纳米银敷料治疗烧伤创面的临床观察

目的 观察纳米银外用敷料对烧伤创面的治疗作用。方法 选择浅Ⅱ度及深Ⅱ度创面共116例，分别随机分为对照组54例(用皮维碘纱布换药)和治疗组62例(用皮维碘纳米银敷料换药)，观察创而渗出、炎症反应、浅Ⅱ度7d创面愈合率和深Ⅱ度创向14d创面愈合率、创面愈合时间，随访观察瘢痕增生情况，结果 与对照组比较，纳米银组创面下燥结痂快，炎症反应轻，创周炎症消退快。纳米银组：浅Ⅱ度7d愈合率68．4％，平均愈合时间8．3d；深Ⅱ度14d愈合率87．5％，平均愈合时间16．4d.对照组：浅Ⅱ度7d愈合率31．3％，平均愈合时间11．2d；深Ⅱ度14d愈合率59．1％，平均愈合时间19.8d。两组7d、14td愈合率和平均愈合时间比较差异均有显著性，随访10例瘢痕增生程度较轻。结论 纳米银是一种有效控制炎症反应，促进创面愈合的良好外用敷料，其能否减轻瘢痕增生尚需进一步观察。     

3种不同药物治疗浅Ⅱ度烧伤感染创面效果观察

目的筛选最佳浅Ⅱ度烧伤感染创面换药配方.方法将120例浅Ⅱ度烧伤感染创面病人随机分为A、B、C 3组各40例.A组采用紫花烧伤膏、紫草油加庆大霉素联合配方换药;B组用庆大霉素纱条湿敷;C组将紫花烧伤膏直接涂于创面.结果A组疗效明显优于B组(P＜0.05),与C组比较差异无显著性意义;换药,更换敷料时病人的疼痛感A、C两组优于B组(均P＜0.01);伤口换药次数及愈合时间A组明显少于B、C组(P＜0.05,P＜0.01).结论选用A组药物配方治疗浅Ⅱ度烧伤感染创面既可减少换药次数,减轻病人的疼痛,又可明显缩短伤口愈合时间,有助于烧伤感染创面的恢复,具有临床应用及推广价值.     

夫西地酸治疗浅Ⅱ度烧伤的疗效及对烧伤常见菌的体外抗菌活性探讨

目的：检测夫西地酸对烧伤常见菌的体外抗菌活性并观察夫西地酸治疗浅Ⅱ度烧伤的临床效果。方法：采用琼脂扩散法比较夫西地酸乳膏和磺胺嘧啶银软膏对耐甲氧西林的金黄色葡萄球菌（MRSA）、金黄色葡萄球菌（Sau）、表皮葡萄球菌（Sep）、铜绿假单胞菌（Pae）、大肠杆菌（Eco）的体外抗菌活性。选择2021年12月-2022年4月就诊的84例小面积浅Ⅱ度烧伤患者随机分为两组,使用夫西地酸乳膏治疗的42例患者为观察组;使用磺胺嘧啶银软膏治疗的42例患者为对照组,药物使用直至两组创面上皮化愈合。分别记录两组患者的创面愈合时间、1周创面愈合率、疼痛程度、分泌物培养阳性率、不良反应发生率。结果：体外实验中夫西地酸乳膏对MRSA、Sau、Sep的抑菌圈均大于磺胺嘧啶银软膏,差异有统计学意义（P<0.05）。临床观察中观察组创面完全愈合时间短于对照组（P<0.05）;观察组前3次用药后疼痛程度评分均小于对照组（P<0.05）;两组患者1周创面愈合率、使用药物前及使用药物后2～3?d、5～6?d创面分泌物培养阳性率结果比较,差异均无统计学意义（P>0.05）;两组患者不良反应比较差异无...     

湿性愈合疗法治疗慢性溃疡性伤口的效果观察

目的 探讨应用湿性愈合疗法治疗慢性溃疡性伤口的效果.方法 将24例慢性溃疡性伤口患者随机分为观察组(采用湿性愈合疗法)和对照组(采用传统疗法)各12例,并对两组患者的治愈时间和治疗费用进行比较.结果 观察组治愈时间和治疗费用分别为(25.08±8.02)d和(368.33±157.41)元,对照组分别为(38.33±20.04)d和(545.83±246.93)元,两组比较.差异有显著性意义(均P<0.05).结论 湿性愈合疗法更有助于慢性溃疡性伤口愈合,缩短治愈时间,降低治疗费用.     

