生医学微生物学的教学体会

随着经济的全球化和国家综合国力的提高．我国与国外的文化教育交流也不断深入。大量的海外学子进入我国高等医学院校,使留学生教育成为高等院校的一项重要的教学任务,这给改革发展中的高校提出了更高的要求。医学微生物学是医学留学生的一门重要基础必修课．与多门临床课程的学习密切相关。如何上好这门课,为临床学习打下坚实基础,是微生物学教师面临的重要问题。     

提高药理学课堂教学质量之刍议

药理学是一门研究药物与机体相互作用规律的一门科学,在教学过程中,需要运用生理学、生物化学、病理学、微生物学、免疫学等诸多基础学科的知识,同时还需要联系内科学、外科学、传染病学等临床学科知识.     

基础医学实验教学内容和体系改革的探索

我院基础医学实验室组建于2000年9月,涉及人体解剖学、组织学与胚胎学、细胞生物学、医学遗传学、生物化学、病理学、医学微生物学、人体寄生虫学、医学免疫学与机能实验学等课程。在基础医学教育的改革步伐和改革力度还远远不能适应社会发展的需要之时,面对机遇挑战,如何在教学中既注重学生专业知识和专业理论教育。又不忽视学生综合素质和实践能力的培养：     

本科生《医学免疫学》理论教学探讨

由于《医学免疫学》理论抽象、概念较多、发展迅速等学科特点,使其成为医科院校本科生感觉难学但又非常重要的一门基础医学课程。在多年的教学过程中我们不断改革和创新,探索一些行之有效的教学方式。首先,针对本科不同专业学生特点,以教材为主设置教学内容;其次在课堂理论教学过程中进行框架式导课、三级案例启发式教学并结合多种教学方式和教学手段;最后在课程中课程之后及时对学生进行评估反馈,通过五个方面的改进和探索来提高《医学免疫学》在本科生中理论教学效果。     

免疫学课堂教学形式及方法初探

医学免疫学是医学院校临床医学专业及其他相关专业的一门重要基础课程,该学科突出特点是理论深奥、抽象,学生难以理解,学习难度较大。如何深入浅出地讲授医学免疫学的基本理论体系,激发学生的学习兴趣,让学生喜欢学、容易学,听得懂、记得牢,是免疫学教学中一个值得不断探讨的课题,为提高教学效果,笔者就课堂教学形式及方法针对性地设计了若干问题,     

“医”与“法”

2003年8月中,惠氏百宫制药有限公司邀请广东地区各大医院的专家和医院管理人员在广东东莞举行了一场别开生面的研讨会。会议包括两个议题:一是“特治星治疗严重呼吸道感染”的学术研讨;二是“医疗纠纷处理的新规则与新思路”的研讨。会上“热点”不断,台上、台下观点撞击精彩纷呈,这里我们摘录片段与大家共享。     

Laboratory Verification of "heavy" and "light" users of cannabis

For various experimental studies it is often desirable to classify categories of cannabis use. For instance, in a study of the kinetics of δ-9-tetrahydrocannabinol (THC) in man, we wanted to see if there were differences between “heavy” and “light” users of the drug. “Heavy” use was defined as once daily or more, while “light” use was defined as sporadic or occasional, no more frequent than once monthly.Previously, we had found that the 11-oic acid of THC was not only the major metabolite to appear in the urine but also that its appearance in urine was prompt and lasted for at least 72 hours after a single exposure [1]. We decided to use the presence of this material in urine as a marker for heavy and light use; one would expect to find it regularly in heavy users and rarely, if at all, among light users. All subjects entering the study declared their pattern of use and then were asked to provide a spontaneously voided urine, to be used for analysis of THC-11-oic acid.     

以"豆"祛"痘"

虽然早已过了青春期,但我那略显"婴儿肥"的脸上还是会不时地出现些小痘痘.为了消除这些可恶的家伙,我还真是没少折腾,又是吃药、吃保健品,又是用化妆品,可痘痘却大有"野火烧不尽,春风吹又生"之势,看来要消灭它们可不是件容易的事.     

Activity of "reversed" diamidines against Trypanosoma cruzi "in vitro"

Chagas' disease is an important parasitic illness caused by the flagellated protozoan Trypanosoma cruzi. The disease affects nearly 17 million individuals in endemic areas of Latin America and the current chemotherapy is quite unsatisfactory based on nitroheterocyclic agents (nifurtimox and benznidazol). The need for new compounds with different modes of action is clear. Due to the broad-spectrum antimicrobial activity of the aromatic dicationic compounds, this study focused on the activity of four such diamidines (DB811, DB889, DB786, DB702) and a closely related diguanidine (DB711) against bloodstream trypomastigotes as well as intracellular amastigotes of T. cruzi in vitro. Additional studies were also conducted to access the toxicity of the compounds against mammalian cells in vitro. Our data show that the four diamidines compounds presented early and high anti-parasitic activity (IC50 in low-micromolecular range) exhibiting trypanocidal dose-dependent effects against both trypomastigote and amastigote forms of T. cruzi 2h after drug treatment. Most of the diamidines compounds (except the DB702) exerted high anti-parasitic activity and low toxicity to the mammalian cells. Our results show the activity of reversed diamidines against T. cruzi and suggested that the compounds merit in vivo studies.     

"Central" and "peripheral" benzodiazepines and kinetics of lindane-induced toxicity

Because hypothermia and anorexia were previously found to be more sensitive indices of the effects of lindane than were convulsions, these endpoints were used to quantify the ability of benzodiazepines (BDs) and phenytoin either to ameliorate or exacerbate the toxicity of lindane in the rat. After administration of lindane (40 or 50 mg/kg) in oil per os, toxicity was counteracted by phenytoin and the "central" BD agonists diazepam and clonazepam, but was worsened by Ro 5-4864 a "peripheral" BD agonist. Clonazepam and diazepam were each more effective in counteracting lindane-induced anorexia than in stimulating food intake, presumably because the animals had been fasted and probably even controls ate maximally when food was presented. Diazepam alone (3 injections in 1 day) produced withdrawal-induced decreased food intake the following day. Clonazepam and diazepam alone each transiently decreased colonic temperature, yet effectively blocked the more severe hypothermia produced by lindane. Ro 5-4864 by itself did not produce any measurable effects, yet exacerbated all of the effects, including lethal effects, of lindane. The present findings are compatible with other evidence that lindane and Ro 5-4864 act at the picrotoxinin receptor of the GABAA-activated chloride channel and that systemic administration of agents acting at this site may produce a constellation of effects, including seizures, hypothermia and anorexia.