烧伤Ⅲ号持续湿敷治疗下肢溃疡效果观察

目的 观察烧伤Ⅲ号持续湿敷治疗下肢皮肤溃疡的效果.方法 将33例下肢溃疡患者随机分为观察组(18例)和对照组(15例),观察组采用本院研制的烧伤Ⅲ号持续湿敷,对照组采用活力碘持续湿敷,观察两组治疗效果及溃疡愈合时间.结果 观察组总有效率显著高于对照组,溃疡愈合时间显著短于对照组(P＜0.05,P＜0.01).结论 下肢溃疡患者采用烧伤Ⅲ号持续湿敷效果确切,护理时间明显缩短.     

水胶体敷料在面颈部浅Ⅱ度烧伤治疗中的应用

目的：分析水胶体敷料在面颈部浅Ⅱ度烧伤创面治疗中的应用效果。方法：选取2019年7月-2021年3月医院收治的浅Ⅱ度面颈部烧伤患者120例作为研究对象,按随机数字表法分为观察组和对照组,对照组60例患者进行常规清创处理,观察组60例患者在常规治疗基础上予以水胶体敷料。比较两组治疗前及治疗后7 d、14 d数字化疼痛分级法(Numerical rating scale,NRS),比较两组创面愈合时间、感染情况及不良反应发生情况。结果：治疗后7 d、14 d相较于治疗前,两组NRS评分均明显降低,且观察组显著低于对照组,差异具有统计学意义(P<0.05)。观察组创面愈合时间明显低于对照组,差异具有统计学意义(P<0.05)。与对照组相比,观察组的感染总发生率更低,差异有统计学意义(6.67% vs 20.00%,P<0.05)。观察组不良反应总发生率为3.33%,对照组为5.00%,组间比较差异无统计学意义(P>0.05)。结论：水胶体敷料应用于面颈部浅Ⅱ度烧伤治疗中能有效减轻患者疼痛反应,缩短愈合时间,安全性较高。     

瘢痕贴与弹力绷带联合治疗烧伤后瘢痕增生

瘢痕组织是烧伤患者创面修复过程中的一种自然产物,是创面愈合的表现。但如果瘢痕组织过度增生,则会产生增生性瘢痕,使患者感到瘙痒、疼痛,甚至导致局部功能障碍等,因此减少瘢痕增生是每位烧伤患者的愿望。如何防治瘢痕形成一直是创伤修复领域研究的热点,但目前在瘢痕防治方面尚无有效的方法,本组采用瘢痕贴联合弹力绷带治疗烧伤患者,并对治疗后瘢痕的瘙痒、色泽、厚度及硬度进行了跟踪,同时与单纯使用瘢痕贴组相比较,现报道如下。     

荷负电气溶胶治疗Ⅱ度烧伤创面的临床效果及病理学观察

目的观察荷负电气溶胶(下称气溶胶)治疗Ⅱ度烧伤创面的效果。方法选择单纯浅Ⅱ、深Ⅱ度烧伤患者,随机分为:(1)气溶胶组:浅Ⅱ度180例、深Ⅱ度100例,伤后6h~2d开始用气溶胶治疗创面,l~2次/d,1.5h/次。(2)对照组:浅Ⅱ、深Ⅱ度患者各30例,常规治疗。(3)自身对照组:浅Ⅱ、深Ⅱ度患者各10例,同上用气溶胶治疗,但同一患者部分创面覆盖无菌金属片屏蔽气溶胶(屏蔽组),部分创面不屏蔽(非屏蔽组)。观察气溶胶治疗过程中患者创面的大体变化,治疗前后进行创面细菌培养,并监测其肝、肾功能及血生化指标有无改变。记录各组患者创面愈合时间。另制作深Ⅱ度烫伤大鼠模型,同前分为气溶胶组和对照组并治疗。取两组大鼠治疗前及治疗后1、2、3周的创面组织标本,作病理学观察。结果气溶胶治疗后患者创面渗出少,治疗前后均无细菌生长。总体来讲,气溶胶治疗前后患者肝、肾功能及血生化指标无明显改变。气溶胶组患者浅Ⅱ度创面伤后(6.3±1.6)d愈合,深Ⅱ度创面(15.1±3.1)d愈合,明显短于对照组相同深度创面[(11.3±1.4)、(21.2±1.4)d,P<0.01]。自身对照组中,相同烧伤深度的非屏蔽组与屏蔽组比较,创面愈合时间也明显缩短(P<0.01)。病理学检查显示,气溶胶组大鼠治疗后第3周皮肤结构已基本恢复正常,而对照组此时恢复较差。结论气溶胶能有效促进Ⅱ度烧伤创面的愈合且使用安全。     

自体富含血小板血浆凝胶治疗深Ⅱ度烧伤创面效果分析

目的 探讨自体富含血小板血浆凝胶治疗深Ⅱ度烧伤创面的效果。方法 回顾性分析中国人民解放军联勤保障部队第九八八医院2019-04—2021-06收治的58例深Ⅱ度烧伤创面患者的临床资料。分为自体富含血小板血浆凝胶外敷组(观察组)和1%磺胺嘧啶银冷霜外敷组(对照组),各29例。比较2组患者的创面愈合时间、创面换药次数、内层纱布更换次数,创面炎性分泌物消失时间,以及不同时间的创面愈合率和不良反应。结果 观察组患者的创面愈合时间、创面炎性分泌物消失时间均短于对照组,创面换药次数、内层纱布更换次数少于对照组,治疗后第10天、15天、20天创面愈合率均高于对照组。以上差异均有统计学意义(P<0.05)。2组患者治疗期间未出现局部及全身严重不良反应。结论 自体富含血小板血浆凝胶在深Ⅱ度烧伤创面治疗中能缩短创面愈合时间,减少换药次数,提高创面愈合率,无不良反应,具有较高的临床应用价值。     

A study of tape adhesive strength on endotracheal tubes

A method of assessing the adhesive bond of tapes used to secure endotracheal (ET) tubes is described. Five kinds of tape and six different ET tubes including two silicone rubber, wire-reinforced tubes were tested. There are significant differences in the adhesive strength of different tapes, and in the adhesive bond formed by different ET tube materials. On the Portex clear ET tube, silk tape adhered best (p less than 0.001), followed by waterproof, cloth, dermiclear, and micropore tapes. Adhesive bonding by silk tape was significantly greater (p less than 0.001) for the three clear ET tubes (Portex clear, NCC clear, and Portex ivory) than for the Portex blue and the silicone rubber, wire-reinforced ET tubes. All tapes showed very poor or negligible adhesion to the Sheridan and Portex reinforced ET tubes. Adhesion to these tubes was greatly improved by wrapping them tightly with an "op site" dressing prior to applying tape.     

Leak rate of latex gloves after tearing adhesive tape

Anesthesiologists use latex gloves to provide barrier protection against infectious disease or contamination while providing anesthetic services. The performance of these services often involves tearing tape. The purpose of this study was to test the effect of tearing adhesive tape on permeability of latex examination gloves and to test the effect of an adhesive-sparing moisturizing cream on permeability of latex gloves used to tear adhesive tape. In a blinded, randomized, controlled laboratory experiment, 48 nonsterile latex examination gloves (24 pairs) were randomized to 1 of 2 groups. Adhesive-sparing moisturizing cream, 0.1 mL, was applied to 12 glove pairs; the remaining 12 pairs served as controls. Each of the 24 pairs of gloves were used to tear five 4-cm strips of cloth adhesive tape from a standard 1 1/2-inch roll. After initial inspection for obvious tears, each glove was tested for leaks using the watertight test as specified by the American Society for Testing and Materials (ASTM). Data recorded included the identity of the investigator tearing tape, number of holes initially observed, number of holes observed from the ASTM test, location of holes, glove classification as right or left hand, and treatment group. Based on the study, the authors concluded that health care providers who tear adhesive tape while wearing latex gloves should be aware that there is a high probability that the gloves no longer form a protective barrier and that adhesive-sparing moisturizing cream applied before tape is torn increases barrier protection.     

Labelled adhesive tape for the identification of syringe contents

Labelled adhesive tape for the identification of syringe contents with suitable dispensers which can be obtained in the United Kingdom is described. The equipment can be obtained from the 3M Company at the following address: 3M United Kingdom Ltd., Converted Products, Wigmore Street, London W1A 1ET.     

Removal of perforated adhesive tape: dry versus solvent-assisted

This study compared the speed of dry removal of perforated adhesive tape from skin with some of the more commonly used solvents, namely acetone, arachis (peanut) oil, paraffin oil and saline. Twenty healthy volunteers had each of the solvents used on separate adhesive tapes applied circumferentially to their arms. Time to removal was recorded and analysed using the non-parametric sign test. The findings indicate that removing the tape dry was faster than using solvents, with the exception of acetone. Additionally, the researchers had difficulty cleaning the skin following the removal of tape when solvents were used. The solvents tended to cause some disintegration of the tape adhesive, which remained attached to the volunteers' skin and was difficult to remove. The researchers' preference is for dry removal of perforated adhesive tapes.